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Items: 1 to 50 of 231

1.

Differential microRNA-21 and microRNA-221 Upregulation in the Biventricular Failing Heart Reveals Distinct Stress Responses of Right Versus Left Ventricular Fibroblasts.

Powers JC, Sabri A, Al-Bataineh D, Chotalia D, Guo X, Tsipenyuk F, Berretta R, Kavitha P, Gopi H, Houser SR, Khan M, Tsai EJ, Recchia FA.

Circ Heart Fail. 2020 Jan;13(1):e006426. doi: 10.1161/CIRCHEARTFAILURE.119.006426. Epub 2020 Jan 9.

PMID:
31916447
2.

HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.

Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaay7205. doi: 10.1126/scitranslmed.aay7205.

PMID:
31915304
3.

Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis.

Garikipati VNS, Verma SK, Cheng Z, Liang D, Truongcao MM, Cimini M, Yue Y, Huang G, Wang C, Benedict C, Tang Y, Mallaredy V, Ibetti J, Grisanti L, Schumacher SM, Gao E, Rajan S, Wilusz JE, Goukassian D, Houser SR, Koch WJ, Kishore R.

Nat Commun. 2019 Sep 20;10(1):4317. doi: 10.1038/s41467-019-11777-7.

4.

Cortical bone-derived stem cell therapy reduces apoptosis after myocardial infarction.

Hobby ARH, Sharp TE 3rd, Berretta RM, Borghetti G, Feldsott E, Mohsin S, Houser SR.

Am J Physiol Heart Circ Physiol. 2019 Oct 1;317(4):H820-H829. doi: 10.1152/ajpheart.00144.2019. Epub 2019 Aug 23.

PMID:
31441690
5.

Cardiometabolic Heart Failure and HFpEF: Still Chasing Unicorns.

Sharp TE 3rd, Lefer DJ, Houser SR.

JACC Basic Transl Sci. 2019 Jun 24;4(3):422-424. doi: 10.1016/j.jacbts.2019.05.003. eCollection 2019 Jun. No abstract available.

6.

Acetylation of SERCA2a, Another Target for Heart Failure Treatment?

Chen X, Zhang X, Gross S, Houser SR, Soboloff J.

Circ Res. 2019 Apr 26;124(9):1285-1287. doi: 10.1161/CIRCRESAHA.119.315017. No abstract available.

PMID:
31021723
7.

Cardiomyocyte PKA Ablation Enhances Basal Contractility While Eliminates Cardiac β-Adrenergic Response Without Adverse Effects on the Heart.

Zhang Y, Wang WE, Zhang X, Li Y, Chen B, Liu C, Ai X, Zhang X, Tian Y, Zhang C, Tang M, Szeto C, Hua X, Xie M, Zeng C, Wu Y, Zhou L, Zhu W, Yu D, Houser SR, Chen X.

Circ Res. 2019 Jun 7;124(12):1760-1777. doi: 10.1161/CIRCRESAHA.118.313417. Epub 2019 Apr 15.

PMID:
30982412
8.

Transient Introduction of miR-294 in the Heart Promotes Cardiomyocyte Cell Cycle Reentry After Injury.

Borden A, Kurian J, Nickoloff E, Yang Y, Troupes CD, Ibetti J, Lucchese AM, Gao E, Mohsin S, Koch WJ, Houser SR, Kishore R, Khan M.

Circ Res. 2019 Jun 21;125(1):14-25. doi: 10.1161/CIRCRESAHA.118.314223. Epub 2019 Apr 9.

PMID:
30964391
9.

Prior β-blocker treatment decreases leukocyte responsiveness to injury.

Grisanti LA, de Lucia C, Thomas TP, Stark A, Strony JT, Myers VD, Beretta R, Yu D, Sardu C, Marfella R, Gao E, Houser SR, Koch WJ, Hamad EA, Tilley DG.

JCI Insight. 2019 Mar 28;5. pii: 99485. doi: 10.1172/jci.insight.99485.

10.

Cortical Bone Derived Stem Cells for Cardiac Wound Healing.

Mohsin S, Houser SR.

Korean Circ J. 2019 Apr;49(4):314-325. doi: 10.4070/kcj.2018.0437. Epub 2019 Jan 24. Review.

11.

