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Items: 1 to 50 of 236

1.

Role of Oxide/Metal Bilayer Electrodes in Solution Processed Organic Field Effect Transistors.

Ablat A, Kyndiah A, Houin G, Alic TY, Hirsch L, Abbas M.

Sci Rep. 2019 Apr 30;9(1):6685. doi: 10.1038/s41598-019-43237-z.

2.

A whole-body physiologically based pharmacokinetic (WB-PBPK) model of ciprofloxacin: a step towards predicting bacterial killing at sites of infection.

Sadiq MW, Nielsen EI, Khachman D, Conil JM, Georges B, Houin G, Laffont CM, Karlsson MO, Friberg LE.

J Pharmacokinet Pharmacodyn. 2017 Apr;44(2):69-79. doi: 10.1007/s10928-016-9486-9. Epub 2016 Aug 30.

3.

Medical and pharmacological approach to adjust the salbutamol anti-doping policy in athletes.

Pillard F, Lavit M, Cances VL, Rami J, Houin G, Didier A, Rivière D.

Respir Res. 2015 Dec 24;16:155. doi: 10.1186/s12931-015-0315-2.

4.

[Tuberculosis: relevance of isoniazid dosage in prevention of liver side effects].

Negri L, Le Grusse J, Séraissol P, Lavit M, Houin G, Gandia P.

Therapie. 2014 Nov-Dec;69(6):509-16. doi: 10.2515/therapie/2014202. Epub 2014 Oct 16. French.

PMID:
25314930
5.

Determination of plasma unbound fraction of voriconazole in patients treated with a prophylactic or a curative treatment.

Florent A, Gandia P, Seraissol P, Chatelut E, Houin G.

Ther Drug Monit. 2014 Dec;36(6):752-8. doi: 10.1097/FTD.0000000000000095.

PMID:
24819971
6.

Ceftazidime dosage regimen in intensive care unit patients: from a population pharmacokinetic approach to clinical practice via Monte Carlo simulations.

Georges B, Conil JM, Ruiz S, Seguin T, Cougot P, Fourcade O, Houin G, Saivin S.

Br J Clin Pharmacol. 2012 Apr;73(4):588-96. doi: 10.1111/j.1365-2125.2011.04117.x.

7.

Optimizing ciprofloxacin dosing in intensive care unit patients through the use of population pharmacokinetic-pharmacodynamic analysis and Monte Carlo simulations.

Khachman D, Conil JM, Georges B, Saivin S, Houin G, Toutain PL, Laffont CM.

J Antimicrob Chemother. 2011 Aug;66(8):1798-809. doi: 10.1093/jac/dkr220. Epub 2011 Jun 8.

PMID:
21653603
8.

Influence of pre-analytical conditions on plasma ribavirin concentrations.

Gandia P, Trancart S, Nicot F, Barange K, Alric L, Izopet J, Séraissol P, Lavit M, Houin G.

Arzneimittelforschung. 2010;60(10):636-9. doi: 10.1055/s-0031-1296338.

PMID:
21125815
9.

The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine.

Bonnefille P, Sezgin-Bayindir Z, Belkhelfa H, Arellano C, Gandia P, Woodley J, Houin G.

Fundam Clin Pharmacol. 2011 Feb;25(1):104-14. doi: 10.1111/j.1472-8206.2010.00904.x. Epub 2010 Dec 1.

PMID:
21121944
10.

Modification of aflatoxin B1 and ochratoxin A toxicokinetics in rats administered a yeast cell wall preparation.

Firmin S, Gandia P, Morgavi DP, Houin G, Jouany JP, Bertin G, Boudra H.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Aug;27(8):1153-60. doi: 10.1080/19440041003801174.

PMID:
20512710
11.

Bioequivalence studies: a new EMA guideline.

Houin G.

Arzneimittelforschung. 2010;60(4):169-70. doi: 10.1055/s-0031-1296267. No abstract available.

PMID:
20486464
12.

Population pharmacokinetics of ceftazidime in intensive care unit patients: influence of glomerular filtration rate, mechanical ventilation, and reason for admission.

Georges B, Conil JM, Seguin T, Ruiz S, Minville V, Cougot P, Decun JF, Gonzalez H, Houin G, Fourcade O, Saivin S.

Antimicrob Agents Chemother. 2009 Oct;53(10):4483-9. doi: 10.1128/AAC.00430-09. Epub 2009 Jul 27.

13.

Ciprofloxacin use in critically ill patients: pharmacokinetic and pharmacodynamic approaches.

Conil JM, Georges B, de Lussy A, Khachman D, Seguin T, Ruiz S, Cougot P, Fourcade O, Houin G, Saivin S.

Int J Antimicrob Agents. 2008 Dec;32(6):505-10. doi: 10.1016/j.ijantimicag.2008.05.019. Epub 2008 Sep 2.

PMID:
18768301
14.

Cefepime in intensive care unit patients: validation of a population pharmacokinetic approach and influence of covariables.

