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Items: 1 to 50 of 65

1.

Tumor-Specific Zr-89 Immuno-PET Imaging in a Human Bladder Cancer Model.

Escorcia FE, Steckler JM, Abdel-Atti D, Price EW, Carlin SD, Scholz WW, Lewis JS, Houghton JL.

Mol Imaging Biol. 2018 Mar 5. doi: 10.1007/s11307-018-1177-z. [Epub ahead of print]

PMID:
29508263
2.

Preloading with Unlabeled CA19.9 Targeted Human Monoclonal Antibody Leads to Improved PET Imaging with 89Zr-5B1.

Houghton JL, Abdel-Atti D, Scholz WW, Lewis JS.

Mol Pharm. 2017 Mar 6;14(3):908-915. doi: 10.1021/acs.molpharmaceut.6b01130. Epub 2017 Feb 21.

3.

Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry.

Houghton JL, Membreno R, Abdel-Atti D, Cunanan KM, Carlin S, Scholz WW, Zanzonico PB, Lewis JS, Zeglis BM.

Mol Cancer Ther. 2017 Jan;16(1):124-133. doi: 10.1158/1535-7163.MCT-16-0503. Epub 2016 Nov 9.

4.

Thiosulfate oxidation by Thiomicrospira thermophila: metabolic flexibility in response to ambient geochemistry.

Houghton JL, Foustoukos DI, Flynn TM, Vetriani C, Bradley AS, Fike DA.

Environ Microbiol. 2016 Sep;18(9):3057-72. doi: 10.1111/1462-2920.13232. Epub 2016 Mar 21.

5.

Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer.

Houghton JL, Zeglis BM, Abdel-Atti D, Aggeler R, Sawada R, Agnew BJ, Scholz WW, Lewis JS.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15850-5. doi: 10.1073/pnas.1506542112. Epub 2015 Dec 14.

6.

Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides.

Thamban Chandrika N, Green KD, Houghton JL, Garneau-Tsodikova S.

ACS Med Chem Lett. 2015 Sep 30;6(11):1134-9. doi: 10.1021/acsmedchemlett.5b00255. eCollection 2015 Nov 12.

7.

(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.

Meyer JP, Houghton JL, Kozlowski P, Abdel-Atti D, Reiner T, Pillarsetty NV, Scholz WW, Zeglis BM, Lewis JS.

Bioconjug Chem. 2016 Feb 17;27(2):298-301. doi: 10.1021/acs.bioconjchem.5b00504. Epub 2015 Oct 28.

8.

Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses.

Houghton JL, Zeglis BM, Abdel-Atti D, Sawada R, Scholz WW, Lewis JS.

J Nucl Med. 2016 Mar;57(3):453-9. doi: 10.2967/jnumed.115.163824. Epub 2015 Oct 15.

9.

Challenges of Pancreatic Cancer.

Dimastromatteo J, Houghton JL, Lewis JS, Kelly KA.

Cancer J. 2015 May-Jun;21(3):188-93. doi: 10.1097/PPO.0000000000000109. Review.

10.

Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals.

Zeglis BM, Houghton JL, Evans MJ, Viola-Villegas N, Lewis JS.

Inorg Chem. 2014 Feb 17;53(4):1880-99. doi: 10.1021/ic401607z. Epub 2013 Dec 6.

11.

Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis.

Houghton JL, Biswas T, Chen W, Tsodikov OV, Garneau-Tsodikova S.

Chembiochem. 2013 Nov 4;14(16):2127-35. doi: 10.1002/cbic.201300359. Epub 2013 Sep 17.

12.

Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes.

Houghton JL, Green KD, Pricer RE, Mayhoub AS, Garneau-Tsodikova S.

J Antimicrob Chemother. 2013 Apr;68(4):800-5. doi: 10.1093/jac/dks497. Epub 2012 Dec 11.

13.

AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism.

Pinkosky SL, Filippov S, Srivastava RA, Hanselman JC, Bradshaw CD, Hurley TR, Cramer CT, Spahr MA, Brant AF, Houghton JL, Baker C, Naples M, Adeli K, Newton RS.

J Lipid Res. 2013 Jan;54(1):134-51. doi: 10.1194/jlr.M030528. Epub 2012 Nov 1.

14.

Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis.

Pricer RE, Houghton JL, Green KD, Mayhoub AS, Garneau-Tsodikova S.

