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Effects of Sodium Bicarbonate in CKD Stages 3 and 4: A Randomized, Placebo-Controlled, Multicenter Clinical Trial.

Melamed ML, Horwitz EJ, Dobre MA, Abramowitz MK, Zhang L, Lo Y, Mitch WE, Hostetter TH.

Am J Kidney Dis. 2019 Nov 5. pii: S0272-6386(19)30945-X. doi: 10.1053/j.ajkd.2019.07.016. [Epub ahead of print]


Glomerular Filtration: Too Much of a Good Thing?

Mottl AK, Hostetter TH, Derebail VK.

Am J Kidney Dis. 2019 Jun;73(6):756-758. doi: 10.1053/j.ajkd.2019.01.039. No abstract available.


Contribution of 'clinically negligible' residual kidney function to clearance of uremic solutes.

Toth-Manikowski SM, Sirich TL, Meyer TW, Hostetter TH, Hwang S, Plummer NS, Hai X, Coresh J, Powe NR, Shafi T.

Nephrol Dial Transplant. 2019 Mar 15. pii: gfz042. doi: 10.1093/ndt/gfz042. [Epub ahead of print]


Effect of continuous venovenous haemodialysis on outcome and pharmacokinetics of arsenic species in a patient with acute promyelocytic leukaemia and acute kidney injury.

Gao C, Fan S, Hostetter TH, Wang W, Li J, Guo M, Zhou J, Hai X.

Br J Clin Pharmacol. 2019 Apr;85(4):849-853. doi: 10.1111/bcp.13875. Epub 2019 Feb 14.


Assessing Clinical Relevance of Uremic Toxins.

Flythe JE, Hostetter TH.

Clin J Am Soc Nephrol. 2019 Feb 7;14(2):182-183. doi: 10.2215/CJN.14931218. Epub 2019 Jan 21. No abstract available.


Metabolic Changes with Base-Loading in CKD.

Scialla JJ, Brown L, Gurley S, Corcoran DL, Bain JR, Muehlbauer MJ, O'Neal SK, M O'Connell T, Wolf M, Melamed ML, Hostetter TH, Abramowitz MK.

Clin J Am Soc Nephrol. 2018 Aug 7;13(8):1244-1246. doi: 10.2215/CJN.01830218. Epub 2018 Jun 22. No abstract available.


Serum Bicarbonate Concentration and Cognitive Function in Hypertensive Adults.

Dobre M, Gaussoin SA, Bates JT, Chonchol MB, Cohen DL, Hostetter TH, Raphael KL, Taylor AA, Lerner AJ, Wright JT Jr, Rahman M; SPRINT Research Group.

Clin J Am Soc Nephrol. 2018 Apr 6;13(4):596-603. doi: 10.2215/CJN.07050717. Epub 2018 Mar 22.


Editorial Note: From Both Sides Now.

Briggs JP, Hostetter TH.

J Am Soc Nephrol. 2018 Feb;29(2):355-356. doi: 10.1681/ASN.2017121322. Epub 2018 Jan 25. No abstract available.


Association between Urine Ammonium and Urine TGF-β1 in CKD.

Raphael KL, Gilligan S, Hostetter TH, Greene T, Beddhu S.

Clin J Am Soc Nephrol. 2018 Feb 7;13(2):223-230. doi: 10.2215/CJN.07510717. Epub 2017 Nov 16.


Single-Nephron Glomerular Filtration Rate in Healthy Adults.

Rosenberg ME, Hostetter TH.

N Engl J Med. 2017 Sep 21;377(12):1202-3. doi: 10.1056/NEJMc1709128. No abstract available.


Results of the HEMO Study suggest that p-cresol sulfate and indoxyl sulfate are not associated with cardiovascular outcomes.

Shafi T, Sirich TL, Meyer TW, Hostetter TH, Plummer NS, Hwang S, Melamed ML, Banerjee T, Coresh J, Powe NR.

Kidney Int. 2017 Dec;92(6):1484-1492. doi: 10.1016/j.kint.2017.05.012. Epub 2017 Jul 21.


Free and total p-cresol sulfate levels and infectious hospitalizations in hemodialysis patients in CHOICE and HEMO.

