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Items: 1 to 50 of 57

1.

Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system.

Haaker MW, Kruitwagen HS, Vaandrager AB, Houweling M, Penning LC, Molenaar MR, van Wolferen ME, Oosterhoff LA, Spee B, Helms JB.

J Vet Intern Med. 2020 Jan;34(1):132-138. doi: 10.1111/jvim.15670. Epub 2019 Dec 12.

2.

Schistosoma mansoni does not and cannot oxidise fatty acids, but these are used for biosynthetic purposes instead.

Bexkens ML, Mebius MM, Houweling M, Brouwers JF, Tielens AGM, van Hellemond JJ.

Int J Parasitol. 2019 Jul;49(8):647-656. doi: 10.1016/j.ijpara.2019.03.005. Epub 2019 Jun 3.

PMID:
31170410
3.

The TICking clock of EGFR therapy resistance in glioblastoma: Target Independence or target Compensation.

Saleem H, Kulsoom Abdul U, Küçükosmanoglu A, Houweling M, Cornelissen FMG, Heiland DH, Hegi ME, Kouwenhoven MCM, Bailey D, Würdinger T, Westerman BA.

Drug Resist Updat. 2019 Mar;43:29-37. doi: 10.1016/j.drup.2019.04.002. Epub 2019 Apr 22.

4.

Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity.

Weigand KM, Schirris TJJ, Houweling M, van den Heuvel JJMW, Koenderink JB, Dankers ACA, Russel FGM, Greupink R.

Toxicol In Vitro. 2019 Apr;56:52-61. doi: 10.1016/j.tiv.2019.01.003. Epub 2019 Jan 9.

5.

WINDOW consortium: A path towards increased therapy efficacy against glioblastoma.

Abdul KU, Houweling M, Svensson F, Narayan RS, Cornelissen FMG, Küçükosmanoglu A, Metzakopian E, Watts C, Bailey D, Wurdinger T, Westerman BA.

Drug Resist Updat. 2018 Sep;40:17-24. doi: 10.1016/j.drup.2018.10.001. Epub 2018 Oct 30. Review.

PMID:
30439622
6.

Lysosome-mediated degradation of a distinct pool of lipid droplets during hepatic stellate cell activation.

Tuohetahuntila M, Molenaar MR, Spee B, Brouwers JF, Wubbolts R, Houweling M, Yan C, Du H, VanderVen BC, Vaandrager AB, Helms JB.

J Biol Chem. 2017 Jul 28;292(30):12436-12448. doi: 10.1074/jbc.M117.778472. Epub 2017 Jun 14.

7.

Farnesoid X Receptor Activation Promotes Hepatic Amino Acid Catabolism and Ammonium Clearance in Mice.

Massafra V, Milona A, Vos HR, Ramos RJJ, Gerrits J, Willemsen ECL, Ramos Pittol JM, Ijssennagger N, Houweling M, Prinsen HCMT, Verhoeven-Duif NM, Burgering BMT, van Mil SWC.

Gastroenterology. 2017 May;152(6):1462-1476.e10. doi: 10.1053/j.gastro.2017.01.014. Epub 2017 Jan 25.

8.

Hepatic stellate cells retain the capacity to synthesize retinyl esters and to store neutral lipids in small lipid droplets in the absence of LRAT.

Ajat M, Molenaar M, Brouwers JFHM, Vaandrager AB, Houweling M, Helms JB.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Feb;1862(2):176-187. doi: 10.1016/j.bbalip.2016.10.013. Epub 2016 Nov 1.

PMID:
27815220
9.

ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells.

Tuohetahuntila M, Molenaar MR, Spee B, Brouwers JF, Houweling M, Vaandrager AB, Helms JB.

J Lipid Res. 2016 Jul;57(7):1162-74. doi: 10.1194/jlr.M066415. Epub 2016 May 14.

10.

Effects of a single glucocorticoid injection on propylene glycol-treated cows with clinical ketosis.

van der Drift SG, Houweling M, Bouman M, Koets AP, Tielens AG, Nielen M, Jorritsma R.

Vet J. 2015 May;204(2):144-9. doi: 10.1016/j.tvjl.2015.01.016. Epub 2015 Jan 26.

PMID:
25841896
11.

Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells.

Tuohetahuntila M, Spee B, Kruitwagen HS, Wubbolts R, Brouwers JF, van de Lest CH, Molenaar MR, Houweling M, Helms JB, Vaandrager AB.