GDF11 Decreases Pressure Overload-Induced Hypertrophy, but Can Cause Severe Cachexia and Premature Death.

Harper SC, Johnson J, Borghetti G, Zhao H, Wang T, Wallner M, Kubo H, Feldsott EA, Yang Y, Joo Y, Gou X, Sabri AK, Gupta P, Myzithras M, Khalil A, Franti M, Houser SR.

Circ Res. 2018 Nov 9;123(11):1220-1231. doi: 10.1161/CIRCRESAHA.118.312955.

12.

Diabetic Cardiomyopathy: Current and Future Therapies. Beyond Glycemic Control.

Borghetti G, von Lewinski D, Eaton DM, Sourij H, Houser SR, Wallner M.

Front Physiol. 2018 Oct 30;9:1514. doi: 10.3389/fphys.2018.01514. eCollection 2018. Review.

13.

Outcomes Associated With a Strategy of Adjuvant Metolazone or High-Dose Loop Diuretics in Acute Decompensated Heart Failure: A Propensity Analysis.

Brisco-Bacik MA, Ter Maaten JM, Houser SR, Vedage NA, Rao V, Ahmad T, Wilson FP, Testani JM.

J Am Heart Assoc. 2018 Sep 18;7(18):e009149. doi: 10.1161/JAHA.118.009149.

14.

Health behavior practice among understudied Chinese and Filipino Americans with cardiometabolic diseases.

Lee M, Hu D, Bunney G, Gadegbeku CA, Edmundowicz D, Houser SR, Wang H, Ma GX.

Prev Med Rep. 2018 Jun 2;11:240-246. doi: 10.1016/j.pmedr.2018.06.004. eCollection 2018 Sep.

15.

G protein-coupled receptor kinase 2 contributes to impaired fatty acid metabolism in the failing heart.

Pfleger J, Gross P, Johnson J, Carter RL, Gao E, Tilley DG, Houser SR, Koch WJ.

J Mol Cell Cardiol. 2018 Oct;123:108-117. doi: 10.1016/j.yjmcc.2018.08.025. Epub 2018 Aug 29.

PMID:
30171848
16.

Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction.

Sharp TE 3rd, Kubo H, Berretta RM, Starosta T, Wallner M, Schena GJ, Hobby AR, Yu D, Trappanese DM, George JC, Molkentin JD, Houser SR.

JACC Basic Transl Sci. 2017 Dec 25;2(6):669-683. doi: 10.1016/j.jacbts.2017.06.007. eCollection 2017 Dec.

17.

New Myocyte Formation in the Adult Heart: Endogenous Sources and Therapeutic Implications.

Vagnozzi RJ, Molkentin JD, Houser SR.

Circ Res. 2018 Jul 6;123(2):159-176. doi: 10.1161/CIRCRESAHA.118.311208. Review.

18.

Echocardiographic Strain Analysis for the Early Detection of Left Ventricular Systolic/Diastolic Dysfunction and Dyssynchrony in a Mouse Model of Physiological Aging.

de Lucia C, Wallner M, Eaton DM, Zhao H, Houser SR, Koch WJ.

J Gerontol A Biol Sci Med Sci. 2019 Mar 14;74(4):455-461. doi: 10.1093/gerona/gly139.

19.

Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association.

Musunuru K, Sheikh F, Gupta RM, Houser SR, Maher KO, Milan DJ, Terzic A, Wu JC; American Heart Association Council on Functional Genomics and Translational Biology; Council on Cardiovascular Disease in the Young; and Council on Cardiovascular and Stroke Nursing.

Circ Genom Precis Med. 2018 Jan;11(1):e000043. doi: 10.1161/HCG.0000000000000043. Epub 2018 Jan 12. Review.

20.

Does a Newly Characterized Cell From the Bone Marrow Repair the Heart After Acute Myocardial Infarction?

Houser SR.

Circ Res. 2018 Apr 13;122(8):1036-1038. doi: 10.1161/CIRCRESAHA.118.312954. No abstract available.

PMID:
29650624
21.

Long-Term Caloric Restriction Improves Cardiac Function, Remodeling, Adrenergic Responsiveness, and Sympathetic Innervation in a Model of Postischemic Heart Failure.

de Lucia C, Gambino G, Petraglia L, Elia A, Komici K, Femminella GD, D'Amico ML, Formisano R, Borghetti G, Liccardo D, Nolano M, Houser SR, Leosco D, Ferrara N, Koch WJ, Rengo G.

