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Items: 1 to 50 of 56

1.

Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs.

Wünsche P, Eckert ESP, Holland-Letz T, Paruzynski A, Hotz-Wagenblatt A, Fronza R, Rath T, Gil-Farina I, Schmidt M, von Kalle C, Klein C, Ball CR, Herbst F, Glimm H.

Cell Stem Cell. 2018 Jul 5;23(1):132-146.e9. doi: 10.1016/j.stem.2018.06.003.

PMID:
29979988
2.

Functional characterization of the bovine foamy virus miRNA expression cassette and its dumbbell-shaped pri-miRNA.

Cao W, Heit A, Hotz-Wagenblatt A, Löchelt M.

Virus Genes. 2018 Aug;54(4):550-560. doi: 10.1007/s11262-018-1574-z. Epub 2018 May 31.

PMID:
29855776
3.

Immunoprofiling of Chlamydia trachomatis using whole-proteome microarrays generated by on-chip in situ expression.

Hufnagel K, Lueong S, Willhauck-Fleckenstein M, Hotz-Wagenblatt A, Miao B, Bauer A, Michel A, Butt J, Pawlita M, Hoheisel JD, Waterboer T.

Sci Rep. 2018 May 14;8(1):7503. doi: 10.1038/s41598-018-25918-3.

4.

Quantitative mass spectrometry analysis reveals a panel of nine proteins as diagnostic markers for colon adenocarcinomas.

Atak A, Khurana S, Gollapalli K, Reddy PJ, Levy R, Ben-Salmon S, Hollander D, Donyo M, Heit A, Hotz-Wagenblatt A, Biran H, Sharan R, Rane S, Shelar A, Ast G, Srivastava S.

Oncotarget. 2018 Feb 5;9(17):13530-13544. doi: 10.18632/oncotarget.24418. eCollection 2018 Mar 2.

5.

Translational profiling of B cells infected with the Epstein-Barr virus reveals 5' leader ribosome recruitment through upstream open reading frames.

Bencun M, Klinke O, Hotz-Wagenblatt A, Klaus S, Tsai MH, Poirey R, Delecluse HJ.

Nucleic Acids Res. 2018 Apr 6;46(6):2802-2819. doi: 10.1093/nar/gky129.

6.

Expression and replication of virus-like circular DNA in human cells.

Eilebrecht S, Hotz-Wagenblatt A, Sarachaga V, Burk A, Falida K, Chakraborty D, Nikitina E, Tessmer C, Whitley C, Sauerland C, Gunst K, Grewe I, Bund T.

Sci Rep. 2018 Feb 12;8(1):2851. doi: 10.1038/s41598-018-21317-w.

7.

Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.

Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M.

Nat Immunol. 2017 Nov 16;18(12):1361. doi: 10.1038/ni1217-1361b.

PMID:
29144491
8.

Identification of a novel metastasis inducing lncRNA which suppresses the KAI1/CD82 metastasis suppressor gene and is upregulated in triple-negative breast cancer.

Aram R, Dotan I, Hotz-Wagenblatt A, Canaani D.

Oncotarget. 2017 Jun 28;8(40):67538-67552. doi: 10.18632/oncotarget.18733. eCollection 2017 Sep 15.

9.

SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability.

Song C, Hotz-Wagenblatt A, Voit R, Grummt I.

Genes Dev. 2017 Jul 1;31(13):1370-1381. doi: 10.1101/gad.300624.117. Epub 2017 Aug 8.

10.

Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.

Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M.

Nat Immunol. 2017 Oct;18(10):1160-1172. doi: 10.1038/ni.3799. Epub 2017 Aug 7. Erratum in: Nat Immunol. 2017 Nov 16;18(12 ):1361.

11.

Genome-Wide Analysis of the Circulating miRNome After Cerebral Ischemia Reveals a Reperfusion-Induced MicroRNA Cluster.

Uhlmann S, Mracsko E, Javidi E, Lamble S, Teixeira A, Hotz-Wagenblatt A, Glatting KH, Veltkamp R.

Stroke. 2017 Mar;48(3):762-769. doi: 10.1161/STROKEAHA.116.013942. Epub 2017 Feb 13.

12.

miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A.

