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Items: 1 to 50 of 383

1.

Comparison of three mobilization protocols for peripheral blood stem cell apheresis with Spectra Optia continuous mononuclear cell protocol in healthy dogs.

Kim S, Hosoya K, Kobayashi A, Okumura M.

Vet Comp Oncol. 2018 Sep 17. doi: 10.1111/vco.12446. [Epub ahead of print]

PMID:
30221450
2.

Independent chondrogenic potential of canine bone marrow-derived mesenchymal stem cells in monolayer expansion cultures decreases in a passage-dependent pattern.

Bwalya EC, Wijekoon HS, Fang J, Kim S, Hosoya K, Okumura M.

J Vet Med Sci. 2018 Sep 11. doi: 10.1292/jvms.18-0202. [Epub ahead of print]

3.

Multiple Cellular Transport and Binding Processes of Unesterified Docosahexaenoic Acid in Outer Blood-Retinal Barrier Retinal Pigment Epithelial Cells.

Tachikawa M, Akanuma SI, Imai T, Okayasu S, Tomohiro T, Hatanaka Y, Hosoya KI.

Biol Pharm Bull. 2018;41(9):1384-1392. doi: 10.1248/bpb.b18-00185.

4.

Impact of Nicotine Transport across the Blood-Brain Barrier: Carrier-Mediated Transport of Nicotine and Interaction with Central Nervous System Drugs.

Tega Y, Yamazaki Y, Akanuma SI, Kubo Y, Hosoya KI.

Biol Pharm Bull. 2018;41(9):1330-1336. doi: 10.1248/bpb.b18-00134.

5.

Mandibular vascular hamartoma in a cat.

Takagi S, Kagawa Y, Hanazono K, Murakami S, Deguchi T, Izumi Y, Hosoya K, Kim S, Okumura M.

J Vet Med Sci. 2018 Sep 26;80(9):1456-1458. doi: 10.1292/jvms.18-0148. Epub 2018 Jul 13.

6.

Investigation of Receptor-Mediated Cyanocobalamin (Vitamin B12) Transport across the Inner Blood-Retinal Barrier Using Fluorescence-Labeled Cyanocobalamin.

Kinoshita Y, Nogami K, Jomura R, Akanuma SI, Abe H, Inouye M, Kubo Y, Hosoya KI.

Mol Pharm. 2018 Aug 6;15(8):3583-3594. doi: 10.1021/acs.molpharmaceut.8b00617. Epub 2018 Jul 17.

PMID:
29966424
7.

Response to neoadjuvant chemotherapy for breast cancer judged by PERCIST - multicenter study in Japan.

Kitajima K, Nakatani K, Yamaguchi K, Nakajo M, Tani A, Ishibashi M, Hosoya K, Morita T, Kinoshita T, Kaida H, Miyoshi Y.

Eur J Nucl Med Mol Imaging. 2018 May 12. doi: 10.1007/s00259-018-4008-1. [Epub ahead of print]

PMID:
29754160
8.

Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow.

Wijekoon HMS, Bwalya EC, Fang J, Kim S, Hosoya K, Okumura M.

BMC Vet Res. 2018 May 2;14(1):152. doi: 10.1186/s12917-018-1466-4.

9.

Recent advances in drug and nutrient transport across the blood-retinal barrier.

Kubo Y, Akanuma SI, Hosoya KI.

Expert Opin Drug Metab Toxicol. 2018 May;14(5):513-531. doi: 10.1080/17425255.2018.1472764. Epub 2018 May 10. Review.

PMID:
29719158
10.

Asymmetric Epoxidation of 1,4-Naphthoquinones Catalyzed by Guanidine-Urea Bifunctional Organocatalyst.

Kawaguchi M, Nakano K, Hosoya K, Orihara T, Yamanaka M, Odagi M, Nagasawa K.

Org Lett. 2018 May 18;20(10):2811-2815. doi: 10.1021/acs.orglett.8b00641. Epub 2018 May 2.

PMID:
29717876
11.

Role of l-Type Amino Acid Transporter 1 at the Inner Blood-Retinal Barrier in the Blood-to-Retina Transport of Gabapentin.

Akanuma SI, Yamakoshi A, Sugouchi T, Kubo Y, Hartz AMS, Bauer B, Hosoya KI.

Mol Pharm. 2018 Jun 4;15(6):2327-2337. doi: 10.1021/acs.molpharmaceut.8b00179. Epub 2018 May 2.

PMID:
29688723
12.

Blood-to-Retina Transport of Fluorescence-Labeled Verapamil at the Blood-Retinal Barrier.

Kubo Y, Nakazawa A, Akanuma SI, Hosoya KI.

Pharm Res. 2018 Mar 12;35(5):93. doi: 10.1007/s11095-018-2384-7.

