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Items: 13

1.

Exercise Pulmonary Hypertension Predicts Clinical Outcomes in Patients With Dyspnea on Effort.

Ho JE, Zern EK, Lau ES, Wooster L, Bailey CS, Cunningham T, Eisman AS, Hardin KM, Farrell R, Sbarbaro JA, Schoenike MW, Houstis NE, Baggish AL, Shah RV, Nayor M, Malhotra R, Lewis GD.

J Am Coll Cardiol. 2020 Jan 7;75(1):17-26. doi: 10.1016/j.jacc.2019.10.048.

PMID:
31918830
2.

The Upsurge in Exercise Hemodynamic Measurements in Heart Failure With Preserved Ejection Fraction.

Lewis GD, Houstis NE.

JACC Heart Fail. 2019 Apr;7(4):333-335. doi: 10.1016/j.jchf.2019.02.003. No abstract available.

PMID:
30922509
3.

Activin type II receptor signaling in cardiac aging and heart failure.

Roh JD, Hobson R, Chaudhari V, Quintero P, Yeri A, Benson M, Xiao C, Zlotoff D, Bezzerides V, Houstis N, Platt C, Damilano F, Lindman BR, Elmariah S, Biersmith M, Lee SJ, Seidman CE, Seidman JG, Gerszten RE, Lach-Trifilieff E, Glass DJ, Rosenzweig A.

Sci Transl Med. 2019 Mar 6;11(482). pii: eaau8680. doi: 10.1126/scitranslmed.aau8680.

PMID:
30842316
4.

IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism.

Regué L, Ji F, Flicker D, Kramer D, Pierce W, Davidoff T, Widrick JJ, Houstis N, Minichiello L, Dai N, Avruch J.

Mol Cell Biol. 2019 Mar 19;39(7). pii: e00528-18. doi: 10.1128/MCB.00528-18. Print 2019 Apr 1.

5.

Cardiac macrophages promote diastolic dysfunction.

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M.

J Exp Med. 2018 Feb 5;215(2):423-440. doi: 10.1084/jem.20171274. Epub 2018 Jan 16.

6.

Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Diagnosing and Ranking Its Causes Using Personalized O2 Pathway Analysis.

Houstis NE, Eisman AS, Pappagianopoulos PP, Wooster L, Bailey CS, Wagner PD, Lewis GD.

Circulation. 2018 Jan 9;137(2):148-161. doi: 10.1161/CIRCULATIONAHA.117.029058. Epub 2017 Oct 9.

7.

Why Don't We Have Proven Treatments for HFpEF?

Roh J, Houstis N, Rosenzweig A.

Circ Res. 2017 Apr 14;120(8):1243-1245. doi: 10.1161/CIRCRESAHA.116.310119. Review. No abstract available.

8.

Using exercise to measure and modify cardiac function.

Platt C, Houstis N, Rosenzweig A.

Cell Metab. 2015 Feb 3;21(2):227-236. doi: 10.1016/j.cmet.2015.01.014. Review.

9.

Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: the role of abnormal peripheral oxygen extraction.

Dhakal BP, Malhotra R, Murphy RM, Pappagianopoulos PP, Baggish AL, Weiner RB, Houstis NE, Eisman AS, Hough SS, Lewis GD.

Circ Heart Fail. 2015 Mar;8(2):286-94. doi: 10.1161/CIRCHEARTFAILURE.114.001825. Epub 2014 Oct 24.

10.

Causes of exercise intolerance in heart failure with preserved ejection fraction: searching for consensus.

Houstis NE, Lewis GD.

J Card Fail. 2014 Oct;20(10):762-778. doi: 10.1016/j.cardfail.2014.07.010. Epub 2014 Aug 7. Review.

PMID:
25108084
11.

The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance.

Yan QW, Yang Q, Mody N, Graham TE, Hsu CH, Xu Z, Houstis NE, Kahn BB, Rosen ED.

Diabetes. 2007 Oct;56(10):2533-40. Epub 2007 Jul 16.

12.

Reactive oxygen species have a causal role in multiple forms of insulin resistance.

Houstis N, Rosen ED, Lander ES.

Nature. 2006 Apr 13;440(7086):944-8.

PMID:
16612386
13.

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC.

Nat Genet. 2003 Jul;34(3):267-73.

PMID:
12808457

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