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Items: 1 to 50 of 575

1.

In Cellullo and ex Vivo Availability of a Yellowish-Green-Light-Controllable NO Releaser.

Ieda N, Hotta Y, Kawaguchi M, Kimura K, Nakagawa H.

Chem Pharm Bull (Tokyo). 2019;67(6):576-579. doi: 10.1248/cpb.c19-00112.

2.

Multicenter open-label randomized phase II study of second-line panitumumab and irinotecan with or without fluoropyrimidines in patients with KRAS wild-type metastatic colorectal cancer (PACIFIC study).

Nagata N, Maeda H, Ishibashi K, Hirata K, Makiyama A, Iwamoto S, Takemoto H, Imasato M, Yoshida Y, Munemoto Y, Tanaka C, Morita Y, Hotta Y, Toyofuku A, Nagasaka T, Morita S, Sakamoto J, Mishima H.

Med Oncol. 2019 Apr 24;36(6):46. doi: 10.1007/s12032-019-1254-4.

PMID:
31020480
3.

A Japanese family with cone-rod dystrophy of delayed onset caused by a compound heterozygous combination of novel CDHR1 frameshift and known missense variants.

Haque MN, Kurata K, Hosono K, Ohtsubo M, Ohishi K, Sato M, Minoshima S, Hotta Y.

Hum Genome Var. 2019 Apr 12;6:18. doi: 10.1038/s41439-019-0048-8. eCollection 2019.

4.

Testosterone Deficiency and Endothelial Dysfunction: Nitric Oxide, Asymmetric Dimethylarginine, and Endothelial Progenitor Cells.

Hotta Y, Kataoka T, Kimura K.

Sex Med Rev. 2019 Apr 12. pii: S2050-0521(19)30013-7. doi: 10.1016/j.sxmr.2019.02.005. [Epub ahead of print] Review.

PMID:
30987932
5.

X-linked Retinitis Pigmentosa in Japan: Clinical and Genetic Findings in Male Patients and Female Carriers.

Kurata K, Hosono K, Hayashi T, Mizobuchi K, Katagiri S, Miyamichi D, Nishina S, Sato M, Azuma N, Nakano T, Hotta Y.

Int J Mol Sci. 2019 Mar 26;20(6). pii: E1518. doi: 10.3390/ijms20061518.

6.

Increase of arginine dimethylation correlates with the progression and prognosis of ALS.

Ikenaka K, Atsuta N, Maeda Y, Hotta Y, Nakamura R, Kawai K, Yokoi D, Hirakawa A, Taniguchi A, Morita M, Mizoguchi K, Mochizuki H, Kimura K, Katsuno M, Sobue G.

Neurology. 2019 Apr 16;92(16):e1868-e1877. doi: 10.1212/WNL.0000000000007311. Epub 2019 Mar 13.

PMID:
30867270
7.

Photoinduced Electron Transfer-Regulated Protein Labeling With a Coumarin-Based Multifunctional Photocrosslinker.

Hotta Y, Kaneko T, Hayashi R, Yamamoto A, Morimoto S, Chiba J, Tomohiro T.

Chem Asian J. 2019 Feb 1;14(3):398-402. doi: 10.1002/asia.201801673. Epub 2019 Jan 14.

PMID:
30589233
8.

Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice.

Takagi T, Homma T, Fujii J, Shirasawa N, Yoriki H, Hotta Y, Higashimura Y, Mizushima K, Hirai Y, Katada K, Uchiyama K, Naito Y, Itoh Y.

Free Radic Biol Med. 2018 Dec 19;134:153-164. doi: 10.1016/j.freeradbiomed.2018.12.024. [Epub ahead of print]

PMID:
30578917
9.

Canagliflozin improves obesity and insulin resistance in a diabetic patient with Cushings disease undergoing postoperative steroid therapy: A case report.

