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Items: 1 to 50 of 231

1.

Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design.

Marshansky V, Hosokawa H, Merkulova M, Bakulina A, Dip PV, Thaker YR, Bjargava A, Tonra JR, Ausiello DA, Grüber G.

Curr Top Membr. 2019;83:77-106. doi: 10.1016/bs.ctm.2019.01.008. Epub 2019 Mar 22.

PMID:
31196611
2.

Risk Factors and Prevalence of Deep Vein Thrombosis After the 2016 Kumamoto Earthquakes.

Sato K, Sakamoto K, Hashimoto Y, Hanzawa K, Sueta D, Kojima S, Fukuda M, Usuku H, Kihara F, Hosokawa H, Nagai Y, Nakajima M, Saito Y, Sakai K, Masunaga S, Tanaka S, Fujimoto K, Morihisa K, Noda K, Nishigami K, Nagata K, Fujisue K, Tabata N, Ando Y, Tsujita K, Ogawa H, Hokimoto S; KEEP Project.

Circ J. 2019 May 24;83(6):1342-1348. doi: 10.1253/circj.CJ-18-1369. Epub 2019 Apr 6.

3.

[Effectiveness of Steroid Rotation in a Japanese Patient with Hiccups Caused by Dexamethasone: a Case Report].

Hosokawa H, Shimoda H, Ishii T.

Yakugaku Zasshi. 2019;139(4):647-650. doi: 10.1248/yakushi.18-00192. Japanese.

4.

Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development.

Rothenberg EV, Hosokawa H, Ungerbäck J.

Front Immunol. 2019 Feb 20;10:228. doi: 10.3389/fimmu.2019.00228. eCollection 2019. Review.

5.

Solution-processed intermediate-band solar cells with lead sulfide quantum dots and lead halide perovskites.

Hosokawa H, Tamaki R, Sawada T, Okonogi A, Sato H, Ogomi Y, Hayase S, Okada Y, Yano T.

Nat Commun. 2019 Jan 10;10(1):43. doi: 10.1038/s41467-018-07655-3.

6.

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16.

Hosokawa H, Romero-Wolf M, Yui MA, Ungerbäck J, Quiloan MLG, Matsumoto M, Nakayama KI, Tanaka T, Rothenberg EV.

Nat Immunol. 2018 Dec;19(12):1427-1440. doi: 10.1038/s41590-018-0238-4. Epub 2018 Oct 30.

7.

Role of leukotriene B4 12-hydroxydehydrogenase in α-galactosylceramide-pulsed dendritic cell therapy for non-small cell lung cancer.

Tanaka K, Kanesaka Y, Takami M, Suzuki A, Hosokawa H, Onodera A, Kamata T, Nagato K, Nakayama T, Yoshino I, Motohashi S.

Biochem Biophys Res Commun. 2018 Nov 17;506(1):27-32. doi: 10.1016/j.bbrc.2018.10.048. Epub 2018 Oct 15.

PMID:
30336981
8.

Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding.

Hosokawa H, Ungerbäck J, Wang X, Matsumoto M, Nakayama KI, Cohen SM, Tanaka T, Rothenberg EV.

Immunity. 2018 Oct 16;49(4):782. doi: 10.1016/j.immuni.2018.09.019. No abstract available.

9.

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1).

Ungerbäck J, Hosokawa H, Wang X, Strid T, Williams BA, Sigvardsson M, Rothenberg EV.

Genome Res. 2018 Oct;28(10):1508-1519. doi: 10.1101/gr.231423.117. Epub 2018 Aug 31.

10.

In vivo targeted single-nucleotide editing in zebrafish.

Tanaka S, Yoshioka S, Nishida K, Hosokawa H, Kakizuka A, Maegawa S.

Sci Rep. 2018 Jul 30;8(1):11423. doi: 10.1038/s41598-018-29794-9.

11.

Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding.