Georges B, Conil JM, Seguin T, Dieye E, Cougot P, Decun JF, Lavit M, Samii K, Houin G, Saivin S.

Int J Clin Pharmacol Ther. 2008 Apr;46(4):157-64.

PMID:
18397688
15.

Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter.

Lafforgue G, Arellano C, Vachoux C, Woodley J, Philibert C, Dupouy V, Bousquet-Mélou A, Gandia P, Houin G.

Fundam Clin Pharmacol. 2008 Apr;22(2):189-201. doi: 10.1111/j.1472-8206.2008.00572.x.

PMID:
18353114
16.

A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs. Zn gluconate) after a single administration to twelve healthy female volunteers.

Gandia P, Bour D, Maurette JM, Donazzolo Y, Duchène P, Béjot M, Houin G.

Int J Vitam Nutr Res. 2007 Jul;77(4):243-8.

PMID:
18271278
17.

Pharmacokinetics of ceftazidime and cefepime in burn patients: the importance of age and creatinine clearance.

Conil JM, Georges B, Lavit M, Seguin T, Tack I, Samii K, Chabanon G, Houin G, Saivin S.

Int J Clin Pharmacol Ther. 2007 Oct;45(10):529-38.

PMID:
17966838
18.

Pharmacokinetics and pharmacodynamics of intramuscular dermatan sulfate revisited : a single- and repeated-dose study in healthy volunteers.

Saivin S, Cambus JP, Thalamas C, Lau G, Boneu B, Houin G, Gianese F.

Clin Drug Investig. 2003;23(8):533-43.

PMID:
17535066
19.
20.

Intermittent administration of ceftazidime to burns patients: influence of glomerular filtration.

Conil JM, Georges B, Fourcade O, Seguin T, Houin G, Saivin S.

Int J Clin Pharmacol Ther. 2007 Mar;45(3):133-42.

PMID:
17416108
21.

A population pharmacokinetic approach to ceftazidime use in burn patients: influence of glomerular filtration, gender and mechanical ventilation.

Conil JM, Georges B, Lavit M, Laguerre J, Samii K, Houin G, Saivin S.

Br J Clin Pharmacol. 2007 Jul;64(1):27-35. Epub 2007 Feb 23.

22.
23.

Assessment of renal function in clinical practice at the bedside of burn patients.

Conil JM, Georges B, Fourcade O, Seguin T, Lavit M, Samii K, Houin G, Tack I, Saivin S.

Br J Clin Pharmacol. 2007 May;63(5):583-94. Epub 2006 Dec 7.

24.

Influence of renal function on trough serum concentrations of piperacillin in intensive care unit patients.

Conil JM, Georges B, Mimoz O, Dieye E, Ruiz S, Cougot P, Samii K, Houin G, Saivin S.

Intensive Care Med. 2006 Dec;32(12):2063-6. Epub 2006 Oct 24.

PMID:
17061021
25.

Influence of simulated weightlessness on the intramuscular and oral pharmacokinetics of promethazine in 12 human volunteers.

Gandia P, Saivin S, Le-Traon AP, Guell A, Houin G.

J Clin Pharmacol. 2006 Sep;46(9):1008-16.

PMID:
16920895
26.

Increased amikacin dosage requirements in burn patients receiving a once-daily regimen.

Conil JM, Georges B, Breden A, Segonds C, Lavit M, Seguin T, Coley N, Samii K, Chabanon G, Houin G, Saivin S.

Int J Antimicrob Agents. 2006 Sep;28(3):226-30. Epub 2006 Aug 14.

PMID:
16908121
27.

Risk of emergence of Pseudomonas aeruginosa resistance to beta-lactam antibiotics in intensive care units.

Georges B, Conil JM, Dubouix A, Archambaud M, Bonnet E, Saivin S, Lauwers-Cancès V, Cristini C, Cougot P, Decun JF, Mathe O, Chabanon G, Marty N, Seguin T, Houin G.

Crit Care Med. 2006 Jun;34(6):1636-41.

PMID:
16557152
28.

Pharmacokinetics of tenatoprazole, a newly synthesized proton pump inhibitor, in healthy male Caucasian volunteers.

Domagala F, Ficheux H, Houin G, Barré J.

Arzneimittelforschung. 2006;56(1):33-9.

PMID:
16478003
29.

The influence of weightlessness on pharmacokinetics.

Gandia P, Saivin S, Houin G.

Fundam Clin Pharmacol. 2005 Dec;19(6):625-36. Review.

PMID:
16313274
30.

Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of bupropion in rat everted gut sacs.

Arellano C, Philibert C, Vachoux C, Woodley J, Houin G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Dec 27;829(1-2):50-5. Epub 2005 Oct 24.

PMID:
16246642
31.

Cefepime in critically ill patients: continuous infusion vs. an intermittent dosing regimen.

Georges B, Conil JM, Cougot P, Decun JF, Archambaud M, Seguin T, Chabanon G, Virenque C, Houin G, Saivin S.