Circ Heart Fail. 2018 Mar;11(3):e004153. doi: 10.1161/CIRCHEARTFAILURE.117.004153.

22.

Increasing T-type calcium channel activity by β-adrenergic stimulation contributes to β-adrenergic regulation of heart rates.

Li Y, Zhang X, Zhang C, Zhang X, Li Y, Qi Z, Szeto C, Tang M, Peng Y, Molkentin JD, Houser SR, Xie M, Chen X.

J Physiol. 2018 Apr 1;596(7):1137-1151. doi: 10.1113/JP274756. Epub 2018 Jan 24.

23.

A Feline HFpEF Model with Pulmonary Hypertension and Compromised Pulmonary Function.

Wallner M, Eaton DM, Berretta RM, Borghetti G, Wu J, Baker ST, Feldsott EA, Sharp TE 3rd, Mohsin S, Oyama MA, von Lewinski D, Post H, Wolfson MR, Houser SR.

Sci Rep. 2017 Nov 29;7(1):16587. doi: 10.1038/s41598-017-15851-2.

24.

American Heart Association Principles on the Accessibility and Affordability of Drugs and Biologics: A Presidential Advisory From the American Heart Association.

Antman EM, Creager MA, Houser SR, Warner JJ, Konig M; American Heart Association.

Circulation. 2017 Dec 12;136(24):e441-e447. doi: 10.1161/CIR.0000000000000551. Epub 2017 Nov 9. Review.

PMID:
29122813
25.

Cortical Bone Stem Cell Therapy Preserves Cardiac Structure and Function After Myocardial Infarction.

Sharp TE 3rd, Schena GJ, Hobby AR, Starosta T, Berretta RM, Wallner M, Borghetti G, Gross P, Yu D, Johnson J, Feldsott E, Trappanese DM, Toib A, Rabinowitz JE, George JC, Kubo H, Mohsin S, Houser SR.

Circ Res. 2017 Nov 10;121(11):1263-1278. doi: 10.1161/CIRCRESAHA.117.311174. Epub 2017 Sep 14.

26.

microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases.

de Lucia C, Komici K, Borghetti G, Femminella GD, Bencivenga L, Cannavo A, Corbi G, Ferrara N, Houser SR, Koch WJ, Rengo G.

Front Med (Lausanne). 2017 Jun 12;4:74. doi: 10.3389/fmed.2017.00074. eCollection 2017. Review.

27.

Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.

Toib A, Zhang C, Borghetti G, Zhang X, Wallner M, Yang Y, Troupes CD, Kubo H, Sharp TE, Feldsott E, Berretta RM, Zalavadia N, Trappanese DM, Harper S, Gross P, Chen X, Mohsin S, Houser SR.

Am J Physiol Heart Circ Physiol. 2017 Sep 1;313(3):H620-H630. doi: 10.1152/ajpheart.00167.2017. Epub 2017 Jun 23.

28.

Dedifferentiation, Proliferation, and Redifferentiation of Adult Mammalian Cardiomyocytes After Ischemic Injury.

Wang WE, Li L, Xia X, Fu W, Liao Q, Lan C, Yang D, Chen H, Yue R, Zeng C, Zhou L, Zhou B, Duan DD, Chen X, Houser SR, Zeng C.

Circulation. 2017 Aug 29;136(9):834-848. doi: 10.1161/CIRCULATIONAHA.116.024307. Epub 2017 Jun 22.

29.

The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.

Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, Elrod JW.

Nature. 2017 May 4;545(7652):93-97. doi: 10.1038/nature22082. Epub 2017 Apr 26.

30.

Caveolae-localized L-type Ca2+ channels do not contribute to function or hypertrophic signalling in the mouse heart.

Correll RN, Makarewich CA, Zhang H, Zhang C, Sargent MA, York AJ, Berretta RM, Chen X, Houser SR, Molkentin JD.

Cardiovasc Res. 2017 Jun 1;113(7):749-759. doi: 10.1093/cvr/cvx046.

31.

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.