Banerjee T, Meyer TW, Shafi T, Hostetter TH, Melamed M, Zhu Y, Powe NR.

Medicine (Baltimore). 2017 Feb;96(6):e5799. doi: 10.1097/MD.0000000000005799.


Serum Asymmetric and Symmetric Dimethylarginine and Morbidity and Mortality in Hemodialysis Patients.

Shafi T, Hostetter TH, Meyer TW, Hwang S, Hai X, Melamed ML, Banerjee T, Coresh J, Powe NR.

Am J Kidney Dis. 2017 Jul;70(1):48-58. doi: 10.1053/j.ajkd.2016.10.033. Epub 2017 Jan 12.


Kt/Vurea and Nonurea Small Solute Levels in the Hemodialysis Study.

Meyer TW, Sirich TL, Fong KD, Plummer NS, Shafi T, Hwang S, Banerjee T, Zhu Y, Powe NR, Hai X, Hostetter TH.

J Am Soc Nephrol. 2016 Nov;27(11):3469-3478. Epub 2016 Mar 29.


Effect of oral sodium bicarbonate on fibroblast growth factor-23 in patients with chronic kidney disease: a pilot study.

Chen W, Melamed ML, Hostetter TH, Bauer C, Raff AC, Almudevar AL, Lalonde A, Messing S, Abramowitz MK.

BMC Nephrol. 2016 Aug 5;17(1):114. doi: 10.1186/s12882-016-0331-6.


Trimethylamine N-Oxide and Cardiovascular Events in Hemodialysis Patients.

Shafi T, Powe NR, Meyer TW, Hwang S, Hai X, Melamed ML, Banerjee T, Coresh J, Hostetter TH.

J Am Soc Nephrol. 2017 Jan;28(1):321-331. doi: 10.1681/ASN.2016030374. Epub 2016 Jul 19.


Federal Funding for Kidney Disease Research: A Missed Opportunity.

Mendu ML, Erickson KF, Hostetter TH, Winkelmayer WC, Olan G, Meyer RN, Hakim R, Sedor JR.

Am J Public Health. 2016 Mar;106(3):406-7. doi: 10.2105/AJPH.2015.303009. No abstract available.


Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients.

Hai X, Landeras V, Dobre MA, DeOreo P, Meyer TW, Hostetter TH.

PLoS One. 2015 Dec 9;10(12):e0143731. doi: 10.1371/journal.pone.0143731. eCollection 2015.


Free Levels of Selected Organic Solutes and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Results from the Retained Organic Solutes and Clinical Outcomes (ROSCO) Investigators.

Shafi T, Meyer TW, Hostetter TH, Melamed ML, Parekh RS, Hwang S, Banerjee T, Coresh J, Powe NR.

PLoS One. 2015 May 4;10(5):e0126048. doi: 10.1371/journal.pone.0126048. eCollection 2015.


Integrated renal care: are nephrologists ready for change in renal care delivery models?

Jones ER, Hostetter TH.

Clin J Am Soc Nephrol. 2015 Feb 6;10(2):335-9. doi: 10.2215/CJN.04440514. Epub 2014 Nov 17.


Current status of bicarbonate in CKD.

Dobre M, Rahman M, Hostetter TH.

J Am Soc Nephrol. 2015 Mar;26(3):515-23. doi: 10.1681/ASN.2014020205. Epub 2014 Aug 22. Review.


Effect of increasing dietary fiber on plasma levels of colon-derived solutes in hemodialysis patients.

Sirich TL, Plummer NS, Gardner CD, Hostetter TH, Meyer TW.

Clin J Am Soc Nephrol. 2014 Sep 5;9(9):1603-10. doi: 10.2215/CJN.00490114. Epub 2014 Aug 21.


Approaches to uremia.

Meyer TW, Hostetter TH.

J Am Soc Nephrol. 2014 Oct;25(10):2151-8. doi: 10.1681/ASN.2013121264. Epub 2014 May 8. Review.


Prominent accumulation in hemodialysis patients of solutes normally cleared by tubular secretion.

