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Items: 1 to 50 of 102

1.

Low Oxygen Modulates Multiple Signaling Pathways, Increasing Self-Renewal, While Decreasing Differentiation, Senescence, and Apoptosis in Stromal MIAMI Cells.

Rios C, D'Ippolito G, Curtis KM, Delcroix GJ, Gomez LA, El Hokayem J, Rieger M, Parrondo R, de Las Pozas A, Perez-Stable C, Howard GA, Schiller PC.

Stem Cells Dev. 2016 Jun 1;25(11):848-60. doi: 10.1089/scd.2015.0362. Epub 2016 May 9.

2.

Hepatocyte growth factor and alternative splice variants - expression, regulation and implications in osteogenesis and bone health and repair.

Frisch RN, Curtis KM, Aenlle KK, Howard GA.

Expert Opin Ther Targets. 2016 Sep;20(9):1087-98. doi: 10.1517/14728222.2016.1162293. Epub 2016 Mar 21. Review.

3.

Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b-Mediated Malignant Progression.

Picon-Ruiz M, Pan C, Drews-Elger K, Jang K, Besser AH, Zhao D, Morata-Tarifa C, Kim M, Ince TA, Azzam DJ, Wander SA, Wang B, Ergonul B, Datar RH, Cote RJ, Howard GA, El-Ashry D, Torné-Poyatos P, Marchal JA, Slingerland JM.

Cancer Res. 2016 Jan 15;76(2):491-504. doi: 10.1158/0008-5472.CAN-15-0927. Epub 2016 Jan 7.

4.

TAp63γ and ΔNp63β promote osteoblastic differentiation of human mesenchymal stem cells: regulation by vitamin D3 Metabolites.

Curtis KM, Aenlle KK, Frisch RN, Howard GA.

PLoS One. 2015 Apr 7;10(4):e0123642. doi: 10.1371/journal.pone.0123642. eCollection 2015.

5.

Progerin expression disrupts critical adult stem cell functions involved in tissue repair.

Pacheco LM, Gomez LA, Dias J, Ziebarth NM, Howard GA, Schiller PC.

Aging (Albany NY). 2014 Dec;6(12):1049-63.

6.

Hepatocyte growth factor and p38 promote osteogenic differentiation of human mesenchymal stem cells.

Aenlle KK, Curtis KM, Roos BA, Howard GA.

Mol Endocrinol. 2014 May;28(5):722-30. doi: 10.1210/me.2013-1286. Epub 2014 Mar 27.

7.

24R,25-dihydroxyvitamin D3 promotes the osteoblastic differentiation of human mesenchymal stem cells.

Curtis KM, Aenlle KK, Roos BA, Howard GA.

Mol Endocrinol. 2014 May;28(5):644-58. doi: 10.1210/me.2013-1241. Epub 2014 Mar 5.

8.

Reply to Boslough et al.: Decades of comet research counter their claims.

Napier WM, Bunch TE, Kennett JP, Wittke JH, Tankersley KB, Kletetschka G, Howard GA, West A.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4171. No abstract available.

9.

Evidence for deposition of 10 million tonnes of impact spherules across four continents 12,800 y ago.

Wittke JH, Weaver JC, Bunch TE, Kennett JP, Kennett DJ, Moore AM, Hillman GC, Tankersley KB, Goodyear AC, Moore CR, Daniel IR Jr, Ray JH, Lopinot NH, Ferraro D, Israde-Alcántara I, Bischoff JL, DeCarli PS, Hermes RE, Kloosterman JB, Revay Z, Howard GA, Kimbel DR, Kletetschka G, Nabelek L, Lipo CP, Sakai S, West A, Firestone RB.

Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):E2088-97. doi: 10.1073/pnas.1301760110. Epub 2013 May 20.

10.

Very high-temperature impact melt products as evidence for cosmic airbursts and impacts 12,900 years ago.

Bunch TE, Hermes RE, Moore AM, Kennett DJ, Weaver JC, Wittke JH, DeCarli PS, Bischoff JL, Hillman GC, Howard GA, Kimbel DR, Kletetschka G, Lipo CP, Sakai S, Revay Z, West A, Firestone RB, Kennett JP.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):E1903-12. doi: 10.1073/pnas.1204453109. Epub 2012 Jun 18.

11.

Hepatocyte growth factor (HGF) and 1,25-dihydroxyvitamin D together stimulate human bone marrow-derived stem cells toward the osteogenic phenotype by HGF-induced up-regulation of VDR.

Chen K, Aenlle KK, Curtis KM, Roos BA, Howard GA.

Bone. 2012 Jul;51(1):69-77. doi: 10.1016/j.bone.2012.04.002. Epub 2012 Apr 12.