Bott A, Erdem N, Lerrer S, Hotz-Wagenblatt A, Breunig C, Abnaof K, Wörner A, Wilhelm H, Münstermann E, Ben-Baruch A, Wiemann S.

Oncotarget. 2017 Jul 4;8(27):43897-43914. doi: 10.18632/oncotarget.14915.

13.

Ago-RIP-Seq identifies Polycomb repressive complex I member CBX7 as a major target of miR-375 in prostate cancer progression.

Pickl JM, Tichy D, Kuryshev VY, Tolstov Y, Falkenstein M, Schüler J, Reidenbach D, Hotz-Wagenblatt A, Kristiansen G, Roth W, Hadaschik B, Hohenfellner M, Duensing S, Heckmann D, Sültmann H.

Oncotarget. 2016 Sep 13;7(37):59589-59603. doi: 10.18632/oncotarget.10729.

14.

miR-339-3p Is a Tumor Suppressor in Melanoma.

Weber CE, Luo C, Hotz-Wagenblatt A, Gardyan A, Kordaß T, Holland-Letz T, Osen W, Eichmüller SB.

Cancer Res. 2016 Jun 15;76(12):3562-71. doi: 10.1158/0008-5472.CAN-15-2932. Epub 2016 Apr 15.

15.

Replication-Competent Foamy Virus Vaccine Vectors as Novel Epitope Scaffolds for Immunotherapy.

Lei J, Osen W, Gardyan A, Hotz-Wagenblatt A, Wei G, Gissmann L, Eichmüller S, Löchelt M.

PLoS One. 2015 Sep 23;10(9):e0138458. doi: 10.1371/journal.pone.0138458. eCollection 2015.

16.

p53-dependent non-coding RNA networks in chronic lymphocytic leukemia.

Blume CJ, Hotz-Wagenblatt A, Hüllein J, Sellner L, Jethwa A, Stolz T, Slabicki M, Lee K, Sharathchandra A, Benner A, Dietrich S, Oakes CC, Dreger P, te Raa D, Kater AP, Jauch A, Merkel O, Oren M, Hielscher T, Zenz T.

Leukemia. 2015 Oct;29(10):2015-23. doi: 10.1038/leu.2015.119. Epub 2015 May 14.

PMID:
25971364
17.

Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing.

Rappe U, Schlechter T, Aschoff M, Hotz-Wagenblatt A, Hofmann I.

J Biol Chem. 2014 May 2;289(18):12421-34. doi: 10.1074/jbc.M113.530717. Epub 2014 Mar 18.

18.

Identification of the feline foamy virus Bet domain essential for APOBEC3 counteraction.

Lukic DS, Hotz-Wagenblatt A, Lei J, Räthe AM, Mühle M, Denner J, Münk C, Löchelt M.

Retrovirology. 2013 Jul 24;10:76. doi: 10.1186/1742-4690-10-76.

19.

Spatial localization of genes determined by intranuclear DNA fragmentation with the fusion proteins lamin KRED and histone KRED und visible light.

Waldeck W, Mueller G, Glatting KH, Hotz-Wagenblatt A, Diessl N, Chotewutmonti S, Langowski J, Semmler W, Wiessler M, Braun K.

Int J Med Sci. 2013 Jul 7;10(9):1136-48. doi: 10.7150/ijms.6121. Print 2013.

20.

ATF2 knockdown reinforces oxidative stress-induced apoptosis in TE7 cancer cells.

Walluscheck D, Poehlmann A, Hartig R, Lendeckel U, Schönfeld P, Hotz-Wagenblatt A, Reissig K, Bajbouj K, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2013 Aug;17(8):976-88. doi: 10.1111/jcmm.12071. Epub 2013 Jun 25.

21.

CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity.

von Bauer R, Oikonomou D, Sulaj A, Mohammed S, Hotz-Wagenblatt A, Gröne HJ, Arnold B, Falk C, Luethje D, Erhardt A, Stern DM, Bierhaus A, Nawroth PP.

J Immunol. 2013 Jul 1;191(1):369-77. doi: 10.4049/jimmunol.1201864. Epub 2013 May 31.

22.

In-depth mass spectrometric mapping of the human vitreous proteome.

Aretz S, Krohne TU, Kammerer K, Warnken U, Hotz-Wagenblatt A, Bergmann M, Stanzel BV, Kempf T, Holz FG, Schnölzer M, Kopitz J.