Sirich TL, Funk BA, Plummer NS, Hostetter TH, Meyer TW.

J Am Soc Nephrol. 2014 Mar;25(3):615-22. doi: 10.1681/ASN.2013060597. Epub 2013 Nov 14.


The authors reply.

Abramowitz MK, Hostetter TH, Melamed ML.

Kidney Int. 2013 Aug;84(2):414-5. doi: 10.1038/ki.2013.183. No abstract available.


Retained organic solutes, patient characteristics and all-cause and cardiovascular mortality in hemodialysis: results from the retained organic solutes and clinical outcomes (ROSCO) investigators.

Melamed ML, Plantinga L, Shafi T, Parekh R, Meyer TW, Hostetter TH, Coresh J, Powe NR.

BMC Nephrol. 2013 Jun 27;14:134. doi: 10.1186/1471-2369-14-134.


A zebrafish model for uremic toxicity: role of the complement pathway.

Berman N, Lectura M, Thurman J, Reinecke J, Raff AC, Melamed ML, Reinecke J, Quan Z, Evans T, Meyer TW, Hostetter TH.

Blood Purif. 2013;35(4):265-269. doi: 10.1159/000348456. Epub 2013 May 8.


Numerous protein-bound solutes are cleared by the kidney with high efficiency.

Sirich TL, Aronov PA, Plummer NS, Hostetter TH, Meyer TW.

Kidney Int. 2013 Sep;84(3):585-90. doi: 10.1038/ki.2013.154. Epub 2013 May 1.


Effects of oral sodium bicarbonate in patients with CKD.

Abramowitz MK, Melamed ML, Bauer C, Raff AC, Hostetter TH.

Clin J Am Soc Nephrol. 2013 May;8(5):714-20. doi: 10.2215/CJN.08340812. Epub 2013 Feb 7.


Considering an integrated nephrology care delivery model: six principles for quality.

Hamm LL, Hostetter TH, Shaffer RN; ASN Accountable Care Organization Task Force.

Clin J Am Soc Nephrol. 2013 Apr;8(4):682-6. doi: 10.2215/CJN.04460512. Epub 2012 Nov 26.


Searching for uremic toxins.

Dobre M, Meyer TW, Hostetter TH.

Clin J Am Soc Nephrol. 2013 Feb;8(2):322-7. doi: 10.2215/CJN.04260412. Epub 2012 Sep 27. Review.


The serum anion gap is altered in early kidney disease and associates with mortality.

Abramowitz MK, Hostetter TH, Melamed ML.

Kidney Int. 2012 Sep;82(6):701-9. doi: 10.1038/ki.2012.196. Epub 2012 May 23.


The production of p-cresol sulfate and indoxyl sulfate in vegetarians versus omnivores.

Patel KP, Luo FJ, Plummer NS, Hostetter TH, Meyer TW.

Clin J Am Soc Nephrol. 2012 Jun;7(6):982-8. doi: 10.2215/CJN.12491211. Epub 2012 Apr 5.


Family history of exceptional longevity is associated with lower serum uric acid levels in Ashkenazi Jews.

Lai JY, Atzmon G, Melamed ML, Hostetter TH, Crandall JP, Barzilai N, Bitzer M.

J Am Geriatr Soc. 2012 Apr;60(4):745-50. doi: 10.1111/j.1532-5415.2012.03902.x. Epub 2012 Mar 16.


Uremic solutes from colon microbes.

Meyer TW, Hostetter TH.

Kidney Int. 2012 May;81(10):949-954. doi: 10.1038/ki.2011.504. Epub 2012 Feb 8. Review.


Lower serum bicarbonate and a higher anion gap are associated with lower cardiorespiratory fitness in young adults.

Abramowitz MK, Hostetter TH, Melamed ML.

Kidney Int. 2012 May;81(10):1033-1042. doi: 10.1038/ki.2011.479. Epub 2012 Feb 1.


Selectively increasing the clearance of protein-bound uremic solutes.

Sirich TL, Luo FJ, Plummer NS, Hostetter TH, Meyer TW.

Nephrol Dial Transplant. 2012 Apr;27(4):1574-9. doi: 10.1093/ndt/gfr691. Epub 2012 Jan 9.


