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Items: 1 to 50 of 977

1.

The basic repeating modules of the cerebral cortical circuit.

Hosoya T.

Proc Jpn Acad Ser B Phys Biol Sci. 2019;95(7):303-311. doi: 10.2183/pjab.95.022.

2.

Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.

Kawamura Y, Nakaoka H, Nakayama A, Okada Y, Yamamoto K, Higashino T, Sakiyama M, Shimizu T, Ooyama H, Ooyama K, Nagase M, Hidaka Y, Shirahama Y, Hosomichi K, Nishida Y, Shimoshikiryo I, Hishida A, Katsuura-Kamano S, Shimizu S, Kawaguchi M, Uemura H, Ibusuki R, Hara M, Naito M, Takao M, Nakajima M, Iwasawa S, Nakashima H, Ohnaka K, Nakamura T, Stiburkova B, Merriman TR, Nakatochi M, Ichihara S, Yokota M, Takada T, Saitoh T, Kamatani Y, Takahashi A, Arisawa K, Takezaki T, Tanaka K, Wakai K, Kubo M, Hosoya T, Ichida K, Inoue I, Shinomiya N, Matsuo H.

Ann Rheum Dis. 2019 Oct;78(10):1430-1437. doi: 10.1136/annrheumdis-2019-215521. Epub 2019 Jul 8.

3.

Synthesis and characterization of bent fluorine-containing donor-π-acceptor molecules as intense luminophores with large Stokes shifts.

Yamada S, Nishizawa A, Morita M, Hosokai T, Okabayashi Y, Agou T, Hosoya T, Kubota T, Konno T.

Org Biomol Chem. 2019 Jul 17;17(28):6911-6919. doi: 10.1039/c9ob01300h.

PMID:
31271184
4.

Synthesis of (2,2-Diborylvinyl)arenes by Rhodium-Catalyzed Desulfanylative gem-Diborylation of 2-Arylvinyl Sulfides.

Uetake Y, Isoda M, Niwa T, Hosoya T.

Org Lett. 2019 Jul 5;21(13):4933-4938. doi: 10.1021/acs.orglett.9b01253. Epub 2019 Jun 24.

PMID:
31247744
5.

3-Thioaryne Intermediates for the Synthesis of Diverse Thioarenes.

Nakamura Y, Miyata Y, Uchida K, Yoshida S, Hosoya T.

Org Lett. 2019 Jul 5;21(13):5252-5258. doi: 10.1021/acs.orglett.9b01862. Epub 2019 Jun 25.

PMID:
31247741
6.

Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates.

Kanemoto K, Yoshida S, Hosoya T.

Org Lett. 2019 May 3;21(9):3172-3177. doi: 10.1021/acs.orglett.9b00875. Epub 2019 Apr 19.

PMID:
31002255
7.

A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach.

Yoshida S, Kuribara T, Ito H, Meguro T, Nishiyama Y, Karaki F, Hatakeyama Y, Koike Y, Kii I, Hosoya T.

Chem Commun (Camb). 2019 Mar 19;55(24):3556-3559. doi: 10.1039/c9cc01113g.

PMID:
30843553
8.

Slow Dynamics in Microcolumnar Gap Junction Network of Developing Neocortical Pyramidal Neurons.

Nakagawa N, Hosoya T.

Neuroscience. 2019 May 15;406:554-562. doi: 10.1016/j.neuroscience.2019.02.013. Epub 2019 Feb 20.

PMID:
30794844
9.

[Totally Laparoscopic Stomach-Partitioning Gastrojejunostomy for Gastroduodenal Outlet Obstruction for Elderly Cancer Patients].

Yoshimura T, Yamamoto E, Koshiishi H, Goto H, Hoshino M, Sugimoto H, Matsunaga H, Kamiya A, Ogawa N, Hosoya T, Shigehara F.

Gan To Kagaku Ryoho. 2018 Dec;45(13):1919-1921. Japanese.

PMID:
30692397
10.

[The Basic Modules of the Neocortex].

Hosoya T, Nakagawa N, Yoneda T, Maruoka H.