Nishihama K, Furuta N, Maki K, Okano Y, Hashimoto R, Hotta Y, Uemura M, Yasuma T, Suzuki T, D'Alessandro-Gabazza CN, Yano Y, Gabazza EC.

Biomed Rep. 2018 Dec;9(6):497-502. doi: 10.3892/br.2018.1153. Epub 2018 Oct 1.

10.

[A case of cholangiolocellular carcinoma found to be hepatic hemangioma at 16-month follow up].

Yamaguchi K, Nagao Y, Yamane S, Takemura K, Oaku T, Hotta Y, Yamada N, Sekoguchi S, Isozaki Y, Oyamada H.

Nihon Shokakibyo Gakkai Zasshi. 2018;115(12):1078-1086. doi: 10.11405/nisshoshi.115.1078. Japanese.

PMID:
30531114
11.

Investigation of tolerability and quality of life for carboplatin-based chemotherapy in an elderly urothelial carcinoma patient undergoing hemodialysis: a case report.

Kondo M, Naiki T, Hotta Y, Yamamoto Y, Sugiyama Y, Yasui T, Kimura K.

J Pharm Health Care Sci. 2018 Nov 29;4:29. doi: 10.1186/s40780-018-0124-0. eCollection 2018.

12.

Brain-Specific Ultrastructure of Capillary Endothelial Glycocalyx and Its Possible Contribution for Blood Brain Barrier.

Ando Y, Okada H, Takemura G, Suzuki K, Takada C, Tomita H, Zaikokuji R, Hotta Y, Miyazaki N, Yano H, Muraki I, Kuroda A, Fukuda H, Kawasaki Y, Okamoto H, Kawaguchi T, Watanabe T, Doi T, Yoshida T, Ushikoshi H, Yoshida S, Ogura S.

Sci Rep. 2018 Nov 30;8(1):17523. doi: 10.1038/s41598-018-35976-2.

13.

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface.

Toyoda Y, Morimoto K, Suno R, Horita S, Yamashita K, Hirata K, Sekiguchi Y, Yasuda S, Shiroishi M, Shimizu T, Urushibata Y, Kajiwara Y, Inazumi T, Hotta Y, Asada H, Nakane T, Shiimura Y, Nakagita T, Tsuge K, Yoshida S, Kuribara T, Hosoya T, Sugimoto Y, Nomura N, Sato M, Hirokawa T, Kinoshita M, Murata T, Takayama K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T.

Nat Chem Biol. 2019 Jan;15(1):18-26. doi: 10.1038/s41589-018-0131-3. Epub 2018 Dec 3.

PMID:
30510193
14.

Crystal structure of the endogenous agonist-bound prostanoid receptor EP3.

Morimoto K, Suno R, Hotta Y, Yamashita K, Hirata K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T.

Nat Chem Biol. 2019 Jan;15(1):8-10. doi: 10.1038/s41589-018-0171-8. Epub 2018 Dec 3.

PMID:
30510192
15.

Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal-regulated kinase and Rho signaling.

Toyokawa Y, Takagi T, Uchiyama K, Mizushima K, Inoue K, Ushiroda C, Kashiwagi S, Nakano T, Hotta Y, Tanaka M, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Ishikawa T, Handa O, Konishi H, Naito Y, Itoh Y.

J Gastroenterol Hepatol. 2018 Nov 5. doi: 10.1111/jgh.14532. [Epub ahead of print]

PMID:
30394577
16.

Transforming growth factor β1-induced collagen production in myofibroblasts is mediated by reactive oxygen species derived from NADPH oxidase 4.

Hotta Y, Uchiyama K, Takagi T, Kashiwagi S, Nakano T, Mukai R, Toyokawa Y, Yasuda T, Ueda T, Suyama Y, Murakami T, Tanaka M, Majima A, Doi T, Hirai Y, Mizushima K, Morita M, Higashimura Y, Inoue K, Fukui A, Okayama T, Katada K, Kamada K, Handa O, Ishikawa T, Naito Y, Itoh Y.