Family history and kidney disease.

Drawz PE, Sedor JR, Hostetter TH.

Am J Kidney Dis. 2012 Jan;59(1):9-10. doi: 10.1053/j.ajkd.2011.11.012. No abstract available.


Treatment of chronic kidney disease.

Turner JM, Bauer C, Abramowitz MK, Melamed ML, Hostetter TH.

Kidney Int. 2012 Feb;81(4):351-62. doi: 10.1038/ki.2011.380. Epub 2011 Dec 14. Review.


Dialysis cannot be dosed.

Meyer TW, Sirich TL, Hostetter TH.

Semin Dial. 2011 Sep-Oct;24(5):471-9. doi: 10.1111/j.1525-139X.2011.00979.x. Epub 2011 Sep 19.


Colonic contribution to uremic solutes.

Aronov PA, Luo FJ, Plummer NS, Quan Z, Holmes S, Hostetter TH, Meyer TW.

J Am Soc Nephrol. 2011 Sep;22(9):1769-76. doi: 10.1681/ASN.2010121220. Epub 2011 Jul 22.


World Kidney Day 2011.

Hostetter TH, Kochis DJ, Shaffer RN, Chertow G, Harmon WE, Klotman PE, Powe NR, Sedor JR, Smedberg PC, Watnick S, Winkelmayer WC; ASN Public Policy Board.

J Am Soc Nephrol. 2011 Mar;22(3):397-8. doi: 10.1681/ASN.2011020115. Epub 2011 Feb 25. No abstract available.


Association of serum bicarbonate levels with gait speed and quadriceps strength in older adults.

Abramowitz MK, Hostetter TH, Melamed ML.

Am J Kidney Dis. 2011 Jul;58(1):29-38. doi: 10.1053/j.ajkd.2010.12.021. Epub 2011 Feb 26.


Contribution of residual function to removal of protein-bound solutes in hemodialysis.

Marquez IO, Tambra S, Luo FY, Li Y, Plummer NS, Hostetter TH, Meyer TW.

Clin J Am Soc Nephrol. 2011 Feb;6(2):290-6. doi: 10.2215/CJN.06100710. Epub 2010 Oct 28.


Ionizing radiation exposure: another underrecognized risk factor for poor health outcomes in dialysis patients.

Melamed ML, Hostetter TH.

Kidney Int. 2010 Oct;78(8):724-5. doi: 10.1038/ki.2010.279.


ASN End-Stage Renal Disease Task Force: perspective on prospective payments for renal dialysis facilities.

Sedor JR, Watnick S, Patel UD, Cheung A, Harmon W, Himmelfarb J, Hostetter TH, Inrig JK, Mehrotra R, Robinson E, Smedberg PC, Shaffer RN; American Society of Nephrology ESRD Task Force.

J Am Soc Nephrol. 2010 Aug;21(8):1235-7. doi: 10.1681/ASN.2010060656. Epub 2010 Jul 22. No abstract available.


Clinical impact of reporting estimated glomerular filtration rates.

Hostetter TH, Levey AS, Stevens LA.

Clin Chem. 2010 Sep;56(9):1381-3. doi: 10.1373/clinchem.2010.147827. Epub 2010 Jul 13. No abstract available.


Anemia therapy in ESRD: time to move on.

Folkert VW, Meyer TW, Hostetter TH.

Clin J Am Soc Nephrol. 2010 Jul;5(7):1163-4. doi: 10.2215/CJN.03680410. Epub 2010 Jun 10. No abstract available.


Serum alkaline phosphatase and phosphate and risk of mortality and hospitalization.

Abramowitz M, Muntner P, Coco M, Southern W, Lotwin I, Hostetter TH, Melamed ML.

Clin J Am Soc Nephrol. 2010 Jun;5(6):1064-71. doi: 10.2215/CJN.08621209. Epub 2010 Apr 8.


Is angiotensin system blockade indicated in the elderly?

Bauer C, Abramowitz M, Hostetter TH.

Nat Rev Nephrol. 2010 Jan;6(1):11-2. doi: 10.1038/nrneph.2009.206. No abstract available.


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