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Items: 1 to 50 of 179


Long Noncoding RNA: Genomics and Relevance to Physiology.

Kong Y, Lu Z, Liu P, Liu Y, Wang F, Liang EY, Hou FF, Liang M.

Compr Physiol. 2019 Jun 12;9(3):933-946. doi: 10.1002/cphy.c180032.


Visit-to-visit variability in blood pressure and the development of chronic kidney disease in treated general hypertensive patients.

Li Y, Li D, Song Y, Gao L, Fan F, Wang B, Liang M, Wang G, Li J, Zhang Y, Xu X, Hou FF, Cheng X, Sun N, Sun Y, Zhao L, Wan Q, Li X, Li J, Han Q, Xu X, Huo Y, Qin X.

Nephrol Dial Transplant. 2019 May 18. pii: gfz093. doi: 10.1093/ndt/gfz093. [Epub ahead of print]


Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial.

Heerspink HJL, Parving HH, Andress DL, Bakris G, Correa-Rotter R, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray JJV, Melnick JZ, Miller MG, Pergola PE, Perkovic V, Tobe S, Yi T, Wigderson M, de Zeeuw D; SONAR Committees and Investigators.

Lancet. 2019 May 11;393(10184):1937-1947. doi: 10.1016/S0140-6736(19)30772-X. Epub 2019 Apr 14. Erratum in: Lancet. 2019 May 11;393(10184):1936.


Matrix metalloproteinase-7 protects against acute kidney injury by priming renal tubules for survival and regeneration.

Fu H, Zhou D, Zhu H, Liao J, Lin L, Hong X, Hou FF, Liu Y.

Kidney Int. 2019 May;95(5):1167-1180. doi: 10.1016/j.kint.2018.11.043. Epub 2019 Mar 8.


Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria.

Zhou L, Chen X, Lu M, Wu Q, Yuan Q, Hu C, Miao J, Zhang Y, Li H, Hou FF, Nie J, Liu Y.

Kidney Int. 2019 Apr;95(4):830-845. doi: 10.1016/j.kint.2018.10.032. Epub 2019 Feb 12.


Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndrome.

Zhao Y, Wang C, Hong X, Miao J, Liao Y, Hou FF, Zhou L, Liu Y.

Kidney Int. 2019 Apr;95(4):815-829. doi: 10.1016/j.kint.2018.11.021. Epub 2019 Feb 12.


Wnt/β-catenin regulates blood pressure and kidney injury in rats.

Xiao L, Xu B, Zhou L, Tan RJ, Zhou D, Fu H, Li A, Hou FF, Liu Y.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1313-1322. doi: 10.1016/j.bbadis.2019.01.027. Epub 2019 Jan 30.


Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials.

Heerspink HJL, Greene T, Tighiouart H, Gansevoort RT, Coresh J, Simon AL, Chan TM, Hou FF, Lewis JB, Locatelli F, Praga M, Schena FP, Levey AS, Inker LA; Chronic Kidney Disease Epidemiology Collaboration.

Lancet Diabetes Endocrinol. 2019 Feb;7(2):128-139. doi: 10.1016/S2213-8587(18)30314-0. Epub 2019 Jan 8.


Plasma retinol and the risk of first stroke in hypertensive adults: a nested case-control study.

Yu Y, Zhang H, Song Y, Lin T, Zhou Z, Guo H, Liu L, Wang B, Liu C, Li J, Zhang Y, Huo Y, Wang C, Wang X, Hou FF, Qin X, Xu X.

Am J Clin Nutr. 2019 Feb 1;109(2):449-456. doi: 10.1093/ajcn/nqy320.


N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation.

Li C, Xie N, Li Y, Liu C, Hou FF, Wang J.

Free Radic Biol Med. 2019 Jan;130:512-527. doi: 10.1016/j.freeradbiomed.2018.11.006. Epub 2018 Nov 15.


A renal-cerebral-peripheral sympathetic reflex mediates insulin resistance in chronic kidney disease.

Cao W, Shi M, Wu L, Yang Z, Yang X, Liu H, Xu X, Liu Y, Wilcox CS, Hou FF.

EBioMedicine. 2018 Nov;37:281-293. doi: 10.1016/j.ebiom.2018.10.054. Epub 2018 Nov 11.


