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Items: 1 to 50 of 957

1.

Multicenter, Open-Label Study of Long-Term Topiroxostat (FYX-051) Administration in Japanese Hyperuricemic Patients with or Without Gout.

Hosoya T, Ishikawa T, Ogawa Y, Sakamoto R, Ohashi T.

Clin Drug Investig. 2018 Sep 15. doi: 10.1007/s40261-018-0699-0. [Epub ahead of print]

PMID:
30219951
2.

A pediatric case of Li-Fraumeni syndrome complicated with supratentorial anaplastic ependymoma.

Hosoya T, Kambe A, Nishimura Y, Sakamoto M, Maegaki Y, Kurosaki M.

World Neurosurg. 2018 Sep 6. pii: S1878-8750(18)31989-2. doi: 10.1016/j.wneu.2018.08.203. [Epub ahead of print]

PMID:
30196175
3.

Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial.

Kimura K, Hosoya T, Uchida S, Inaba M, Makino H, Maruyama S, Ito S, Yamamoto T, Tomino Y, Ohno I, Shibagaki Y, Iimuro S, Imai N, Kuwabara M, Hayakawa H, Ohtsu H, Ohashi Y; FEATHER Study Investigators.

Am J Kidney Dis. 2018 Aug 31. pii: S0272-6386(18)30834-5. doi: 10.1053/j.ajkd.2018.06.028. [Epub ahead of print]

PMID:
30177485
4.

A Remarkable Uptake of FDG in Huge Mediastinal Hashimoto' s Goiter.

Oka K, Hosoya T, Taira N, Otsuka F.

Intern Med. 2018 Aug 24. doi: 10.2169/internalmedicine.0898-18. [Epub ahead of print] No abstract available.

5.

A check list of non-lichenised fungi occurring on Fagus crenata, a tree endemic to Japan.

Hosoya T, Hosaka K, Nam KO.

Mycology. 2017 Aug 9;9(1):29-34. doi: 10.1080/21501203.2017.1363092. eCollection 2018.

6.

Sydowianumols A, B, and C, Three New Compounds from Discomycete Poculum pseudosydowianum.

Kawashima D, Hosoya T, Tomoda H, Kita M, Shigemori H.

Chem Pharm Bull (Tokyo). 2018;66(8):826-829. doi: 10.1248/cpb.c18-00264.

7.

Effect of the interaction of metformin and bone morphogenetic proteins on ovarian steroidogenesis by human granulosa cells.

Iwata N, Hasegawa T, Fujita S, Nagao S, Nakano Y, Nada T, Nishiyama Y, Hosoya T, Otsuka F.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1422-1427. doi: 10.1016/j.bbrc.2018.07.058. Epub 2018 Jul 13.

PMID:
30017187
8.

Syntheses and Structures of d10 Coinage Metal Complexes of Electron-Accepting Phosphine Ligands Featuring a 3,3,4,4,5,5-Hexafluorocyclopentene Framework.

Agou T, Wada N, Fujisawa K, Hosoya T, Mizuhata Y, Tokitoh N, Fukumoto H, Kubota T.

Inorg Chem. 2018 Aug 6;57(15):9105-9114. doi: 10.1021/acs.inorgchem.8b01111. Epub 2018 Jul 9.

PMID:
29984577
9.

Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist.

Hosoya T, Sato-Kaneko F, Ahmadi A, Yao S, Lao F, Kitaura K, Matsutani T, Carson DA, Hayashi T.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6836-E6844. doi: 10.1073/pnas.1803281115. Epub 2018 Jul 2.

PMID:
29967183
10.

Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation.

Meguro T, Yoshida S, Igawa K, Tomooka K, Hosoya T.

Org Lett. 2018 Jul 6;20(13):4126-4130. doi: 10.1021/acs.orglett.8b01692. Epub 2018 Jun 14.

PMID:
29901399
11.

The enigmatic Mixia osmundae revisited: a systematic review including new distributional data and recent advances in its phylogeny and phylogenomics.

Sugiyama J, Nishida H, Hosoya T, Kakishima M.

