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Items: 1 to 50 of 252

1.

The Practice-Based Implementation (PBI) Network: Technology (Tech) into Care pilot.

Pratt KM, Branch LZ, Houston JB.

Transl Behav Med. 2019 Nov 28. pii: ibz174. doi: 10.1093/tbm/ibz174. [Epub ahead of print]

PMID:
31781757
2.

Disaster journalism: fostering citizen and community disaster mitigation, preparedness, response, recovery, and resilience across the disaster cycle.

Houston JB, Schraedley MK, Worley ME, Reed K, Saidi J.

Disasters. 2019 Jul;43(3):591-611. doi: 10.1111/disa.12352. Epub 2019 Apr 16.

PMID:
30990926
3.

Disaster Communication, Posttraumatic Stress, and Posttraumatic Growth following Hurricane Matthew.

Spialek ML, Houston JB, Worley KC.

J Health Commun. 2019;24(1):65-74. doi: 10.1080/10810730.2019.1574319. Epub 2019 Feb 4.

PMID:
30714877
4.

Use of Segregated Hepatocyte Scaling Factors and Cross-Species Relationships to Resolve Clearance Dependence in the Prediction of Human Hepatic Clearance.

Hallifax D, Houston JB.

Drug Metab Dispos. 2019 Mar;47(3):320-327. doi: 10.1124/dmd.118.085191. Epub 2019 Jan 4.

PMID:
30610004
5.

Hepatic Organic Anion Transporting Polypeptide-Mediated Clearance in the Beagle Dog: Assessing In Vitro-In Vivo Relationships and Applying Cross-Species Empirical Scaling Factors to Improve Prediction of Human Clearance.

Matsunaga N, Ufuk A, Morse BL, Bedwell DW, Bao J, Mohutsky MA, Hillgren KM, Hall SD, Houston JB, Galetin A.

Drug Metab Dispos. 2019 Mar;47(3):215-226. doi: 10.1124/dmd.118.084194. Epub 2018 Dec 28.

PMID:
30593544
6.

Interdisciplinary Research as an Iterative Process to Build Disaster Systems Knowledge.

Subedi J, Houston JB, Sherman-Morris K.

Risk Anal. 2018 Nov 22. doi: 10.1111/risa.13244. [Epub ahead of print]

PMID:
30466154
7.

Theoretical Matters: On the Need for Hazard and Disaster Theory Developed Through Interdisciplinary Research and Collaboration.

Sherman-Morris K, Houston JB, Subedi J.

Risk Anal. 2018 Oct 25. doi: 10.1111/risa.13223. [Epub ahead of print]

PMID:
30368854
8.

Predicting Human Clearance of Organic Anion Transporting Polypeptide Substrates Using Cynomolgus Monkey: In Vitro-In Vivo Scaling of Hepatic Uptake Clearance.

De Bruyn T, Ufuk A, Cantrill C, Kosa RE, Bi YA, Niosi M, Modi S, Rodrigues AD, Tremaine LM, Varma MVS, Galetin A, Houston JB.

Drug Metab Dispos. 2018 Jul;46(7):989-1000. doi: 10.1124/dmd.118.081315. Epub 2018 May 2.

PMID:
29720472
9.

In Vitro-In Vivo Extrapolation of OATP1B-Mediated Drug-Drug Interactions in Cynomolgus Monkey.

Ufuk A, Kosa RE, Gao H, Bi YA, Modi S, Gates D, Rodrigues AD, Tremaine LM, Varma MVS, Houston JB, Galetin A.

J Pharmacol Exp Ther. 2018 Jun;365(3):688-699. doi: 10.1124/jpet.118.247767. Epub 2018 Apr 11.

PMID:
29643253
10.

Simultaneous Assessment In Vitro of Transporter and Metabolic Processes in Hepatic Drug Clearance: Use of a Media Loss Approach.

Harrison J, De Bruyn T, Darwich AS, Houston JB.

Drug Metab Dispos. 2018 Apr;46(4):405-414. doi: 10.1124/dmd.117.079590. Epub 2018 Feb 8.

PMID:
29439129
11.

Importance of the Unstirred Water Layer and Hepatocyte Membrane Integrity In Vitro for Quantification of Intrinsic Metabolic Clearance.

Wood FL, Houston JB, Hallifax D.