Brain Nerve. 2018 Dec;70(12):1381-1388. doi: 10.11477/mf.1416201197. Japanese.

PMID:
30523218
11.

Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial.

J-DAVID Investigators, Shoji T, Inaba M, Fukagawa M, Ando R, Emoto M, Fujii H, Fujimori A, Fukui M, Hase H, Hashimoto T, Hirakata H, Honda H, Hosoya T, Ikari Y, Inaguma D, Inoue T, Isaka Y, Iseki K, Ishimura E, Itami N, Ito C, Kakuta T, Kawai T, Kawanishi H, Kobayashi S, Kumagai J, Maekawa K, Masakane I, Minakuchi J, Mitsuiki K, Mizuguchi T, Morimoto S, Murohara T, Nakatani T, Negi S, Nishi S, Nishikawa M, Ogawa T, Ohta K, Ohtake T, Okamura M, Okuno S, Shigematsu T, Sugimoto T, Suzuki M, Tahara H, Takemoto Y, Tanaka K, Tominaga Y, Tsubakihara Y, Tsujimoto Y, Tsuruya K, Ueda S, Watanabe Y, Yamagata K, Yamakawa T, Yano S, Yokoyama K, Yorioka N, Yoshiyama M, Nishizawa Y.

JAMA. 2018 Dec 11;320(22):2325-2334. doi: 10.1001/jama.2018.17749.

12.

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface.

Toyoda Y, Morimoto K, Suno R, Horita S, Yamashita K, Hirata K, Sekiguchi Y, Yasuda S, Shiroishi M, Shimizu T, Urushibata Y, Kajiwara Y, Inazumi T, Hotta Y, Asada H, Nakane T, Shiimura Y, Nakagita T, Tsuge K, Yoshida S, Kuribara T, Hosoya T, Sugimoto Y, Nomura N, Sato M, Hirokawa T, Kinoshita M, Murata T, Takayama K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T.

Nat Chem Biol. 2019 Jan;15(1):18-26. doi: 10.1038/s41589-018-0131-3. Epub 2018 Dec 3.

PMID:
30510193
13.

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

Yu L, Jearawiriyapaisarn N, Lee MP, Hosoya T, Wu Q, Myers G, Lim KC, Kurita R, Nakamura Y, Vojtek AB, Rual JF, Engel JD.

Genes Dev. 2018 Dec 1;32(23-24):1537-1549. doi: 10.1101/gad.318436.118. Epub 2018 Nov 21.

14.

Association between aromatase in human brains and personality traits.

Takahashi K, Hosoya T, Onoe K, Takashima T, Tanaka M, Ishii A, Nakatomi Y, Tazawa S, Takahashi K, Doi H, Wada Y, Watanabe Y.

Sci Rep. 2018 Nov 15;8(1):16841. doi: 10.1038/s41598-018-35065-4.

15.

Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy.

Sato-Kaneko F, Wang X, Yao S, Hosoya T, Lao FS, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Carson DA, Corr M, Hayashi T.

Biomed Res Int. 2018 Oct 10;2018:8091283. doi: 10.1155/2018/8091283. eCollection 2018.

16.

Status of the neutron time-of-flight single-crystal diffraction data-processing software STARGazer.

Yano N, Yamada T, Hosoya T, Ohhara T, Tanaka I, Niimura N, Kusaka K.

Acta Crystallogr D Struct Biol. 2018 Nov 1;74(Pt 11):1041-1052. doi: 10.1107/S2059798318012081. Epub 2018 Oct 29.

17.

High-Throughput Single-Cell Sequencing of both TCR-β Alleles.

Hosoya T, Li H, Ku CJ, Wu Q, Guan Y, Engel JD.

J Immunol. 2018 Dec 1;201(11):3465-3470. doi: 10.4049/jimmunol.1800774. Epub 2018 Oct 31.

PMID:
30381480
18.

Further enhancement of the clickability of doubly sterically-hindered aryl azides by para-amino substitution.

Yoshida S, Tanaka J, Nishiyama Y, Hazama Y, Matsushita T, Hosoya T.

Chem Commun (Camb). 2018 Nov 29;54(96):13499-13502. doi: 10.1039/c8cc05791e.