Biochem Biophys Res Commun. 2018 Nov 30;506(3):557-562. doi: 10.1016/j.bbrc.2018.10.116. Epub 2018 Oct 23.

PMID:
30361098
17.

Outward open conformation of a Major Facilitator Superfamily multidrug/H+ antiporter provides insights into switching mechanism.

Nagarathinam K, Nakada-Nakura Y, Parthier C, Terada T, Juge N, Jaenecke F, Liu K, Hotta Y, Miyaji T, Omote H, Iwata S, Nomura N, Stubbs MT, Tanabe M.

Nat Commun. 2018 Oct 1;9(1):4005. doi: 10.1038/s41467-018-06306-x.

18.

Genotype determination of the OPN1LW/OPN1MW genes: novel disease-causing mechanisms in Japanese patients with blue cone monochromacy.

Katagiri S, Iwasa M, Hayashi T, Hosono K, Yamashita T, Kuniyoshi K, Ueno S, Kondo M, Ueyama H, Ogita H, Shichida Y, Inagaki H, Kurahashi H, Kondo H, Ohji M, Hotta Y, Nakano T.

Sci Rep. 2018 Jul 31;8(1):11507. doi: 10.1038/s41598-018-29891-9.

19.

Clinical and genetic findings of a Japanese patient with RP1-related autosomal recessive retinitis pigmentosa.

Kurata K, Hosono K, Hotta Y.

Doc Ophthalmol. 2018 Aug;137(1):47-56. doi: 10.1007/s10633-018-9649-7. Epub 2018 Jul 19.

PMID:
30027431
20.

Changes in conjunctival-scleral thickness after strabismus surgery measured with anterior segment optical coherence tomography.

Suzuki H, Hikoya A, Komori M, Inagaki R, Haseoka T, Arai S, Takagi Y, Hotta Y, Sato M.

Jpn J Ophthalmol. 2018 Sep;62(5):554-559. doi: 10.1007/s10384-018-0609-2. Epub 2018 Jul 6.

PMID:
29980870
21.

Essential and Non-essential Elements in Scalp Hair of Diabetics: Correlations with Glycated Hemoglobin (HbA1c).

Hotta Y, Fujino R, Kimura O, Endo T.

Biol Pharm Bull. 2018;41(7):1034-1039. doi: 10.1248/bpb.b18-00029.

22.

[A case of a gas-forming liver abscess caused by Clostridium perfringens after transcatheter arterial chemoembolization].

Takemura K, Sekoguchi S, Yamane S, Yamaguchi K, Oaku T, Hotta Y, Yamada N, Isozaki Y, Nagao Y, Oyamada H, Maeda K, Itou T.

Nihon Shokakibyo Gakkai Zasshi. 2018;115(6):554-562. doi: 10.11405/nisshoshi.115.554. Japanese.

PMID:
29887591
23.

Molecular Diagnosis of 34 Japanese Families with Leber Congenital Amaurosis Using Targeted Next Generation Sequencing.

Hosono K, Nishina S, Yokoi T, Katagiri S, Saitsu H, Kurata K, Miyamichi D, Hikoya A, Mizobuchi K, Nakano T, Minoshima S, Fukami M, Kondo H, Sato M, Hayashi T, Azuma N, Hotta Y.

Sci Rep. 2018 May 29;8(1):8279. doi: 10.1038/s41598-018-26524-z.

24.

Early onset flecked retinal dystrophy associated with new compound heterozygous RPE65 variants.

Katagiri S, Hosono K, Hayashi T, Kurata K, Mizobuchi K, Matsuura T, Yoshitake K, Iwata T, Nakano T, Hotta Y.

Mol Vis. 2018 Apr 9;24:286-296. eCollection 2018.

25.

Clinical characteristics of a Japanese patient with Bardet-Biedl syndrome caused by BBS10 mutations.