Drug Metab Dispos. 2018 Mar;46(3):268-278. doi: 10.1124/dmd.117.078949. Epub 2017 Dec 12.

PMID:
29233818
12.

Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology.

Wood FL, Houston JB, Hallifax D.

Drug Metab Dispos. 2017 Nov;45(11):1178-1188. doi: 10.1124/dmd.117.077040. Epub 2017 Sep 8. Erratum in: Drug Metab Dispos. 2017 Dec;45(12 ):1239.

PMID:
28887366
13.

Incorporation of lysosomal sequestration in the mechanistic model for prediction of tissue distribution of basic drugs.

Assmus F, Houston JB, Galetin A.

Eur J Pharm Sci. 2017 Nov 15;109:419-430. doi: 10.1016/j.ejps.2017.08.014. Epub 2017 Aug 18.

PMID:
28823852
14.

Understanding the Interplay Between Uptake and Efflux Transporters Within In Vitro Systems in Defining Hepatocellular Drug Concentrations.

Cantrill C, Houston JB.

J Pharm Sci. 2017 Sep;106(9):2815-2825. doi: 10.1016/j.xphs.2017.04.056. Epub 2017 May 3.

PMID:
28478131
15.

In Vitro and in Silico Tools To Assess Extent of Cellular Uptake and Lysosomal Sequestration of Respiratory Drugs in Human Alveolar Macrophages.

Ufuk A, Assmus F, Francis L, Plumb J, Damian V, Gertz M, Houston JB, Galetin A.

Mol Pharm. 2017 Apr 3;14(4):1033-1046. doi: 10.1021/acs.molpharmaceut.6b00908. Epub 2017 Mar 20.

PMID:
28252969
16.

Randomized controlled trial of the Resilience and Coping Intervention (RCI) with undergraduate university students.

Houston JB, First J, Spialek ML, Sorenson ME, Mills-Sandoval T, Lockett M, First NL, Nitiéma P, Allen SF, Pfefferbaum B.

J Am Coll Health. 2017 Jan;65(1):1-9. doi: 10.1080/07448481.2016.1227826. Epub 2016 Aug 25.

PMID:
27559857
17.

Effects of Displacement in Children Exposed to Disasters.

Pfefferbaum B, Jacobs AK, Van Horn RL, Houston JB.

Curr Psychiatry Rep. 2016 Aug;18(8):71. doi: 10.1007/s11920-016-0714-1. Review.

PMID:
27287465
18.

Public Disaster Communication and Child and Family Disaster Mental Health: a Review of Theoretical Frameworks and Empirical Evidence.

Houston JB, First J, Spialek ML, Sorenson ME, Koch M.

Curr Psychiatry Rep. 2016 Jun;18(6):54. doi: 10.1007/s11920-016-0690-5. Review.

PMID:
27086315
19.

Reactions of Oklahoma City bombing survivors to media coverage of the September 11, 2001, attacks.

Pfefferbaum B, Nitiéma P, Pfefferbaum RL, Houston JB, Tucker P, Jeon-Slaughter H, North CS.

Compr Psychiatry. 2016 Feb;65:70-8. doi: 10.1016/j.comppsych.2015.09.010. Epub 2015 Sep 25.

PMID:
26773993
20.

2011 Joplin, Missouri Tornado Experience, Mental Health Reactions, and Service Utilization: Cross-Sectional Assessments at Approximately 6 Months and 2.5 Years Post-Event.

Houston JB, Spialek ML, Stevens J, First J, Mieseler VL, Pfefferbaum B.

PLoS Curr. 2015 Oct 26;7. pii: ecurrents.dis.18ca227647291525ce3415bec1406aa5. doi: 10.1371/currents.dis.18ca227647291525ce3415bec1406aa5.

21.

In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383.

Ufuk A, Somers G, Houston JB, Galetin A.

Pharm Res. 2015 Dec;32(12):3937-51. doi: 10.1007/s11095-015-1753-8. Epub 2015 Jul 30.

22.

Coverage of Posttraumatic Stress Disorder in the New York Times, 1950-2012.

Houston JB, Spialek ML, Perreault MF.

J Health Commun. 2016;21(2):240-8. doi: 10.1080/10810730.2015.1058441. Epub 2015 Dec 30.

PMID:
26166398
23.

Children's disaster reactions: the influence of exposure and personal characteristics.