Hosokawa H, Ungerbäck J, Wang X, Matsumoto M, Nakayama KI, Cohen SM, Tanaka T, Rothenberg EV.

Immunity. 2018 Jun 19;48(6):1119-1134.e7. doi: 10.1016/j.immuni.2018.04.024. Erratum in: Immunity. 2018 Oct 16;49(4):782.

12.

Do Patients With Parkinson's Disease Exhibit Reduced Cheating Behavior? A Neuropsychological Study.

Abe N, Kawasaki I, Hosokawa H, Baba T, Takeda A.

Front Neurol. 2018 May 24;9:378. doi: 10.3389/fneur.2018.00378. eCollection 2018.

13.

Toward more accurate prediction of caspase cleavage sites: a comprehensive review of current methods, tools and features.

Bao Y, Marini S, Tamura T, Kamada M, Maegawa S, Hosokawa H, Song J, Akutsu T.

Brief Bioinform. 2018 May 31. doi: 10.1093/bib/bby041. [Epub ahead of print]

PMID:
29860277
14.

Venous Thromboembolism Caused by Spending a Night in a Vehicle After an Earthquake (Night in a Vehicle After the 2016 Kumamoto Earthquake).

Sueta D, Hokimoto S, Hashimoto Y, Sakamoto K, Hosokawa H, Nishigami K, Sato K, Fujisue K, Kojima S, Takahashi T, Hanzawa K, Ogawa H, Tsujita K; Kumamoto Earthquake Thrombosis and Embolism Protection (KEEP) Project Investigators.

Can J Cardiol. 2018 Jun;34(6):813.e9-813.e10. doi: 10.1016/j.cjca.2018.01.014. Epub 2018 May 3. No abstract available. Erratum in: Can J Cardiol. 2018 Oct;34(10):1368.

PMID:
29729882
15.

Deficiency of Serotonin in Raphe Neurons and Altered Behavioral Responses in Tryptophan Hydroxylase 2-Knockout Medaka (Oryzias latipes).

Ansai S, Hosokawa H, Maegawa S, Naruse K, Washio Y, Sato K, Kinoshita M.

Zebrafish. 2017 Dec;14(6):495-507. doi: 10.1089/zeb.2017.1452. Epub 2017 Sep 21.

PMID:
28933662
16.

Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation.

Hayashizaki K, Kimura MY, Tokoyoda K, Hosokawa H, Shinoda K, Hirahara K, Ichikawa T, Onodera A, Hanazawa A, Iwamura C, Kakuta J, Muramoto K, Motohashi S, Tumes DJ, Iinuma T, Yamamoto H, Ikehara Y, Okamoto Y, Nakayama T.

Sci Immunol. 2016 Sep 16;1(3):eaaf9154. doi: 10.1126/sciimmunol.aaf9154. Epub 2016 Sep 16.

PMID:
28783682
17.

Cytokines, Transcription Factors, and the Initiation of T-Cell Development.

Hosokawa H, Rothenberg EV.

Cold Spring Harb Perspect Biol. 2018 May 1;10(5). pii: a028621. doi: 10.1101/cshperspect.a028621. Review.

18.

Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network.

Longabaugh WJR, Zeng W, Zhang JA, Hosokawa H, Jansen CS, Li L, Romero-Wolf M, Liu P, Kueh HY, Mortazavi A, Rothenberg EV.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):5800-5807. doi: 10.1073/pnas.1610617114.

19.

Three-dimensional analysis of somatic mitochondrial dynamics in fission-deficient injured motor neurons using FIB/SEM.

Tamada H, Kiryu-Seo S, Hosokawa H, Ohta K, Ishihara N, Nomura M, Mihara K, Nakamura KI, Kiyama H.

J Comp Neurol. 2017 Aug 1;525(11):2535-2548. doi: 10.1002/cne.24213. Epub 2017 Apr 21.

PMID:
28324645
20.

Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish.

Tanaka S, Hosokawa H, Weinberg ES, Maegawa S.