Mycologia. 2018 Jan-Feb;110(1):179-191. doi: 10.1080/00275514.2018.1429756.

PMID:
29864002
12.

Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin.

Inouye S, Tomabechi Y, Hosoya T, Sekine SI, Shirouzu M.

J Biochem. 2018 Sep 1;164(3):247-255. doi: 10.1093/jb/mvy049.

PMID:
29796619
13.

C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape.

Dayalan Naidu S, Muramatsu A, Saito R, Asami S, Honda T, Hosoya T, Itoh K, Yamamoto M, Suzuki T, Dinkova-Kostova AT.

Sci Rep. 2018 May 23;8(1):8037. doi: 10.1038/s41598-018-26269-9.

14.

Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells.

Meguro T, Terashima N, Ito H, Koike Y, Kii I, Yoshida S, Hosoya T.

Chem Commun (Camb). 2018 Jul 12;54(57):7904-7907. doi: 10.1039/c8cc00179k.

PMID:
29785430
15.

Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants.

Shukla NM, Arimoto KI, Yao S, Fan JB, Zhang Y, Sato-Kaneko F, Lao FS, Hosoya T, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T, Zhang DE, Corr M.

SLAS Discov. 2018 May 1:2472555218774308. doi: 10.1177/2472555218774308. [Epub ahead of print]

PMID:
29751735
16.

Binding of Catechins to Staphylococcal Enterotoxin A.

Shimamura Y, Utsumi M, Hirai C, Nakano S, Ito S, Tsuji A, Ishii T, Hosoya T, Kan T, Ohashi N, Masuda S.

Molecules. 2018 May 9;23(5). pii: E1125. doi: 10.3390/molecules23051125.

17.

CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia.

Ajiro M, Sakai H, Onogi H, Yamamoto M, Sumi E, Sawada T, Nomura T, Kabashima K, Hosoya T, Hagiwara M.

Clin Cancer Res. 2018 Sep 15;24(18):4518-4528. doi: 10.1158/1078-0432.CCR-17-3119. Epub 2018 Apr 30.

PMID:
29712686
18.

The ash dieback invasion of Europe was founded by two genetically divergent individuals.

McMullan M, Rafiqi M, Kaithakottil G, Clavijo BJ, Bilham L, Orton E, Percival-Alwyn L, Ward BJ, Edwards A, Saunders DGO, Garcia Accinelli G, Wright J, Verweij W, Koutsovoulos G, Yoshida K, Hosoya T, Williamson L, Jennings P, Ioos R, Husson C, Hietala AM, Vivian-Smith A, Solheim H, MaClean D, Fosker C, Hall N, Brown JKM, Swarbreck D, Blaxter M, Downie JA, Clark MD.

Nat Ecol Evol. 2018 Jun;2(6):1000-1008. doi: 10.1038/s41559-018-0548-9. Epub 2018 Apr 23.

PMID:
29686237
19.

Quantification of receptor activation by oxytocin and vasopressin in endocytosis-coupled bioluminescence reduction assay using nanoKAZ.

Kii I, Hirahara-Owada S, Yamaguchi M, Niwa T, Koike Y, Sonamoto R, Ito H, Takahashi K, Yokoyama C, Hayashi T, Hosoya T, Watanabe Y.

Anal Biochem. 2018 May 15;549:174-183. doi: 10.1016/j.ab.2018.04.001. Epub 2018 Apr 5.

PMID:
29627593
20.

Global dynamics of stage-specific transcription factor binding during thymocyte development.

Hosoya T, D'Oliveira Albanus R, Hensley J, Myers G, Kyono Y, Kitzman J, Parker SCJ, Engel JD.

Sci Rep. 2018 Apr 4;8(1):5605. doi: 10.1038/s41598-018-23774-9.

21.

Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions.

Yoshida S, Kanno K, Kii I, Misawa Y, Hagiwara M, Hosoya T.

Chem Commun (Camb). 2018 Apr 10;54(30):3705-3708. doi: 10.1039/c8cc01195h.

PMID:
29527608
22.

5-Hydroxyferulic acid methyl ester isolated from wasabi leaves inhibits 3T3-L1 adipocyte differentiation.