Pfefferbaum B, Jacobs AK, Griffin N, Houston JB.

Curr Psychiatry Rep. 2015 Jul;17(7):56. doi: 10.1007/s11920-015-0598-5. Review.

PMID:
25980513
24.

Children's disaster reactions: the influence of family and social factors.

Pfefferbaum B, Jacobs AK, Houston JB, Griffin N.

Curr Psychiatry Rep. 2015 Jul;17(7):57. doi: 10.1007/s11920-015-0597-6. Review.

PMID:
25980512
25.

Social media and disasters: a functional framework for social media use in disaster planning, response, and research.

Houston JB, Hawthorne J, Perreault MF, Park EH, Goldstein Hode M, Halliwell MR, Turner McGowen SE, Davis R, Vaid S, McElderry JA, Griffith SA.

Disasters. 2015 Jan;39(1):1-22. doi: 10.1111/disa.12092. Epub 2014 Sep 22. Review.

PMID:
25243593
26.

Hepatic, intestinal, renal, and plasma hydrolysis of prodrugs in human, cynomolgus monkey, dog, and rat: implications for in vitro-in vivo extrapolation of clearance of prodrugs.

Nishimuta H, Houston JB, Galetin A.

Drug Metab Dispos. 2014 Sep;42(9):1522-31. doi: 10.1124/dmd.114.057372. Epub 2014 Jul 3.

PMID:
24994071
27.

Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition.

Smith D, Artursson P, Avdeef A, Di L, Ecker GF, Faller B, Houston JB, Kansy M, Kerns EH, Krämer SD, Lennernäs H, van de Waterbeemd H, Sugano K, Testa B.

Mol Pharm. 2014 Jun 2;11(6):1727-38. doi: 10.1021/mp400713v. Epub 2014 May 6. Review.

PMID:
24724562
28.

Reduced physiologically-based pharmacokinetic model of repaglinide: impact of OATP1B1 and CYP2C8 genotype and source of in vitro data on the prediction of drug-drug interaction risk.

Gertz M, Tsamandouras N, Säll C, Houston JB, Galetin A.

Pharm Res. 2014 Sep;31(9):2367-82. doi: 10.1007/s11095-014-1333-3. Epub 2014 Mar 13.

PMID:
24623479
29.

Children of National Guard troops: a pilot study of deployment, patriotism, and media coverage.

Pfefferbaum B, Jeon-Slaughter H, Jacobs AK, Houston JB.

Int J Emerg Ment Health. 2013;15(2):129-37.

PMID:
24558700
30.

Building community resilience to disasters through a community-based intervention: CART applications.

Pfefferbaum RL, Pfefferbaum B, Van Horn RL, Neas BR, Houston JB.

J Emerg Manag. 2013 Mar-Apr;11(2):151-9.

PMID:
24180095
31.

Prediction of human pharmacokinetics in 2013 and beyond.

Houston JB.

Drug Metab Dispos. 2013 Dec;41(12):1973-4. doi: 10.1124/dmd.113.055376. Epub 2013 Oct 15.

PMID:
24130368
32.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG.

Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Review.

33.

Application of a physiologically based pharmacokinetic model to assess propofol hepatic and renal glucuronidation in isolation: utility of in vitro and in vivo data.

Gill KL, Gertz M, Houston JB, Galetin A.

Drug Metab Dispos. 2013 Apr;41(4):744-53. doi: 10.1124/dmd.112.050294. Epub 2013 Jan 9.

34.

Disaster Research Team Building: A Case Study of a Web-based Disaster Research Training Program.

Beaton RD, Johnson LC, Maida CA, Houston JB, Pfefferbaum B.

Traumatology (Tallahass Fla). 2012 Nov 19;18(4):86-91. Epub 2012 Jun 13.

35.

Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential.

Gertz M, Cartwright CM, Hobbs MJ, Kenworthy KE, Rowland M, Houston JB, Galetin A.

Pharm Res. 2013 Mar;30(3):761-80. doi: 10.1007/s11095-012-0918-y. Epub 2012 Nov 22.

PMID:
23179780
36.

Evaluation of hepatic clearance prediction using in vitro data: emphasis on fraction unbound in plasma and drug ionisation using a database of 107 drugs.

Hallifax D, Houston JB.

J Pharm Sci. 2012 Aug;101(8):2645-52. doi: 10.1002/jps.23202. Epub 2012 Jun 14.