Dev Biol. 2017 Apr 15;424(2):189-197. doi: 10.1016/j.ydbio.2017.02.018. Epub 2017 Mar 1.

21.

Th2 Cells in Health and Disease.

Nakayama T, Hirahara K, Onodera A, Endo Y, Hosokawa H, Shinoda K, Tumes DJ, Okamoto Y.

Annu Rev Immunol. 2017 Apr 26;35:53-84. doi: 10.1146/annurev-immunol-051116-052350. Epub 2016 Nov 28. Review.

PMID:
27912316
22.

Pharmacogenetic reactivation of the original engram evokes an extinguished fear memory.

Yoshii T, Hosokawa H, Matsuo N.

Neuropharmacology. 2017 Feb;113(Pt A):1-9. doi: 10.1016/j.neuropharm.2016.09.012. Epub 2016 Sep 14.

PMID:
27639988
23.

Establishment of a new three-dimensional human epidermal model reconstructed from plucked hair follicle-derived keratinocytes.

Nakano M, Kamada N, Suehiro K, Oikawa A, Shibata C, Nakamura Y, Matsue H, Sasahara Y, Hosokawa H, Nakayama T, Nonaka K, Ohara O.

Exp Dermatol. 2016 Nov;25(11):903-906. doi: 10.1111/exd.13066. No abstract available.

PMID:
27194575
24.

An accessibility-incorporated method for accurate prediction of RNA-RNA interactions from sequence data.

Kato Y, Mori T, Sato K, Maegawa S, Hosokawa H, Akutsu T.

Bioinformatics. 2017 Jan 15;33(2):202-209. doi: 10.1093/bioinformatics/btw603. Epub 2016 Sep 23.

PMID:
27663495
25.

Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells.

Hosokawa H, Tanaka T, Endo Y, Kato M, Shinoda K, Suzuki A, Motohashi S, Matsumoto M, Nakayama KI, Nakayama T.

Nat Commun. 2016 Apr 7;7:11289. doi: 10.1038/ncomms11289.

26.

Chronic fluoxetine treatment induces anxiolytic responses and altered social behaviors in medaka, Oryzias latipes.

Ansai S, Hosokawa H, Maegawa S, Kinoshita M.

Behav Brain Res. 2016 Apr 15;303:126-36. doi: 10.1016/j.bbr.2016.01.050. Epub 2016 Jan 25.

PMID:
26821288
27.

Colorimetric Humidity and Solvent Recognition Based on a Cation-Exchange Clay Mineral Incorporating Nickel(II)-Chelate Complexes.

Hosokawa H, Mochida T.

Langmuir. 2015 Dec 1;31(47):13048-53. doi: 10.1021/acs.langmuir.5b03709. Epub 2015 Nov 19.

PMID:
26542108
28.

Determining Associations between Human Diseases and non-coding RNAs with Critical Roles in Network Control.

Kagami H, Akutsu T, Maegawa S, Hosokawa H, Nacher JC.

Sci Rep. 2015 Oct 13;5:14577. doi: 10.1038/srep14577.

29.

Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis.

Watanabe Y, Kazuki Y, Kazuki K, Ebiki M, Nakanishi M, Nakamura K, Yoshida Yamakawa M, Hosokawa H, Ohbayashi T, Oshimura M, Nakashima K.

Mol Ther Nucleic Acids. 2015 Oct 6;4:e253. doi: 10.1038/mtna.2015.28.

30.

Distribution of transient receptor potential melastatin-8-containing nerve fibers in rat oral and craniofacial structures.

Yajima T, Sato T, Hosokawa H, Kondo T, Saito M, Shimauchi H, Ichikawa H.

Ann Anat. 2015 Sep;201:1-5. doi: 10.1016/j.aanat.2015.04.003. Epub 2015 Apr 25.

PMID:
25978347
31.