Misawa N, Hosoya T, Yoshida S, Sugimoto O, Yamada-Kato T, Kumazawa S.

Phytother Res. 2018 Jul;32(7):1304-1310. doi: 10.1002/ptr.6060. Epub 2018 Feb 26.

PMID:
29480572
23.

[Competence of public health nursing related to home visits by novice public health nurses in Yamagata].

Matsuda M, Morikagi Y, Hosoya T, Kobayashi A.

Nihon Koshu Eisei Zasshi. 2018;65(1):10-19. doi: 10.11236/jph.65.1_10. Japanese. No abstract available.

24.

Lactobacillus helveticus SBT2171 Attenuates Experimental Autoimmune Encephalomyelitis in Mice.

Yamashita M, Ukibe K, Matsubara Y, Hosoya T, Sakai F, Kon S, Arima Y, Murakami M, Nakagawa H, Miyazaki T.

Front Microbiol. 2018 Jan 22;8:2596. doi: 10.3389/fmicb.2017.02596. eCollection 2017.

25.

Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study).

Wada T, Hosoya T, Honda D, Sakamoto R, Narita K, Sasaki T, Okui D, Kimura K.

Clin Exp Nephrol. 2018 Aug;22(4):860-870. doi: 10.1007/s10157-018-1530-1. Epub 2018 Jan 25.

PMID:
29372470
26.

Simplified estimation of binding parameters based on image-derived reference tissue models for dopamine transporter bindings in non-human primates using [18F]FE-PE2I and PET.

Odano I, Varrone A, Hosoya T, Sakaguchi K, Gulyás B, Padmanabhan P, Ghosh KK, Yang CT, Guenther I, Wang Z, Serrano R, Chimon NG, Halldin C.

Am J Nucl Med Mol Imaging. 2017 Dec 20;7(6):246-254. eCollection 2017.

27.

Multiple common and rare variants of ABCG2 cause gout.

Higashino T, Takada T, Nakaoka H, Toyoda Y, Stiburkova B, Miyata H, Ikebuchi Y, Nakashima H, Shimizu S, Kawaguchi M, Sakiyama M, Nakayama A, Akashi A, Tanahashi Y, Kawamura Y, Nakamura T, Wakai K, Okada R, Yamamoto K, Hosomichi K, Hosoya T, Ichida K, Ooyama H, Suzuki H, Inoue I, Merriman TR, Shinomiya N, Matsuo H.

RMD Open. 2017 Aug 29;3(2):e000464. doi: 10.1136/rmdopen-2017-000464. eCollection 2017.

28.

Gender interaction of uric acid in the development of hypertension.

Nishio S, Maruyama Y, Sugano N, Hosoya T, Yokoo T, Kuriyama S.

Clin Exp Hypertens. 2018;40(5):446-451. doi: 10.1080/10641963.2017.1392556. Epub 2017 Nov 28.

PMID:
29182449
29.

Nymphaeol-C, a prenylflavonoid from Macaranga tanarius, suppresses the expression of fibroblast growth factor 18.

Yoshimura K, Hosoya T, Fujinami M, Ohta T, Kumazawa S.

Phytomedicine. 2017 Dec 1;36:238-242. doi: 10.1016/j.phymed.2017.10.009. Epub 2017 Oct 12.

PMID:
29157820
30.

Phylogenetic relationships of eight new Dacrymycetes collected from New Zealand.

Shirouzu T, Hosaka K, Nam KO, Weir BS, Johnston PR, Hosoya T.

Persoonia. 2017 Jun;38:156-169. doi: 10.3767/003158517X695280. Epub 2017 Mar 8.

31.

Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects.

Kusuhara H, Takashima T, Fujii H, Takashima T, Tanaka M, Ishii A, Tazawa S, Takahashi K, Takahashi K, Tokai H, Yano T, Kataoka M, Inano A, Yoshida S, Hosoya T, Sugiyama Y, Yamashita S, Hojo T, Watanabe Y.

Drug Metab Pharmacokinet. 2017 Dec;32(6):293-300. doi: 10.1016/j.dmpk.2017.09.003. Epub 2017 Sep 21.

