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Items: 38


A novel form of JARID2 is required for differentiation in lineage-committed cells.

Al-Raawi D, Jones R, Wijesinghe S, Halsall J, Petric M, Roberts S, Hotchin NA, Kanhere A.

EMBO J. 2019 Feb 1;38(3). pii: e98449. doi: 10.15252/embj.201798449. Epub 2018 Dec 20.


Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration.

Sarhan AR, Szyroka J, Begum S, Tomlinson MG, Hotchin NA, Heath JK, Cunningham DL.

Sci Rep. 2017 Jun 21;7(1):3970. doi: 10.1038/s41598-017-04015-x.


LAR protein tyrosine phosphatase regulates focal adhesions through CDK1.

Sarhan AR, Patel TR, Cowell AR, Tomlinson MG, Hellberg C, Heath JK, Cunningham DL, Hotchin NA.

J Cell Sci. 2016 Aug 1;129(15):2962-71. doi: 10.1242/jcs.191379. Epub 2016 Jun 27.


Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study.

Sarhan AR, Patel TR, Creese AJ, Tomlinson MG, Hellberg C, Heath JK, Hotchin NA, Cunningham DL.

Mol Cell Proteomics. 2016 Jun;15(6):1823-36. doi: 10.1074/mcp.M115.053652. Epub 2016 Apr 13.


Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer.

Clarke K, Daubon T, Turan N, Soulet F, Mohd Zahari M, Ryan KR, Durant S, He S, Herbert J, Ankers J, Heath JK, Bjerkvig R, Bicknell R, Hotchin NA, Bikfalvi A, Falciani F.

PLoS Genet. 2015 Jul 1;11(7):e1005325. doi: 10.1371/journal.pgen.1005325. eCollection 2015 Jul.


Electroporation and microinjection successfully deliver single-stranded and duplex DNA into live cells as detected by FRET measurements.

Bamford RA, Zhao ZY, Hotchin NA, Styles IB, Nash GB, Tucker JH, Bicknell R.

PLoS One. 2014 Apr 22;9(4):e95097. doi: 10.1371/journal.pone.0095097. eCollection 2014.


Regulator of G-Protein Signalling-14 (RGS14) Regulates the Activation of αMβ2 Integrin during Phagocytosis.

Lim J, Thompson J, May RC, Hotchin NA, Caron E.

PLoS One. 2013 Jun 21;8(6):e69163. doi: 10.1371/journal.pone.0069163. Print 2013.


α3β1 integrins regulate CD151 complex assembly and membrane dynamics in carcinoma cells within 3D environments.

Scales TM, Jayo A, Obara B, Holt MR, Hotchin NA, Berditchevski F, Parsons M.

Oncogene. 2013 Aug 22;32(34):3965-79. doi: 10.1038/onc.2012.415. Epub 2012 Sep 17.


Signalling mechanisms of the leukocyte integrin αMβ2: current and future perspectives.

Lim J, Hotchin NA.

Biol Cell. 2012 Nov;104(11):631-40. doi: 10.1111/boc.201200013. Epub 2012 Aug 24. Review.


Plakoglobin-dependent regulation of keratinocyte apoptosis by Rnd3.

Ryan KR, Lock FE, Heath JK, Hotchin NA.

J Cell Sci. 2012 Jul 1;125(Pt 13):3202-9. doi: 10.1242/jcs.101931. Epub 2012 Mar 27.


Differential regulation of adhesion complex turnover by ROCK1 and ROCK2.

Lock FE, Ryan KR, Poulter NS, Parsons M, Hotchin NA.

PLoS One. 2012;7(2):e31423. doi: 10.1371/journal.pone.0031423. Epub 2012 Feb 13.


Ser756 of β2 integrin controls Rap1 activity during inside-out activation of αMβ2.

Lim J, Hotchin NA, Caron E.

Biochem J. 2011 Aug 1;437(3):461-7. doi: 10.1042/BJ20101666.


Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation.

Lock FE, Hotchin NA.

PLoS One. 2009 Dec 4;4(12):e8190. doi: 10.1371/journal.pone.0008190.


Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma.