PMID:
29532174
13.

Gene expression of A6-like subgroup of ATP-binding cassette transporters in mouse brain parenchyma and microvessels.

Tachikawa M, Toki H, Watanabe M, Tomi M, Hosoya KI, Terasaki T.

Anat Sci Int. 2018 Sep;93(4):456-463. doi: 10.1007/s12565-018-0435-0. Epub 2018 Mar 8.

PMID:
29520568
14.
15.

Expression and function of connexin 43 protein in mouse and human retinal pigment epithelial cells as hemichannels and gap junction proteins.

Akanuma SI, Higashi H, Maruyama S, Murakami K, Tachikawa M, Kubo Y, Hosoya KI.

Exp Eye Res. 2018 Mar;168:128-137. doi: 10.1016/j.exer.2018.01.016. Epub 2018 Jan 31.

PMID:
29366904
16.

Role of cationic drug-sensitive transport systems at the blood-cerebrospinal fluid barrier in para-tyramine elimination from rat brain.

Akanuma SI, Yamazaki Y, Kubo Y, Hosoya KI.

Fluids Barriers CNS. 2018 Jan 8;15(1):1. doi: 10.1186/s12987-017-0087-9.

17.

Evolution of the connection patterns of the cephalic lateral line canal system and its use to diagnose opsariichthyin cyprinid fishes (Teleostei, Cyprinidae).

Ito T, Fukuda T, Morimune T, Hosoya K.

Zookeys. 2017 Dec 4;(718):115-131. doi: 10.3897/zookeys.718.13574. eCollection 2017.

18.

Developmental changes of l-arginine transport at the blood-brain barrier in rats.

Tachikawa M, Hirose S, Akanuma SI, Matsuyama R, Hosoya KI.

Microvasc Res. 2018 May;117:16-21. doi: 10.1016/j.mvr.2017.12.003. Epub 2017 Dec 14.

PMID:
29247719
19.

Cell-Type-Specific Spatiotemporal Expression of Creatine Biosynthetic Enzyme S-adenosylmethionine:guanidinoacetate N-methyltransferase in Developing Mouse Brain.

Tachikawa M, Watanabe M, Fukaya M, Sakai K, Terasaki T, Hosoya KI.

Neurochem Res. 2018 Feb;43(2):500-510. doi: 10.1007/s11064-017-2446-y. Epub 2017 Dec 5.

PMID:
29209878
20.

Astrocytic γ-aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain.

Tachikawa M, Yashiki A, Akanuma SI, Matsukawa H, Ide S, Minami M, Hosoya KI.

Neurochem Int. 2018 Feb;113:1-7. doi: 10.1016/j.neuint.2017.11.013. Epub 2017 Nov 24.

PMID:
29175673
21.

Chronological differential effects of pro-inflammatory cytokines on RANKL-induced osteoclast differentiation of canine bone marrow-derived macrophages.

Wijekoon S, Bwalya EC, Fang J, Kim S, Hosoya K, Okumura M.

J Vet Med Sci. 2017 Dec 22;79(12):2030-2035. doi: 10.1292/jvms.17-0393. Epub 2017 Nov 3.

22.

Inner Blood-Retinal Barrier Dominantly Expresses Breast Cancer Resistance Protein: Comparative Quantitative Targeted Absolute Proteomics Study of CNS Barriers in Pig.

Zhang Z, Uchida Y, Hirano S, Ando D, Kubo Y, Auriola S, Akanuma SI, Hosoya KI, Urtti A, Terasaki T, Tachikawa M.

Mol Pharm. 2017 Nov 6;14(11):3729-3738. doi: 10.1021/acs.molpharmaceut.7b00493. Epub 2017 Oct 12.

PMID:
28954515
23.

Subcellular Localization of Maspin Correlates with Histone Deacetylase 1 Expression in Human Breast Cancer.

Wakahara M, Sakabe T, Kubouchi Y, Hosoya K, Hirooka Y, Yurugi Y, Nosaka K, Shiomi T, Nakamura H, Umekita Y.

Anticancer Res. 2017 Sep;37(9):5071-5077.

PMID:
28870936
24.

Involvement of Carrier-Mediated Transport at the Blood-Cerebrospinal Fluid Barrier in Spermine Clearance from Rat Brain.

Akanuma SI, Shimada H, Kubo Y, Hosoya KI.

Biol Pharm Bull. 2017;40(9):1599-1603. doi: 10.1248/bpb.b17-00394.

25.

Influx Transport of Cationic Drug at the Blood-Retinal Barrier: Impact on the Retinal Delivery of Neuroprotectants.

Kubo Y, Akanuma SI, Hosoya KI.

Biol Pharm Bull. 2017;40(8):1139-1145. doi: 10.1248/bpb.b17-00090. Review.

