Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 58

1.

Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells.

Huo J, Xu Z, Hosoe K, Kubo H, Miyahara H, Dai J, Mori M, Sawashita J, Higuchi K.

Oxid Med Cell Longev. 2018 Jul 8;2018:3181759. doi: 10.1155/2018/3181759. eCollection 2018.

2.

Effects of Pediococcus acidilactici R037 on Serum Triglyceride Levels in Mice and Rats after Oral Administration.

Ueda T, Tategaki A, Hamada K, Kishida H, Hosoe K, Morikawa H, Nakagawa K.

J Nutr Sci Vitaminol (Tokyo). 2018;64(1):41-47. doi: 10.3177/jnsv.64.41.

3.

Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition.

Xu Z, Huo J, Ding X, Yang M, Li L, Dai J, Hosoe K, Kubo H, Mori M, Higuchi K, Sawashita J.

Sci Rep. 2017 Aug 15;7(1):8253. doi: 10.1038/s41598-017-08899-7.

4.

Electrochemical lithium-ion storage properties of quinone molecules encapsulated in single-walled carbon nanotubes.

Ishii Y, Tashiro K, Hosoe K, Al-Zubaidi A, Kawasaki S.

Phys Chem Chem Phys. 2016 Apr 21;18(15):10411-8. doi: 10.1039/c6cp01103a. Epub 2016 Mar 31.

PMID:
27030581
5.

Enhancement of Fat Oxidation by Licorice Flavonoid Oil in Healthy Humans during Light Exercise.

Mori N, Nakanishi S, Shiomi S, Kiyokawa S, Kakimoto S, Nakagawa K, Hosoe K, Minami K, Nadamoto T.

J Nutr Sci Vitaminol (Tokyo). 2015;61(5):406-16. doi: 10.3177/jnsv.61.406.

6.

Stability of ubiquinol-10 (reduced form of coenzyme Q10 ) in human blood.

Matsuo K, Kasai K, Hosoe K, Funahashi I.

Biomed Chromatogr. 2016 Apr;30(4):500-2. doi: 10.1002/bmc.3570. Epub 2015 Aug 31.

PMID:
26248527
7.

Highly site-selective transvascular drug delivery by the use of nanosecond pulsed laser-induced photomechanical waves.

Sato S, Yoshida K, Kawauchi S, Hosoe K, Akutsu Y, Fujimoto N, Nawashiro H, Terakawa M.

J Control Release. 2014 Oct 28;192:228-35. doi: 10.1016/j.jconrel.2014.07.048. Epub 2014 Aug 4.

PMID:
25102403
8.

Ubiquinol-10 supplementation activates mitochondria functions to decelerate senescence in senescence-accelerated mice.

Tian G, Sawashita J, Kubo H, Nishio SY, Hashimoto S, Suzuki N, Yoshimura H, Tsuruoka M, Wang Y, Liu Y, Luo H, Xu Z, Mori M, Kitano M, Hosoe K, Takeda T, Usami S, Higuchi K.

Antioxid Redox Signal. 2014 Jun 1;20(16):2606-20. doi: 10.1089/ars.2013.5406. Epub 2013 Dec 14.

9.

Ubiquinol affects the expression of genes involved in PPARα signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice.

Schmelzer C, Kitano M, Hosoe K, Döring F.

J Clin Biochem Nutr. 2012 Mar;50(2):119-26. doi: 10.3164/jcbn.11-19. Epub 2011 Nov 11.

10.

Oral repeated-dose toxicity studies of coenzyme Q10 in beagle dogs.

Yerramilli-Rao P, Beal MF, Watanabe D, Kieburtz K, Blieck EA, Kitano M, Hosoe K, Funahashi I, Cudkowicz ME.

Int J Toxicol. 2012 Jan-Feb;31(1):58-69. doi: 10.1177/1091581811425256. Epub 2012 Jan 20.

11.

Change in sleep state of the elderly before and after cataract surgery.

Tanaka M, Hosoe K, Hamada T, Morita T.

J Physiol Anthropol. 2010;29(6):219-24.

12.

Inhibition by licorice flavonoid oil of glutathione S-transferase-positive foci in the medium-term rat hepatocarcinogenesis bioassay.

Nakagawa K, Hosoe K, Hidaka T, Nabae K, Kawabe M, Kitano M.

Nutr Res. 2010 Jan;30(1):74-81. doi: 10.1016/j.nutres.2009.12.005.

PMID:
20116663
13.

Supplementation with the reduced form of Coenzyme Q10 decelerates phenotypic characteristics of senescence and induces a peroxisome proliferator-activated receptor-alpha gene expression signature in SAMP1 mice.