Biochim Biophys Acta. 2015 Feb;1851(2):220-30. doi: 10.1016/j.bbalip.2014.12.003. Epub 2014 Dec 9.

PMID:
25500141
12.

In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.

Haberkant P, Raijmakers R, Wildwater M, Sachsenheimer T, Brügger B, Maeda K, Houweling M, Gavin AC, Schultz C, van Meer G, Heck AJ, Holthuis JC.

Angew Chem Int Ed Engl. 2013 Apr 2;52(14):4033-8. doi: 10.1002/anie.201210178. Epub 2013 Feb 28. No abstract available.

PMID:
23450850
13.

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.

Smolders LA, Meij BP, Onis D, Riemers FM, Bergknut N, Wubbolts R, Grinwis GC, Houweling M, Groot Koerkamp MJ, van Leenen D, Holstege FC, Hazewinkel HA, Creemers LB, Penning LC, Tryfonidou MA.

Arthritis Res Ther. 2013 Jan 29;15(1):R23. doi: 10.1186/ar4157.

14.

Effects of β-hydroxybutyrate and isoproterenol on lipolysis in isolated adipocytes from periparturient dairy cows and cows with clinical ketosis.

van der Drift SG, Everts RR, Houweling M, van Leengoed LA, Stegeman JA, Tielens AG, Jorritsma R.

Res Vet Sci. 2013 Jun;94(3):433-9. doi: 10.1016/j.rvsc.2012.11.009. Epub 2012 Dec 19.

PMID:
23256919
15.

Protein and fat mobilization and associations with serum β-hydroxybutyrate concentrations in dairy cows.

van der Drift SGA, Houweling M, Schonewille JT, Tielens AGM, Jorritsma R.

J Dairy Sci. 2012 Sep;95(9):4911-4920. doi: 10.3168/jds.2011-4771.

16.

Technical note: quantification of plasma 1- and 3-methylhistidine in dairy cows by high-performance liquid chromatography-tandem mass spectrometry.

Houweling M, van der Drift SG, Jorritsma R, Tielens AG.

J Dairy Sci. 2012 Jun;95(6):3125-30. doi: 10.3168/jds.2011-4769.

17.

Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of hepatic stellate cells during activation.

Testerink N, Ajat M, Houweling M, Brouwers JF, Pully VV, van Manen HJ, Otto C, Helms JB, Vaandrager AB.

PLoS One. 2012;7(4):e34945. doi: 10.1371/journal.pone.0034945. Epub 2012 Apr 20.

18.

The yeast acyltransferase Sct1p regulates fatty acid desaturation by competing with the desaturase Ole1p.

De Smet CH, Vittone E, Scherer M, Houweling M, Liebisch G, Brouwers JF, de Kroon AI.

Mol Biol Cell. 2012 Apr;23(7):1146-56. doi: 10.1091/mbc.E11-07-0624. Epub 2012 Feb 9.

19.

Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex.

Testerink N, van der Sanden MH, Houweling M, Helms JB, Vaandrager AB.

J Lipid Res. 2009 Nov;50(11):2182-92. doi: 10.1194/jlr.M800660-JLR200. Epub 2009 May 20.

20.

Iliopsoas impingement after total hip replacement: the results of non-operative management, tenotomy or acetabular revision.

Dora C, Houweling M, Koch P, Sierra RJ.

J Bone Joint Surg Br. 2007 Aug;89(8):1031-5.

PMID:
17785740
21.

The CDP-ethanolamine pathway and phosphatidylserine decarboxylation generate different phosphatidylethanolamine molecular species.

Bleijerveld OB, Brouwers JF, Vaandrager AB, Helms JB, Houweling M.

J Biol Chem. 2007 Sep 28;282(39):28362-72. Epub 2007 Aug 2.

22.

Metabolipidomics: profiling metabolism of glycerophospholipid species by stable isotopic precursors and tandem mass spectrometry.

Bleijerveld OB, Houweling M, Thomas MJ, Cui Z.

Anal Biochem. 2006 May 1;352(1):1-14. Epub 2006 Mar 10. Review. No abstract available.

PMID:
16564484
23.

Luteinizing hormone inhibits Fas-induced apoptosis in ovarian surface epithelial cell lines.

Slot KA, de Boer-Brouwer M, Houweling M, Vaandrager AB, Dorrington JH, Teerds KJ.

J Endocrinol. 2006 Feb;188(2):227-39.

PMID:
16461549
24.

Effects of a single dose of dexamethasone-21-isonicotinate on the metabolism of heifers in early lactation.