PMID:
29137842
32.

Incretins modulate progesterone biosynthesis by regulating bone morphogenetic protein activity in rat granulosa cells.

Nishiyama Y, Hasegawa T, Fujita S, Iwata N, Nagao S, Hosoya T, Inagaki K, Wada J, Otsuka F.

J Steroid Biochem Mol Biol. 2018 Apr;178:82-88. doi: 10.1016/j.jsbmb.2017.11.004. Epub 2017 Nov 9.

PMID:
29129645
33.

Evaluation of the alternative classification criteria of systemic lupus erythematosus established by Systemic Lupus International Collaborating Clinics (SLICC).

Oku K, Atsumi T, Akiyama Y, Amano H, Azuma N, Bohgaki T, Asanuma YF, Horita T, Hosoya T, Ichinose K, Kato M, Katsumata Y, Kawaguchi Y, Kawakami A, Koga T, Kohsaka H, Kondo Y, Kubo K, Kuwana M, Mimori A, Mimori T, Mimura T, Murakami K, Nakano K, Nakayamada S, Ogishima H, Ohmura K, Saito K, Sano H, Shibuya M, Takahashi Y, Takasaki Y, Takeuchi T, Tamura N, Tanaka Y, Tsuboi H, Tsunoda S, Yukawa N, Yamakawa N, Yamamoto K, Sumida T.

Mod Rheumatol. 2018 Jul;28(4):642-648. doi: 10.1080/14397595.2017.1385154. Epub 2017 Nov 9.

PMID:
29120258
34.

Lattice system of functionally distinct cell types in the neocortex.

Maruoka H, Nakagawa N, Tsuruno S, Sakai S, Yoneda T, Hosoya T.

Science. 2017 Nov 3;358(6363):610-615. doi: 10.1126/science.aam6125.

PMID:
29097542
35.

Synthesis of Diverse o-Arylthio-Substituted Diaryl Ethers by Direct Oxythiolation of Arynes with Diaryl Sulfoxides Involving Migratory O-Arylation.

Matsuzawa T, Uchida K, Yoshida S, Hosoya T.

Org Lett. 2017 Oct 20;19(20):5521-5524. doi: 10.1021/acs.orglett.7b02599. Epub 2017 Oct 6.

PMID:
28984457
36.

Superficial Siderosis Associated with a Spinal Dural Defect.

Hiraka T, Kanoto M, Toyoguchi Y, Igari R, Kato T, Hosoya T.

Magn Reson Med Sci. 2018 Jul 10;17(3):189-190. doi: 10.2463/mrms.ci.2017-0043. Epub 2017 Oct 3. No abstract available.

37.

Degradation of the Cellulosic Key Chromophore 5,8-Dihydroxy-[1,4]-naphthoquinone by Hydrogen Peroxide under Alkaline Conditions.

Zwirchmayr NS, Hosoya T, Henniges U, Gille L, Bacher M, Furtm├╝ller P, Rosenau T.

J Org Chem. 2017 Nov 3;82(21):11558-11565. doi: 10.1021/acs.joc.7b01827.

PMID:
28968096
38.

A study on an unusual SN2 mechanism in the methylation of benzyne through nickel-complexation.

Hatakeyama M, Sakamoto Y, Ogata K, Sumida Y, Sumida T, Hosoya T, Nakamura S.

Phys Chem Chem Phys. 2017 Oct 11;19(39):26926-26933. doi: 10.1039/c7cp04739h.

PMID:
28956039
39.

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

Sato-Kaneko F, Yao S, Ahmadi A, Zhang SS, Hosoya T, Kaneda MM, Varner JA, Pu M, Messer KS, Guiducci C, Coffman RL, Kitaura K, Matsutani T, Suzuki R, Carson DA, Hayashi T, Cohen EE.

JCI Insight. 2017 Sep 21;2(18). pii: 93397. doi: 10.1172/jci.insight.93397. [Epub ahead of print]

40.

Prediction of Cognitive Decline from White Matter Hyperintensity and Single-Photon Emission Computed Tomography in Alzheimer's Disease.

