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Items: 1 to 50 of 209

1.

Stress and the Home Environment in Caregivers of Children with Sickle Cell.

Varughese TE, Hoyt CR, L'Hotta AJ, Ikemenogo PA, Howdeshell SG, Housten AJ, Abel RA, King AA.

J Pediatr Psychol. 2020 Mar 31. pii: jsaa016. doi: 10.1093/jpepsy/jsaa016. [Epub ahead of print]

PMID:
32232470
2.

Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping.

Gee P, Lung MSY, Okuzaki Y, Sasakawa N, Iguchi T, Makita Y, Hozumi H, Miura Y, Yang LF, Iwasaki M, Wang XH, Waller MA, Shirai N, Abe YO, Fujita Y, Watanabe K, Kagita A, Iwabuchi KA, Yasuda M, Xu H, Noda T, Komano J, Sakurai H, Inukai N, Hotta A.

Nat Commun. 2020 Mar 13;11(1):1334. doi: 10.1038/s41467-020-14957-y.

3.

Temporal Muscle as an Indicator of Sarcopenia is Independently Associated with Hunt and Kosnik Grade on Admission and the Modified Rankin Scale Score at 6 Months of Patients with Subarachnoid Hemorrhage Treated by Endovascular Coiling.

Katsuki M, Suzuki Y, Kunitoki K, Sato Y, Sasaki K, Mashiyama S, Matsuoka R, Allen E, Saimaru H, Sugawara R, Hotta A, Tominaga T.

World Neurosurg. 2020 Feb 14. pii: S1878-8750(20)30298-9. doi: 10.1016/j.wneu.2020.02.033. [Epub ahead of print]

PMID:
32061954
4.

Lobe-specific outcomes of surgery for lung cancer patients with idiopathic interstitial pneumonias.

Fukui M, Takamochi K, Suzuki K, Hotta A, Ando K, Matsunaga T, Oh S, Suzuki K.

Gen Thorac Cardiovasc Surg. 2020 Feb 10. doi: 10.1007/s11748-019-01277-2. [Epub ahead of print]

PMID:
32040817
5.

Tissue-Engineered Vascular Grafts with Advanced Mechanical Strength from Human iPSCs.

Luo J, Qin L, Zhao L, Gui L, Ellis MW, Huang Y, Kural MH, Clark JA, Ono S, Wang J, Yuan Y, Zhang SM, Cong X, Li G, Riaz M, Lopez C, Hotta A, Campbell S, Tellides G, Dardik A, Niklason LE, Qyang Y.

Cell Stem Cell. 2020 Feb 6;26(2):251-261.e8. doi: 10.1016/j.stem.2019.12.012. Epub 2020 Jan 16.

PMID:
31956039
6.

iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity.

Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, Akasaka M, Nakamura S, Higashi N, Xu H, Matsumoto T, Fujio K, Manz MG, Hotta A, Takizawa H, Eto K, Sugimoto N.

Stem Cell Reports. 2020 Jan 14;14(1):49-59. doi: 10.1016/j.stemcr.2019.11.011. Epub 2019 Dec 26.

7.

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells.

Morisaka H, Yoshimi K, Okuzaki Y, Gee P, Kunihiro Y, Sonpho E, Xu H, Sasakawa N, Naito Y, Nakada S, Yamamoto T, Sano S, Hotta A, Takeda J, Mashimo T.

Nat Commun. 2019 Dec 6;10(1):5302. doi: 10.1038/s41467-019-13226-x.

8.

Development of a comprehensive pediatric oncology rehabilitation program.

L'Hotta AJ, Beam IA, Thomas KM.

Pediatr Blood Cancer. 2020 Feb;67(2):e28083. doi: 10.1002/pbc.28083. Epub 2019 Nov 17.

PMID:
31736277
9.

Effective methods for the inactivation of Francisella tularensis.

Azaki M, Uda A, Tian D, Nakazato K, Hotta A, Kawai Y, Ishijima K, Kuroda Y, Maeda K, Morikawa S.

PLoS One. 2019 Nov 14;14(11):e0225177. doi: 10.1371/journal.pone.0225177. eCollection 2019. Erratum in: PLoS One. 2019 Dec 2;14(12):e0226125.

10.

Unveiling Two Consecutive Hydroxylations: Mechanisms of Aromatic Hydroxylations Catalyzed by Flavin-Dependent Monooxygenases for the Biosynthesis of Actinorhodin and Related Antibiotics.

