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Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans.

P JG, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S.

PLoS Negl Trop Dis. 2019 Sep 16;13(9):e0007730. doi: 10.1371/journal.pntd.0007730. [Epub ahead of print]


A phase 1 study of the safety, reactogenicity, and immunogenicity of a Schistosoma mansoni vaccine with or without glucopyranosyl lipid A aqueous formulation (GLA-AF) in healthy adults from a non-endemic area.

Keitel WA, Potter GE, Diemert D, Bethony J, El Sahly HM, Kennedy JK, Patel SM, Plieskatt JL, Jones W, Deye G, Bottazzi ME, Hotez PJ, Atmar RL.

Vaccine. 2019 Sep 9. pii: S0264-410X(19)31151-X. doi: 10.1016/j.vaccine.2019.08.075. [Epub ahead of print]


Response to `letter to the editor: 'Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America'´.

Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J.

Expert Rev Anti Infect Ther. 2019 Aug 6:1-3. doi: 10.1080/14787210.2019.1649139. [Epub ahead of print] No abstract available.


Globalists versus nationalists: Bridging the divide through blue marble health.

Hotez PJ.

PLoS Negl Trop Dis. 2019 Jul 11;13(7):e0007156. doi: 10.1371/journal.pntd.0007156. eCollection 2019 Jul. No abstract available.


In Search of Congenital Chagas Disease in the Sierra Nevada de Santa Marta, Colombia.

Parra-Henao G, Oliveros H, Hotez PJ, Motoa G, Franco-Paredes C, Henao-Martínez AF.

Am J Trop Med Hyg. 2019 Sep;101(3):482-483. doi: 10.4269/ajtmh.19-0110.


"Running the Gauntlet": Formidable challenges in advancing neglected tropical diseases vaccines from development through licensure, and a "Call to Action".

Bottazzi ME, Hotez PJ.

Hum Vaccin Immunother. 2019 Jul 10:1-8. doi: 10.1080/21645515.2019.1629254. [Epub ahead of print]


The public health control of scabies: priorities for research and action.

Engelman D, Cantey PT, Marks M, Solomon AW, Chang AY, Chosidow O, Enbiale W, Engels D, Hay RJ, Hendrickx D, Hotez PJ, Kaldor JM, Kama M, Mackenzie CD, McCarthy JS, Martin DL, Mengistu B, Maurer T, Negussu N, Romani L, Sokana O, Whitfeld MJ, Fuller LC, Steer AC.

Lancet. 2019 Jul 6;394(10192):81-92. doi: 10.1016/S0140-6736(19)31136-5. Epub 2019 Jun 6. Review.


Science tikkun: A framework embracing the right of access to innovation and translational medicine on a global scale.

Hotez PJ.

PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007117. doi: 10.1371/journal.pntd.0007117. eCollection 2019 Jun. No abstract available.


Transmission-Blocking Vaccines for Malaria: Time to Talk about Vaccine Introduction.

Coelho CH, Rappuoli R, Hotez PJ, Duffy PE.

Trends Parasitol. 2019 Jul;35(7):483-486. doi: 10.1016/ Epub 2019 May 29.


A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection.

Barry MA, Versteeg L, Wang Q, Pollet J, Zhan B, Gusovsky F, Bottazzi ME, Hotez PJ, Jones KM.

PLoS Negl Trop Dis. 2019 May 30;13(5):e0007413. doi: 10.1371/journal.pntd.0007413. eCollection 2019 May.


Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients.

Bartsch SM, Bottazzi ME, Asti L, Strych U, Meymandi S, Falcón-Lezama JA, Randall S, Hotez PJ, Lee BY.

Vaccine. 2019 Jun 19;37(28):3704-3714. doi: 10.1016/j.vaccine.2019.05.028. Epub 2019 May 16.


Pediatric tropical medicine: The neglected diseases of children.

Hotez PJ, Odom John AR, LaBeaud AD.

PLoS Negl Trop Dis. 2019 May 9;13(5):e0007008. doi: 10.1371/journal.pntd.0007008. eCollection 2019 May. No abstract available.


Collateral Benefits of Preventive Chemotherapy - Expanding the War on Neglected Tropical Diseases.

Hotez PJ, Fenwick A, Molyneux DH.

N Engl J Med. 2019 Jun 20;380(25):2389-2391. doi: 10.1056/NEJMp1900400. Epub 2019 May 8. No abstract available.


