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Items: 16


RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?

Hosur V, Farley ML, Low BE, Burzenski LM, Shultz LD, Wiles MV.

Front Genet. 2018 Jul 4;9:233. doi: 10.3389/fgene.2018.00233. eCollection 2018.


ADAM17 is essential for ectodomain shedding of the EGF-receptor ligand amphiregulin.

Hosur V, Farley ML, Burzenski LM, Shultz LD, Wiles MV.

FEBS Open Bio. 2018 Mar 12;8(4):702-710. doi: 10.1002/2211-5463.12407. eCollection 2018 Apr.


Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.

Hosur V, Lyons BL, Burzenski LM, Shultz LD.

BMC Res Notes. 2017 Nov 7;10(1):573. doi: 10.1186/s13104-017-2899-8.


Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.

Hosur V, Low BE, Shultz LD, Wiles MV.

Biol Open. 2017 Aug 15;6(8):1174-1179. doi: 10.1242/bio.026260.


Development of Humanized Mice in the Age of Genome Editing.

Hosur V, Low BE, Avery C, Shultz LD, Wiles MV.

J Cell Biochem. 2017 Oct;118(10):3043-3048. doi: 10.1002/jcb.26002. Epub 2017 May 15.


Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing.

Hosur V, Burzenski LM, Stearns TM, Farley ML, Sundberg JP, Wiles MV, Shultz LD.

Exp Mol Pathol. 2017 Apr;102(2):337-346. doi: 10.1016/j.yexmp.2017.03.003. Epub 2017 Mar 6.


A little-known relationship between immune recovery syndrome and herpes zoster.

Bhandage S, Kurki M, Hosur V, Sukhija P, Bajoria A.

J Korean Assoc Oral Maxillofac Surg. 2016 Jun;42(3):169-72. doi: 10.5125/jkaoms.2016.42.3.169. Epub 2016 Jun 27.


Human cancer growth and therapy in immunodeficient mouse models.

Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL.

Cold Spring Harb Protoc. 2014 Jul 1;2014(7):694-708. doi: 10.1101/pdb.top073585. Review.


Subcapsular transplantation of tissue in the kidney.

Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL.

Cold Spring Harb Protoc. 2014 Jul 1;2014(7):737-40. doi: 10.1101/pdb.prot078089.


Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.

Hosur V, Johnson KR, Burzenski LM, Stearns TM, Maser RS, Shultz LD.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2200-9. doi: 10.1073/pnas.1323908111. Epub 2014 May 13.


Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice.

Hosur V, Cox ML, Burzenski LM, Riding RL, Alley L, Lyons BL, Kavirayani A, Martin KA, Cox GA, Johnson KR, Shultz LD.

PLoS One. 2013;8(1):e53426. doi: 10.1371/journal.pone.0053426. Epub 2013 Jan 2.


Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma.

Hosur V, Kavirayani A, Riefler J, Carney LM, Lyons B, Gott B, Cox GA, Shultz LD.

Cancer Genet. 2012 May;205(5):232-41. doi: 10.1016/j.cancergen.2012.03.005.


Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF.

Brehm MA, Racki WJ, Leif J, Burzenski L, Hosur V, Wetmore A, Gott B, Herlihy M, Ignotz R, Dunn R, Shultz LD, Greiner DL.

Blood. 2012 Mar 22;119(12):2778-88. doi: 10.1182/blood-2011-05-353243. Epub 2012 Jan 12.


Humanized mice for the study of type 1 and type 2 diabetes.

Greiner DL, Brehm MA, Hosur V, Harlan DM, Powers AC, Shultz LD.

Ann N Y Acad Sci. 2011 Dec;1245:55-8. doi: 10.1111/j.1749-6632.2011.06318.x.


Gene regulation of alpha4beta2 nicotinic receptors: microarray analysis of nicotine-induced receptor up-regulation and anti-inflammatory effects.

Hosur V, Leppanen S, Abutaha A, Loring RH.

J Neurochem. 2009 Nov;111(3):848-58. doi: 10.1111/j.1471-4159.2009.06373.x. Epub 2009 Sep 1.

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