A Novel Method for Rearing Zebrafish by Using Freshwater Rotifers (Brachionus calyciflorus).

Aoyama Y, Moriya N, Tanaka S, Taniguchi T, Hosokawa H, Maegawa S.

Zebrafish. 2015 Aug;12(4):288-95. doi: 10.1089/zeb.2014.1032. Epub 2015 May 4.

32.

Methylation of Gata3 protein at Arg-261 regulates transactivation of the Il5 gene in T helper 2 cells.

Hosokawa H, Kato M, Tohyama H, Tamaki Y, Endo Y, Kimura MY, Tumes DJ, Motohashi S, Matsumoto M, Nakayama KI, Tanaka T, Nakayama T.

J Biol Chem. 2015 May 22;290(21):13095-103. doi: 10.1074/jbc.M114.621524. Epub 2015 Apr 10.

33.

Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development.

Mishima Y, Wang C, Miyagi S, Saraya A, Hosokawa H, Mochizuki-Kashio M, Nakajima-Takagi Y, Koide S, Negishi M, Sashida G, Naito T, Ishikura T, Onodera A, Nakayama T, Tenen DG, Yamaguchi N, Koseki H, Taniuchi I, Iwama A.

Nat Commun. 2014 Dec 18;5:5872. doi: 10.1038/ncomms6872.

34.

Colorimetric solvent indicators based on Nafion membranes incorporating nickel(II)-chelate complexes.

Hosokawa H, Funasako Y, Mochida T.

Chemistry. 2014 Nov 10;20(46):15014-20. doi: 10.1002/chem.201403996. Epub 2014 Oct 13.

PMID:
25308167
35.

The long-term use of soap does not affect the pH-maintenance mechanism of human skin.

Takagi Y, Kaneda K, Miyaki M, Matsuo K, Kawada H, Hosokawa H.

Skin Res Technol. 2015 May;21(2):144-8. doi: 10.1111/srt.12170. Epub 2014 Jul 30.

PMID:
25073884
36.

Transverse nasal lesions: a Japanese study.

Hosokawa H, Hosokawa K.

J Dermatol. 2014 Jun;41(6):551-2. doi: 10.1111/1346-8138.12507. No abstract available.

PMID:
24909218
37.

Ionic liquids from cationic palladium(II) chelate complexes: preparation, thermal properties, and crystal structures.

Hosokawa H, Funasako Y, Mochida T.

Dalton Trans. 2014 May 14;43(18):6864-9. doi: 10.1039/c4dt00192c.

PMID:
24658643
38.

Elastic rotation of Escherichia coli F(O)F(1) having ε subunit fused with cytochrome b(562) or flavodoxin reductase.

Oka H, Hosokawa H, Nakanishi-Matsui M, Dunn SD, Futai M, Iwamoto-Kihara A.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):889-93. doi: 10.1016/j.bbrc.2014.03.021. Epub 2014 Mar 13.

PMID:
24631905
39.

Nanoparticulation of BCG-CWS for application to bladder cancer therapy.

Nakamura T, Fukiage M, Higuchi M, Nakaya A, Yano I, Miyazaki J, Nishiyama H, Akaza H, Ito T, Hosokawa H, Nakayama T, Harashima H.

J Control Release. 2014 Feb 28;176:44-53. doi: 10.1016/j.jconrel.2013.12.027. Epub 2013 Dec 31.

40.

The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells.

Tumes DJ, Onodera A, Suzuki A, Shinoda K, Endo Y, Iwamura C, Hosokawa H, Koseki H, Tokoyoda K, Suzuki Y, Motohashi S, Nakayama T.

Immunity. 2013 Nov 14;39(5):819-32. doi: 10.1016/j.immuni.2013.09.012.

41.

Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.

Hosokawa H, Tanaka T, Kato M, Shinoda K, Tohyama H, Hanazawa A, Tamaki Y, Hirahara K, Yagi R, Sakikawa I, Morita A, Nagira M, Poyurovsky MV, Suzuki Y, Motohashi S, Nakayama T.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18626-31. doi: 10.1073/pnas.1311100110. Epub 2013 Oct 28.