Immunizations and vaccines: a decade of successes and reversals, and a call for 'vaccine diplomacy'.

Hotez PJ.

Int Health. 2019 Sep 2;11(5):331-333. doi: 10.1093/inthealth/ihz024.


Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women.

Hotez PJ, Harrison W, Fenwick A, Bustinduy AL, Ducker C, Sabina Mbabazi P, Engels D, Floerecke Kjetland E.

PLoS Negl Trop Dis. 2019 Apr 4;13(4):e0007025. doi: 10.1371/journal.pntd.0007025. eCollection 2019 Apr. No abstract available.


Linking Tropical Infections to Hypertension: New Comorbid Disease Paradigms in Our Era of "Blue Marble Health".

Hotez PJ.

J Am Heart Assoc. 2019 Mar 19;8(6):e03984. doi: 10.1161/JAHA.119.012313.


Resolving "worm wars": An extended comparison review of findings from key economics and epidemiological studies.

Majid MF, Kang SJ, Hotez PJ.

PLoS Negl Trop Dis. 2019 Mar 7;13(3):e0006940. doi: 10.1371/journal.pntd.0006940. eCollection 2019 Mar. Review. No abstract available.


Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region.

Grillet ME, Hernández-Villena JV, Llewellyn MS, Paniz-Mondolfi AE, Tami A, Vincenti-Gonzalez MF, Marquez M, Mogollon-Mendoza AC, Hernandez-Pereira CE, Plaza-Morr JD, Blohm G, Grijalva MJ, Costales JA, Ferguson HM, Schwabl P, Hernandez-Castro LE, Lamberton PHL, Streicker DG, Haydon DT, Miles MA, Acosta-Serrano A, Acquattela H, Basañez MG, Benaim G, Colmenares LA, Conn JE, Espinoza R, Freilij H, Graterol-Gil MC, Hotez PJ, Kato H, Lednicky JA, Martinez CE, Mas-Coma S, Morris JG Jr, Navarro JC, Ramirez JL, Rodriguez M, Urbina JA, Villegas L, Segovia MJ, Carrasco HJ, Crainey JL, Luz SLB, Moreno JD, Noya Gonzalez OO, Ramírez JD, Alarcón-de Noya B.

Lancet Infect Dis. 2019 May;19(5):e149-e161. doi: 10.1016/S1473-3099(18)30757-6. Epub 2019 Feb 21. Review. Erratum in: Lancet Infect Dis. 2019 Feb 27;:.


Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America.

Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J.

Expert Rev Anti Infect Ther. 2019 Mar;17(3):145-157. doi: 10.1080/14787210.2019.1577731. Epub 2019 Feb 13. Review.


Resurgence of Vaccine-Preventable Diseases in Venezuela as a Regional Public Health Threat in the Americas.

Paniz-Mondolfi AE, Tami A, Grillet ME, Márquez M, Hernández-Villena J, Escalona-Rodríguez MA, Blohm GM, Mejías I, Urbina-Medina H, Rísquez A, Castro J, Carvajal A, Walter C, López MG, Schwabl P, Hernández-Castro L, Miles MA, Hotez PJ, Lednicky J, Morris JG Jr, Crainey J, Luz S, Ramírez JD, Sordillo E, Llewellyn M, Canache M, Araque M, Oletta J.

Emerg Infect Dis. 2019 Apr;25(4):625-632. doi: 10.3201/eid2504.181305. Epub 2019 Apr 17.


Neglected tropical diseases in children: An assessment of gaps in research prioritization.

Rees CA, Hotez PJ, Monuteaux MC, Niescierenko M, Bourgeois FT.

PLoS Negl Trop Dis. 2019 Jan 29;13(1):e0007111. doi: 10.1371/journal.pntd.0007111. eCollection 2019 Jan.


China's shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative.

Wang L, Zou Y, Zhu X, Bottazzi ME, Hotez PJ, Zhan B.

PLoS Negl Trop Dis. 2019 Jan 24;13(1):e0006946. doi: 10.1371/journal.pntd.0006946. eCollection 2019 Jan. No abstract available.


Ghana: Accelerating neglected tropical disease control in a setting of economic development.

Hotez PJ, Biritwum NK, Fenwick A, Molyneux DH, Sachs JD.

