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Combining Procalcitonin and Rapid Multiplex Respiratory Virus Testing for Antibiotic Stewardship in Older Adult Patients With Severe Acute Respiratory Infection.

Lee CC, Chang JC, Mao XW, Hsu WT, Chen SY, Chen YC, How CK.

J Am Med Dir Assoc. 2019 Nov 29. pii: S1525-8610(19)30701-7. doi: 10.1016/j.jamda.2019.09.020. [Epub ahead of print]


Impact of renin-angiotensin-aldosterone system activation and body weight change on N-terminal pro-B-type natriuretic peptide variation in 100-km ultramarathon runners.

Li LH, Kao WF, Chiu YH, Hou SK, Meng C, How CK.

J Chin Med Assoc. 2019 Nov 15. doi: 10.1097/JCMA.0000000000000227. [Epub ahead of print]


Hospital outcomes and cumulative burden from complications in type 2 diabetic sepsis patients: a cohort study using administrative and hospital-based databases.

Hsieh MS, Hu SY, How CK, Seak CJ, Hsieh VC, Lin JW, Chen PC.

Ther Adv Endocrinol Metab. 2019 Sep 23;10:2042018819875406. doi: 10.1177/2042018819875406. eCollection 2019.


Factors associated with muscle mass in community-dwelling older people in Singapore: Findings from the SHIELD study.

Tey SL, Chew STH, How CH, Yalawar M, Baggs G, Chow WL, Cheong M, Ong RHS, Husain FS, Kwan SC, Tan CYL, Low YL, Tan NC, Huynh DTT.

PLoS One. 2019 Oct 9;14(10):e0223222. doi: 10.1371/journal.pone.0223222. eCollection 2019.


Sexual matters among teenagers.

Lee RMK, How CH, Rajasegaran K.

Singapore Med J. 2019 Sep;60(9):439-445. doi: 10.11622/smedj.2019112.


Detection and characterization of a novel bat-borne coronavirus in Singapore using multiple molecular approaches.

Lim XF, Lee CB, Pascoe SM, How CB, Chan S, Tan JH, Yang X, Zhou P, Shi Z, Sessions OM, Wang LF, Ng LC, Anderson DE, Yap G.

J Gen Virol. 2019 Oct;100(10):1363-1374. doi: 10.1099/jgv.0.001307. Epub 2019 Aug 16.


Autism spectrum disorder: early identification and management in primary care.

Tsang LPM, How CH, Yeleswarapu SP, Wong CM.

Singapore Med J. 2019 Jul;60(7):324-328. doi: 10.11622/smedj.2019070.


Impact of angiotension I converting enzyme gene I/D polymorphism on running performance, lipid, and biochemical parameters in ultra-marathoners.

Chiu YH, Lai JI, Tseng CY, Wang SH, Li LH, Kao WF, How CK, Chang WH, Hsieh CY.

Medicine (Baltimore). 2019 Jul;98(29):e16476. doi: 10.1097/MD.0000000000016476.


Enhanced anti-mammary gland cancer activities of tamoxifen-loaded erythropoietin-coated drug delivery system.

Beh CY, Rasedee A, Selvarajah GT, Yazan LS, Omar AR, Foong JN, How CW, Foo JB.

PLoS One. 2019 Jul 10;14(7):e0219285. doi: 10.1371/journal.pone.0219285. eCollection 2019.


Management of scabies.

Vasanwala FF, Ong CY, Aw CWD, How CH.

Singapore Med J. 2019 Jun;60(6):281-285. doi: 10.11622/smedj.2019058.


Early life exposure to di(2-ethylhexyl)phthalate causes age-related declines associated with insulin/IGF-1-like signaling pathway and SKN-1 in Caenorhabditis elegans.

How CM, Yen PL, Wei CC, Li SW, Liao VH.

Environ Pollut. 2019 Aug;251:871-878. doi: 10.1016/j.envpol.2019.04.141. Epub 2019 May 15.