Proteome Sci. 2013 May 20;11(1):22. doi: 10.1186/1477-5956-11-22.

23.

SplicingCompass: differential splicing detection using RNA-seq data.

Aschoff M, Hotz-Wagenblatt A, Glatting KH, Fischer M, Eils R, König R.

Bioinformatics. 2013 May 1;29(9):1141-8. doi: 10.1093/bioinformatics/btt101. Epub 2013 Feb 28.

PMID:
23449093
24.

Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system.

Fredebohm J, Boettcher M, Eisen C, Gaida MM, Heller A, Keleg S, Tost J, Greulich-Bode KM, Hotz-Wagenblatt A, Lathrop M, Giese NA, Hoheisel JD.

PLoS One. 2012;7(11):e48503. doi: 10.1371/journal.pone.0048503. Epub 2012 Nov 12.

25.

miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes.

Luo C, Tetteh PW, Merz PR, Dickes E, Abukiwan A, Hotz-Wagenblatt A, Holland-Cunz S, Sinnberg T, Schittek B, Schadendorf D, Diederichs S, Eichmüller SB.

J Invest Dermatol. 2013 Mar;133(3):768-775. doi: 10.1038/jid.2012.357. Epub 2012 Nov 15.

26.

Comparative proteome analysis of Milnesium tardigradum in early embryonic state versus adults in active and anhydrobiotic state.

Schokraie E, Warnken U, Hotz-Wagenblatt A, Grohme MA, Hengherr S, Förster F, Schill RO, Frohme M, Dandekar T, Schnölzer M.

PLoS One. 2012;7(9):e45682. doi: 10.1371/journal.pone.0045682. Epub 2012 Sep 27.

27.

High-throughput SNP-based authentication of human cell lines.

Castro F, Dirks WG, Fähnrich S, Hotz-Wagenblatt A, Pawlita M, Schmitt M.

Int J Cancer. 2013 Jan 15;132(2):308-14. doi: 10.1002/ijc.27675. Epub 2012 Jun 28.

28.

Genome-wide prediction of splice-modifying SNPs in human genes using a new analysis pipeline called AASsites.

Faber K, Glatting KH, Mueller PJ, Risch A, Hotz-Wagenblatt A.

BMC Bioinformatics. 2011;12 Suppl 4:S2. doi: 10.1186/1471-2105-12-S4-S2. Epub 2011 Jul 5.

29.

Characteristics of transposable element exonization within human and mouse.

Sela N, Mersch B, Hotz-Wagenblatt A, Ast G.

PLoS One. 2010 Jun 1;5(6):e10907. doi: 10.1371/journal.pone.0010907.

30.

Proteomic analysis of tardigrades: towards a better understanding of molecular mechanisms by anhydrobiotic organisms.

Schokraie E, Hotz-Wagenblatt A, Warnken U, Mali B, Frohme M, Förster F, Dandekar T, Hengherr S, Schill RO, Schnölzer M.

PLoS One. 2010 Mar 3;5(3):e9502. doi: 10.1371/journal.pone.0009502.

31.

The transcriptome of the colonial marine hydroid Hydractinia echinata.

Soza-Ried J, Hotz-Wagenblatt A, Glatting KH, del Val C, Fellenberg K, Bode HR, Frank U, Hoheisel JD, Frohme M.

FEBS J. 2010 Jan;277(1):197-209. doi: 10.1111/j.1742-4658.2009.07474.x. Epub 2009 Dec 3.

32.

QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis.

Appelt JU, Giordano FA, Ecker M, Roeder I, Grund N, Hotz-Wagenblatt A, Opelz G, Zeller WJ, Allgayer H, Fruehauf S, Laufs S.

Gene Ther. 2009 Jul;16(7):885-93. doi: 10.1038/gt.2009.37. Epub 2009 Apr 23.

PMID:
19387483
33.

Automatic detection of exonic splicing enhancers (ESEs) using SVMs.

Mersch B, Gepperth A, Suhai S, Hotz-Wagenblatt A.

BMC Bioinformatics. 2008 Sep 10;9:369. doi: 10.1186/1471-2105-9-369.

34.

Off-target effects of siRNA specific for GFP.