Int J Clin Pharmacol Ther. 2005 Aug;43(8):360-9.

PMID:
16119511
32.

Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of dextromethorphan in rat everted gut sacs.

Arellano C, Philibert C, Dane à Yakan EN, Vachoux C, Lacombe O, Woodley J, Houin G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 May 5;819(1):105-13.

PMID:
15797528
33.

Localisation of drug permeability along the rat small intestine, using markers of the paracellular, transcellular and some transporter routes.

Lacombe O, Woodley J, Solleux C, Delbos JM, Boursier-Neyret C, Houin G.

Eur J Pharm Sci. 2004 Dec;23(4-5):385-91.

PMID:
15567292
34.
35.

In vitro intestinal degradation and absorption of chondroitin sulfate, a glycosaminoglycan drug.

Barthe L, Woodley J, Lavit M, Przybylski C, Philibert C, Houin G.

Arzneimittelforschung. 2004;54(5):286-92.

PMID:
15212191
36.

Liquid chromatographic-mass spectrometric method to assess cytochrome P450-mediated metabolism of testosterone by rat everted gut sacs.

Arellano C, Philibert C, Lacombe O, Woodley J, Houin G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Aug 5;807(2):263-70.

PMID:
15203039
37.

Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo.

Cornaire G, Woodley J, Hermann P, Cloarec A, Arellano C, Houin G.

Int J Pharm. 2004 Jun 18;278(1):119-31.

PMID:
15158955
38.

Plasma kinetics and efficacy of oral megazol treatment in Trypanosoma brucei brucei-infected sheep.

Boda C, Enanga B, Dumet H, Chauviere G, Labrousse F, Couquet C, Saivin S, Houin G, Perie J, Dumas M, Bouteille B.

Vet Parasitol. 2004 May 26;121(3-4):213-23.

PMID:
15135860
39.
40.

Influence of simulated weightlessness on the oral pharmacokinetics of acetaminophen as a gastric emptying probe in man: a plasma and a saliva study.

Gandia P, Bareille MP, Saivin S, Le-Traon AP, Lavit M, Guell A, Houin G.

J Clin Pharmacol. 2003 Nov;43(11):1235-43.

PMID:
14551178
41.

[Gastrointestinal absorption of drugs through the digestive barrier].

Houin G, Woodley J.

Ann Pharm Fr. 2002 Nov;60(6):365-71. Review. French.

PMID:
12514501
42.

[Importance of a cefpirome-vancomycin combination on bactericidal kinetics in severe MRSA infections in intensive care].

Georges B, Roche C, Archambaud M, Decun JF, Cougot P, Conil JM, Chaminade B, Andrieu P, Saivin S, Bonnet E, Chabanon G, Houin G, Samii K, Virenque C.

Pathol Biol (Paris). 2002 Apr;50(3):161-8. French.

PMID:
11980329
43.
44.

The pharmacodynamics of tinzaparin in healthy volunteers.

Cambus JP, Saivin S, Heilmann JJ, Caplain H, Boneu B, Houin G.

Br J Haematol. 2002 Mar;116(3):649-52.

PMID:
11849226
45.

Development and evaluation of an HPLC urinalysis screening test for occupational exposure to 3,4- and 3,5-dichloroanilines.

El ML, Arellano C, Philibert C, Evrard P, Poey J, Houin G.

Int J Clin Pharmacol Ther. 2002 Jan;40(1):41-6.

PMID:
11837382
46.

Pharmacokinetics of reboxetine in healthy, elderly volunteers.

Bergmann JF, Laneury JP, Duchene P, Fleishaker JC, Houin G, Ségrestaa JM.

Eur J Drug Metab Pharmacokinet. 2000 Jul-Dec;25(3-4):195-8.

PMID:
11420889
47.

[Pharmacokinetics of drugs].

Houin G.

Rev Infirm. 2000 Sep;(63):33-5. French. No abstract available.

PMID:
11288429
48.

In vivo study of percutaneous absorption of 4-chloroaniline using microdialysis in the rat.

el Marbouh L, Arellano C, Philibert C, Evrard P, Poëy J, Houin G.

Arzneimittelforschung. 2000 Nov;50(11):1033-6.

PMID:
11148860
49.

Pharmacodynamic study of low molecular weight dermatan sulphate (Desmin) after a single subcutaneous administration in patients with renal insufficiency.

Saivin S, Boneu B, Ducret F, Pourrat J, Palazzini E, Zamboni W, Duchêne P, Houin G.

Arzneimittelforschung. 2000 Sep;50(9):821-6.

PMID:
11050699
50.

Pharmacokinetics and bioequivalence of two trimebutine formulations in healthy volunteers using desmethyl-trimebutine levels.

Saivin S, Lavit M, Michel F, Labaune JP, Martin A, Cahiez G, Donazzolo C, Chomard JM, Houin G.

Arzneimittelforschung. 2000 Aug;50(8):717-21.

PMID:
10994155

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