Mol Biosyst. 2012 Oct 30;8(12):3305-13. doi: 10.1039/c2mb25341k.

15.

The structural basis for substrate versatility of chloramphenicol acetyltransferase CATI.

Biswas T, Houghton JL, Garneau-Tsodikova S, Tsodikov OV.

Protein Sci. 2012 Apr;21(4):520-30. doi: 10.1002/pro.2036. Epub 2012 Mar 6.

16.

Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4').

Porter VR, Green KD, Zolova OE, Houghton JL, Garneau-Tsodikova S.

Biochem Biophys Res Commun. 2010 Dec 3;403(1):85-90. doi: 10.1016/j.bbrc.2010.10.119. Epub 2010 Oct 30.

PMID:
21040710
17.

An experimental and theoretical approach to determining linkages between geochemical variability and microbial biodiversity in seafloor hydrothermal chimneys.

Houghton JL, Seyfried WE Jr.

Geobiology. 2010 Dec;8(5):457-70. doi: 10.1111/j.1472-4669.2010.00255.x. Epub 2010 Aug 18.

PMID:
20726900
18.

The future of aminoglycosides: the end or renaissance?

Houghton JL, Green KD, Chen W, Garneau-Tsodikova S.

Chembiochem. 2010 May 3;11(7):880-902. doi: 10.1002/cbic.200900779. Review.

19.

Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides.

Green KD, Chen W, Houghton JL, Fridman M, Garneau-Tsodikova S.

Chembiochem. 2010 Jan 4;11(1):119-26. doi: 10.1002/cbic.200900584.

20.

A brief office educational intervention improved referral rates for hypertension control in women.

Lewis V, Barnhart J, Houghton JL, Charney P.

Int J Cardiol. 2010 Mar 4;139(2):204-6. doi: 10.1016/j.ijcard.2008.08.024. Epub 2008 Sep 16.

PMID:
18799224
21.
22.

Continuous enrichment culturing of thermophiles under sulfate and nitrate-reducing conditions and at deep-sea hydrostatic pressures.

Houghton JL, Seyfried WE Jr, Banta AB, Reysenbach AL.

Extremophiles. 2007 Mar;11(2):371-82. Epub 2007 Jan 13.

PMID:
17221162
23.

Mortality in patients with microvascular disease.

Marks DS, Gudapati S, Prisant LM, Weir B, diDonato-Gonzalez C, Waller JL, Houghton JL.

J Clin Hypertens (Greenwich). 2004 Jun;6(6):304-9.

24.

African Americans with LVH demonstrate depressed sensitivity of the coronary microcirculation to stimulated relaxation.

Houghton JL, Strogatz DS, Torosoff MT, Smith VE, Fein SA, Kuhner PA, Philbin EF, Carr AA.

Hypertension. 2003 Sep;42(3):269-76. Epub 2003 Aug 11.

PMID:
12913059
25.

Refractory vasomotor angina in subclinical hyperthyroidism demonstrating focal and segmental coronary vasoconstriction.

DeTommasi A, Rogge S, Houghton JL.

J Invasive Cardiol. 2003 May;15(5):289-92.

PMID:
12730640
26.

Long-term cardiovascular consequences of diuretics vs calcium channel blockers vs angiotensin-converting enzyme inhibitors.

Houghton JL.

JAMA. 2003 Apr 23-30;289(16):2066; author reply 2069-70. No abstract available.

PMID:
12709454
27.
28.

The presence of African American race predicts improvement in coronary endothelial function after supplementary L-arginine.

Houghton JL, Philbin EF, Strogatz DS, Torosoff MT, Fein SA, Kuhner PA, Smith VE, Carr AA.

J Am Coll Cardiol. 2002 Apr 17;39(8):1314-22.

29.

Effect of cholesterol-lowering therapy on endothelial function.

Houghton JL.

Circulation. 2001 Jul 10;104(2):E6. No abstract available.

PMID:
11447096
30.

Cholesterol lowering with pravastatin improves resistance artery endothelial function: report of six subjects with normal coronary arteriograms.

Houghton JL, Pearson TA, Reed RG, Torosoff MT, Henches NL, Kuhner PA, Philbin EF.

Chest. 2000 Sep;118(3):756-60.

PMID:
10988199
32.

