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Items: 1 to 50 of 175

1.

Vaccination with the Conserved Caveolin-1 Binding Motif in Human Immunodeficiency Virus Type 1 Glycoprotein gp41 Delays the Onset of Viral Infection and Provides Partial Protection in Simian/Human Immunodeficiency Virus-Challenged Cynomolgus Macaques.

Hovanessian AG, Soundaramourty C, Benferhat R, Le Grand R, Dereuddre-Bosquet N, Krust B, Estaquier J.

J Virol. 2018 Aug 29;92(18). pii: e00370-18. doi: 10.1128/JVI.00370-18. Print 2018 Sep 15.

2.

Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type.

Krust B, El Khoury D, Nondier I, Soundaramourty C, Hovanessian AG.

BMC Cancer. 2011 Aug 3;11:333. doi: 10.1186/1471-2407-11-333.

3.

Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization.

Hovanessian AG, Soundaramourty C, El Khoury D, Nondier I, Svab J, Krust B.

PLoS One. 2010 Dec 23;5(12):e15787. doi: 10.1371/journal.pone.0015787.

4.

Suppression of tumorigenicity of rhabdoid tumor derived G401 cells by the multivalent HB-19 pseudopeptide that targets surface nucleolin.

Krust B, El Khoury D, Soundaramourty C, Nondier I, Hovanessian AG.

Biochimie. 2011 Mar;93(3):426-33. doi: 10.1016/j.biochi.2010.10.015. Epub 2010 Oct 30.

PMID:
21040752
5.

Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice.

El Khoury D, Destouches D, Lengagne R, Krust B, Hamma-Kourbali Y, Garcette M, Niro S, Kato M, Briand JP, Courty J, Hovanessian AG, Prévost-Blondel A.

BMC Cancer. 2010 Jun 24;10:325. doi: 10.1186/1471-2407-10-325.

6.

The caveolin-1 binding domain of HIV-1 glycoprotein gp41 (CBD1) contains several overlapping neutralizing epitopes.

Benferhat R, Krust B, Rey-Cuillé MA, Hovanessian AG.

Vaccine. 2009 Jun 2;27(27):3620-30. doi: 10.1016/j.vaccine.2009.03.057. Epub 2009 Apr 10.

PMID:
19464543
7.

The cell surface expressed nucleolin is a glycoprotein that triggers calcium entry into mammalian cells.

Losfeld ME, Khoury DE, Mariot P, Carpentier M, Krust B, Briand JP, Mazurier J, Hovanessian AG, Legrand D.

Exp Cell Res. 2009 Jan 15;315(2):357-69. doi: 10.1016/j.yexcr.2008.10.039. Epub 2008 Nov 6.

PMID:
19026635
8.

The CBD1 peptide corresponding to the caveolin-1 binding domain of HIV-1 glycoprotein gp41 elicits neutralizing antibodies in cynomolgus macaques when administered with the tetanus T helper epitope.

Benferhat R, Martinon F, Krust B, Le Grand R, Hovanessian AG.

Mol Immunol. 2009 Feb;46(4):705-12. doi: 10.1016/j.molimm.2008.10.001. Epub 2008 Nov 17.

PMID:
19010547
9.

A novel receptor - ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: interaction between surface nucleolin and bacterial elongation factor Tu.

Barel M, Hovanessian AG, Meibom K, Briand JP, Dupuis M, Charbit A.

BMC Microbiol. 2008 Sep 12;8:145. doi: 10.1186/1471-2180-8-145.

10.

Suppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolin.

Destouches D, El Khoury D, Hamma-Kourbali Y, Krust B, Albanese P, Katsoris P, Guichard G, Briand JP, Courty J, Hovanessian AG.

PLoS One. 2008 Jun 18;3(6):e2518. doi: 10.1371/journal.pone.0002518.

11.

The immunogenic CBD1 peptide corresponding to the caveolin-1 binding domain in HIV-1 envelope gp41 has the capacity to penetrate the cell membrane and bind caveolin-1.

Benferhat R, Sanchez-Martinez S, Nieva JL, Briand JP, Hovanessian AG.

Mol Immunol. 2008 Apr;45(7):1963-75. Epub 2007 Dec 3.

PMID:
18054388
12.

On the discovery of interferon-inducible, double-stranded RNA activated enzymes: the 2'-5'oligoadenylate synthetases and the protein kinase PKR.

Hovanessian AG.

Cytokine Growth Factor Rev. 2007 Oct-Dec;18(5-6):351-61. Epub 2007 Aug 2. Review.

PMID:
17681872
13.
14.

HIV-1 neutralizing antibodies elicited by the candidate CBD1 epitope vaccine react with the conserved caveolin-1 binding motif of viral glycoprotein gp41.