Tabei KI, Kida H, Hosoya T, Satoh M, Tomimoto H.

Front Neurol. 2017 Sep 4;8:408. doi: 10.3389/fneur.2017.00408. eCollection 2017.

41.

Construction of Condensed Polycyclic Aromatic Frameworks through Intramolecular Cycloaddition Reactions Involving Arynes Bearing an Internal Alkyne Moiety.

Yoshida S, Shimizu K, Uchida K, Hazama Y, Igawa K, Tomooka K, Hosoya T.

Chemistry. 2017 Nov 2;23(61):15332-15335. doi: 10.1002/chem.201704345. Epub 2017 Oct 10.

PMID:
28921682
42.

Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates.

Kanemoto K, Sugimura Y, Shimizu S, Yoshida S, Hosoya T.

Chem Commun (Camb). 2017 Sep 26;53(77):10640-10643. doi: 10.1039/c7cc05868c.

PMID:
28920976
43.

Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice.

Nakano-Kobayashi A, Awaya T, Kii I, Sumida Y, Okuno Y, Yoshida S, Sumida T, Inoue H, Hosoya T, Hagiwara M.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10268-10273. doi: 10.1073/pnas.1704143114. Epub 2017 Sep 5.

44.

Copper-Catalyzed Regioselective Monodefluoroborylation of Polyfluoroalkenes en Route to Diverse Fluoroalkenes.

Sakaguchi H, Uetake Y, Ohashi M, Niwa T, Ogoshi S, Hosoya T.

J Am Chem Soc. 2017 Sep 13;139(36):12855-12862. doi: 10.1021/jacs.7b08343. Epub 2017 Sep 5.

PMID:
28849929
45.

Paleoseismic study of the Kamishiro Fault on the northern segment of the Itoigawa-Shizuoka Tectonic Line, Japan.

Lin A, Sano M, Wang M, Yan B, Bian D, Fueta R, Hosoya T.

J Seismol. 2017;21(4):683-703. doi: 10.1007/s10950-016-9629-x. Epub 2016 Nov 21.

46.

Synthesis of Unsymmetrical Tertiary Phosphine Oxides via Sequential Substitution Reaction of Phosphonic Acid Dithioesters with Grignard Reagents.

Nishiyama Y, Hazama Y, Yoshida S, Hosoya T.

Org Lett. 2017 Jul 21;19(14):3899-3902. doi: 10.1021/acs.orglett.7b01796. Epub 2017 Jul 11.

PMID:
28696122
47.

A regulatory role of androgen in ovarian steroidogenesis by rat granulosa cells.

Hasegawa T, Kamada Y, Hosoya T, Fujita S, Nishiyama Y, Iwata N, Hiramatsu Y, Otsuka F.

J Steroid Biochem Mol Biol. 2017 Sep;172:160-165. doi: 10.1016/j.jsbmb.2017.07.002. Epub 2017 Jul 4.

PMID:
28684382
48.

Preventive Effect of Lactobacillus helveticus SBT2171 on Collagen-Induced Arthritis in Mice.

Yamashita M, Matsumoto K, Endo T, Ukibe K, Hosoya T, Matsubara Y, Nakagawa H, Sakai F, Miyazaki T.

Front Microbiol. 2017 Jun 21;8:1159. doi: 10.3389/fmicb.2017.01159. eCollection 2017.

49.

Three-Dimensional Localization of an Individual Fluorescent Molecule with Angstrom Precision.

Furubayashi T, Motohashi K, Wakao K, Matsuda T, Kii I, Hosoya T, Hayashi N, Sadaie M, Ishikawa F, Matsushita M, Fujiyoshi S.

J Am Chem Soc. 2017 Jul 5;139(26):8990-8994. doi: 10.1021/jacs.7b03899. Epub 2017 Jun 23.

PMID:
28644014
50.

Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy.

Sako Y, Ninomiya K, Okuno Y, Toyomoto M, Nishida A, Koike Y, Ohe K, Kii I, Yoshida S, Hashimoto N, Hosoya T, Matsuo M, Hagiwara M.

Sci Rep. 2017 May 30;7:46126. doi: 10.1038/srep46126.

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