PMID:
30357141
19.

Palladium(ii)-mediated rapid 11C-cyanation of (hetero)arylborons.

Zhang Z, Niwa T, Watanabe Y, Hosoya T.

Org Biomol Chem. 2018 Nov 7;16(41):7711-7716. doi: 10.1039/c8ob02049c. Epub 2018 Oct 5.

PMID:
30288522
20.

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex.

Yoneda T, Sakai S, Maruoka H, Hosoya T.

J Vis Exp. 2018 Sep 5;(139). doi: 10.3791/58027.

PMID:
30247471
21.

Multicenter, Open-Label Study of Long-Term Topiroxostat (FYX-051) Administration in Japanese Hyperuricemic Patients with or Without Gout.

Hosoya T, Ishikawa T, Ogawa Y, Sakamoto R, Ohashi T.

Clin Drug Investig. 2018 Dec;38(12):1135-1143. doi: 10.1007/s40261-018-0699-0.

22.

Pediatric Case of Li-Fraumeni Syndrome Complicated with Supratentorial Anaplastic Ependymoma.

Hosoya T, Kambe A, Nishimura Y, Sakamoto M, Maegaki Y, Kurosaki M.

World Neurosurg. 2018 Dec;120:125-128. doi: 10.1016/j.wneu.2018.08.203. Epub 2018 Sep 6.

PMID:
30196175
23.

Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial.

Kimura K, Hosoya T, Uchida S, Inaba M, Makino H, Maruyama S, Ito S, Yamamoto T, Tomino Y, Ohno I, Shibagaki Y, Iimuro S, Imai N, Kuwabara M, Hayakawa H, Ohtsu H, Ohashi Y; FEATHER Study Investigators.

Am J Kidney Dis. 2018 Dec;72(6):798-810. doi: 10.1053/j.ajkd.2018.06.028. Epub 2018 Sep 1.

24.

A Remarkable Uptake of FDG in Huge Mediastinal Hashimoto's Goiter.

Oka K, Hosoya T, Taira N, Otsuka F.

Intern Med. 2019 Jan 15;58(2):313-314. doi: 10.2169/internalmedicine.0898-18. Epub 2018 Aug 24. No abstract available.

25.

A check list of non-lichenised fungi occurring on Fagus crenata, a tree endemic to Japan.

Hosoya T, Hosaka K, Nam KO.

Mycology. 2017 Aug 9;9(1):29-34. doi: 10.1080/21501203.2017.1363092. eCollection 2018.

26.

Sydowianumols A, B, and C, Three New Compounds from Discomycete Poculum pseudosydowianum.

Kawashima D, Hosoya T, Tomoda H, Kita M, Shigemori H.

Chem Pharm Bull (Tokyo). 2018;66(8):826-829. doi: 10.1248/cpb.c18-00264.

27.

Effect of the interaction of metformin and bone morphogenetic proteins on ovarian steroidogenesis by human granulosa cells.

Iwata N, Hasegawa T, Fujita S, Nagao S, Nakano Y, Nada T, Nishiyama Y, Hosoya T, Otsuka F.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1422-1427. doi: 10.1016/j.bbrc.2018.07.058. Epub 2018 Jul 13.

PMID:
30017187
28.

Syntheses and Structures of d10 Coinage Metal Complexes of Electron-Accepting Phosphine Ligands Featuring a 3,3,4,4,5,5-Hexafluorocyclopentene Framework.

Agou T, Wada N, Fujisawa K, Hosoya T, Mizuhata Y, Tokitoh N, Fukumoto H, Kubota T.

Inorg Chem. 2018 Aug 6;57(15):9105-9114. doi: 10.1021/acs.inorgchem.8b01111. Epub 2018 Jul 9.

PMID:
29984577
29.

Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist.

Hosoya T, Sato-Kaneko F, Ahmadi A, Yao S, Lao F, Kitaura K, Matsutani T, Carson DA, Hayashi T.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6836-E6844. doi: 10.1073/pnas.1803281115. Epub 2018 Jul 2.

30.

Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation.

