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Items: 1 to 50 of 485

1.

Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study.

Wu W, Pierce LA, Zhang Y, Pipavath SNJ, Randolph TW, Lastwika KJ, Lampe PD, Houghton AM, Liu H, Xia L, Kinahan PE.

Eur Radiol. 2019 May 21. doi: 10.1007/s00330-019-06213-9. [Epub ahead of print]

PMID:
31115618
2.

Endogenous CD4+ T Cells Recognize Neoantigens in Lung Cancer Patients, Including Recurrent Oncogenic KRAS and ERBB2 (Her2) Driver Mutations.

Veatch JR, Jesernig BL, Kargl J, Fitzgibbon M, Lee SM, Baik C, Martins R, Houghton AM, Riddell SR.

Cancer Immunol Res. 2019 Jun;7(6):910-922. doi: 10.1158/2326-6066.CIR-18-0402. Epub 2019 May 1.

PMID:
31043415
3.

S-nitrosylation of cytoskeletal proteins.

Horenberg AL, Houghton AM, Pandey S, Seshadri V, Guilford WH.

Cytoskeleton (Hoboken). 2019 Apr 10. doi: 10.1002/cm.21520. [Epub ahead of print] Review.

PMID:
30969482
4.

Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states.

Daurio NA, Wang Y, Chen Y, Zhou H, Carballo-Jane E, Mane J, Rodriguez CG, Zafian P, Houghton A, Addona G, McLaren DG, Zhang R, Shyong BJ, Bateman K, Downes DP, Webb M, Kelley DE, Previs SF.

Am J Physiol Endocrinol Metab. 2019 Jun 1;316(6):E1105-E1117. doi: 10.1152/ajpendo.00459.2018. Epub 2019 Mar 26.

PMID:
30912961
5.

Associations between Green Building Design Strategies and Community Health Resilience to Extreme Heat Events: A Systematic Review of the Evidence.

Houghton A, Castillo-Salgado C.

Int J Environ Res Public Health. 2019 Feb 24;16(4). pii: E663. doi: 10.3390/ijerph16040663. Review.

6.

Common Mechanisms Linking Chronic Obstructive Pulmonary Disease and Lung Cancer.

Houghton AM.

Ann Am Thorac Soc. 2018 Dec;15(Supplement_4):S273-S277. doi: 10.1513/AnnalsATS.201808-537MG.

PMID:
30759018
7.

Alveolar Macrophage Apoptosis-Associated Bacterial Killing Helps Prevent Murine Pneumonia.

Preston JA, Bewley MA, Marriott HM, Houghton AM, Mohasin M, Jubrail J, Morris L, Stephenson YL, Cross S, Greaves DR, Craig RW, van Rooijen N, Bingle CD, Read RC, Mitchell TJ, Whyte MKB, Shapiro SD, Dockrell DH.

Am J Respir Crit Care Med. 2019 Jan 16. doi: 10.1164/rccm.201804-0646OC. [Epub ahead of print]

8.

Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules.

Lastwika KJ, Kargl J, Zhang Y, Zhu X, Lo E, Shelley D, Ladd JJ, Wu W, Kinahan P, Pipavath SNJ, Randolph TW, Shipley M, Lampe PD, Houghton AM.

Am J Respir Crit Care Med. 2019 May 15;199(10):1257-1266. doi: 10.1164/rccm.201804-0628OC.

PMID:
30422669
9.

fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys.

Zhao F, Holahan MA, Wang X, Uslaner JM, Houghton AK, Evelhoch JL, Winkelmann CT, Hines CDG.

PLoS One. 2018 Jun 5;13(6):e0198395. doi: 10.1371/journal.pone.0198395. eCollection 2018.

10.

Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects.

Vardigan JD, Houghton AK, Lange HS, Adarayan ED, Pall PS, Ballard JE, Henze DA, Uslaner JM.

J Pain Res. 2018 Apr 11;11:735-741. doi: 10.2147/JPR.S152879. eCollection 2018.

11.

Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.

Veatch JR, Lee SM, Fitzgibbon M, Chow IT, Jesernig B, Schmitt T, Kong YY, Kargl J, Houghton AM, Thompson JA, McIntosh M, Kwok WW, Riddell SR.

J Clin Invest. 2018 Apr 2;128(4):1563-1568. doi: 10.1172/JCI98689. Epub 2018 Mar 12.

12.

Health Co-Benefits of Green Building Design Strategies and Community Resilience to Urban Flooding: A Systematic Review of the Evidence.

Houghton A, Castillo-Salgado C.