Schmelzer C, Kubo H, Mori M, Sawashita J, Kitano M, Hosoe K, Boomgaarden I, Döring F, Higuchi K.

Mol Nutr Food Res. 2010 Jun;54(6):805-15. doi: 10.1002/mnfr.200900155.

PMID:
19960455
14.

Effects of ubiquinol-10 on microRNA-146a expression in vitro and in vivo.

Schmelzer C, Kitano M, Rimbach G, Niklowitz P, Menke T, Hosoe K, Döring F.

Mediators Inflamm. 2009;2009:415437. doi: 10.1155/2009/415437. Epub 2009 Apr 16.

15.

Safety assessment of coenzyme Q10 (CoQ10).

Hidaka T, Fujii K, Funahashi I, Fukutomi N, Hosoe K.

Biofactors. 2008;32(1-4):199-208. Review.

PMID:
19096117
16.

Genotoxicity studies on licorice flavonoid oil (LFO).

Nakagawa K, Hidaka T, Kitano M, Asakura M, Kamigaito T, Noguchi T, Hosoe K.

Food Chem Toxicol. 2008 Jul;46(7):2525-32. doi: 10.1016/j.fct.2008.04.008. Epub 2008 Apr 14.

PMID:
18502556
17.

90-Day repeated-dose toxicity study of licorice flavonoid oil (LFO) in rats.

Nakagawa K, Kitano M, Kishida H, Hidaka T, Nabae K, Kawabe M, Hosoe K.

Food Chem Toxicol. 2008 Jul;46(7):2349-57. doi: 10.1016/j.fct.2008.03.015. Epub 2008 Mar 21.

PMID:
18448224
18.

Subchronic oral toxicity of ubiquinol in rats and dogs.

Kitano M, Watanabe D, Oda S, Kubo H, Kishida H, Fujii K, Kitahara M, Hosoe K.

Int J Toxicol. 2008 Mar-Apr;27(2):189-215. doi: 10.1080/10915810801978060.

PMID:
18404543
19.

Evaluation of the mutagenic and genotoxic potential of ubiquinol.

Kitano M, Mizuhashi F, Kubo H, Kishida H, Fujii K, Kitahara M, Hosoe K.

Int J Toxicol. 2007 Nov-Dec;26(6):533-44.

PMID:
18066969
20.

Absorption of dietary licorice isoflavan glabridin to blood circulation in rats.

Ito C, Oi N, Hashimoto T, Nakabayashi H, Aoki F, Tominaga Y, Yokota S, Hosoe K, Kanazawa K.

J Nutr Sci Vitaminol (Tokyo). 2007 Aug;53(4):358-65.

21.

Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers.

Hosoe K, Kitano M, Kishida H, Kubo H, Fujii K, Kitahara M.

Regul Toxicol Pharmacol. 2007 Feb;47(1):19-28. Epub 2006 Aug 21.

PMID:
16919858
22.

Possible tumor development from double positive foci for TGF-alpha and GST-P observed in early stages on rat hepatocarcinogenesis.

Kitano M, Wada J, Ariki Y, Kato M, Wanibuchi H, Morimura K, Hidaka T, Hosoe K, Fukushima S.

Cancer Sci. 2006 Jun;97(6):478-83.

23.

Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice.

Yan J, Fujii K, Yao J, Kishida H, Hosoe K, Sawashita J, Takeda T, Mori M, Higuchi K.

Exp Gerontol. 2006 Feb;41(2):130-40. Epub 2006 Jan 4.

PMID:
16387461
24.

Evaluation of the mutagenic potential of ubidecarenone using three short-term assays.

Kitano M, Hosoe K, Fukutomi N, Hidaka T, Ohta R, Yamakage K, Hara T.

Food Chem Toxicol. 2006 Mar;44(3):364-70. Epub 2005 Sep 27.

PMID:
16198039
25.

Intra- and interlaboratory calibration of the DR CALUX bioassay for the analysis of dioxins and dioxin-like chemicals in sediments.

Besselink HT, Schipper C, Klamer H, Leonards P, Verhaar H, Felzel E, Murk AJ, Thain J, Hosoe K, Schoeters G, Legler J, Brouwer B.

Environ Toxicol Chem. 2004 Dec;23(12):2781-9.

PMID:
15648750
26.

28-Day repeated dose toxicity study of dried microorganism in rats.

Kitano M, Hosoe K, Fukutomi N, Hidaka T, Imai N, Kawabe M.

Food Chem Toxicol. 2004 Nov;42(11):1817-24.

PMID:
15350679
27.
28.

