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Items: 35


The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling.

Abdel-Nour M, Carneiro LAM, Downey J, Tsalikis J, Outlioua A, Prescott D, Da Costa LS, Hovingh ES, Farahvash A, Gaudet RG, Molinaro R, van Dalen R, Lau CCY, Azimi FC, Escalante NK, Trotman-Grant A, Lee JE, Gray-Owen SD, Divangahi M, Chen JJ, Philpott DJ, Arnoult D, Girardin SE.

Science. 2019 Jul 5;365(6448). pii: eaaw4144. doi: 10.1126/science.aaw4144.


Short communication: Assessment of biomarkers of inflammation in the vaginal discharge of postpartum dairy cows diagnosed with clinical metritis.

Barragan AA, Lakritz J, Carman MK, Bas S, Hovingh E, Schuenemann GM.

J Dairy Sci. 2019 Aug;102(8):7469-7475. doi: 10.3168/jds.2018-15854. Epub 2019 Jun 13.


Diversity of Extended-Spectrum Cephalosporin-Resistant Escherichia coli in Feces from Calves and Cows on Pennsylvania Dairy Farms.

Salaheen S, Cao H, Sonnier JL, Kim SW, Del Collo LP, Hovingh E, Karns JS, Haley BJ, Van Kessel JAS.

Foodborne Pathog Dis. 2019 May;16(5):368-370. doi: 10.1089/fpd.2018.2579. Epub 2019 Feb 4.


Antimicrobial Resistance Among Escherichia coli Isolated from Veal Calf Operations in Pennsylvania.

Salaheen S, Kim SW, Cao H, Wolfgang DR, Hovingh E, Karns JS, Haley BJ, Van Kessel JAS.

Foodborne Pathog Dis. 2019 Jan;16(1):74-80. doi: 10.1089/fpd.2018.2530.


Age-Associated Distribution of Antimicrobial-Resistant Salmonella enterica and Escherichia coli Isolated from Dairy Herds in Pennsylvania, 2013-2015.

Cao H, Pradhan AK, Karns JS, Hovingh E, Wolfgang DR, Vinyard BT, Kim SW, Salaheen S, Haley BJ, Van Kessel JAS.

Foodborne Pathog Dis. 2019 Jan;16(1):60-67. doi: 10.1089/fpd.2018.2519. Epub 2018 Dec 31.


NOD1 and NOD2 in inflammation, immunity and disease.

Mukherjee T, Hovingh ES, Foerster EG, Abdel-Nour M, Philpott DJ, Girardin SE.

Arch Biochem Biophys. 2019 Jul 30;670:69-81. doi: 10.1016/ Epub 2018 Dec 19. Review.


Erratum for Byukusenge et al., "Complete Genome Sequences of Four Bovine Coronavirus Isolates from Pennsylvania".

Byukusenge M, Nissly RH, Kasibhatla SM, Li L, Russell R, Springer H, Barry R, Van Saun R, Wolfgang D, Hovingh E, Kulkarni-Kale U, Kuchipudi SV.

Microbiol Resour Announc. 2018 Jul 19;7(2). pii: e00845-18. doi: 10.1128/MRA.00845-18. eCollection 2018 Jul.


Antimicrobial Resistance in Fecal Escherichia coli and Salmonella enterica from Dairy Calves: A Systematic Review.

Springer HR, Denagamage TN, Fenton GD, Haley BJ, Van Kessel JAS, Hovingh EP.

Foodborne Pathog Dis. 2019 Jan;16(1):23-34. doi: 10.1089/fpd.2018.2529. Epub 2018 Nov 27.


Detection of opsonizing antibodies directed against a recently circulating Bordetella pertussis strain in paired plasma samples from symptomatic and recovered pertussis patients.

Hovingh ES, Kuipers B, Bonačić Marinović AA, Jan Hamstra H, Hijdra D, Mughini Gras L, van Twillert I, Jongerius I, van Els CACM, Pinelli E.

Sci Rep. 2018 Aug 13;8(1):12039. doi: 10.1038/s41598-018-30558-8.


Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor.

Hovingh ES, de Maat S, Cloherty APM, Johnson S, Pinelli E, Maas C, Jongerius I.

Front Immunol. 2018 Jun 4;9:1172. doi: 10.3389/fimmu.2018.01172. eCollection 2018.