Int J Environ Res Public Health. 2017 Dec 6;14(12). pii: E1519. doi: 10.3390/ijerph14121519. Review.

13.

Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.

Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB.

Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003.

14.

Sport Sampling Is Associated With Improved Landing Technique in Youth Athletes.

DiStefano LJ, Beltz EM, Root HJ, Martinez JC, Houghton A, Taranto N, Pearce K, McConnell E, Muscat C, Boyle S, Trojian TH.

Sports Health. 2018 Mar/Apr;10(2):160-168. doi: 10.1177/1941738117736056. Epub 2017 Nov 13.

15.

Calorimetric Study of the Activation of Hydrogen by Tris(pentafluorophenyl)borane and Trimesitylphosphine.

Houghton AY, Autrey T.

J Phys Chem A. 2017 Nov 22;121(46):8785-8790. doi: 10.1021/acs.jpca.7b08582. Epub 2017 Nov 9.

PMID:
29076731
16.

Chronic Obstructive Pulmonary Disease Alters Immune Cell Composition and Immune Checkpoint Inhibitor Efficacy in Non-Small Cell Lung Cancer.

Mark NM, Kargl J, Busch SE, Yang GHY, Metz HE, Zhang H, Hubbard JJ, Pipavath SNJ, Madtes DK, Houghton AM.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):325-336. doi: 10.1164/rccm.201704-0795OC.

17.

Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.

Budhu S, Schaer DA, Li Y, Toledo-Crow R, Panageas K, Yang X, Zhong H, Houghton AN, Silverstein SC, Merghoub T, Wolchok JD.

Sci Signal. 2017 Aug 29;10(494). pii: eaak9702. doi: 10.1126/scisignal.aak9702.

18.

Mutant IDH1 regulates the tumor-associated immune system in gliomas.

Amankulor NM, Kim Y, Arora S, Kargl J, Szulzewsky F, Hanke M, Margineantu DH, Rao A, Bolouri H, Delrow J, Hockenbery D, Houghton AM, Holland EC.

Genes Dev. 2017 Apr 15;31(8):774-786. doi: 10.1101/gad.294991.116. Epub 2017 May 2.

19.

Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model.

Pero JE, Rossi MA, Lehman HDGF, Kelly MJ 3rd, Mulhearn JJ, Wolkenberg SE, Cato MJ, Clements MK, Daley CJ, Filzen T, Finger EN, Gregan Y, Henze DA, Jovanovska A, Klein R, Kraus RL, Li Y, Liang A, Majercak JM, Panigel J, Urban MO, Wang J, Wang YH, Houghton AK, Layton ME.

Bioorg Med Chem Lett. 2017 Jun 15;27(12):2683-2688. doi: 10.1016/j.bmcl.2017.04.040. Epub 2017 Apr 22.

PMID:
28465103
20.

Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis.

Manicone AM, Gharib SA, Gong KQ, Eddy WE, Long ME, Frevert CW, Altemeier WA, Parks WC, Houghton AM.

Am J Pathol. 2017 Jun;187(6):1288-1300. doi: 10.1016/j.ajpath.2017.02.008. Epub 2017 Apr 8.

21.

Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice.

Roecker AJ, Egbertson M, Jones KLG, Gomez R, Kraus RL, Li Y, Koser AJ, Urban MO, Klein R, Clements M, Panigel J, Daley C, Wang J, Finger EN, Majercak J, Santarelli V, Gregan I, Cato M, Filzen T, Jovanovska A, Wang YH, Wang D, Joyce LA, Sherer EC, Peng X, Wang X, Sun H, Coleman PJ, Houghton AK, Layton ME.

Bioorg Med Chem Lett. 2017 May 15;27(10):2087-2093. doi: 10.1016/j.bmcl.2017.03.085. Epub 2017 Mar 30.

PMID:
28389149
22.

Strained in Planning Your Mouse Background? Using the HPA Stress Axis as a Biological Readout for Backcrossing Strategies.

Chan JC, Houghton AB, Bale TL.

Neuropsychopharmacology. 2017 Aug;42(9):1749-1751. doi: 10.1038/npp.2017.66. Epub 2017 Mar 31. No abstract available.

23.

An Approach to Developing Local Climate Change Environmental Public Health Indicators in a Rural District.

Houghton A, Austin J, Beerman A, Horton C.

J Environ Public Health. 2017;2017:3407325. doi: 10.1155/2017/3407325. Epub 2017 Mar 2. Review.

24.

fMRI study of the role of glutamate NMDA receptor in the olfactory adaptation in rats: Insights into cellular and molecular mechanisms of olfactory adaptation.