Cho GS, Lee DI, Tampakakis E, Murphy S, Andersen P, Uosaki H, Chelko S, Chakir K, Hong I, Seo K, Chen HV, Chen X, Basso C, Houser SR, Tomaselli GF, O'Rourke B, Judge DP, Kass DA, Kwon C.

Cell Rep. 2017 Jan 10;18(2):571-582. doi: 10.1016/j.celrep.2016.12.040.

32.

The American Heart Association's New Institute for Precision Cardiovascular Medicine.

Houser SR.

Circulation. 2016 Dec 13;134(24):1913-1914. Epub 2016 Nov 22. No abstract available.

PMID:
27881558
33.

American College of Cardiology and American Heart Association: Setting a New Standard for Hospital Accreditation-Together.

Chazal RA, Houser SR.

Circulation. 2016 Dec 13;134(24):2028-2029. Epub 2016 Nov 1. No abstract available.

PMID:
27803038
34.

Acute Catecholamine Exposure Causes Reversible Myocyte Injury Without Cardiac Regeneration.

Wallner M, Duran JM, Mohsin S, Troupes CD, Vanhoutte D, Borghetti G, Vagnozzi RJ, Gross P, Yu D, Trappanese DM, Kubo H, Toib A, Sharp TE 3rd, Harper SC, Volkert MA, Starosta T, Feldsott EA, Berretta RM, Wang T, Barbe MF, Molkentin JD, Houser SR.

Circ Res. 2016 Sep 16;119(7):865-79. doi: 10.1161/CIRCRESAHA.116.308687. Epub 2016 Jul 26.

35.

Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation.

Seki M, LaCanna R, Powers JC, Vrakas C, Liu F, Berretta R, Chacko G, Holten J, Jadiya P, Wang T, Arkles JS, Copper JM, Houser SR, Huang J, Patel VV, Recchia FA.

J Pharmacol Exp Ther. 2016 Sep;358(3):441-9. doi: 10.1124/jpet.116.234591. Epub 2016 Jun 27.

36.

MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.

Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, Jaña F, Huang J, Barrero C, Rabinowitz JE, Luongo TS, Schumacher SM, Rockman ME, Dietrich A, Merali S, Caplan J, Stathopulos P, Ahima RS, Cheung JY, Houser SR, Koch WJ, Patel V, Gohil VM, Elrod JW, Rajan S, Madesh M.

Cell Rep. 2016 May 24;15(8):1673-85. doi: 10.1016/j.celrep.2016.04.050. Epub 2016 May 12.

37.

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.

Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, Molkentin JD.

Cell. 2016 May 19;165(5):1147-1159. doi: 10.1016/j.cell.2016.04.002. Epub 2016 Apr 21.

38.

Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?

Harper SC, Brack A, MacDonnell S, Franti M, Olwin BB, Bailey BA, Rudnicki MA, Houser SR.

Circ Res. 2016 Apr 1;118(7):1143-50; discussion 1150. doi: 10.1161/CIRCRESAHA.116.307962.

39.

Opportunities for the Cardiovascular Community in the Precision Medicine Initiative.

Shah SH, Arnett D, Houser SR, Ginsburg GS, MacRae C, Mital S, Loscalzo J, Hall JL.

Circulation. 2016 Jan 12;133(2):226-31. doi: 10.1161/CIRCULATIONAHA.115.019475.

PMID:
27028435
40.

Nuquantus: Machine learning software for the characterization and quantification of cell nuclei in complex immunofluorescent tissue images.

Gross P, Honnorat N, Varol E, Wallner M, Trappanese DM, Sharp TE, Starosta T, Duran JM, Koller S, Davatzikos C, Houser SR.

Sci Rep. 2016 Mar 23;6:23431. doi: 10.1038/srep23431.

41.

A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle.

Nelson BR, Makarewich CA, Anderson DM, Winders BR, Troupes CD, Wu F, Reese AL, McAnally JR, Chen X, Kavalali ET, Cannon SC, Houser SR, Bassel-Duby R, Olson EN.

Science. 2016 Jan 15;351(6270):271-5. doi: 10.1126/science.aad4076.

42.

Caspase-1 mediates hyperlipidemia-weakened progenitor cell vessel repair.

Li YF, Huang X, Li X, Gong R, Yin Y, Nelson J, Gao E, Zhang H, Hoffman NE, Houser SR, Madesh M, Tilley DG, Choi ET, Jiang X, Huang CX, Wang H, Yang XF.