Complete Genome Sequences of Four Bovine Coronavirus Isolates from Pennsylvania.

Byukusenge M, Nissly RH, Kasibhatla SM, Li L, Russell R, Springer H, Barry R, Van Saun R, Wolfgang D, Hovingh E, Kulkarni-Kale U, Kuchipudi SV.

Genome Announc. 2018 May 31;6(22). pii: e00467-18. doi: 10.1128/genomeA.00467-18. Erratum in: Microbiol Resour Announc. 2018 Jul 19;7(2):.


Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor.

Hovingh ES, Mariman R, Solans L, Hijdra D, Hamstra HJ, Jongerius I, van Gent M, Mooi F, Locht C, Pinelli E.

Emerg Microbes Infect. 2018 Mar 21;7(1):39. doi: 10.1038/s41426-018-0039-8.


Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface.

Hovingh ES, van den Broek B, Kuipers B, Pinelli E, Rooijakkers SHM, Jongerius I.

PLoS Pathog. 2017 Jul 24;13(7):e1006531. doi: 10.1371/journal.ppat.1006531. eCollection 2017 Jul.


Longitudinal relationship between fecal culture, fecal quantitative PCR, and milk ELISA in Mycobacterium avium ssp. paratuberculosis-infected cows from low-prevalence dairy herds.

Beaver A, Sweeney RW, Hovingh E, Wolfgang DR, Gröhn YT, Schukken YH.

J Dairy Sci. 2017 Sep;100(9):7507-7521. doi: 10.3168/jds.2017-12928. Epub 2017 Jun 21.


Emerging Bordetella pertussis Strains Induce Enhanced Signaling of Human Pattern Recognition Receptors TLR2, NOD2 and Secretion of IL-10 by Dendritic Cells.

Hovingh ES, van Gent M, Hamstra HJ, Demkes M, Mooi FR, Pinelli E.

PLoS One. 2017 Jan 11;12(1):e0170027. doi: 10.1371/journal.pone.0170027. eCollection 2017.


Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion.

Hovingh ES, van den Broek B, Jongerius I.

Front Microbiol. 2016 Dec 20;7:2004. doi: 10.3389/fmicb.2016.02004. eCollection 2016. Review.


Herd management and social variables associated with bulk tank somatic cell count in dairy herds in the eastern United States.

Schewe RL, Kayitsinga J, Contreras GA, Odom C, Coats WA, Durst P, Hovingh EP, Martinez RO, Mobley R, Moore S, Erskine RJ.

J Dairy Sci. 2015 Nov;98(11):7650-65. doi: 10.3168/jds.2014-8840. Epub 2015 Aug 20.


Molecular detection of the index case of a subclinical Salmonella Kentucky epidemic on a dairy farm.

Haley BJ, Allard M, Brown E, Hovingh E, Karns JS, van Kessel JS.

Epidemiol Infect. 2015 Mar;143(4):682-6. doi: 10.1017/S0950268814001289.


An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model.

Krumm SA, Yan D, Hovingh ES, Evers TJ, Enkirch T, Reddy GP, Sun A, Saindane MT, Arrendale RF, Painter G, Liotta DC, Natchus MG, von Messling V, Plemper RK.

Sci Transl Med. 2014 Apr 16;6(232):232ra52. doi: 10.1126/scitranslmed.3008517.


Mycobacterium avium subsp. paratuberculosis antibody response, fecal shedding, and antibody cross-reactivity to Mycobacterium bovis in M. avium subsp. paratuberculosis-infected cattle herds vaccinated against Johne's disease.

Tewari D, Hovingh E, Linscott R, Martel E, Lawrence J, Wolfgang D, Griswold D.

Clin Vaccine Immunol. 2014 May;21(5):698-703. doi: 10.1128/CVI.00032-14. Epub 2014 Mar 12.


Stochastic modeling of imperfect Salmonella vaccines in an adult dairy herd.

Lu Z, Gröhn YT, Smith RL, Karns JS, Hovingh E, Schukken YH.

Bull Math Biol. 2014 Mar;76(3):541-65. doi: 10.1007/s11538-013-9931-5. Epub 2014 Feb 28.


Regional distribution of two dairy-associated Salmonella enterica serotypes.

Van Kessel JA, Karns JS, Wolfgang DR, Hovingh E.