Kurata K, Hosono K, Hikoya A, Kato A, Saitsu H, Minoshima S, Ogata T, Hotta Y.

Jpn J Ophthalmol. 2018 Jul;62(4):458-466. doi: 10.1007/s10384-018-0591-8. Epub 2018 Apr 17.

PMID:
29666954
26.

Hepatitis B infection reported with cancer chemotherapy: analyzing the US FDA Adverse Event Reporting System.

Sanagawa A, Hotta Y, Kataoka T, Maeda Y, Kondo M, Kawade Y, Ogawa Y, Nishikawa R, Tohkin M, Kimura K.

Cancer Med. 2018 Jun;7(6):2269-2279. doi: 10.1002/cam4.1429. Epub 2018 Apr 16.

27.

Curing Effects on Interfacial Adhesion between Recycled Carbon Fiber and Epoxy Resin Heated by Microwave Irradiation.

Tominaga Y, Shimamoto D, Hotta Y.

Materials (Basel). 2018 Mar 26;11(4). pii: E493. doi: 10.3390/ma11040493.

28.

Ultrastructural Alteration of Pulmonary Capillary Endothelial Glycocalyx During Endotoxemia.

Inagawa R, Okada H, Takemura G, Suzuki K, Takada C, Yano H, Ando Y, Usui T, Hotta Y, Miyazaki N, Tsujimoto A, Zaikokuji R, Matsumoto A, Kawaguchi T, Doi T, Yoshida T, Yoshida S, Kumada K, Ushikoshi H, Toyoda I, Ogura S.

Chest. 2018 Aug;154(2):317-325. doi: 10.1016/j.chest.2018.03.003. Epub 2018 Mar 17.

29.

[Acute Urinary Retention Caused by Acute Disseminated Encephalomyelitis : A Case Report].

Fukui S, Iemura Y, Matsumura Y, Kagebayashi Y, Hotta Y, Yoshida S, Samma S.

Hinyokika Kiyo. 2018 Jan;64(1):17-20. doi: 10.14989/ActaUrolJap_64_1_17. Japanese.

30.

Long-term clinical course of 2 Japanese patients with PRPF31-related retinitis pigmentosa.

Kurata K, Hosono K, Hotta Y.

Jpn J Ophthalmol. 2018 Mar;62(2):186-193. doi: 10.1007/s10384-017-0560-7. Epub 2018 Jan 5.

PMID:
29305715
31.

Testosterone Deficiency Causes Endothelial Dysfunction via Elevation of Asymmetric Dimethylarginine and Oxidative Stress in Castrated Rats.

Kataoka T, Hotta Y, Maeda Y, Kimura K.

J Sex Med. 2017 Dec;14(12):1540-1548. doi: 10.1016/j.jsxm.2017.11.001.

PMID:
29198509
32.

Generation of Conformation-Specific Antibody Fragments for Crystallization of the Multidrug Resistance Transporter MdfA.

Jaenecke F, Nakada-Nakura Y, Nagarathinam K, Ogasawara S, Liu K, Hotta Y, Iwata S, Nomura N, Tanabe M.

Methods Mol Biol. 2018;1700:97-109. doi: 10.1007/978-1-4939-7454-2_7.

PMID:
29177828
33.

High salt loading induces urinary storage dysfunction via upregulation of epithelial sodium channel alpha in the bladder epithelium in Dahl salt-sensitive rats.

Yamamoto S, Hotta Y, Maeda K, Kataoka T, Maeda Y, Hamakawa T, Shibata Y, Sasaki S, Ugawa S, Yasui T, Kimura K.

J Pharmacol Sci. 2017 Nov;135(3):121-125. doi: 10.1016/j.jphs.2017.10.001. Epub 2017 Oct 10.

34.

The persistent inhibitory properties of saxagliptin on renal dipeptidyl peptidase-4: Studies with HK-2 cells in vitro and normal rats in vivo.