Zhao F, Wang X, Zariwala HA, Uslaner JM, Houghton AK, Evelhoch JL, Hostetler E, Winkelmann CT, Hines CDG.

Neuroimage. 2017 Apr 1;149:348-360. doi: 10.1016/j.neuroimage.2017.01.068. Epub 2017 Feb 3.

PMID:
28163142
25.

Neutrophils dominate the immune cell composition in non-small cell lung cancer.

Kargl J, Busch SE, Yang GH, Kim KH, Hanke ML, Metz HE, Hubbard JJ, Lee SM, Madtes DK, McIntosh MW, Houghton AM.

Nat Commun. 2017 Feb 1;8:14381. doi: 10.1038/ncomms14381.

26.

Very late rupture of a post-traumatic abdominal aortic pseudoaneurysm.

Abed H, Ball WR, Stone T, Houghton A.

BMJ Case Rep. 2017 Jan 27;2017. pii: bcr2016218356. doi: 10.1136/bcr-2016-218356.

27.

Lung Cancer Subtypes Generate Unique Immune Responses.

Busch SE, Hanke ML, Kargl J, Metz HE, MacPherson D, Houghton AM.

J Immunol. 2016 Dec 1;197(11):4493-4503. Epub 2016 Oct 31.

28.

Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.

Metz HE, Kargl J, Busch SE, Kim KH, Kurland BF, Abberbock SR, Randolph-Habecker J, Knoblaugh SE, Kolls JK, White MF, Houghton AM.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8795-800. doi: 10.1073/pnas.1601989113. Epub 2016 Jul 20.

29.

Distinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman Primates.

Asad AB, Seah S, Baumgartner R, Feng D, Jensen A, Manigbas E, Henry B, Houghton A, Evelhoch JL, Derbyshire SW, Chin CL.

PLoS One. 2016 Jun 16;11(6):e0156805. doi: 10.1371/journal.pone.0156805. eCollection 2016.

30.

Assessing climate change and health vulnerability at the local level: Travis County, Texas.

Prudent N, Houghton A, Luber G.

Disasters. 2016 Oct;40(4):740-52. doi: 10.1111/disa.12177. Epub 2016 Jan 8.

PMID:
26748543
31.

A case of hepatopulmonary syndrome.

Offer J, Green L, Houghton AR, Campbell J.

Echo Res Pract. 2015 Jun 1;2(2):K25-7. doi: 10.1530/ERP-14-0100. Epub 2015 Mar 9.

32.

Right ventricular marantic endocarditis.

Dewey N, Mughal LH, Houghton AR, Khoo J.

Echo Res Pract. 2015 Mar 1;2(1):I3-I4. doi: 10.1530/ERP-14-0066. Epub 2014 Nov 25. No abstract available.

33.

Vein graft aneurysm with mural thrombus on echocardiography.

Dewey N, Houghton AR, Khoo J.

Echo Res Pract. 2015 Mar 1;2(1):I1-I2. doi: 10.1530/ERP-14-0054. Epub 2014 Nov 25. No abstract available.

34.

fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation.

Zhao F, Wang X, Zariwala HA, Uslaner JM, Houghton AK, Evelhoch JL, Williams DS, Winkelmann CT.

Neuroimage. 2016 Feb 15;127:445-455. doi: 10.1016/j.neuroimage.2015.10.080. Epub 2015 Oct 29.

PMID:
26522425
35.

Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.

Hidvegi T, Stolz DB, Alcorn JF, Yousem SA, Wang J, Leme AS, Houghton AM, Hale P, Ewing M, Cai H, Garchar EA, Pastore N, Annunziata P, Kaminski N, Pilewski J, Shapiro SD, Pak SC, Silverman GA, Brunetti-Pierri N, Perlmutter DH.

J Biol Chem. 2015 Dec 11;290(50):29742-57. doi: 10.1074/jbc.M115.691253. Epub 2015 Oct 22.

36.

Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.

Gregory AD, Kliment CR, Metz HE, Kim KH, Kargl J, Agostini BA, Crum LT, Oczypok EA, Oury TA, Houghton AM.

J Leukoc Biol. 2015 Aug;98(2):143-52. doi: 10.1189/jlb.3HI1014-493R. Epub 2015 Mar 5.

37.

Matrix metalloproteinases in destructive lung disease.

Houghton AM.

Matrix Biol. 2015 May-Jul;44-46:167-74. doi: 10.1016/j.matbio.2015.02.002. Epub 2015 Feb 14. Review.

38.

Functional imaging of olfaction by CBV fMRI in monkeys: insight into the role of olfactory bulb in habituation.