26.

Differentiation potential of synoviocytes derived from joints with cranial cruciate ligament rupture and medial patella luxation in dogs.

Wijekoon HMS, Toyota K, Kim S, Fang J, Bwalya EC, Hosoya K, Okumura M.

Res Vet Sci. 2017 Oct;114:370-377. doi: 10.1016/j.rvsc.2017.07.004. Epub 2017 Jul 9.

27.

Effects of pentosan polysulfate and polysulfated glycosaminoglycan on chondrogenesis of canine bone marrow-derived mesenchymal stem cells in alginate and micromass culture.

Bwalya EC, Kim S, Fang J, Wijekoon HMS, Hosoya K, Okumura M.

J Vet Med Sci. 2017 Jul 7;79(7):1182-1190. doi: 10.1292/jvms.17-0084. Epub 2017 May 27.

28.

Co-localization of microsomal prostaglandin E synthase-1 with cyclooxygenase-1 in layer II of murine placental syncytiotrophoblasts.

Inagaki M, Nishimura T, Akanuma SI, Nakanishi T, Tachikawa M, Tamai I, Hosoya KI, Nakashima E, Tomi M.

Placenta. 2017 May;53:76-82. doi: 10.1016/j.placenta.2017.04.002. Epub 2017 Apr 6.

PMID:
28487024
29.

Pentosan polysulfate inhibits IL-1β-induced iNOS, c-Jun and HIF-1α upregulation in canine articular chondrocytes.

Bwalya EC, Kim S, Fang J, Wijekoon HMS, Hosoya K, Okumura M.

PLoS One. 2017 May 4;12(5):e0177144. doi: 10.1371/journal.pone.0177144. eCollection 2017.

30.

Retina-to-Blood Transport of 1-Methyl-4-Phenylpyridinium Involves Carrier-Mediated Process at the Blood-Retinal Barrier.

Kubo Y, Yamamoto M, Matsunaga K, Usui T, Akanuma SI, Hosoya KI.

J Pharm Sci. 2017 Sep;106(9):2583-2591. doi: 10.1016/j.xphs.2017.04.028. Epub 2017 Apr 25.

PMID:
28454745
31.

Impact of surgical margins on survival of 37 dogs with massive hepatocellular carcinoma.

Matsuyama A, Takagi S, Hosoya K, Kagawa Y, Nakamura K, Deguchi T, Takiguchi M.

N Z Vet J. 2017 Sep;65(5):227-231. doi: 10.1080/00480169.2017.1319304. Epub 2017 May 8.

PMID:
28441916
32.

Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs.

Ehrhardt C, Bäckman P, Couet W, Edwards C, Forbes B, Fridén M, Gumbleton M, Hosoya KI, Kato Y, Nakanishi T, Takano M, Terasaki T, Yumoto R.

J Pharm Sci. 2017 Sep;106(9):2234-2244. doi: 10.1016/j.xphs.2017.04.011. Epub 2017 Apr 15. Review.

PMID:
28416418
33.

An ultra-specific and sensitive sandwich ELISA for imatinib using two anti-imatinib antibodies.

Saita T, Yamamoto Y, Hosoya K, Yamamoto Y, Kimura S, Narisawa Y, Shin M.

Anal Chim Acta. 2017 May 29;969:72-78. doi: 10.1016/j.aca.2017.03.034. Epub 2017 Mar 27.

PMID:
28411632
34.

Detection of KRAS Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients.

Hosoya K, Matsusaka S, Kashiwada T, Suzuki K, Ureshino N, Sato A, Miki Y, Kitera K, Hirai M, Hatake K, Kimura S, Sueoka-Aragane N.

Pathol Oncol Res. 2017 Oct;23(4):737-744. doi: 10.1007/s12253-016-0175-1. Epub 2017 Jan 5.

PMID:
28058585
35.

Blood-to-retina transport of riboflavin via RFVTs at the inner blood-retinal barrier.

Kubo Y, Yahata S, Miki S, Akanuma SI, Hosoya KI.

Drug Metab Pharmacokinet. 2017 Feb;32(1):92-99. doi: 10.1016/j.dmpk.2016.09.006. Epub 2016 Oct 8.

PMID:
27964953
36.

Impact of SLC6A Transporters in Physiological Taurine Transport at the Blood-Retinal Barrier and in the Liver.

Kubo Y, Akanuma SI, Hosoya KI.

Biol Pharm Bull. 2016;39(12):1903-1911. Review.

37.

Histamine elimination from the cerebrospinal fluid across the blood-cerebrospinal fluid barrier: involvement of plasma membrane monoamine transporter (PMAT/SLC29A4).

Usui T, Nakazawa A, Okura T, Deguchi Y, Akanuma SI, Kubo Y, Hosoya KI.