PMID:
22521434
12.

Human bone marrow-derived stem cell proliferation is inhibited by hepatocyte growth factor via increasing the cell cycle inhibitors p53, p21 and p27.

Chen K, Perez-Stable C, D'Ippolito G, Schiller PC, Roos BA, Howard GA.

Bone. 2011 Dec;49(6):1194-204. doi: 10.1016/j.bone.2011.08.023. Epub 2011 Aug 30.

PMID:
21907315
13.

Neuroprotective properties of marrow-isolated adult multilineage-inducible cells in rat hippocampus following global cerebral ischemia are enhanced when complexed to biomimetic microcarriers.

Garbayo E, Raval AP, Curtis KM, Della-Morte D, Gomez LA, D'Ippolito G, Reiner T, Perez-Stable C, Howard GA, Perez-Pinzon MA, Montero-Menei CN, Schiller PC.

J Neurochem. 2011 Dec;119(5):972-88. doi: 10.1111/j.1471-4159.2011.07272.x. Epub 2011 May 13.

14.

Changes in the expression of genes associated with intraneuronal amyloid-beta and tau in Alzheimer's disease.

Fujimura RK, Reiner T, Ma F, Phillips V, de las Pozas A, Dickson DW, Roos BA, Howard GA, Perez-Stable C.

J Alzheimers Dis. 2010;19(1):97-109. doi: 10.3233/JAD-2010-1216.

15.

Evidence for an extraterrestrial impact 12,900 years ago that contributed to the megafaunal extinctions and the Younger Dryas cooling.

Firestone RB, West A, Kennett JP, Becker L, Bunch TE, Revay ZS, Schultz PH, Belgya T, Kennett DJ, Erlandson JM, Dickenson OJ, Goodyear AC, Harris RS, Howard GA, Kloosterman JB, Lechler P, Mayewski PA, Montgomery J, Poreda R, Darrah T, Hee SS, Smith AR, Stich A, Topping W, Wittke JH, Wolbach WS.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16016-21. Epub 2007 Sep 27.

16.

Isolation and characterization of marrow-isolated adult multilineage inducible (MIAMI) cells.

D'Ippolito G, Howard GA, Roos BA, Schiller PC.

Exp Hematol. 2006 Nov;34(11):1608-10. No abstract available.

PMID:
17046585
17.

Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells.

D'Ippolito G, Diabira S, Howard GA, Roos BA, Schiller PC.

Bone. 2006 Sep;39(3):513-22. Epub 2006 Apr 17.

PMID:
16616713
18.

Sustained stromal stem cell self-renewal and osteoblastic differentiation during aging.

D'Ippolito G, Howard GA, Roos BA, Schiller PC.

Rejuvenation Res. 2006 Spring;9(1):10-9.

PMID:
16608390
19.

Androgen-induced mineralization by MC3T3-E1 osteoblastic cells reveals a critical window of hormone responsiveness.

Balkan W, Burnstein KL, Schiller PC, Perez-Stable C, D'Ippolito G, Howard GA, Roos BA.

Biochem Biophys Res Commun. 2005 Mar 18;328(3):783-9.

PMID:
15694414
20.

Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential.

D'Ippolito G, Diabira S, Howard GA, Menei P, Roos BA, Schiller PC.

J Cell Sci. 2004 Jun 15;117(Pt 14):2971-81. Epub 2004 Jun 1.

21.

Autosomal dominant hyperostosis/osteosclerosis with high serum alkaline phosphatase activity.

Hernandez-Cassis C, Vogel CK, Hernandez TP, Econs MJ, Iglesias M, Iglesias A, Levis S, Roos BA, Howard GA, Iglesias Gamarra A.

J Clin Endocrinol Metab. 2003 Jun;88(6):2650-5.

PMID:
12788869
22.

Cooperative actions of hepatocyte growth factor and 1,25-dihydroxyvitamin D3 in osteoblastic differentiation of human vertebral bone marrow stromal cells.

D'Ippolito G, Schiller PC, Perez-stable C, Balkan W, Roos BA, Howard GA.

Bone. 2002 Aug;31(2):269-75.

PMID:
12151078
23.

The G gamma / T-15 transgenic mouse model of androgen-independent prostate cancer: target cells of carcinogenesis and the effect of the vitamin D analogue EB 1089.

Perez-Stable CM, Schwartz GG, Farinas A, Finegold M, Binderup L, Howard GA, Roos BA.

Cancer Epidemiol Biomarkers Prev. 2002 Jun;11(6):555-63.

24.

2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer.

Qadan LR, Perez-Stable CM, Anderson C, D'Ippolito G, Herron A, Howard GA, Roos BA.