Preadmission Antihypertensive Drug Use and Sepsis Outcome: Impact of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin Receptor Blockers (ARBs).

Hsieh MS, How CK, Hsieh VC, Chen PC.

Shock. 2019 May 21. doi: 10.1097/SHK.0000000000001382. [Epub ahead of print]


Serological evidence of continued Japanese encephalitis virus transmission in Singapore nearly three decades after end of pig farming.

Yap G, Lim XF, Chan S, How CB, Humaidi M, Yeo G, Mailepessov D, Kong M, Lai YL, Okumura C, Ng LC.

Parasit Vectors. 2019 May 17;12(1):244. doi: 10.1186/s13071-019-3501-0.


Tick-crocodilian interactions: a review, with the first record of tick (Acari: Ixodidae) infestation in the saltwater crocodile (Crocodylus porosus), and a concise host-parasite index.

Kwak ML, Foo M, Pocklington K, Hsu CD, Cheong W, How CB, Shunari M, Tahir MG.

Exp Appl Acarol. 2019 May;78(1):127-132. doi: 10.1007/s10493-019-00378-0. Epub 2019 May 15. Review.


An approach to problem behaviours in children.

Lulla D, Mascarenhas SS, How CH, Yeleswarapu SP.

Singapore Med J. 2019 Apr;60(4):168-172. doi: 10.11622/smedj.2019034.


Developmental delay: identification and management at primary care level.

Choo YY, Agarwal P, How CH, Yeleswarapu SP.

Singapore Med J. 2019 Mar;60(3):119-123. doi: 10.11622/smedj.2019025.


Characterization of Fowlpox virus in chickens and bird-biting mosquitoes: a molecular approach to investigating Avipoxvirus transmission.

Yeo G, Wang Y, Chong SM, Humaidi M, Lim XF, Mailepessov D, Chan S, How CB, Lin YN, Huangfu T, Fernandez CJ, Hapuarachchi HC, Yap G.

J Gen Virol. 2019 May;100(5):838-850. doi: 10.1099/jgv.0.001209. Epub 2019 Mar 25.


Developmental assessment: practice tips for primary care physicians.

Choo YY, Yeleswarapu SP, How CH, Agarwal P.

Singapore Med J. 2019 Feb;60(2):57-62. doi: 10.11622/smedj.2019016.


In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells.

Nordin N, Yeap SK, Rahman HS, Zamberi NR, Abu N, Mohamad NE, How CW, Masarudin MJ, Abdullah R, Alitheen NB.

Sci Rep. 2019 Feb 7;9(1):1614. doi: 10.1038/s41598-018-38214-x.


A practical clinical approach to liver fibrosis.

Kumar R, Teo EK, How CH, Wong TY, Ang TL.

Singapore Med J. 2018 Dec;59(12):628-633. doi: 10.11622/smedj.2018145.


Managing polycystic ovary syndrome in primary care.

Lua ACY, How CH, King TFJ.

Singapore Med J. 2018 Nov;59(11):567-571. doi: 10.11622/smedj.2018135.


Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells.

Foong JN, Selvarajah GT, Rasedee A, Rahman HS, How CW, Beh CY, Teo GY, Ku CL.

Biomed Res Int. 2018 Oct 15;2018:8691569. doi: 10.1155/2018/8691569. eCollection 2018.


Managing challenging behaviours in dementia.

Ooi CH, Yoon PS, How CH, Poon NY.

Singapore Med J. 2018 Oct;59(10):514-518. doi: 10.11622/smedj.2018125.


Response to "Letter to the editor re: Cheng YH, Chou WC, Yang YF, et al. Environ Sci Pollut Res (2018).".

Cheng YH, Chou WC, Yang YF, Huang CW, How CM, Chen SC, Chen WY, Hsieh NH, Lin YJ, You SH, Liao CM.

Environ Sci Pollut Res Int. 2018 Nov;25(33):33836-33839. doi: 10.1007/s11356-018-3178-5. Epub 2018 Sep 13. No abstract available.