Uchii M, Sakai M, Hotta Y, Saeki S, Kimoto N, Hamaguchi A, Kitayama T, Kunori S.

J Pharmacol Sci. 2017 Nov;135(3):126-130. doi: 10.1016/j.jphs.2017.10.003. Epub 2017 Oct 23.

35.

Three-dimensional ultrastructure of capillary endothelial glycocalyx under normal and experimental endotoxemic conditions.

Okada H, Takemura G, Suzuki K, Oda K, Takada C, Hotta Y, Miyazaki N, Tsujimoto A, Muraki I, Ando Y, Zaikokuji R, Matsumoto A, Kitagaki H, Tamaoki Y, Usui T, Doi T, Yoshida T, Yoshida S, Ushikoshi H, Toyoda I, Ogura S.

Crit Care. 2017 Oct 23;21(1):261. doi: 10.1186/s13054-017-1841-8.

36.

Rebamipide upregulates mucin secretion of intestinal goblet cells via Akt phosphorylation.

Yasuda-Onozawa Y, Handa O, Naito Y, Ushiroda C, Suyama Y, Toyokawa Y, Murakami T, Yasuda T, Ueda T, Majima A, Hotta Y, Doi T, Tanaka M, Horii Y, Higashimura Y, Mizushima K, Morita M, Uehara Y, Horie H, Fukui A, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y.

Mol Med Rep. 2017 Dec;16(6):8216-8222. doi: 10.3892/mmr.2017.7647. Epub 2017 Sep 28.

PMID:
28983630
37.

ATYPICAL FORM OF RETINOPATHY OF PREMATURITY WITH SEVERE FIBROVASCULAR PROLIFERATION IN THE OPTIC DISK REGION.

Yokoi T, Katagiri S, Hiraoka M, Nakayama Y, Hosono K, Hotta Y, Nishina S, Azuma N.

Retina. 2018 Aug;38(8):1605-1612. doi: 10.1097/IAE.0000000000001779.

PMID:
28800017
38.

Ultrastructural aspects of vacuolar degeneration of cardiomyocytes in human endomyocardial biopsies.

Takemura G, Kanamori H, Okada H, Tsujimoto A, Miyazaki N, Takada C, Hotta Y, Takatsu Y, Fujiwara T, Fujiwara H.

Cardiovasc Pathol. 2017 Sep - Oct;30:64-71. doi: 10.1016/j.carpath.2017.06.012. Epub 2017 Jul 4. Review.

PMID:
28779645
39.

The multidrug-resistance transporter MdfA from Escherichia coli: crystallization and X-ray diffraction analysis.

Nagarathinam K, Jaenecke F, Nakada-Nakura Y, Hotta Y, Liu K, Iwata S, Stubbs MT, Nomura N, Tanabe M.

Acta Crystallogr F Struct Biol Commun. 2017 Jul 1;73(Pt 7):423-430. doi: 10.1107/S2053230X17008500. Epub 2017 Jun 20.

PMID:
28695852
40.

Visual Outcomes in Japanese Patients with Retinitis Pigmentosa and Usher Syndrome Caused by USH2A Mutations.

Nagase Y, Kurata K, Hosono K, Suto K, Hikoya A, Nakanishi H, Mizuta K, Mineta H, Minoshima S, Hotta Y.

Semin Ophthalmol. 2018;33(4):560-565. doi: 10.1080/08820538.2017.1340487. Epub 2017 Jul 5.

PMID:
28678594
41.

Development and evaluation of adsorption sheet (HD safe sheet-U) using active carbon for the purpose of the preventing the contamination diffusion of urinary excreted anticancer drug.

Sato J, Ohkubo H, Sasaki Y, Yokoi M, Hotta Y, Kudo K.

J Pharm Health Care Sci. 2017 Jun 2;3:16. doi: 10.1186/s40780-017-0085-8. eCollection 2017.

42.