Meguro T, Yoshida S, Igawa K, Tomooka K, Hosoya T.

Org Lett. 2018 Jul 6;20(13):4126-4130. doi: 10.1021/acs.orglett.8b01692. Epub 2018 Jun 14.

PMID:
29901399
31.

The enigmatic Mixia osmundae revisited: a systematic review including new distributional data and recent advances in its phylogeny and phylogenomics.

Sugiyama J, Nishida H, Hosoya T, Kakishima M.

Mycologia. 2018 Jan-Feb;110(1):179-191. doi: 10.1080/00275514.2018.1429756. Erratum in: Mycologia. 2018 Jul-Aug;110(4):795.

PMID:
29864002
32.

Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin.

Inouye S, Tomabechi Y, Hosoya T, Sekine SI, Shirouzu M.

J Biochem. 2018 Sep 1;164(3):247-255. doi: 10.1093/jb/mvy049.

PMID:
29796619
33.

C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape.

Dayalan Naidu S, Muramatsu A, Saito R, Asami S, Honda T, Hosoya T, Itoh K, Yamamoto M, Suzuki T, Dinkova-Kostova AT.

Sci Rep. 2018 May 23;8(1):8037. doi: 10.1038/s41598-018-26269-9.

34.

Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells.

Meguro T, Terashima N, Ito H, Koike Y, Kii I, Yoshida S, Hosoya T.

Chem Commun (Camb). 2018 Jul 12;54(57):7904-7907. doi: 10.1039/c8cc00179k.

PMID:
29785430
35.

Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants.

Shukla NM, Arimoto KI, Yao S, Fan JB, Zhang Y, Sato-Kaneko F, Lao FS, Hosoya T, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T, Zhang DE, Corr M.

SLAS Discov. 2018 Oct;23(9):960-973. doi: 10.1177/2472555218774308. Epub 2018 May 11.

36.

Binding of Catechins to Staphylococcal Enterotoxin A.

Shimamura Y, Utsumi M, Hirai C, Nakano S, Ito S, Tsuji A, Ishii T, Hosoya T, Kan T, Ohashi N, Masuda S.

Molecules. 2018 May 9;23(5). pii: E1125. doi: 10.3390/molecules23051125.

37.

CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia.

Ajiro M, Sakai H, Onogi H, Yamamoto M, Sumi E, Sawada T, Nomura T, Kabashima K, Hosoya T, Hagiwara M.

Clin Cancer Res. 2018 Sep 15;24(18):4518-4528. doi: 10.1158/1078-0432.CCR-17-3119. Epub 2018 Apr 30.

38.

The ash dieback invasion of Europe was founded by two genetically divergent individuals.

McMullan M, Rafiqi M, Kaithakottil G, Clavijo BJ, Bilham L, Orton E, Percival-Alwyn L, Ward BJ, Edwards A, Saunders DGO, Garcia Accinelli G, Wright J, Verweij W, Koutsovoulos G, Yoshida K, Hosoya T, Williamson L, Jennings P, Ioos R, Husson C, Hietala AM, Vivian-Smith A, Solheim H, MaClean D, Fosker C, Hall N, Brown JKM, Swarbreck D, Blaxter M, Downie JA, Clark MD.

Nat Ecol Evol. 2018 Jun;2(6):1000-1008. doi: 10.1038/s41559-018-0548-9. Epub 2018 Apr 23.

39.

Quantification of receptor activation by oxytocin and vasopressin in endocytosis-coupled bioluminescence reduction assay using nanoKAZ.

Kii I, Hirahara-Owada S, Yamaguchi M, Niwa T, Koike Y, Sonamoto R, Ito H, Takahashi K, Yokoyama C, Hayashi T, Hosoya T, Watanabe Y.

Anal Biochem. 2018 May 15;549:174-183. doi: 10.1016/j.ab.2018.04.001. Epub 2018 Apr 5.

PMID:
29627593
40.

Global dynamics of stage-specific transcription factor binding during thymocyte development.

Hosoya T, D'Oliveira Albanus R, Hensley J, Myers G, Kyono Y, Kitzman J, Parker SCJ, Engel JD.