Evaluation of pleurodesis by poly-ε-caprolactone (PCL) gel in an animal model using New Zealand white rabbits.

How CH, Lin CW, Lin YC, Young TH, Chen KC, Chen JS.

Asian J Surg. 2019 Mar;42(3):495-500. doi: 10.1016/j.asjsur.2018.07.001. Epub 2018 Aug 10.


Thymoquinone loaded in nanostructured lipid carrier showed enhanced anticancer activity in 4T1 tumor-bearing mice.

Ong YS, Saiful Yazan L, Ng WK, Abdullah R, Mustapha NM, Sapuan S, Foo JB, Tor YS, How CW, Abd Rahman N, Zakarial Ansar FH.

Nanomedicine (Lond). 2018 Jul;13(13):1567-1582. doi: 10.2217/nnm-2017-0322. Erratum in: Nanomedicine (Lond). 2019 Jun;14(11):1513.


Diabetes Shared Care Program (DSCP) and risk of infection mortality: a nationwide cohort study using administrative claims data in Taiwan.

Chen CH, Ma SH, Hu SY, Chang CM, Chiang JH, Hsieh VC, Yen DH, How CK, Hsieh MS.

BMJ Open. 2018 Jul 12;8(7):e021382. doi: 10.1136/bmjopen-2017-021382.


Corrigendum: Approach to frailty in the elderly in primary care and the community.

Chen CY, Gan P, How CH.

Singapore Med J. 2018 Jun;59(6):338. doi: 10.11622/smedj.2018074. No abstract available.


Dementia management: a brief overview for primary care clinicians.

Poon NY, Ooi CH, How CH, Yoon PS.

Singapore Med J. 2018 Jun;59(6):295-299. doi: 10.11622/smedj.2018070.


Chronic exposure to triadimenol at environmentally relevant concentration adversely affects aging biomarkers in Caenorhabditis elegans associated with insulin/IGF-1 signaling pathway.

How CM, Li SW, Liao VH.

Sci Total Environ. 2018 Nov 1;640-641:485-492. doi: 10.1016/j.scitotenv.2018.05.314. Epub 2018 Jun 1.


Approach to frailty in the elderly in primary care and the community.

Chen CY, Gan P, How CH.

Singapore Med J. 2018 May;59(5):240-245. doi: 10.11622/smedj.2018052. Erratum in: Singapore Med J. 2018 Jun;59(6):338.


Biofilm formation is not associated with worse outcome in Acinetobacter baumannii bacteraemic pneumonia.

Wang YC, Huang TW, Yang YS, Kuo SC, Chen CT, Liu CP, Liu YM, Chen TL, Chang FY, Wu SH, How CK, Lee YT.

Sci Rep. 2018 May 8;8(1):7289. doi: 10.1038/s41598-018-25661-9.


Esophageal Metal Stents with Concurrent Chemoradiation Therapy for Locally Advanced Esophageal Cancer: Safe or Not?

Lu YF, Chung CS, Liu CY, Shueng PW, Wu LJ, Hsu CX, Kuo DY, Hou PY, Chou HL, Leong KI, How CH, Chou SF, Wang LY, Hsieh CH.

Oncologist. 2018 Dec;23(12):1426-1435. doi: 10.1634/theoncologist.2017-0646. Epub 2018 May 4.


Prolonged exposure of di(2-ethylhexyl) phthalate induces multigenerational toxic effects in Caenorhabditis elegans.

Li SW, How CM, Liao VH.

Sci Total Environ. 2018 Sep 1;634:260-266. doi: 10.1016/j.scitotenv.2018.03.355. Epub 2018 Apr 5.


Copper complex derived from S-benzyldithiocarbazate and 3-acetylcoumarin induced apoptosis in breast cancer cell.

Foo JB, Low ML, Lim JH, Lor YZ, Zainol Abidin R, Eh Dam V, Abdul Rahman N, Beh CY, Chan LC, How CW, Tor YS, Saiful Yazan L.

Biometals. 2018 Aug;31(4):505-515. doi: 10.1007/s10534-018-0096-4. Epub 2018 Apr 5.