Foodborne Pathog Dis. 2013 May;10(5):448-52. doi: 10.1089/fpd.2012.1380. Epub 2013 Mar 28.


Granzyme M cannot induce cell death via cleavage of mouse FADD.

de Poot SA, Lai KW, Hovingh ES, Bovenschen N.

Apoptosis. 2013 Apr;18(4):533-4. doi: 10.1007/s10495-013-0810-1. No abstract available.


Dynamics of Salmonella serotype shifts in an endemically infected dairy herd.

Van Kessel JA, Karns JS, Wolfgang DR, Hovingh E, Schukken YH.

Foodborne Pathog Dis. 2012 Apr;9(4):319-24. doi: 10.1089/fpd.2011.1054. Epub 2012 Feb 2.


Molecular epidemiology of Mycobacterium avium subsp. paratuberculosis in a longitudinal study of three dairy herds.

Pradhan AK, Mitchell RM, Kramer AJ, Zurakowski MJ, Fyock TL, Whitlock RH, Smith JM, Hovingh E, Van Kessel JA, Karns JS, Schukken YH.

J Clin Microbiol. 2011 Mar;49(3):893-901. doi: 10.1128/JCM.01107-10. Epub 2011 Jan 5.


Correlation between Herrold egg yolk medium culture and real-time quantitative polymerase chain reaction results for Mycobacterium avium subspecies paratuberculosis in pooled fecal and environmental samples.

Aly SS, Mangold BL, Whitlock RH, Sweeney RW, Anderson RJ, Jiang J, Schukken YH, Hovingh E, Wolfgang D, Van Kessel JA, Karns JS, Lombard JE, Smith JM, Gardner IA.

J Vet Diagn Invest. 2010 Sep;22(5):677-83.


Dynamics of endemic infectious diseases of animal and human importance on three dairy herds in the northeastern United States.

Pradhan AK, Van Kessel JS, Karns JS, Wolfgang DR, Hovingh E, Nelen KA, Smith JM, Whitlock RH, Fyock T, Ladely S, Fedorka-Cray PJ, Schukken YH.

J Dairy Sci. 2009 Apr;92(4):1811-25. doi: 10.3168/jds.2008-1486.


Environmental sampling to predict fecal prevalence of Salmonella in an intensively monitored dairy herd.

Van Kessel JS, Karns JS, Wolfgang DR, Hovingh E, Jayarao BM, Van Tassell CP, Schukken YH.

J Food Prot. 2008 Oct;71(10):1967-73.


Longitudinal study of a clonal, subclinical outbreak of Salmonella enterica subsp. enterica serovar Cerro in a U.S. dairy herd.

Van Kessel JS, Karns JS, Wolfgang DR, Hovingh E, Schukken YH.

Foodborne Pathog Dis. 2007 Winter;4(4):449-61.


Effects of ultraviolet irradiation on chemical and sensory properties of goat milk.

Matak KE, Sumner SS, Duncan SE, Hovingh E, Worobo RW, Hackney CR, Pierson MD.

J Dairy Sci. 2007 Jul;90(7):3178-86.


Failure to detect bovine viral diarrhea virus in necropsied farm-raised white-tailed deer (Odocoileus virginianus) in Pennsylvania.

Brooks JW, Key DW, Hattel AL, Hovingh EP, Peterson R, Shaw DP, Fisher JS.

J Vet Diagn Invest. 2007 May;19(3):298-300.


A mathematical model of the dynamics of Salmonella Cerro infection in a US dairy herd.

Chapagain PP, van Kessel JS, Karns JS, Wolfgang DR, Hovingh E, Nelen KA, Schukken YH, Grohn YT.

Epidemiol Infect. 2008 Feb;136(2):263-72. Epub 2007 Apr 20.


Efficacy of UV light for the reduction of Listeria monocytogenes in goat's milk.

Matak KE, Churey JJ, Worobo RW, Sumner SS, Hovingh E, Hackney CR, Pierson MD.

J Food Prot. 2005 Oct;68(10):2212-6.


Veterinary medical imaging: other considerations in critical thinking.

Dohoo I, Spangler L, Hammell L, Davidson J, Munroe F, Hovingh E.

Can Vet J. 1995 Feb;36(2):71-2. No abstract available.

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