Efficacy of a novel inhibitor of vascular adhesion protein-1 in reducing albuminuria in patients with diabetic kidney disease (ALBUM): a randomised, placebo-controlled, phase 2 trial.

de Zeeuw D, Renfurm RW, Bakris G, Rossing P, Perkovic V, Hou FF, Nangaku M, Sharma K, Heerspink HJL, Garcia-Hernandez A, Larsson TE.

Lancet Diabetes Endocrinol. 2018 Dec;6(12):925-933. doi: 10.1016/S2213-8587(18)30289-4. Epub 2018 Nov 6.


Tenascin-C protects against acute kidney injury by recruiting Wnt ligands.

Chen S, Fu H, Wu S, Zhu W, Liao J, Hong X, Miao J, Luo C, Wang Y, Hou FF, Zhou L, Liu Y.

Kidney Int. 2019 Jan;95(1):62-74. doi: 10.1016/j.kint.2018.08.029. Epub 2018 Nov 6.


Serum Trimethylamine N-Oxide Concentration Is Positively Associated With First Stroke in Hypertensive Patients.

Nie J, Xie L, Zhao BX, Li Y, Qiu B, Zhu F, Li GF, He M, Wang Y, Wang B, Liu S, Zhang H, Guo H, Cai Y, Huo Y, Hou FF, Xu X, Qin X.

Stroke. 2018 Sep;49(9):2021-2028. doi: 10.1161/STROKEAHA.118.021997. Erratum in: Stroke. 2019 Jun;50(6):e175.


Acute Kidney Injury among Hospitalized Children in China.

Xu X, Nie S, Zhang A, Mao J, Liu HP, Xia H, Xu H, Liu Z, Feng S, Zhou W, Liu X, Yang Y, Tao Y, Feng Y, Chen C, Wang M, Zha Y, Feng JH, Li Q, Ge S, Chen J, He Y, Teng S, Hao C, Liu BC, Tang Y, He W, He P, Hou FF.

Clin J Am Soc Nephrol. 2018 Dec 7;13(12):1791-1800. doi: 10.2215/CJN.00800118. Epub 2018 Oct 4.


Belamchinanes A-D from Belamcanda chinensis: Triterpenoids with an Unprecedented Carbon Skeleton and Their Activity against Age-Related Renal Fibrosis.

Song YY, Miao JH, Qin FY, Yan YM, Yang J, Qin DP, Hou FF, Zhou LL, Cheng YX.

Org Lett. 2018 Sep 7;20(17):5506-5509. doi: 10.1021/acs.orglett.8b02490. Epub 2018 Aug 28.


A New Criterion for Pediatric AKI Based on the Reference Change Value of Serum Creatinine.

Xu X, Nie S, Zhang A, Jianhua M, Liu HP, Xia H, Xu H, Liu Z, Feng S, Zhou W, Liu X, Yang Y, Tao Y, Feng Y, Chen C, Wang M, Zha Y, Feng JH, Li Q, Ge S, Chen J, He Y, Teng S, Hao C, Liu BC, Tang Y, Wang LJ, Qi JL, He W, He P, Liu Y, Hou FF.

J Am Soc Nephrol. 2018 Sep;29(9):2432-2442. doi: 10.1681/ASN.2018010090. Epub 2018 Jul 27.


The Spectrum of Biopsy-Proven Glomerular Diseases among Children in China: A National, Cross-Sectional Survey.

Nie S, He W, Huang T, Liu D, Wang G, Geng J, Chen N, Xu G, Zhang P, Luo Y, Nie J, Xu X, Hou FF.

Clin J Am Soc Nephrol. 2018 Jul 6;13(7):1047-1054. doi: 10.2215/CJN.11461017. Epub 2018 Jun 18.


Platelet Count Affects Efficacy of Folic Acid in Preventing First Stroke.

Kong X, Huang X, Zhao M, Xu B, Xu R, Song Y, Yu Y, Yang W, Zhang J, Liu L, Zhang Y, Tang G, Wang B, Hou FF, Li P, Cheng X, Zhao S, Wang X, Qin X, Li J, Huo Y.

J Am Coll Cardiol. 2018 May 15;71(19):2136-2146. doi: 10.1016/j.jacc.2018.02.072.


Baseline characteristics and enrichment results from the SONAR trial.