Zhao F, Holahan MA, Houghton AK, Hargreaves R, Evelhoch JL, Winkelmann CT, Williams DS.

Neuroimage. 2015 Feb 1;106:364-72. doi: 10.1016/j.neuroimage.2014.12.001. Epub 2014 Dec 10.

PMID:
25498426
39.

An approach to developing local climate change environmental public health indicators, vulnerability assessments, and projections of future impacts.

Houghton A, English P.

J Environ Public Health. 2014;2014:132057. doi: 10.1155/2014/132057. Epub 2014 Sep 30. Review.

40.

Direct observation of a borane-silane complex involved in frustrated Lewis-pair-mediated hydrosilylations.

Houghton AY, Hurmalainen J, Mansikkamäki A, Piers WE, Tuononen HM.

Nat Chem. 2014 Nov;6(11):983-8. doi: 10.1038/nchem.2063. Epub 2014 Sep 28.

PMID:
25343603
41.

Vein graft aneurysms following popliteal aneurysm repair are more common than we think.

Sharples A, Kay M, Sykes T, Fox A, Houghton A.

Vascular. 2015 Oct;23(5):494-7. doi: 10.1177/1708538114557070. Epub 2014 Oct 20.

PMID:
25331071
42.

Macrophage elastase suppresses white adipose tissue expansion with cigarette smoking.

Tsuji T, Kelly NJ, Takahashi S, Leme AS, Houghton AM, Shapiro SD.

Am J Respir Cell Mol Biol. 2014 Dec;51(6):822-9. doi: 10.1165/rcmb.2014-0083OC.

43.

Multilevel bypass grafting: is it worth it?

Sharples A, Kay M, Sykes T, Fox A, Houghton A.

Ann Vasc Surg. 2014 Oct;28(7):1697-702. doi: 10.1016/j.avsg.2014.03.027. Epub 2014 Apr 3.

PMID:
24704851
44.

GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability.

Schaer DA, Budhu S, Liu C, Bryson C, Malandro N, Cohen A, Zhong H, Yang X, Houghton AN, Merghoub T, Wolchok JD.

Cancer Immunol Res. 2013 Nov;1(5):320-31. doi: 10.1158/2326-6066.CIR-13-0086.

45.

Enhanced responses to tumor immunization following total body irradiation are time-dependent.

Diab A, Jenq RR, Rizzuto GA, Cohen AD, Huggins DW, Merghoub T, Engelhorn ME, Guevara-Patiño JA, Suh D, Hubbard-Lucey VM, Kochman AA, Chen S, Zhong H, Wolchok JD, van den Brink MR, Houghton AN, Perales MA.

PLoS One. 2013 Dec 12;8(12):e82496. doi: 10.1371/journal.pone.0082496. eCollection 2013.

46.

Hydrogen activation with perfluorinated organoboranes: 1,2,3-tris(pentafluorophenyl)-4,5,6,7-tetrafluoro-1-boraindene.

Houghton AY, Karttunen VA, Piers WE, Tuononen HM.

Chem Commun (Camb). 2014 Feb 9;50(11):1295-8. doi: 10.1039/c3cc48796b.

PMID:
24345791
47.

Qualification of fMRI as a biomarker for pain in anesthetized rats by comparison with behavioral response in conscious rats.

Zhao F, Williams M, Bowlby M, Houghton A, Hargreaves R, Evelhoch J, Williams DS.

Neuroimage. 2014 Jan 1;84:724-32. doi: 10.1016/j.neuroimage.2013.09.036. Epub 2013 Sep 21.

PMID:
24064074
48.

Uncommon adverse effects of commonly abused illicit drugs.

Patterson DA, Morris GW Jr, Houghton A.

Am Fam Physician. 2013 Jul 1;88(1):10-6. No abstract available.

49.

Two Distinct Categories of Focal Deletions in Cancer Genomes.

Rajaram M, Zhang J, Wang T, Li J, Kuscu C, Qi H, Kato M, Grubor V, Weil RJ, Helland A, Borrenson-Dale AL, Cho KR, Levine DA, Houghton AN, Wolchok JD, Myeroff L, Markowitz SD, Lowe SW, Zhang M, Krasnitz A, Lucito R, Mu D, Powers RS.

PLoS One. 2013 Jun 21;8(6):e66264. doi: 10.1371/journal.pone.0066264. Print 2013.

50.

Mechanistic links between COPD and lung cancer.

Houghton AM.

Nat Rev Cancer. 2013 Apr;13(4):233-45. doi: 10.1038/nrc3477. Epub 2013 Mar 7. Review.

PMID:
23467302

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