Hashimoto M, Taguchi T, Ishikawa K, Mori R, Hotta A, Watari S, Katakawa K, Kumamoto T, Okamoto S, Ichinose K.

Chembiochem. 2020 Mar 2;21(5):623-627. doi: 10.1002/cbic.201900490. Epub 2019 Nov 27.

PMID:
31532569
11.

In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids.

Korogi Y, Gotoh S, Ikeo S, Yamamoto Y, Sone N, Tamai K, Konishi S, Nagasaki T, Matsumoto H, Ito I, Chen-Yoshikawa TF, Date H, Hagiwara M, Asaka I, Hotta A, Mishima M, Hirai T.

Stem Cell Reports. 2019 Jul 9;13(1):235. doi: 10.1016/j.stemcr.2019.05.022. No abstract available.

12.

SANS study on the nano-crystalline network structure of elastic physical gels made of syndiotactic polypropylene.

Endo F, Kurokawa N, Tanimoto K, Iwase H, Maeda T, Hotta A.

Soft Matter. 2019 Jul 10;15(27):5521-5528. doi: 10.1039/c9sm00582j.

PMID:
31241635
13.

Protective effects of the Francisella tularensis ΔpdpC mutant against its virulent parental strain SCHU P9 in Cynomolgus macaques.

Tian D, Uda A, Ami Y, Hotta A, Park ES, Nagata N, Iwata-Yoshikawa N, Yamada A, Hirayama K, Miura K, Koyama Y, Azaki M, Morikawa S.

Sci Rep. 2019 Jun 24;9(1):9193. doi: 10.1038/s41598-019-45412-8.

14.

Thermo-Responsive Nanocomposite Hydrogels Based on PEG-b-PLGA Diblock Copolymer and Laponite.

Maeda T, Kitagawa M, Hotta A, Koizumi S.

Polymers (Basel). 2019 Feb 2;11(2). pii: E250. doi: 10.3390/polym11020250.

15.

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility.

Xu H, Wang B, Ono M, Kagita A, Fujii K, Sasakawa N, Ueda T, Gee P, Nishikawa M, Nomura M, Kitaoka F, Takahashi T, Okita K, Yoshida Y, Kaneko S, Hotta A.

Cell Stem Cell. 2019 Apr 4;24(4):566-578.e7. doi: 10.1016/j.stem.2019.02.005. Epub 2019 Mar 7.

PMID:
30853558
16.

MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.

Nakazeki F, Tsuge I, Horie T, Imamura K, Tsukita K, Hotta A, Baba O, Kuwabara Y, Nishino T, Nakao T, Nishiga M, Nishi H, Nakashima Y, Ide Y, Koyama S, Kimura M, Tsuji S, Naitoh M, Suzuki S, Izumi Y, Kawarai T, Kaji R, Kimura T, Inoue H, Ono K.

Clin Sci (Lond). 2019 Feb 22;133(4):583-595. doi: 10.1042/CS20180980. Print 2019 Feb 28.

PMID:
30777884
17.

In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids.

Korogi Y, Gotoh S, Ikeo S, Yamamoto Y, Sone N, Tamai K, Konishi S, Nagasaki T, Matsumoto H, Ito I, Chen-Yoshikawa TF, Date H, Hagiwara M, Asaka I, Hotta A, Mishima M, Hirai T.

Stem Cell Reports. 2019 Mar 5;12(3):431-440. doi: 10.1016/j.stemcr.2019.01.014. Epub 2019 Feb 14. Erratum in: Stem Cell Reports. 2019 Jul 9;13(1):235.

18.

Micropatterning of a 2-methacryloyloxyethyl phosphorylcholine polymer surface by hydrogenated amorphous carbon thin films for endothelialization and antithrombogenicity.

Bito K, Hasebe T, Maegawa S, Kitagawa T, Matsumoto T, Suzuki T, Hotta A.

Acta Biomater. 2019 Mar 15;87:187-196. doi: 10.1016/j.actbio.2019.01.059. Epub 2019 Jan 31.

PMID:
30710709
19.

The maximum dimension of the inferior vena cava is a significant predictor of postoperative mortality in lung cancer patients with idiopathic interstitial pneumonia.

Fukui M, Takamochi K, Suzuki K, Hotta A, Ando K, Matsunaga T, Oh S, Kawagoe I, Suzuki K.

Surg Today. 2019 Jun;49(6):467-473. doi: 10.1007/s00595-018-1757-1. Epub 2019 Jan 5.

PMID:
30612207
20.

Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy.