PLoS Negl Trop Dis. 2019 Jan 17;13(1):e0007005. doi: 10.1371/journal.pntd.0007005. eCollection 2019 Jan. No abstract available.


What Is the Value of Different Zika Vaccination Strategies to Prevent and Mitigate Zika Outbreaks?

Bartsch SM, Asti L, Cox SN, Durham DP, Randall S, Hotez PJ, Galvani AP, Lee BY.

J Infect Dis. 2019 Aug 9;220(6):920-931. doi: 10.1093/infdis/jiy688.


IgG Induced by Vaccination With Ascaris suum Extracts Is Protective Against Infection.

Gazzinelli-Guimarães AC, Gazzinelli-Guimarães PH, Nogueira DS, Oliveira FMS, Barbosa FS, Amorim CCO, Cardoso MS, Kraemer L, Caliari MV, Akamatsu MA, Ho PL, Jones KM, Weatherhead J, Bottazzi ME, Hotez PJ, Zhan B, Bartholomeu DC, Russo RC, Bueno LL, Fujiwara RT.

Front Immunol. 2018 Nov 9;9:2535. doi: 10.3389/fimmu.2018.02535. eCollection 2018.


Advancing the Development of a Human Schistosomiasis Vaccine.

Hotez PJ, Bottazzi ME, Bethony J, Diemert DD.

Trends Parasitol. 2019 Feb;35(2):104-108. doi: 10.1016/ Epub 2018 Nov 16.


Pakistan: A nation held back by NTDs.

Blum AJ, Majid MF, Hotez PJ.

PLoS Negl Trop Dis. 2018 Oct 18;12(10):e0006751. doi: 10.1371/journal.pntd.0006751. eCollection 2018 Oct. No abstract available.


Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.

Zhan B, Arumugam S, Kennedy MW, Tricoche N, Lian LY, Asojo OA, Bennuru S, Bottazzi ME, Hotez PJ, Lustigman S, Klei TR.

PLoS Negl Trop Dis. 2018 Oct 8;12(10):e0006772. doi: 10.1371/journal.pntd.0006772. eCollection 2018 Oct.


Crafting your scientist brand.

Hotez PJ.

PLoS Biol. 2018 Oct 5;16(10):e3000024. doi: 10.1371/journal.pbio.3000024. eCollection 2018 Oct.


Ascaris Larval Infection and Lung Invasion Directly Induce Severe Allergic Airway Disease in Mice.

Weatherhead JE, Porter P, Coffey A, Haydel D, Versteeg L, Zhan B, Gazzinelli Guimarães AC, Fujiwara R, Jaramillo AM, Bottazzi ME, Hotez PJ, Corry DB, Beaumier CM.

Infect Immun. 2018 Nov 20;86(12). pii: e00533-18. doi: 10.1128/IAI.00533-18. Print 2018 Dec.


The rise of leishmaniasis in the twenty-first century.

Hotez PJ.

Trans R Soc Trop Med Hyg. 2018 Sep 1;112(9):421-422. doi: 10.1093/trstmh/try075. No abstract available.


Minutes to midnight: Turning back the Doomsday Clock through neglected disease vaccine diplomacy.

Hotez PJ.

PLoS Negl Trop Dis. 2018 Sep 20;12(9):e0006676. doi: 10.1371/journal.pntd.0006676. eCollection 2018 Sep. No abstract available.


Science in the fight to uphold the rights of children.

Caplan AL, Hotez PJ.

PLoS Biol. 2018 Sep 18;16(9):e3000010. doi: 10.1371/journal.pbio.3000010. eCollection 2018 Sep.


Vaccines Hesitancy and the Dermatologist.

Hotez PJ, Wolf JE.

Skinmed. 2018 Jul 1;16(4):219-221. eCollection 2018.


Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice.

de la Cruz JJ, Villanueva-Lizama L, Dzul-Huchim V, Ramírez-Sierra MJ, Martinez-Vega P, Rosado-Vallado M, Ortega-Lopez J, Flores-Pucheta CI, Gillespie P, Zhan B, Bottazzi ME, Hotez PJ, Dumonteil E.

Hum Vaccin Immunother. 2019;15(1):210-219. doi: 10.1080/21645515.2018.1520581. Epub 2018 Sep 21.


Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm.

Briggs N, Wei J, Versteeg L, Zhan B, Keegan B, Damania A, Pollet J, Hayes KS, Beaumier C, Seid CA, Leong J, Grencis RK, Bottazzi ME, Sastry KJ, Hotez PJ.