Front Biosci (Landmark Ed). 2016 Jan 1;21:178-91.

43.

Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015.

Antman EM, Benjamin EJ, Harrington RA, Houser SR, Peterson ED, Bauman MA, Brown N, Bufalino V, Califf RM, Creager MA, Daugherty A, Demets DL, Dennis BP, Ebadollahi S, Jessup M, Lauer MS, Lo B, MacRae CA, McConnell MV, McCray AT, Mello MM, Mueller E, Newburger JW, Okun S, Packer M, Philippakis A, Ping P, Prasoon P, Roger VL, Singer S, Temple R, Turner MB, Vigilante K, Warner J, Wayte P; American Heart Association Data Sharing Summit Attendees.

J Am Heart Assoc. 2015 Nov 5;4(11). pii: e002810. doi: 10.1161/JAHA.115.002810.

44.

Acute aerobic exercise increases exogenously infused bone marrow cell retention in the heart.

Chirico EN, Ding D, Muthukumaran G, Houser SR, Starosta T, Mu A, Margulies KB, Libonati JR.

Physiol Rep. 2015 Oct;3(10). pii: e12566. doi: 10.14814/phy2.12566.

45.

Unique Features of Cortical Bone Stem Cells Associated With Repair of the Injured Heart.

Mohsin S, Troupes CD, Starosta T, Sharp TE, Agra EJ, Smith S, Duran JM, Zalavadia N, Zhou Y, Kubo H, Berretta RM, Houser SR.

Circ Res. 2015 Dec 4;117(12):1024-33. doi: 10.1161/CIRCRESAHA.115.307362. Epub 2015 Oct 15.

PMID:
26472818
46.

Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes.

Glukhov AV, Balycheva M, Sanchez-Alonso JL, Ilkan Z, Alvarez-Laviada A, Bhogal N, Diakonov I, Schobesberger S, Sikkel MB, Bhargava A, Faggian G, Punjabi PP, Houser SR, Gorelik J.

Circulation. 2015 Dec 22;132(25):2372-84. doi: 10.1161/CIRCULATIONAHA.115.018131. Epub 2015 Oct 8.

47.

SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore.

Shanmughapriya S, Rajan S, Hoffman NE, Higgins AM, Tomar D, Nemani N, Hines KJ, Smith DJ, Eguchi A, Vallem S, Shaikh F, Cheung M, Leonard NJ, Stolakis RS, Wolfers MP, Ibetti J, Chuprun JK, Jog NR, Houser SR, Koch WJ, Elrod JW, Madesh M.

Mol Cell. 2015 Oct 1;60(1):47-62. doi: 10.1016/j.molcel.2015.08.009. Epub 2015 Sep 17.

48.

GDF11 does not rescue aging-related pathological hypertrophy.

Smith SC, Zhang X, Zhang X, Gross P, Starosta T, Mohsin S, Franti M, Gupta P, Hayes D, Myzithras M, Kahn J, Tanner J, Weldon SM, Khalil A, Guo X, Sabri A, Chen X, MacDonnell S, Houser SR.

Circ Res. 2015 Nov 6;117(11):926-32. doi: 10.1161/CIRCRESAHA.115.307527. Epub 2015 Sep 17.

49.

STIM1 elevation in the heart results in aberrant Ca²⁺ handling and cardiomyopathy.

Correll RN, Goonasekera SA, van Berlo JH, Burr AR, Accornero F, Zhang H, Makarewich CA, York AJ, Sargent MA, Chen X, Houser SR, Molkentin JD.

J Mol Cell Cardiol. 2015 Oct;87:38-47. doi: 10.1016/j.yjmcc.2015.07.032. Epub 2015 Aug 1.

50.

Negative Regulation of miR-375 by Interleukin-10 Enhances Bone Marrow-Derived Progenitor Cell-Mediated Myocardial Repair and Function After Myocardial Infarction.

Garikipati VN, Krishnamurthy P, Verma SK, Khan M, Abramova T, Mackie AR, Qin G, Benedict C, Nickoloff E, Johnson J, Gao E, Losordo DW, Houser SR, Koch WJ, Kishore R.

Stem Cells. 2015 Dec;33(12):3519-29. doi: 10.1002/stem.2121. Epub 2015 Aug 25.

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