Minagawa A, Yoshikawa T, Yasukawa M, Hotta A, Kunitomo M, Iriguchi S, Takiguchi M, Kassai Y, Imai E, Yasui Y, Kawai Y, Zhang R, Uemura Y, Miyoshi H, Nakanishi M, Watanabe A, Hayashi A, Kawana K, Fujii T, Nakatsura T, Kaneko S.

Cell Stem Cell. 2018 Dec 6;23(6):850-858.e4. doi: 10.1016/j.stem.2018.10.005. Epub 2018 Nov 15.

21.

Relationship between occlusal force and condylar morphology in class II and III after bi-maxillary osteotomy.

Ueki K, Yoshizawa K, Moroi A, Tsutsui T, Hotta A, Hiraide R, Takayama A, Tsunoda T, Saito Y, Sato M, Baba N.

J Craniomaxillofac Surg. 2018 Dec;46(12):2103-2107. doi: 10.1016/j.jcms.2018.10.010. Epub 2018 Oct 22.

PMID:
30420148
22.

The homologous Arabidopsis MRS2/MGT/CorA-type Mg2+ channels, AtMRS2-10 and AtMRS2-1 exhibit different aluminum transport activity.

Ishijima S, Manabe Y, Shinkawa Y, Hotta A, Tokumasu A, Ida M, Sagami I.

Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2184-2191. doi: 10.1016/j.bbamem.2018.08.016. Epub 2018 Aug 31.

23.

Efficient mRNA delivery system utilizing chimeric VSVG-L7Ae virus-like particles.

Zhitnyuk Y, Gee P, Lung MSY, Sasakawa N, Xu H, Saito H, Hotta A.

Biochem Biophys Res Commun. 2018 Nov 10;505(4):1097-1102. doi: 10.1016/j.bbrc.2018.09.113. Epub 2018 Oct 10.

PMID:
30316514
24.

Association between Pulmonary Function and Stair-Climbing Test Results after Lung Resection: A Pilot Study.

Kubori Y, Matsuki R, Hotta A, Morisawa T, Tamaki A.

Can Respir J. 2018 Sep 9;2018:1925028. doi: 10.1155/2018/1925028. eCollection 2018.

25.

A β1-tubulin-based megakaryocyte maturation reporter system identifies novel drugs that promote platelet production.

Seo H, Chen SJ, Hashimoto K, Endo H, Nishi Y, Ohta A, Yamamoto T, Hotta A, Sawaguchi A, Hayashi H, Koseki N, Murphy GJ, Fukuda K, Sugimoto N, Eto K.

Blood Adv. 2018 Sep 11;2(17):2262-2272. doi: 10.1182/bloodadvances.2018019547.

26.

Restoration of Dystrophin Protein Expression by Exon Skipping Utilizing CRISPR-Cas9 in Myoblasts Derived from DMD Patient iPS Cells.

Ifuku M, Iwabuchi KA, Tanaka M, Lung MSY, Hotta A.

Methods Mol Biol. 2018;1828:191-217. doi: 10.1007/978-1-4939-8651-4_12.

PMID:
30171543
27.

A patient-derived iPSC model revealed oxidative stress increases facioscapulohumeral muscular dystrophy-causative DUX4.

Sasaki-Honda M, Jonouchi T, Arai M, Hotta A, Mitsuhashi S, Nishino I, Matsuda R, Sakurai H.

Hum Mol Genet. 2018 Dec 1;27(23):4024-4035. doi: 10.1093/hmg/ddy293.

28.

Mandibular bone healing after advancement or setback surgery using sagittal split ramus osteotomy.

Ueki K, Moroi A, Tsutsui T, Hotta A, Hiraide R, Takayama A, Tsunoda T, Saito Y, Sato M, Baba N, Yoshizawa K.

J Craniomaxillofac Surg. 2018 Sep;46(9):1500-1503. doi: 10.1016/j.jcms.2018.06.010. Epub 2018 Jun 13.

PMID:
30041994
29.

A Case of Euthyroid Graves' Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody.

Hotta A, Tanaka T, Kato H, Kakoi S, Shimizu Y, Hasegawa C, Hayakawa A, Yasuda S, Ogawa K, Ito S, Ohguchi H, Yagi T, Koyama H, Kawamura M, Sugitani K, Ogura Y, Joh T, Imaeda K.

Case Rep Endocrinol. 2018 Jun 13;2018:1707959. doi: 10.1155/2018/1707959. eCollection 2018.

30.