Heerspink HJL, Andress DL, Bakris G, Brennan JJ, Correa-Rotter R, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray J, Perkovic V, Tobe S, Wigderson M, Yi T, Parving HH, de Zeeuw D.

Diabetes Obes Metab. 2018 Aug;20(8):1829-1835. doi: 10.1111/dom.13315. Epub 2018 May 1.


Environmental pollution and kidney diseases.

Xu X, Nie S, Ding H, Hou FF.

Nat Rev Nephrol. 2018 May;14(5):313-324. doi: 10.1038/nrneph.2018.11. Epub 2018 Feb 26. Review.


Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells.

Luo C, Zhou S, Zhou Z, Liu Y, Yang L, Liu J, Zhang Y, Li H, Liu Y, Hou FF, Zhou L.

J Am Soc Nephrol. 2018 Apr;29(4):1238-1256. doi: 10.1681/ASN.2017050574. Epub 2018 Feb 12.


Rationale and protocol of the Study Of diabetic Nephropathy with AtRasentan (SONAR) trial: A clinical trial design novel to diabetic nephropathy.

Heerspink HJL, Andress DL, Bakris G, Brennan JJ, Correa-Rotter R, Dey J, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray J, Perkovic V, Tobe S, Wigderson M, Parving HH, de Zeeuw D.

Diabetes Obes Metab. 2018 Jun;20(6):1369-1376. doi: 10.1111/dom.13245. Epub 2018 Mar 9.


Reply to J Dierkes et al.

Qin X, Li Y, Hou FF.

Am J Clin Nutr. 2018 Jan 1;107(1):132-133. doi: 10.1093/ajcn/nqx018. No abstract available.


MTHFR Gene and Serum Folate Interaction on Serum Homocysteine Lowering: Prospect for Precision Folic Acid Treatment.

Huang X, Qin X, Yang W, Liu L, Jiang C, Zhang X, Jiang S, Bao H, Su H, Li P, He M, Song Y, Zhao M, Yin D, Wang Y, Zhang Y, Li J, Yang R, Wu Y, Hong K, Wu Q, Chen Y, Sun N, Li X, Tang G, Wang B, Cai Y, Hou FF, Huo Y, Wang H, Wang X, Cheng X.

Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):679-685. doi: 10.1161/ATVBAHA.117.310211. Epub 2018 Jan 25.


Effect of Smoking and Folate Levels on the Efficacy of Folic Acid Therapy in Prevention of Stroke in Hypertensive Men.

Zhou Z, Li J, Yu Y, Li Y, Zhang Y, Liu L, Song Y, Zhao M, Wang Y, Tang G, He M, Xu X, Cai Y, Dong Q, Yin D, Huang X, Cheng X, Wang B, Hou FF, Wang X, Qin X, Huo Y.

Stroke. 2018 Jan;49(1):114-120. doi: 10.1161/STROKEAHA.117.018273. Erratum in: Stroke. 2018 Mar;49(3):e141.


Longitudinal Estimated GFR Trajectories in Patients With and Without Type 2 Diabetes and Nephropathy.

Weldegiorgis M, de Zeeuw D, Li L, Parving HH, Hou FF, Remuzzi G, Greene T, Heerspink HJL.

Am J Kidney Dis. 2018 Jan;71(1):91-101. doi: 10.1053/j.ajkd.2017.08.010. Epub 2017 Nov 16.


Impact of achieved blood pressure on renal function decline and first stroke in hypertensive patients with chronic kidney disease.

Li Y, Liang M, Jiang C, Wang G, Li J, Zhang Y, Fan F, Sun N, Cui Y, He M, Tang G, Yin D, Cheng X, Wang B, Huo Y, Xu X, Hou FF, Xu X, Qin X.

Nephrol Dial Transplant. 2018 Mar 1;33(3):409-417. doi: 10.1093/ndt/gfx267.


Association between percent decline in serum total homocysteine and risk of first stroke.

Huang X, Li Y, Li P, Li J, Bao H, Zhang Y, Wang B, Sun N, Wang J, He M, Yin D, Tang G, Chen Y, Cui Y, Huang Y, Hou FF, Qin X, Huo Y, Cheng X.

Neurology. 2017 Nov 14;89(20):2101-2107. doi: 10.1212/WNL.0000000000004648. Epub 2017 Oct 13.