Rey-Cuillé MA, Svab J, Benferhat R, Krust B, Briand JP, Muller S, Hovanessian AG.

J Pharm Pharmacol. 2006 Jun;58(6):759-67.

PMID:
16734977
15.
16.

Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolin.

Said EA, Courty J, Svab J, Delbé J, Krust B, Hovanessian AG.

FEBS J. 2005 Sep;272(18):4646-59.

17.

Regulatory serine residues mediate phosphorylation-dependent and phosphorylation-independent activation of interferon regulatory factor 7.

Caillaud A, Hovanessian AG, Levy DE, Marié IJ.

J Biol Chem. 2005 May 6;280(18):17671-7. Epub 2005 Mar 2.

18.

Efficient synthesis and comparative studies of the arginine and Nomega,Nomega-dimethylarginine forms of the human nucleolin glycine/arginine rich domain.

Zahariev S, Guarnaccia C, Zanuttin F, Pintar A, Esposito G, Maravić G, Krust B, Hovanessian AG, Pongor S.

J Pept Sci. 2005 Jan;11(1):17-28.

PMID:
15635723
19.

The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection.

Hovanessian AG, Briand JP, Said EA, Svab J, Ferris S, Dali H, Muller S, Desgranges C, Krust B.

Immunity. 2004 Nov;21(5):617-27.

20.

Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells.

Legrand D, Vigié K, Said EA, Elass E, Masson M, Slomianny MC, Carpentier M, Briand JP, Mazurier J, Hovanessian AG.

Eur J Biochem. 2004 Jan;271(2):303-17.

21.

Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding.

Caillaud A, Prakash A, Smith E, Masumi A, Hovanessian AG, Levy DE, Marié I.

J Biol Chem. 2002 Dec 20;277(51):49417-21. Epub 2002 Oct 8.

22.

The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor.

Said EA, Krust B, Nisole S, Svab J, Briand JP, Hovanessian AG.

J Biol Chem. 2002 Oct 4;277(40):37492-502. Epub 2002 Jul 29.

23.
24.

Adenovirus infection targets the cellular protein kinase CK2 and RNA-activated protein kinase (PKR) into viral inclusions of the cell nucleus.

Souquere-Besse S, Pichard E, Filhol O, Legrand V, Rosa-Calatrava M, Hovanessian AG, Cochet C, Puvion-Dutilleul F.

Microsc Res Tech. 2002 Mar 15;56(6):465-78.

PMID:
11921349
25.

The anti-HIV pentameric pseudopeptide HB-19 binds the C-terminal end of nucleolin and prevents anchorage of virus particles in the plasma membrane of target cells.

Nisole S, Said EA, Mische C, Prevost MC, Krust B, Bouvet P, Bianco A, Briand JP, Hovanessian AG.

J Biol Chem. 2002 Jun 7;277(23):20877-86. Epub 2002 Mar 27.

26.

The anti-HIV pentameric pseudopeptide HB-19 is preferentially taken up in vivo by lymphoid organs where it forms a complex with nucleolin.

Krust B, Vienet R, Cardona A, Rougeot C, Jacotot E, Callebaut C, Guichard G, Briand JP, Grognet JM, Hovanessian AG, Edelman L.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):14090-5. Epub 2001 Nov 6.

27.

Inhibition of HIV infection by the cytokine midkine.

Callebaut C, Nisole S, Briand JP, Krust B, Hovanessian AG.

Virology. 2001 Mar 15;281(2):248-64.

28.

Characterization of the gene encoding the 100-kDa form of human 2',5' oligoadenylate synthetase.

Rebouillat D, Hovnanian A, David G, Hovanessian AG, Williams BR.

Genomics. 2000 Dec 1;70(2):232-40.

PMID:
11112351
29.

The cell-surface-expressed nucleolin is associated with the actin cytoskeleton.

Hovanessian AG, Puvion-Dutilleul F, Nisole S, Svab J, Perret E, Deng JS, Krust B.

Exp Cell Res. 2000 Dec 15;261(2):312-28.

PMID:
11112338
30.

The HIV-1 gp120 inhibits the binding of adenosine deaminase to CD26 by a mechanism modulated by CD4 and CXCR4 expression.

Blanco J, Valenzuela A, Herrera C, Lluís C, Hovanessian AG, Franco R.

FEBS Lett. 2000 Jul 14;477(1-2):123-8.

31.

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

Bonnet MC, Weil R, Dam E, Hovanessian AG, Meurs EF.

Mol Cell Biol. 2000 Jul;20(13):4532-42.

32.

The HB-19 pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits attachment of T lymophocyte- and macrophage-tropic HIV to permissive cells.

Nisole S, Krust B, Dam E, Bianco A, Seddiki N, Loaec S, Callebaut C, Guichard G, Muller S, Briand JP, Hovanessian AG.