Reciprocal expression of Slug and Snail in human oral cancer cells.

Nakamura R, Ishii H, Endo K, Hotta A, Fujii E, Miyazawa K, Saitoh M.

PLoS One. 2018 Jul 3;13(7):e0199442. doi: 10.1371/journal.pone.0199442. eCollection 2018.

31.

Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress.

Honda-Ozaki F, Terashima M, Niwa A, Saiki N, Kawasaki Y, Ito H, Hotta A, Nagahashi A, Igura K, Asaka I, Li HL, Yanagimachi M, Furukawa F, Kanazawa N, Nakahata T, Saito MK.

Stem Cell Reports. 2018 Jun 5;10(6):1835-1850. doi: 10.1016/j.stemcr.2018.04.004. Epub 2018 May 3.

32.

Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs.

Ikeda T, Hikichi T, Miura H, Shibata H, Mitsunaga K, Yamada Y, Woltjen K, Miyamoto K, Hiratani I, Yamada Y, Hotta A, Yamamoto T, Okita K, Masui S.

Nat Commun. 2018 Apr 11;9(1):1387. doi: 10.1038/s41467-018-03748-1.

33.

An Autopsy Case of Pulmonary Tumor Thrombotic Microangiopathy Due to Rapidly Progressing Colon Cancer in a Patient with Type 2 Diabetes.

Ohguchi H, Imaeda K, Hotta A, Kakoi S, Yasuda S, Shimizu Y, Hayakawa A, Mishina H, Hasegawa C, Ito S, Ogawa K, Yagi T, Koyama H, Tanaka T, Kato H, Takahashi S, Joh T.

Intern Med. 2018 Sep 1;57(17):2533-2539. doi: 10.2169/internalmedicine.0204-17. Epub 2018 Mar 30.

34.

Time-course change in temporomandibular joint space after advancement and setback mandibular osteotomy with Le Fort I osteotomy.

Ueki K, Moroi A, Tsutsui T, Hiraide R, Takayama A, Saito Y, Sato M, Baba N, Tsunoda T, Hotta A, Yoshizawa K.

J Craniomaxillofac Surg. 2018 Apr;46(4):679-687. doi: 10.1016/j.jcms.2018.02.001. Epub 2018 Feb 9.

PMID:
29545032
35.

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors.

Oshima K, Saiki N, Tanaka M, Imamura H, Niwa A, Tanimura A, Nagahashi A, Hirayama A, Okita K, Hotta A, Kitayama S, Osawa M, Kaneko S, Watanabe A, Asaka I, Fujibuchi W, Imai K, Yabe H, Kamachi Y, Hara J, Kojima S, Tomita M, Soga T, Noma T, Nonoyama S, Nakahata T, Saito MK.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):719-725. doi: 10.1016/j.bbrc.2018.02.139. Epub 2018 Feb 17.

36.

Nanocomposite injectable gels capable of self-replenishing regenerative extracellular microenvironments for in vivo tissue engineering.

Nagahama K, Oyama N, Ono K, Hotta A, Kawauchi K, Nishikata T.

Biomater Sci. 2018 Feb 27;6(3):550-561. doi: 10.1039/c7bm01167a.

PMID:
29379910
37.

Site-specific randomization of the endogenous genome by a regulatable CRISPR-Cas9 piggyBac system in human cells.

Ishida K, Xu H, Sasakawa N, Lung MSY, Kudryashev JA, Gee P, Hotta A.

Sci Rep. 2018 Jan 10;8(1):310. doi: 10.1038/s41598-017-18568-4.

38.

Evaluation of Francisella tularensis ΔpdpC as a candidate live attenuated vaccine against respiratory challenge by a virulent SCHU P9 strain of Francisella tularensis in a C57BL/6J mouse model.

Tian D, Uda A, Park ES, Hotta A, Fujita O, Yamada A, Hirayama K, Hotta K, Koyama Y, Azaki M, Morikawa S.

Microbiol Immunol. 2018 Jan;62(1):24-33. doi: 10.1111/1348-0421.12555. Epub 2018 Jan 1.

39.

Comparison of temporomandibular joint and ramus morphology between class II and class III cases before and after bi-maxillary osteotomy.

Iguchi R, Yoshizawa K, Moroi A, Tsutsui T, Hotta A, Hiraide R, Takayama A, Tsunoda T, Saito Y, Sato M, Baba N, Ueki K.

J Craniomaxillofac Surg. 2017 Dec;45(12):2002-2009. doi: 10.1016/j.jcms.2017.09.018. Epub 2017 Sep 22.