Contrast-Enhanced Ultrasound for Assessing Renal Perfusion Impairment and Predicting Acute Kidney Injury to Chronic Kidney Disease Progression.

Cao W, Cui S, Yang L, Wu C, Liu J, Yang F, Liu Y, Bin J, Hou FF.

Antioxid Redox Signal. 2017 Dec 10;27(17):1397-1411. doi: 10.1089/ars.2017.7006. Epub 2017 Aug 22.


Urinary Matrix Metalloproteinase-7 Predicts Severe AKI and Poor Outcomes after Cardiac Surgery.

Yang X, Chen C, Teng S, Fu X, Zha Y, Liu H, Wang L, Tian J, Zhang X, Liu Y, Nie J, Hou FF.

J Am Soc Nephrol. 2017 Nov;28(11):3373-3382. doi: 10.1681/ASN.2017020142. Epub 2017 Jul 11.


Effects of Folic Acid Therapy on the New-Onset Proteinuria in Chinese Hypertensive Patients: A Post Hoc Analysis of the Renal Substudy of CSPPT (China Stroke Primary Prevention Trial).

Li Y, Liang M, Wang G, Wang B, He M, Tang G, Yin D, Xu X, Huo Y, Cui Y, Hou FF, Qin X.

Hypertension. 2017 Aug;70(2):300-306. doi: 10.1161/HYPERTENSIONAHA.117.09404. Epub 2017 Jun 12.


Folic acid therapy reduces the risk of mortality associated with heavy proteinuria among hypertensive patients.

Li Y, Qin X, Luo L, Wang B, Huo Y, Hou FF, Xu X.

J Hypertens. 2017 Jun;35(6):1302-1309. doi: 10.1097/HJH.0000000000001292.


Meta-analysis of folic acid efficacy trials in stroke prevention: Insight into effect modifiers.

Zhao M, Wu G, Li Y, Wang X, Hou FF, Xu X, Qin X, Cai Y.

Neurology. 2017 May 9;88(19):1830-1838. doi: 10.1212/WNL.0000000000003909. Epub 2017 Apr 12.


Association of serum uric acid with increased risk of cancer among hypertensive Chinese.

Yang J, Wang Y, Zhao Q, Zhang X, Wang X, Qin X, Zhang R, Shen L, Jiang X, Jiang H, Lei Y, Wang B, Gu J, Hou FF, Huo Y, Gao W, Xu X.

Int J Cancer. 2017 Jul 1;141(1):112-120. doi: 10.1002/ijc.30731. Epub 2017 Apr 24.


Homocysteine and Stroke Risk: Modifying Effect of Methylenetetrahydrofolate Reductase C677T Polymorphism and Folic Acid Intervention.

Zhao M, Wang X, He M, Qin X, Tang G, Huo Y, Li J, Fu J, Huang X, Cheng X, Wang B, Hou FF, Sun N, Cai Y.

Stroke. 2017 May;48(5):1183-1190. doi: 10.1161/STROKEAHA.116.015324. Epub 2017 Mar 30.


China Stroke Primary Prevention Trial: Visit-to-Visit Systolic Blood Pressure Variability Is an Independent Predictor of Primary Stroke in Hypertensive Patients.

Men X, Sun W, Fan F, Zhao M, Huang X, Wang Y, Liu L, Liu R, Sun W, Peng Q, Qin X, Tang G, Li J, Zhang Y, Cai Y, Hou FF, Wang B, Xu X, Cheng X, Sun N, Huang Y, Huo Y.

J Am Heart Assoc. 2017 Mar 13;6(3). pii: e004350. doi: 10.1161/JAHA.116.004350.


Impact of Achieved Blood Pressure on First Stroke in Uncomplicated Grade 1 Hypertension.

Qin X, Li Y, Sun N, He M, Tang G, Yin D, Wang J, Liang M, Wang B, Huo Y, Xu X, Xu X, Hou FF.

J Am Heart Assoc. 2017 Mar 8;6(3). pii: e005247. doi: 10.1161/JAHA.116.005247.


(Pro)renin Receptor Is an Amplifier of Wnt/β-Catenin Signaling in Kidney Injury and Fibrosis.

Li Z, Zhou L, Wang Y, Miao J, Hong X, Hou FF, Liu Y.