Jethwa P, Naqvi M, Hardy RG, Hotchin NA, Roberts S, Spychal R, Tselepis C.

World J Gastroenterol. 2008 Feb 21;14(7):1044-52.


A role for iron in Wnt signalling.

Brookes MJ, Boult J, Roberts K, Cooper BT, Hotchin NA, Matthews G, Iqbal T, Tselepis C.

Oncogene. 2008 Feb 7;27(7):966-75. Epub 2007 Aug 13.


Syntenin-1 is a new component of tetraspanin-enriched microdomains: mechanisms and consequences of the interaction of syntenin-1 with CD63.

Latysheva N, Muratov G, Rajesh S, Padgett M, Hotchin NA, Overduin M, Berditchevski F.

Mol Cell Biol. 2006 Oct;26(20):7707-18. Epub 2006 Aug 14.


Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes.

Turner FE, Broad S, Khanim FL, Jeanes A, Talma S, Hughes S, Tselepis C, Hotchin NA.

J Biol Chem. 2006 Jul 28;281(30):21321-31. Epub 2006 May 17.


Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway.

McMullan R, Lax S, Robertson VH, Radford DJ, Broad S, Watt FM, Rowles A, Croft DR, Olson MF, Hotchin NA.

Curr Biol. 2003 Dec 16;13(24):2185-9.


The tetraspanin CD151 functions as a negative regulator in the adhesion-dependent activation of Ras.

Sawada S, Yoshimoto M, Odintsova E, Hotchin NA, Berditchevski F.

J Biol Chem. 2003 Jul 18;278(29):26323-6. Epub 2003 Jun 2.


RAC1 regulates adherens junctions through endocytosis of E-cadherin.

Akhtar N, Hotchin NA.

Mol Biol Cell. 2001 Apr;12(4):847-62.


Co-localization of Rac1 and E-cadherin in human epidermal keratinocytes.

Akhtar N, Hudson KR, Hotchin NA.

Cell Adhes Commun. 2000;7(6):465-76.


Visualizing muscle cell migration in situ.

Knight B, Laukaitis C, Akhtar N, Hotchin NA, Edlund M, Horwitz AR.

Curr Biol. 2000 May 18;10(10):576-85.


Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase.

Hotchin NA, Cover TL, Akhtar N.

J Biol Chem. 2000 May 12;275(19):14009-12.


Differential activation of focal adhesion kinase, Rho and Rac by the ninth and tenth FIII domains of fibronectin.

Hotchin NA, Kidd AG, Altroff H, Mardon HJ.

J Cell Sci. 1999 Sep;112 (Pt 17):2937-46.


The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts.

Braga VM, Machesky LM, Hall A, Hotchin NA.

J Cell Biol. 1997 Jun 16;137(6):1421-31.


Regulation of cell surface beta 1 integrin levels during keratinocyte terminal differentiation.

Hotchin NA, Gandarillas A, Watt FM.

J Cell Biol. 1995 Mar;128(6):1209-19.


Regulation of keratinocyte terminal differentiation by integrin-extracellular matrix interactions.

Watt FM, Kubler MD, Hotchin NA, Nicholson LJ, Adams JC.

J Cell Sci. 1993 Sep;106 ( Pt 1):175-82.


Analysis of the tumorigenic potential of common marmoset lymphoblastoid cells expressing a constitutively activated c-myc gene.

Hotchin NA, Wedderburn N, Roberts I, Thomas JA, Bungey JA, Naylor B, Crawford DH.

Br J Cancer. 1993 May;67(5):926-32.


Kalinin, epiligrin and GB3 antigen: kalinepiligrinin-3?

Watt FM, Hotchin NA.

Curr Biol. 1992 Feb;2(2):106-7. No abstract available.


Immunohistology of Epstein-Barr virus-associated antigens in B cell disorders from immunocompromised individuals.

Thomas JA, Hotchin NA, Allday MJ, Amlot P, Rose M, Yacoub M, Crawford DH.

Transplantation. 1990 May;49(5):944-53.


Active Epstein-Barr virus infection in post-viral fatigue syndrome.

Hotchin NA, Read R, Smith DG, Crawford DH.

J Infect. 1989 Mar;18(2):143-50.


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