PMID:
29046240
40.

Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells.

Kojima Y, Sasaki K, Yokobayashi S, Sakai Y, Nakamura T, Yabuta Y, Nakaki F, Nagaoka S, Woltjen K, Hotta A, Yamamoto T, Saitou M.

Cell Stem Cell. 2017 Oct 5;21(4):517-532.e5. doi: 10.1016/j.stem.2017.09.005.

41.

Modified hybrid fixation using absorbable plate and screw for mandibular advancement surgery.

Ueki K, Yoshizawa K, Moroi A, Hotta A, Tsutsui T, Fukaya K, Hiraide R, Takayama A, Tsunoda T, Saito Y, Baba N, Sato M.

J Craniomaxillofac Surg. 2017 Nov;45(11):1788-1793. doi: 10.1016/j.jcms.2017.08.006. Epub 2017 Aug 10.

PMID:
28927955
42.

In vitro basic fibroblast growth factor (bFGF) delivery using an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coated with a micropatterned diamond-like carbon (DLC) film.

Bito K, Hasebe T, Maegawa S, Maeda T, Matsumoto T, Suzuki T, Hotta A.

J Biomed Mater Res A. 2017 Dec;105(12):3384-3391. doi: 10.1002/jbm.a.36201. Epub 2017 Sep 23.

PMID:
28869709
43.

Change in lip closing force in Classes II and III malocclusion before and after sagittal split ramus osteotomy with Le Fort I osteotomy.

Tsutsui T, Yoshizawa K, Moroi A, Hotta A, Fukaya K, Hiraide R, Takayama A, Tsunoda T, Saito Y, Iguchi R, Kosaka A, Ikawa H, Ueki K.

J Craniomaxillofac Surg. 2017 Sep;45(9):1415-1418. doi: 10.1016/j.jcms.2017.06.026. Epub 2017 Jul 8.

PMID:
28754365
44.

Cellular Reprogramming, Genome Editing, and Alternative CRISPR Cas9 Technologies for Precise Gene Therapy of Duchenne Muscular Dystrophy.

Gee P, Xu H, Hotta A.

Stem Cells Int. 2017;2017:8765154. doi: 10.1155/2017/8765154. Epub 2017 May 15. Review.

45.

Comparison between stair-climbing test and six-minute walk test after lung resection using video-assisted thoracoscopic surgery lobectomy.

Kubori Y, Matsuki R, Hotta A, Morisawa T, Tamaki A.

J Phys Ther Sci. 2017 May;29(5):902-904. doi: 10.1589/jpts.29.902. Epub 2017 May 16.

46.

Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape.

Chen Z, Chang WY, Etheridge A, Strickfaden H, Jin Z, Palidwor G, Cho JH, Wang K, Kwon SY, Doré C, Raymond A, Hotta A, Ellis J, Kandel RA, Dilworth FJ, Perkins TJ, Hendzel MJ, Galas DJ, Stanford WL.

Aging Cell. 2017 Aug;16(4):870-887. doi: 10.1111/acel.12621. Epub 2017 Jun 8.

47.

Pluripotent stem cell models of Blau syndrome reveal an IFN-γ-dependent inflammatory response in macrophages.

Takada S, Kambe N, Kawasaki Y, Niwa A, Honda-Ozaki F, Kobayashi K, Osawa M, Nagahashi A, Semi K, Hotta A, Asaka I, Yamada Y, Nishikomori R, Heike T, Matsue H, Nakahata T, Saito MK.

J Allergy Clin Immunol. 2018 Jan;141(1):339-349.e11. doi: 10.1016/j.jaci.2017.04.013. Epub 2017 Jun 3.

PMID:
28587749
48.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H.

Sci Transl Med. 2017 May 24;9(391). pii: eaaf3962. doi: 10.1126/scitranslmed.aaf3962.

49.

Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch.

Hirosawa M, Fujita Y, Parr CJC, Hayashi K, Kashida S, Hotta A, Woltjen K, Saito H.

Nucleic Acids Res. 2017 Jul 27;45(13):e118. doi: 10.1093/nar/gkx309.

50.

Allergic contact dermatitis caused by diethyl thiourea in a neoprene-containing wet suit.

Okawa T, Hotta A, Sato M, Takahashi S, Komori J, Aihara M.

J Dermatol. 2018 Mar;45(3):365-366. doi: 10.1111/1346-8138.13873. Epub 2017 Apr 22. No abstract available.

PMID:
28432694

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