42.

Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity.

Sasaki T, Onodera A, Hosokawa H, Watanabe Y, Horiuchi S, Yamashita J, Tanaka H, Ogawa Y, Suzuki Y, Nakayama T.

PLoS One. 2013 Jun 18;8(6):e66468. doi: 10.1371/journal.pone.0066468. Print 2013.

43.

A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency.

Jabara HH, Ohsumi T, Chou J, Massaad MJ, Benson H, Megarbane A, Chouery E, Mikhael R, Gorka O, Gewies A, Portales P, Nakayama T, Hosokawa H, Revy P, Herrod H, Le Deist F, Lefranc G, Ruland J, Geha RS.

J Allergy Clin Immunol. 2013 Jul;132(1):151-8. doi: 10.1016/j.jaci.2013.04.047. Epub 2013 May 31. Erratum in: J Allergy Clin Immunol. 2013 Sep;132(3):773. J Allergy Clin Immunol. 2013 Sep;132(3):773.

44.

Intragastric administration of allyl isothiocyanate reduces hyperglycemia in intraperitoneal glucose tolerance test (IPGTT) by enhancing blood glucose consumption in mice.

Mori N, Kurata M, Yamazaki H, Hosokawa H, Nadamoto T, Inoue K, Fushiki T.

J Nutr Sci Vitaminol (Tokyo). 2013;59(1):56-63.

45.

Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity.

Hosokawa H, Tanaka T, Suzuki Y, Iwamura C, Ohkubo S, Endoh K, Kato M, Endo Y, Onodera A, Tumes DJ, Kanai A, Sugano S, Nakayama T.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4691-6. doi: 10.1073/pnas.1220865110. Epub 2013 Mar 7.

46.

The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase) and cytohesin-2.

Hosokawa H, Dip PV, Merkulova M, Bakulina A, Zhuang Z, Khatri A, Jian X, Keating SM, Bueler SA, Rubinstein JL, Randazzo PA, Ausiello DA, Grüber G, Marshansky V.

J Biol Chem. 2013 Feb 22;288(8):5896-913. doi: 10.1074/jbc.M112.409169. Epub 2013 Jan 3.

47.

High-resolution single-molecule characterization of the enzymatic states in Escherichia coli F1-ATPase.

Bilyard T, Nakanishi-Matsui M, Steel BC, Pilizota T, Nord AL, Hosokawa H, Futai M, Berry RM.

Philos Trans R Soc Lond B Biol Sci. 2012 Dec 24;368(1611):20120023. doi: 10.1098/rstb.2012.0023. Print 2013 Feb 5.

48.

The distribution of transient receptor potential melastatin-8 in the rat soft palate, epiglottis, and pharynx.

Sato T, Fujita M, Kano M, Hosokawa H, Kondo T, Suzuki T, Kasahara E, Shoji N, Sasano T, Ichikawa H.

Cell Mol Neurobiol. 2013 Mar;33(2):161-5. doi: 10.1007/s10571-012-9888-1. Epub 2012 Nov 7.

PMID:
23132652
49.

Effectiveness and Safety of a Multicenter Extension and Retreatment Trial of Gel-200 in Patients with Knee Osteoarthritis.

Strand V, Baraf HS, Lavin PT, Lim S, Hosokawa H.

Cartilage. 2012 Oct;3(4):297-304. doi: 10.1177/1947603512451024.

50.

The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation.

Kuwahara M, Yamashita M, Shinoda K, Tofukuji S, Onodera A, Shinnakasu R, Motohashi S, Hosokawa H, Tumes D, Iwamura C, Lefebvre V, Nakayama T.

Nat Immunol. 2012 Jul 1;13(8):778-86. doi: 10.1038/ni.2362.

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