Spontaneous multivessel coronary artery dissection: repeated presentation in a healthy postmenopausal woman.

Judkins DA, Miller SJ, Capone RJ, Houghton JL.

Clin Cardiol. 1999 Oct;22(10):677-80.

33.
34.

Heterogeneous vasomotor responses of coronary conduit and resistance vessels in hypertension.

Houghton JL, Davison CA, Kuhner PA, Torossov MT, Strogatz DS, Carr AA.

J Am Coll Cardiol. 1998 Feb;31(2):374-82.

35.

Coronary vasomotor reactivity among normotensive African and white American subjects with chest pain.

Houghton JL, Carr AA, Strogatz DS, Michel AI, Phillip JL, Kuhner PA, Smith VE, Breisblatt WM.

Am J Med. 1997 Mar;102(3):245-51.

PMID:
9217592
36.

Effect of African-American race and hypertensive left ventricular hypertrophy on coronary vascular reactivity and endothelial function.

Houghton JL, Smith VE, Strogatz DS, Henches NL, Breisblatt WM, Carr AA.

Hypertension. 1997 Mar;29(3):706-14.

PMID:
9052885
37.

Coronary vasomotor function in a normotensive, nondiabetic referral population with normal coronary arteriograms.

Houghton JL, Smith VE, Breisblatt WM, Henches NL, Strogatz DS, Carr AA.

Am J Cardiol. 1996 Jun 1;77(14):1241-4.

PMID:
8651106
38.

Unstable angina.

Prisant LM, Houghton JL, Bottini PB, Carr AA.

Postgrad Med. 1994 Jul;96(1):88-95. doi: 10.1080/00325481.1994.11945876.

PMID:
29211551
39.

Unstable angina. Pharmaceutical versus invasive therapy.

Prisant LM, Houghton JL, Bottini PB, Carr AA.

Postgrad Med. 1994 Jul;96(1):88-95. Review.

PMID:
8022719
40.

Hypertensive heart disease.

Prisant LM, Houghton JL, Bottini PB, Carr AA.

Postgrad Med. 1994 Jun;95(6):59-76. doi: 10.1080/00325481.1994.11945843.

PMID:
29211613
41.

Hypertensive heart disease. How does blood pressure affect left ventricular mass?

Prisant LM, Houghton JL, Bottini PB, Carr AA.

Postgrad Med. 1994 May 1;95(6):59-62, 66-76. Review.

PMID:
8170874
42.

Racial differences in myocardial ischemia and coronary flow reserve in hypertension.

Houghton JL, Prisant LM, Carr AA, Flowers NC, Frank MJ.

J Am Coll Cardiol. 1994 Apr;23(5):1123-9.

43.

Correction of left ventricular ischemia in blacks with hypertensive heart disease.

Carr AA, Prisant LM, Houghton JL.

Am J Hypertens. 1993 Jul;6(7 Pt 2):271S-276S.

PMID:
8398011
44.
45.

Long-term severe pulmonary hypertension associated with right atrial myxoma.

Heck HA Jr, Gross CM, Houghton JL.

Chest. 1992 Jul;102(1):301-3.

PMID:
1623775
46.

Congestive heart failure with normal ejection fraction. A different mechanism requiring different therapy.

Rogers WB, Prisant LM, Houghton JL, Frank MJ.

Postgrad Med. 1992 Jun;91(8):207-14.

PMID:
1351287
47.

Pharmacotherapy of unstable angina.

Prisant LM, von Dohlen T, Rogers W, Houghton JL, Carr AA, Frank MJ.

J Clin Pharmacol. 1992 May;32(5):390-9. Review.

PMID:
1587955
48.

Postpartum myocardial infarction treated by balloon coronary angioplasty.

Saxena R, Nolan TE, von Dohlen T, Houghton JL.

Obstet Gynecol. 1992 May;79(5 ( Pt 2)):810-2.

PMID:
1565373
49.

Case report: acute presentation of pseudo myocardial infarction secondary to metastatic cancer.

Houghton JL, Sinden JR, Gross CM.

Am J Med Sci. 1992 Mar;303(3):170-3.

PMID:
1595779
50.

Pericarditis and myocarditis. Which is benign and which isn't?

Houghton JL.

Postgrad Med. 1992 Feb 1;91(2):273-8, 281-2. Review.

PMID:
1738746

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