Tschuch C, Schulz A, Pscherer A, Werft W, Benner A, Hotz-Wagenblatt A, Barrionuevo LS, Lichter P, Mertens D.

BMC Mol Biol. 2008 Jun 24;9:60. doi: 10.1186/1471-2199-9-60.

35.

Functions, structure, and read-through alternative splicing of feline APOBEC3 genes.

Münk C, Beck T, Zielonka J, Hotz-Wagenblatt A, Chareza S, Battenberg M, Thielebein J, Cichutek K, Bravo IG, O'Brien SJ, Löchelt M, Yuhki N.

Genome Biol. 2008;9(3):R48. doi: 10.1186/gb-2008-9-3-r48. Epub 2008 Mar 3.

36.

New miRNAs cloned from neuroblastoma.

Afanasyeva EA, Hotz-Wagenblatt A, Glatting KH, Westermann F.

BMC Genomics. 2008 Jan 29;9:52. doi: 10.1186/1471-2164-9-52.

37.
38.

New bioinformatic strategies to rapidly characterize retroviral integration sites of gene therapy vectors.

Giordano FA, Hotz-Wagenblatt A, Lauterborn D, Appelt JU, Fellenberg K, Nagy KZ, Zeller WJ, Suhai S, Fruehauf S, Laufs S.

Methods Inf Med. 2007;46(5):542-7.

PMID:
17938776
39.
40.

ProtSweep, 2Dsweep and DomainSweep: protein analysis suite at DKFZ.

del Val C, Ernst P, Falkenhahn M, Fladerer C, Glatting KH, Suhai S, Hotz-Wagenblatt A.

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W444-50. Epub 2007 May 25.

41.

Microarray analysis of newly synthesized RNA in cells and animals.

Kenzelmann M, Maertens S, Hergenhahn M, Kueffer S, Hotz-Wagenblatt A, Li L, Wang S, Ittrich C, Lemberger T, Arribas R, Jonnakuty S, Hollstein MC, Schmid W, Gretz N, Gröne HJ, Schütz G.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6164-9. Epub 2007 Apr 3.

42.

Induced and repressed genes after irradiation sensitizing by pentoxyphylline.

Waldeck W, Strunz AM, Müller G, Hotz-Wagenblatt A, Wijenne J, Langowski J, Didinger B, Debus J, Braun K.

Int J Cancer. 2007 Mar 15;120(6):1198-207.

43.

CAFTAN: a tool for fast mapping, and quality assessment of cDNAs.

del Val C, Kuryshev VY, Glatting KH, Ernst P, Hotz-Wagenblatt A, Poustka A, Suhai S, Wiemann S.

BMC Bioinformatics. 2006 Oct 25;7:473.

44.

Lentiviral vector integration sites in human NOD/SCID repopulating cells.

Laufs S, Guenechea G, Gonzalez-Murillo A, Zsuzsanna Nagy K, Luz Lozano M, del Val C, Jonnakuty S, Hotz-Wagenblatt A, Jens Zeller W, Bueren JA, Fruehauf S.

J Gene Med. 2006 Oct;8(10):1197-207.

PMID:
16960916
45.

Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions.

Giordano FA, Fehse B, Hotz-Wagenblatt A, Jonnakuty S, del Val C, Appelt JU, Nagy KZ, Kuehlcke K, Naundorf S, Zander AR, Zeller WJ, Ho AD, Fruehauf S, Laufs S.

Bone Marrow Transplant. 2006 Aug;38(3):229-35. Epub 2006 Jun 19.

PMID:
16785865
46.

Interdependent regulation of insulin receptor kinase activity by ADP and hydrogen peroxide.

Schmitt TL, Hotz-Wagenblatt A, Klein H, Dröge W.

J Biol Chem. 2005 Feb 4;280(5):3795-801. Epub 2004 Nov 23.

47.
48.
49.

ESTAnnotator: A tool for high throughput EST annotation.

Hotz-Wagenblatt A, Hankeln T, Ernst P, Glatting KH, Schmidt ER, Suhai S.

Nucleic Acids Res. 2003 Jul 1;31(13):3716-9.

50.

Redox-mediated functional and structural changes in insulin receptor kinase.

Hotz-Wagenblatt A, Dröge W.

Methods Enzymol. 2002;348:288-96. No abstract available.

PMID:
11885282

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