J Neurochem. 2016 Nov;139(3):408-418. doi: 10.1111/jnc.13758. Epub 2016 Sep 15.

38.

Correlation between Ultrasound Findings of Tumor Margin and Clinicopathological Findings in Patients with Invasive Ductal Carcinoma of the Breast.

Sannomiya N, Hattori Y, Ueda N, Kamida A, Koyanagi Y, Nagira H, Ikunishi S, Shimabayashi K, Hashimoto Y, Murata A, Sato K, Hirooka Y, Hosoya K, Ishiguro K, Murata Y, Hirooka Y.

Yonago Acta Med. 2016 Jun 29;59(2):163-8. eCollection 2016 Jun.

39.
40.

Development of Rapid Identification and Risk Analysis of Moniliella Spp. in Acidic Processed Foods.

Nakayama M, Hosoya K, Shimizu-Imanishi Y, Chibana H, Yaguchi T.

Biocontrol Sci. 2016;21(2):73-80. doi: 10.4265/bio.21.73.

41.

Functional expression of nicotine influx transporter in A549 human alveolar epithelial cells.

Tega Y, Yuzurihara C, Kubo Y, Akanuma SI, Ehrhardt C, Hosoya KI.

Drug Metab Pharmacokinet. 2016 Feb;31(1):99-101. doi: 10.1016/j.dmpk.2015.11.006. Epub 2015 Dec 9.

PMID:
26830082
42.

Impact of Peritoneal Dialysis Catheter Insertion by a Nephrologist: Results of a Questionnaire Survey of Patients and Nurses.

Washida N, Aikawa K, Inoue S, Kasai T, Shinozuka K, Morimoto K, Hosoya K, Hayashi K, Itoh H.

Adv Perit Dial. 2015;31:59-68.

PMID:
26714391
43.

Treatment of Gastrin-Secreting Tumor With Sustained-Release Octreotide Acetate in a Dog.

Kim S, Hosoya K, Takagi S, Okumura M.

J Am Anim Hosp Assoc. 2015 Nov-Dec;51(6):407-12. doi: 10.5326/JAAHA-MS-6270.

PMID:
26535461
44.

The role of adipose tissue asymmetric dimethylarginine/dimethylarginine dimethylaminohydrolase pathway in adipose tissue phenotype and metabolic abnormalities in subtotally nephrectomized rats.

Minakuchi H, Wakino S, Hosoya K, Sueyasu K, Hasegawa K, Shinozuka K, Yoshifuji A, Futatsugi K, Komatsu M, Kanda T, Tokuyama H, Hayashi K, Itoh H.

Nephrol Dial Transplant. 2016 Mar;31(3):413-23. doi: 10.1093/ndt/gfv367. Epub 2015 Oct 28.

PMID:
26516203
45.

Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats.

Fujii S, Setoguchi C, Kawazu K, Hosoya K.

Drug Metab Dispos. 2015 Dec;43(12):1956-9. doi: 10.1124/dmd.115.066266. Epub 2015 Oct 2.

46.
47.

Impact of Cationic Amino Acid Transporter 1 on Blood-Retinal Barrier Transport of L-Ornithine.

Kubo Y, Obata A, Akanuma S, Hosoya K.

Invest Ophthalmol Vis Sci. 2015 Sep;56(10):5925-32. doi: 10.1167/iovs.15-17398.

PMID:
26377079
48.

Clinical Significance of Microcalcifications Detection in Invasive Breast Carcinoma.

Hashimoto Y, Murata A, Miyamoto N, Takamori T, Hosoda Y, Endo Y, Kodani Y, Sato K, Hosoya K, Ishiguro K, Hirooka Y.

Yonago Acta Med. 2015 Jun;58(2):89-93. Epub 2015 Aug 18.

49.

Microcalcification of Tumor is a Predictor of Response to Neoadjuvant Chemotherapy for Invasive Breast Carcinoma.

Murata A, Sannomiya N, Miyamoto N, Ueda N, Kamida A, Koyanagi Y, Nagira H, Matsuda E, Hashimoto Y, Sato K, Hirooka Y, Hosoya K, Takagi Y, Tanaka Y, Araki K, Ishiguro K, Hirooka Y.

Yonago Acta Med. 2015 Jun;58(2):85-8. Epub 2015 Aug 18.

50.

Organic cation transporter function in different in vitro models of human lung epithelium.

Salomon JJ, Gausterer JC, Yahara T, Hosoya K, Huwer H, Hittinger M, Schneider-Daum N, Lehr CM, Ehrhardt C.

Eur J Pharm Sci. 2015 Dec 1;80:82-8. doi: 10.1016/j.ejps.2015.08.007. Epub 2015 Aug 19.

PMID:
26296865

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