Jorritsma R, Thanasak J, Houweling M, Noordhuizen JP, Müller KE.

Vet Rec. 2004 Oct 23;155(17):521-3.

PMID:
15551926
25.

Hexadecylphosphocholine causes rapid cell death in canine mammary tumour cells.

Duijsings D, Houweling M, Vaandrager AB, Mol JA, Teerds KJ.

Eur J Pharmacol. 2004 Oct 19;502(3):185-93.

PMID:
15476744
27.

Inhibition of phosphatidylcholine synthesis is not the primary pathway in hexadecylphosphocholine-induced apoptosis.

van der Sanden MH, Houweling M, Duijsings D, Vaandrager AB, van Golde LM.

Biochim Biophys Acta. 2004 Mar 22;1636(2-3):99-107. Review.

PMID:
15164757
28.
29.

Phosphatidylcholine and cell death.

Cui Z, Houweling M.

Biochim Biophys Acta. 2002 Dec 30;1585(2-3):87-96. Review.

PMID:
12531541
31.

Effect of ceramides on phospholipid biosynthesis and its implication for apoptosis.

Vaandrager AB, Houweling M.

Subcell Biochem. 2002;36:207-27. Review. No abstract available.

PMID:
12037983
33.

8-year survivorship analysis and subjective results of 687 primary Balgrist hip sockets.

Echtler B, Jacob HA, Houweling M, Hersche O.

Acta Orthop Belg. 1999 Sep;65(3):346-56.

PMID:
10546357
34.

Cloning and expression of CTP:phosphoethanolamine cytidylyltransferase cDNA from rat liver.

Bladergroen BA, Houweling M, Geelen MJ, van Golde LM.

Biochem J. 1999 Oct 1;343 Pt 1:107-14.

35.

Inhibition of phosphatidylcholine and phosphatidylethanolamine biosynthesis in rat-2 fibroblasts by cell-permeable ceramides.

Bladergroen BA, Bussière M, Klein W, Geelen MJ, Van Golde LM, Houweling M.

Eur J Biochem. 1999 Aug;264(1):152-60.

36.
37.

A genetic defect in phosphatidylcholine biosynthesis triggers apoptosis in Chinese hamster ovary cells.

Cui Z, Houweling M, Chen MH, Record M, Chap H, Vance DE, Tercé F.

J Biol Chem. 1996 Jun 21;271(25):14668-71.

38.

Phosphatidylethanolamine methylation and hepatoma cell growth.

Vance DE, Houweling M, Lee M, Cui Z.

Anticancer Res. 1996 May-Jun;16(3B):1413-6. Review.

PMID:
8694509
39.

CTP: phosphocholine cytidylyltransferase is both a nuclear and cytoplasmic protein in primary hepatocytes.

Houweling M, Cui Z, Anfuso CD, Bussière M, Chen MH, Vance DE.

Eur J Cell Biol. 1996 Jan;69(1):55-63.

PMID:
8825024
41.
43.
44.

Dephosphorylation of CTP-phosphocholine cytidylyltransferase is not required for binding to membranes.

Houweling M, Jamil H, Hatch GM, Vance DE.

J Biol Chem. 1994 Mar 11;269(10):7544-51.

45.

Phospholipid-transfer proteins and their mRNAs in developing rat lung and in alveolar type-II cells.

Batenburg JJ, Ossendorp BC, Snoek GT, Wirtz KW, Houweling M, Elfring RH.

Biochem J. 1994 Feb 15;298 ( Pt 1):223-9.

46.

Evidence that CTP:choline-phosphate cytidylyltransferase is regulated at a pretranslational level in rat liver after partial hepatectomy.

Houweling M, Tijburg LB, Vaartjes WJ, Batenburg JJ, Kalmar GB, Cornell RB, Van Golde LM.

Eur J Biochem. 1993 Jun 15;214(3):927-33.

47.
49.

Phosphatidylcholine metabolism in rat liver after partial hepatectomy. Evidence for increased activity and amount of CTP:phosphocholine cytidylyltransferase.

Houweling M, Tijburg LB, Jamil H, Vance DE, Nyathi CB, Vaartjes WJ, van Golde LM.

Biochem J. 1991 Sep 1;278 ( Pt 2):347-51.

50.

Acute effects of interleukin 1 alpha and 6 on intermediary metabolism in freshly isolated rat hepatocytes.

Vaartjes WJ, de Haas CG, Houweling M.

Biochem Biophys Res Commun. 1990 Jun 15;169(2):623-8.

PMID:
2357222

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