J Am Soc Nephrol. 2017 Aug;28(8):2393-2408. doi: 10.1681/ASN.2016070811. Epub 2017 Mar 7.


Advanced oxidation protein products promote NADPH oxidase-dependent β-cell destruction and dysfunction through the Bcl-2/Bax apoptotic pathway.

Liang M, Li A, Lou A, Zhang X, Chen Y, Yang L, Li Y, Yang S, Hou FF.

Lab Invest. 2017 Jul;97(7):792-805. doi: 10.1038/labinvest.2017.24. Epub 2017 Mar 6.


Advances in the Management of Acute Cardiorenal Syndrome in China: Biomarkers for Predicting Development and Outcomes.

Hou FF, Yang X.

Kidney Dis (Basel). 2017 Jan;2(4):145-150. doi: 10.1159/000449026. Epub 2016 Sep 10. Review.


Homocysteine and all-cause mortality in hypertensive adults without pre-existing cardiovascular conditions: Effect modification by MTHFR C677T polymorphism.

Xu B, Kong X, Xu R, Song Y, Liu L, Zhou Z, Gu R, Shi X, Zhao M, Huang X, He M, Fu J, Cai Y, Li P, Cheng X, Wu C, Chen F, Zhang Y, Tang G, Qin X, Wang B, Xue H, Chen Y, Tian Y, Sun N, Cui Y, Hou FF, Li J, Huo Y.

Medicine (Baltimore). 2017 Feb;96(8):e5862. doi: 10.1097/MD.0000000000005862.


The Nephroprotective Effect of Folic Acid-Only a Matter of Homocysteine?-Reply.

Hou FF, Xu X.

JAMA Intern Med. 2017 Feb 1;177(2):286-287. doi: 10.1001/jamainternmed.2016.8593. No abstract available.


Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT).

Qin X, Li Y, He M, Tang G, Yin D, Liang M, Wang B, Nie J, Huo Y, Xu X, Hou FF.

Am J Clin Nutr. 2017 Apr;105(4):882-889. doi: 10.3945/ajcn.116.143131. Epub 2017 Feb 1.


Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention.

Xu RB, Kong X, Xu BP, Song Y, Ji M, Zhao M, Huang X, Li P, Cheng X, Chen F, Zhang Y, Tang G, Qin X, Wang B, Hou FF, Dong Q, Chen Y, Yang T, Sun N, Li X, Zhao L, Ge J, Ji L, Huo Y, Li J.

Am J Clin Nutr. 2017 Mar;105(3):564-570. doi: 10.3945/ajcn.116.145656. Epub 2017 Jan 25.


Chronic kidney disease promotes chronic inflammation in visceral white adipose tissue.

Xiang DM, Song XZ, Zhou ZM, Liu Y, Dai XY, Huang XL, Hou FF, Zhou QG.

Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F689-F701. doi: 10.1152/ajprenal.00584.2016. Epub 2017 Jan 18.


Reno-Cerebral Reflex Activates the Renin-Angiotensin System, Promoting Oxidative Stress and Renal Damage After Ischemia-Reperfusion Injury.

Cao W, Li A, Li J, Wu C, Cui S, Zhou Z, Liu Y, Wilcox CS, Hou FF.

Antioxid Redox Signal. 2017 Sep 1;27(7):415-432. doi: 10.1089/ars.2016.6827. Epub 2017 Jan 31.


C-X-C Chemokine Receptor Type 4 Plays a Crucial Role in Mediating Oxidative Stress-Induced Podocyte Injury.

Mo H, Wu Q, Miao J, Luo C, Hong X, Wang Y, Tang L, Hou FF, Liu Y, Zhou L.

Antioxid Redox Signal. 2017 Aug 20;27(6):345-362. doi: 10.1089/ars.2016.6758. Epub 2017 Mar 28.


Association of peripheral differential leukocyte counts with dyslipidemia risk in Chinese patients with hypertension: insight from the China Stroke Primary Prevention Trial.

Liu Y, Kong X, Wang W, Fan F, Zhang Y, Zhao M, Wang Y, Wang Y, Wang Y, Qin X, Tang G, Wang B, Xu X, Hou FF, Gao W, Sun N, Li J, Venners SA, Jiang S, Huo Y.

J Lipid Res. 2017 Jan;58(1):256-266. doi: 10.1194/jlr.P067686. Epub 2016 Nov 22.


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