PMID:
22700322
37.

Use of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes.

Ménochet K, Kenworthy KE, Houston JB, Galetin A.

Drug Metab Dispos. 2012 Sep;40(9):1744-56. doi: 10.1124/dmd.112.046193. Epub 2012 Jun 4.

38.

Progress curve mechanistic modeling approach for assessing time-dependent inhibition of CYP3A4.

Burt HJ, Pertinez H, Säll C, Collins C, Hyland R, Houston JB, Galetin A.

Drug Metab Dispos. 2012 Sep;40(9):1658-67. doi: 10.1124/dmd.112.046078. Epub 2012 May 23.

PMID:
22621802
39.

Utility of drug depletion-time profiles in isolated hepatocytes for accessing hepatic uptake clearance: identifying rate-limiting steps and role of passive processes.

Jigorel E, Houston JB.

Drug Metab Dispos. 2012 Aug;40(8):1596-602. doi: 10.1124/dmd.112.045732. Epub 2012 May 16.

PMID:
22593038
40.

Evidence-based approach to assess passive diffusion and carrier-mediated drug transport.

Di L, Artursson P, Avdeef A, Ecker GF, Faller B, Fischer H, Houston JB, Kansy M, Kerns EH, Krämer SD, Lennernäs H, Sugano K.

Drug Discov Today. 2012 Aug;17(15-16):905-12. doi: 10.1016/j.drudis.2012.03.015. Epub 2012 Apr 4. Review.

PMID:
22507594
41.

A comprehensive assessment of repaglinide metabolic pathways: impact of choice of in vitro system and relative enzyme contribution to in vitro clearance.

Säll C, Houston JB, Galetin A.

Drug Metab Dispos. 2012 Jul;40(7):1279-89. doi: 10.1124/dmd.112.045286. Epub 2012 Mar 26.

PMID:
22451699
42.

Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS.

Drug Metab Dispos. 2012 May;40(5):1007-17. doi: 10.1124/dmd.111.042994. Epub 2012 Feb 16.

PMID:
22344703
43.
44.

Evaluation of the novel in vitro systems for hepatic drug clearance and assessment of their predictive utility.

Houston JB, Rowland-Yeo K, Zanelli U.

Toxicol In Vitro. 2012 Dec;26(8):1265-71. doi: 10.1016/j.tiv.2011.12.016. Epub 2012 Jan 8.

PMID:
22244922
45.

Clearance-dependent underprediction of in vivo intrinsic clearance from human hepatocytes: comparison with permeabilities from artificial membrane (PAMPA) assay, in silico and caco-2 assay, for 65 drugs.

Hallifax D, Turlizzi E, Zanelli U, Houston JB.

Eur J Pharm Sci. 2012 Apr 11;45(5):570-4. doi: 10.1016/j.ejps.2011.12.010. Epub 2011 Dec 24.

PMID:
22214813
46.

Incident-related television viewing and psychiatric disorders in Oklahoma City bombing survivors.

Pfefferbaum B, North CS, Pfefferbaum RL, Jeon-Slaughter H, Houston JB, Regens JL.

Int J Emerg Ment Health. 2012;14(4):247-55.

PMID:
23980489
47.

Perception of change and burden in children of national guard troops deployed as part of the global war on terror.

Pfefferbaum B, Houston JB, Allen SF.

Int J Emerg Ment Health. 2012;14(3):189-96.

PMID:
23894799
48.

Simultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic model.

Ménochet K, Kenworthy KE, Houston JB, Galetin A.

J Pharmacol Exp Ther. 2012 Apr;341(1):2-15. doi: 10.1124/jpet.111.187112. Epub 2011 Dec 21.

49.

Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.

Zanelli U, Caradonna NP, Hallifax D, Turlizzi E, Houston JB.

Drug Metab Dispos. 2012 Jan;40(1):104-10. doi: 10.1124/dmd.111.042309. Epub 2011 Oct 13.

PMID:
21998403
50.

Predictive utility of in vitro rifampin induction data generated in fresh and cryopreserved human hepatocytes, Fa2N-4, and HepaRG cells.

Templeton IE, Houston JB, Galetin A.

Drug Metab Dispos. 2011 Oct;39(10):1921-9. doi: 10.1124/dmd.111.040824. Epub 2011 Jul 19.

PMID:
21771933

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