Secreted protein acidic and rich in cysteine functions in colitis via IL17A regulation in mucosal CD4+ T cells.

Tanaka M, Takagi T, Naito Y, Uchiyama K, Hotta Y, Toyokawa Y, Ushiroda C, Hirai Y, Aoi W, Higashimura Y, Mizushima K, Okayama T, Katada K, Kamada K, Ishikawa T, Handa O, Itoh Y.

J Gastroenterol Hepatol. 2018 Mar;33(3):671-680. doi: 10.1111/jgh.13842.

PMID:
28582593
43.

Current situations and discussions in Japan in relation to the new occupational equivalent dose limit for the lens of the eye.

Yokoyama S, Hamada N, Hayashida T, Tsujimura N, Tatsuzaki H, Kurosawa T, Nabatame K, Ohguchi H, Ohno K, Yamauchi-Kawaura C, Iimoto T, Ichiji T, Hotta Y, Iwai S, Akahane K.

J Radiol Prot. 2017 Sep 25;37(3):659-683. doi: 10.1088/1361-6498/aa73e8. Epub 2017 May 18.

PMID:
28516892
44.

Long-Term Clinical Course in a Patient with Complete Congenital Stationary Night Blindness.

Kurata K, Hosono K, Hotta Y.

Case Rep Ophthalmol. 2017 Apr 10;8(1):237-244. doi: 10.1159/000462961. eCollection 2017 Jan-Apr.

45.

Higher Numbers of Hyperreflective Foci Seen in the Vitreous on Spectral-Domain Optical Coherence Tomographic Images in Eyes with More Severe Diabetic Retinopathy.

Mizukami T, Hotta Y, Katai N.

Ophthalmologica. 2017;238(1-2):74-80. doi: 10.1159/000473886. Epub 2017 May 10.

PMID:
28486219
46.

The impact of a solitary kidney on tolerability to gemcitabine plus cisplatin chemotherapy in urothelial carcinoma patients: a retrospective study.

Kondo M, Hotta Y, Ando R, Yasui T, Kimura K.

Cancer Chemother Pharmacol. 2017 May;79(5):995-1001. doi: 10.1007/s00280-017-3277-x. Epub 2017 Apr 8.

PMID:
28391352
47.

Assessment of Endoscopic Mucosal Healing of Ulcerative Colitis Using Linked Colour Imaging, a Novel Endoscopic Enhancement System.

Uchiyama K, Takagi T, Kashiwagi S, Toyokawa Y, Tanaka M, Hotta Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Ishikawa T, Handa O, Konishi H, Kishimoto M, Yagi N, Naito Y, Itoh Y.

J Crohns Colitis. 2017 Aug 1;11(8):963-969. doi: 10.1093/ecco-jcc/jjx026.

PMID:
28333209
48.

Curative effect of HF10 on liver and peritoneal metastasis mediated by host antitumor immunity.

Hotta Y, Kasuya H, Bustos I, Naoe Y, Ichinose T, Tanaka M, Kodera Y.

Oncolytic Virother. 2017 Mar 13;6:31-38. doi: 10.2147/OV.S127179. eCollection 2017.

49.

A yellowish-green-light-controllable nitric oxide donor based on N-nitrosoaminophenol applicable for photocontrolled vasodilation.

Okuno H, Ieda N, Hotta Y, Kawaguchi M, Kimura K, Nakagawa H.

Org Biomol Chem. 2017 Mar 28;15(13):2791-2796. doi: 10.1039/c7ob00245a.

PMID:
28272634
50.

Correlations between mercury concentration, and stable isotope ratios of carbon and nitrogen of amino acids in scalp hair from whale meat eaters and heavy fish eaters.

Endo T, Ogasawara H, Hayasaka M, Hotta Y, Kimura O, Petzke KJ.

Rapid Commun Mass Spectrom. 2017 May 15;31(9):745-752. doi: 10.1002/rcm.7841.

PMID:
28225553

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