PLoS Pathog. 2018 Aug 28;14(8):e1007273. doi: 10.1371/journal.ppat.1007273. eCollection 2018 Aug.


Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production.

Gunter SM, Versteeg L, Jones KM, Keegan BP, Strych U, Bottazzi ME, Hotez PJ, Brown EL.

Parasite Immunol. 2018 Nov;40(11):e12585. doi: 10.1111/pim.12585. Epub 2018 Sep 24.


Hajj, Umrah, and the neglected tropical diseases.

Almutairi MM, Alsalem WS, Hassanain M, Hotez PJ.

PLoS Negl Trop Dis. 2018 Aug 16;12(8):e0006539. doi: 10.1371/journal.pntd.0006539. eCollection 2018 Aug. No abstract available.


Lessons along the Critical Path: Developing Vaccines against Human Helminths.

Diemert DJ, Bottazzi ME, Plieskatt J, Hotez PJ, Bethony JM.

Trends Parasitol. 2018 Sep;34(9):747-758. doi: 10.1016/ Epub 2018 Jul 28. Review.


Advancing biological therapies against a rising tide of American anti-science and other external threats.

Hotez PJ.

Expert Opin Biol Ther. 2018 Jul;18(sup1):5-7. doi: 10.1080/14712598.2018.1478963. No abstract available.


Global "worming": Climate change and its projected general impact on human helminth infections.

Blum AJ, Hotez PJ.

PLoS Negl Trop Dis. 2018 Jul 19;12(7):e0006370. doi: 10.1371/journal.pntd.0006370. eCollection 2018 Jul. No abstract available.


Correction: The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties.

Olive JK, Hotez PJ, Damania A, Nolan MS.

PLoS Med. 2018 Jul 6;15(7):e1002616. doi: 10.1371/journal.pmed.1002616. eCollection 2018 Jul.


Extending the global worm index and its links to human development and child education.

Kang S, Damania A, Majid MF, Hotez PJ.

PLoS Negl Trop Dis. 2018 Jun 21;12(6):e0006322. doi: 10.1371/journal.pntd.0006322. eCollection 2018 Jun. No abstract available.


The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties.

Olive JK, Hotez PJ, Damania A, Nolan MS.

PLoS Med. 2018 Jun 12;15(6):e1002578. doi: 10.1371/journal.pmed.1002578. eCollection 2018 Jun. Erratum in: PLoS Med. 2018 Jul 6;15(7):e1002616.


"Rapid impact" 10 years after: The first "decade" (2006-2016) of integrated neglected tropical disease control.

Hotez PJ, Fenwick A, Ray SE, Hay SI, Molyneux DH.

PLoS Negl Trop Dis. 2018 May 24;12(5):e0006137. doi: 10.1371/journal.pntd.0006137. eCollection 2018 May. No abstract available.


Human Parasitology and Parasitic Diseases: Heading Towards 2050.

Hotez PJ.

Adv Parasitol. 2018;100:29-38. doi: 10.1016/bs.apar.2018.03.002. Epub 2018 Apr 5.


Could violent conflict derail the London Declaration on NTDs?

Du RY, Stanaway JD, Hotez PJ.

PLoS Negl Trop Dis. 2018 Apr 19;12(4):e0006136. doi: 10.1371/journal.pntd.0006136. eCollection 2018 Apr. No abstract available.


Empowering Girls and Women through Hookworm Prevention.

Hotez PJ.

Am J Trop Med Hyg. 2018 May;98(5):1211-1212. doi: 10.4269/ajtmh.17-0934. Epub 2018 Jan 11. No abstract available.


India's neglected tropical diseases.

Hotez PJ, Damania A.

PLoS Negl Trop Dis. 2018 Mar 22;12(3):e0006038. doi: 10.1371/journal.pntd.0006038. eCollection 2018 Mar. No abstract available.


Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen.

Nyon MP, Du L, Tseng CK, Seid CA, Pollet J, Naceanceno KS, Agrawal A, Algaissi A, Peng BH, Tai W, Jiang S, Bottazzi ME, Strych U, Hotez PJ.

Vaccine. 2018 Mar 27;36(14):1853-1862. doi: 10.1016/j.vaccine.2018.02.065. Epub 2018 Feb 26.

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