Sci Rep. 2018 Apr 4;8(1):5605. doi: 10.1038/s41598-018-23774-9.

41.

Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions.

Yoshida S, Kanno K, Kii I, Misawa Y, Hagiwara M, Hosoya T.

Chem Commun (Camb). 2018 Apr 10;54(30):3705-3708. doi: 10.1039/c8cc01195h.

PMID:
29527608
42.

5-Hydroxyferulic acid methyl ester isolated from wasabi leaves inhibits 3T3-L1 adipocyte differentiation.

Misawa N, Hosoya T, Yoshida S, Sugimoto O, Yamada-Kato T, Kumazawa S.

Phytother Res. 2018 Jul;32(7):1304-1310. doi: 10.1002/ptr.6060. Epub 2018 Feb 26.

PMID:
29480572
43.

[Competence of public health nursing related to home visits by novice public health nurses in Yamagata].

Matsuda M, Morikagi Y, Hosoya T, Kobayashi A.

Nihon Koshu Eisei Zasshi. 2018;65(1):10-19. doi: 10.11236/jph.65.1_10. Japanese. No abstract available.

44.

Lactobacillus helveticus SBT2171 Attenuates Experimental Autoimmune Encephalomyelitis in Mice.

Yamashita M, Ukibe K, Matsubara Y, Hosoya T, Sakai F, Kon S, Arima Y, Murakami M, Nakagawa H, Miyazaki T.

Front Microbiol. 2018 Jan 22;8:2596. doi: 10.3389/fmicb.2017.02596. eCollection 2017.

45.

Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study).

Wada T, Hosoya T, Honda D, Sakamoto R, Narita K, Sasaki T, Okui D, Kimura K.

Clin Exp Nephrol. 2018 Aug;22(4):860-870. doi: 10.1007/s10157-018-1530-1. Epub 2018 Jan 25.

PMID:
29372470
46.

Simplified estimation of binding parameters based on image-derived reference tissue models for dopamine transporter bindings in non-human primates using [18F]FE-PE2I and PET.

Odano I, Varrone A, Hosoya T, Sakaguchi K, Gulyás B, Padmanabhan P, Ghosh KK, Yang CT, Guenther I, Wang Z, Serrano R, Chimon NG, Halldin C.

Am J Nucl Med Mol Imaging. 2017 Dec 20;7(6):246-254. eCollection 2017.

47.

Multiple common and rare variants of ABCG2 cause gout.

Higashino T, Takada T, Nakaoka H, Toyoda Y, Stiburkova B, Miyata H, Ikebuchi Y, Nakashima H, Shimizu S, Kawaguchi M, Sakiyama M, Nakayama A, Akashi A, Tanahashi Y, Kawamura Y, Nakamura T, Wakai K, Okada R, Yamamoto K, Hosomichi K, Hosoya T, Ichida K, Ooyama H, Suzuki H, Inoue I, Merriman TR, Shinomiya N, Matsuo H.

RMD Open. 2017 Aug 29;3(2):e000464. doi: 10.1136/rmdopen-2017-000464. eCollection 2017.

48.

Gender interaction of uric acid in the development of hypertension.

Nishio S, Maruyama Y, Sugano N, Hosoya T, Yokoo T, Kuriyama S.

Clin Exp Hypertens. 2018;40(5):446-451. doi: 10.1080/10641963.2017.1392556. Epub 2017 Nov 28.

PMID:
29182449
49.

Nymphaeol-C, a prenylflavonoid from Macaranga tanarius, suppresses the expression of fibroblast growth factor 18.

Yoshimura K, Hosoya T, Fujinami M, Ohta T, Kumazawa S.

Phytomedicine. 2017 Dec 1;36:238-242. doi: 10.1016/j.phymed.2017.10.009. Epub 2017 Oct 12.

PMID:
29157820
50.

Phylogenetic relationships of eight new Dacrymycetes collected from New Zealand.

Shirouzu T, Hosaka K, Nam KO, Weir BS, Johnston PR, Hosoya T.

Persoonia. 2017 Jun;38:156-169. doi: 10.3767/003158517X695280. Epub 2017 Mar 8.

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