Approach to the forgetful patient.

Yoon PS, Ooi CH, How CH.

Singapore Med J. 2018 Mar;59(3):121-125. doi: 10.11622/smedj.2018026.


Authors' reply.

Chan HBY, How CH, Ng CW.

Singapore Med J. 2018 Mar;59(3):165. No abstract available.


Pattern of non-trauma emergency department resource utilization in older adults: An 8-year experience in Taiwan.

Chang JC, Yuan ZH, Lee IH, Hsu TF, How CK, Yen DH.

J Chin Med Assoc. 2018 Jun;81(6):552-558. doi: 10.1016/j.jcma.2017.10.008. Epub 2018 Feb 1.


Authors' reply.

Chan HBY, How CH, Ng CW.

Singapore Med J. 2018 Jan;59(1):61. doi: 10.11622/smedj.2018009. No abstract available.


Characterization and toxicity of citral incorporated with nanostructured lipid carrier.

Nordin N, Yeap SK, Zamberi NR, Abu N, Mohamad NE, Rahman HS, How CW, Masarudin MJ, Abdullah R, Alitheen NB.

PeerJ. 2018 Jan 4;6:e3916. doi: 10.7717/peerj.3916. eCollection 2018.


Changes of heart rate variability predicting patients with acute exacerbation of chronic obstructive pulmonary disease requiring hospitalization after Emergency Department treatment.

Tseng CY, Chang JC, Chen YC, Huang HH, Lin CS, How CK, Yen DH.

J Chin Med Assoc. 2018 Jan;81(1):47-52. doi: 10.1016/j.jcma.2017.10.003. Epub 2017 Dec 15.


Physical therapy in the management of frozen shoulder.

Chan HBY, Pua PY, How CH.

Singapore Med J. 2017 Dec;58(12):685-689. doi: 10.11622/smedj.2017107.


Selective serotonin reuptake inhibitors and the risk of hepatocellular carcinoma in hepatitis B virus-infected patients.

Chang CM, Hsieh MS, Yang TC, Hsieh VC, Chiang JH, Huang HH, How CK, Hu SY, Yen DH.

Cancer Manag Res. 2017 Nov 28;9:709-720. doi: 10.2147/CMAR.S148097. eCollection 2017.


PBPK/PD assessment for Parkinson's disease risk posed by airborne pesticide paraquat exposure.

Cheng YH, Chou WC, Yang YF, Huang CW, How CM, Chen SC, Chen WY, Hsieh NH, Lin YJ, You SH, Liao CM.

Environ Sci Pollut Res Int. 2018 Feb;25(6):5359-5368. doi: 10.1007/s11356-017-0875-4. Epub 2017 Dec 5.


Definitive tests for dengue fever: when and which should I use?

Chan HBY, How CH, Ng CW.

Singapore Med J. 2017 Nov;58(11):632-635. doi: 10.11622/smedj.2017100.


The changes of red blood cell viscoelasticity and sports anemia in male 24-hr ultra-marathoners.

Liu CH, Tseng YF, Lai JI, Chen YQ, Wang SH, Kao WF, Li LH, Chiu YH, How CK, Chang WH.

J Chin Med Assoc. 2018 May;81(5):475-481. doi: 10.1016/j.jcma.2017.09.011. Epub 2017 Nov 10.


Traumatic left main bronchial rupture: delayed but successful outcome of robotic-assisted reconstruction.

Wang HC, How CH, Lin HF, Lee JM.

Respirol Case Rep. 2017 Oct 23;6(1):e00278. doi: 10.1002/rcr2.278. eCollection 2018 Jan.


Authors' reply.

Poulose V, How CH.

Singapore Med J. 2017 Sep;58(9):573. doi: 10.11622/smedj.2017091. No abstract available.


Managing depression in primary care.

Ng CW, How CH, Ng YP.

Singapore Med J. 2017 Aug;58(8):459-466. doi: 10.11622/smedj.2017080. Review.

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