AIDS Res Hum Retroviruses. 2000 Feb 10;16(3):237-49.

PMID:
10710212
33.

The anti-HIV pseudopeptide HB-19 forms a complex with the cell-surface-expressed nucleolin independent of heparan sulfate proteoglycans.

Nisole S, Krust B, Callebaut C, Guichard G, Muller S, Briand JP, Hovanessian AG.

J Biol Chem. 1999 Sep 24;274(39):27875-84.

34.

Colocalization within the nucleolus of two highly related IFN-induced human nuclear phosphoproteins with nucleolin.

Welsh GI, Kadereit S, Coccia EM, Hovanessian AG, Meurs EF.

Exp Cell Res. 1999 Jul 10;250(1):62-74.

PMID:
10388521
35.

The human 2',5'-oligoadenylate synthetase family: interferon-induced proteins with unique enzymatic properties.

Rebouillat D, Hovanessian AG.

J Interferon Cytokine Res. 1999 Apr;19(4):295-308. Review.

PMID:
10334380
37.

The human 2',5'-oligoadenylate synthetase-like gene (OASL) encoding the interferon-induced 56-kDa protein maps to chromosome 12q24.2 in the proximity of the 2',5'-OAS locus.

Hovnanian A, Rebouillat D, Levy ER, Mattei MG, Hovanessian AG.

Genomics. 1999 Mar 15;56(3):362-3. No abstract available.

PMID:
10087211
38.

The V3 loop-mimicking pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits HIV infection in primary macrophage cultures.

Seddiki N, Nisole S, Krust B, Callebaut C, Guichard G, Muller S, Briand JP, Hovanessian AG.

AIDS Res Hum Retroviruses. 1999 Mar 1;15(4):381-90.

PMID:
10082122
39.
41.

The human 2',5'-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40-kDa forms.

Hovnanian A, Rebouillat D, Mattei MG, Levy ER, Marié I, Monaco AP, Hovanessian AG.

Genomics. 1998 Sep 15;52(3):267-77.

PMID:
9790745
42.

Dipeptidyl-peptidase IV-beta--further characterization and comparison to dipeptidyl-peptidase IV activity of CD26.

Blanco J, Nguyen C, Callebaut C, Jacotot E, Krust B, Mazaleyrat JP, Wakselman M, Hovanessian AG.

Eur J Biochem. 1998 Sep 1;256(2):369-78.

43.

Identification of V3 loop-binding proteins as potential receptors implicated in the binding of HIV particles to CD4(+) cells.

Callebaut C, Blanco J, Benkirane N, Krust B, Jacotot E, Guichard G, Seddiki N, Svab J, Dam E, Muller S, Briand JP, Hovanessian AG.

J Biol Chem. 1998 Aug 21;273(34):21988-97.

44.

Increased rate of HIV-1 entry and its cytopathic effect in CD4+/CXCR4+ T cells expressing relatively high levels of CD26.

Callebaut C, Jacotot E, Blanco J, Krust B, Hovanessian AG.

Exp Cell Res. 1998 Jun 15;241(2):352-62.

PMID:
9637777
45.

Specific and irreversible cyclopeptide inhibitors of dipeptidyl peptidase IV activity of the T-cell activation antigen CD26.

Nguyen C, Blanco J, Mazaleyrat JP, Krust B, Callebaut C, Jacotot E, Hovanessian AG, Wakselman M.

J Med Chem. 1998 Jun 4;41(12):2100-10.

PMID:
9622551
46.

Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease.

Rey-Cuillé MA, Berthier JL, Bomsel-Demontoy MC, Chaduc Y, Montagnier L, Hovanessian AG, Chakrabarti LA.

J Virol. 1998 May;72(5):3872-86.

47.

Ultrastructural localization of interferon-inducible double-stranded RNA-activated enzymes in human cells.

Besse S, Rebouillat D, Marie I, Puvion-Dutilleul F, Hovanessian AG.

Exp Cell Res. 1998 Mar 15;239(2):379-92.

PMID:
9521856
48.

69-kDa and 100-kDa isoforms of interferon-induced (2'-5')oligoadenylate synthetase exhibit differential catalytic parameters.

Marié I, Blanco J, Rebouillat D, Hovanessian AG.

Eur J Biochem. 1997 Sep 1;248(2):558-66.

49.
50.

Dipeptidyl-peptidase IV secreted by Aspergillus fumigatus, a fungus pathogenic to humans.

Beauvais A, Monod M, Wyniger J, Debeaupuis JP, Grouzmann E, Brakch N, Svab J, Hovanessian AG, Latgé JP.

Infect Immun. 1997 Aug;65(8):3042-7.

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