Biochem Biophys Res Commun. 2001 Aug 3;285(5):1259-66.

PMID:
11478793
25.
26.

Gap-junctional communication is required for the maturation process of osteoblastic cells in culture.

Schiller PC, D'Ippolito G, Balkan W, Roos BA, Howard GA.

Bone. 2001 Apr;28(4):362-9.

PMID:
11336916
27.

Inhibition of gap-junctional communication induces the trans-differentiation of osteoblasts to an adipocytic phenotype in vitro.

Schiller PC, D'Ippolito G, Brambilla R, Roos BA, Howard GA.

J Biol Chem. 2001 Apr 27;276(17):14133-8. Epub 2001 Jan 25.

28.

Cyclosporin A affects extracellular matrix synthesis and degradation by mouse MC3T3-E1 osteoblasts in vitro.

Fornoni A, Cornacchia F, Howard GA, Roos BA, Striker GE, Striker LJ.

Nephrol Dial Transplant. 2001 Mar;16(3):500-5.

PMID:
11239022
29.

Gap-junctional communication mediates parathyroid hormone stimulation of mineralization in osteoblastic cultures.

Schiller PC, D'Ippolito G, Balkan W, Roos BA, Howard GA.

Bone. 2001 Jan;28(1):38-44.

PMID:
11165941
30.

Hepatocyte growth factor and vitamin D cooperatively inhibit androgen-unresponsive prostate cancer cell lines.

Qadan LR, Perez-Stable CM, Schwall RH, Burnstein KL, Ostenson RC, Howard GA, Roos BA.

Endocrinology. 2000 Jul;141(7):2567-73.

PMID:
10875259
31.
32.

Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow.

D'Ippolito G, Schiller PC, Ricordi C, Roos BA, Howard GA.

J Bone Miner Res. 1999 Jul;14(7):1115-22.

33.

Testes exhibit elevated expression of calcitonin gene-related peptide receptor component protein.

Balkan W, Oates EL, Howard GA, Roos BA.

Endocrinology. 1999 Mar;140(3):1459-69.

PMID:
10067875
34.
35.

Absence of androgen-mediated transcriptional effects in osteoblastic cells despite presence of androgen receptors.

Czerwiec FS, Liaw JJ, Liu SB, Perez-Stable C, Grumbles R, Howard GA, Roos BA, Burnstein KL.

Bone. 1997 Jul;21(1):49-56.

PMID:
9213007
36.

Hepatocyte growth factor and its actions in growth plate chondrocytes.

Grumbles RM, Howell DS, Wenger L, Altman RD, Howard GA, Roos BA.

Bone. 1996 Sep;19(3):255-61.

PMID:
8873966
38.

Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP.

Mehta PP, Lokeshwar BL, Schiller PC, Bendix MV, Ostenson RC, Howard GA, Roos BA.

Mol Carcinog. 1996 Jan;15(1):18-32.

PMID:
8561862
39.

Calcitonin gene-related peptide (CGRP) in the developing mouse limb.

Bidegain M, Roos BA, Hill EL, Howard GA, Balkan W.

Endocr Res. 1995 Nov;21(4):743-55.

PMID:
8582325
40.
41.

Cartilage metalloproteases in disuse atrophy.

Grumbles RM, Howell DS, Howard GA, Roos BA, Setton LA, Mow VC, Ratcliffe A, Muller FJ, Altman RD.

J Rheumatol Suppl. 1995 Feb;43:146-8.

PMID:
7538586
43.

An assessment of the anabolic skeletal actions of the common-region peptides derived from the CGRP and calcitonin prohormones.

Burns DM, Howard GA, Roos BA.

Ann N Y Acad Sci. 1992 Jun 30;657:50-62. No abstract available.

PMID:
1637109
44.
45.

Ethanol inhibits human bone cell proliferation and function in vitro.

Friday KE, Howard GA.

Metabolism. 1991 Jun;40(6):562-5.

PMID:
1865819
46.

Identification of a low molecular weight inhibitor of osteoblast mitogenesis in uremic plasma.

Andress DL, Howard GA, Birnbaum RS.

Kidney Int. 1991 May;39(5):942-5.

47.
48.
49.

Procalcitonin's amino-terminal cleavage peptide is a bone-cell mitogen.

Burns DM, Forstrom JM, Friday KE, Howard GA, Roos BA.

Proc Natl Acad Sci U S A. 1989 Dec;86(23):9519-23.

50.

Parathyroid hormone potentiates the effect of insulin-like growth factor-I on bone formation.

Spencer EM, Si EC, Liu CC, Howard GA.

Acta Endocrinol (Copenh). 1989 Sep;121(3):435-42.

PMID:
2800920

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