Low-temperature thermal decomposition of dioxin-like compounds in fly ash: combination of chemical analysis with in vitro bioassays (EROD and DR-CALUX).

Behnisch PA, Hosoe K, Shiozaki K, Ozaki H, Nakamura K, Sakai S.

Environ Sci Technol. 2002 Dec 1;36(23):5211-7.

PMID:
12523440
29.

Melting and incineration plants of municipal waste. Chemical and biochemical diagnosis of thermal processing samples (emission, residues).

Behnisch PA, Hosoe K, Shiozaki K, Kiryu T, Komatsu K, Schramm KW, Sakai S.

Environ Sci Pollut Res Int. 2002;9(5):337-44.

PMID:
12391810
30.

Screening of dioxin-like toxicity equivalents for various matrices with wildtype and recombinant rat hepatoma H4IIE cells.

Behnisch PA, Hosoe K, Brouwer A, Sakai S.

Toxicol Sci. 2002 Sep;69(1):125-30.

PMID:
12215666
31.
32.

Bioanalytical screening methods for dioxins and dioxin-like compounds a review of bioassay/biomarker technology.

Behnisch PA, Hosoe K, Sakai S.

Environ Int. 2001 Nov;27(5):413-39. Review.

PMID:
11757855
33.

Identification of enzymes responsible for rifalazil metabolism in human liver microsomes.

Mae T, Inaba T, Konishi E, Hosoe K, Hidaka T.

Xenobiotica. 2000 Jun;30(6):565-74.

PMID:
10923859
34.

Isolation and identification of major metabolites of rifalazil in mouse and human.

Mae T, Konishi E, Hosoe K, Hidaka T.

Xenobiotica. 1999 Nov;29(11):1073-87.

PMID:
10598743
35.

Effect of a new rifamycin derivative, rifalazil, on liver microsomal enzyme induction in rat and dog.

Mae T, Hosoe K, Yamamoto T, Hidaka T, Ohashi T, Kleeman JM, Adams PE.

Xenobiotica. 1998 Aug;28(8):759-66.

PMID:
9741954
36.

Pharmacokinetics of KRM-1648, a new benzoxazinorifamycin, in rats and dogs.

Hosoe K, Mae T, Konishi E, Fujii K, Yamashita K, Yamane T, Hidaka T, Ohashi T.

Antimicrob Agents Chemother. 1996 Dec;40(12):2749-55.

37.

In vitro metabolism of a rifamycin derivative by animal and human liver microsomes, whole blood and expressed human CYP3A isoform.

Mae T, Hosoe K, Fujii K, Yamashita K, Yamane T, Hidaka T, Ohashi T.

Xenobiotica. 1996 Aug;26(8):793-802.

PMID:
8879143
38.

Identification and antimicrobial activity of urinary metabolites of a rifamycin derivative in dog.

Hosoe K, Mae T, Yamashita K, Fujii K, Yamane T, Hidaka T, Ohashi T.

Xenobiotica. 1996 Mar;26(3):321-32.

PMID:
8730923
39.

In vitro and in vivo activities of the benzoxazinorifamycin KRM-1648 against Mycobacterium tuberculosis.

Hirata T, Saito H, Tomioka H, Sato K, Jidoi J, Hosoe K, Hidaka T.

Antimicrob Agents Chemother. 1995 Oct;39(10):2295-303.

40.

Mechanism of action of antimycobacterial activity of the new benzoxazinorifamycin KRM-1648.

Fujii K, Saito H, Tomioka H, Mae T, Hosoe K.

Antimicrob Agents Chemother. 1995 Jul;39(7):1489-92.

42.

Synthesis and biological activity of 3'-hydroxy-5'-aminobenzoxazinorifamycin derivatives.

Yamane T, Hashizume T, Yamashita K, Konishi E, Hosoe K, Hidaka T, Watanabe K, Kawaharada H, Yamamoto T, Kuze F.

Chem Pharm Bull (Tokyo). 1993 Jan;41(1):148-55.

PMID:
8448815
44.

Synthesis and biological activity of 5'-aminobenzoxazinorifamycin derivatives.

Yamane T, Hashizume T, Yamashita K, Hosoe K, Hidaka T, Watanabe K, Kawaharada H, Kudoh S.

Chem Pharm Bull (Tokyo). 1992 Oct;40(10):2707-11.

PMID:
1464100
45.

In vitro and in vivo activities of KRM-1648, a newly synthesized benzoxazinorifamycin, against Mycobacterium marinum.

Yamamoto Y, Saito H, Tomioka H, Sato K, Yamane T, Yamashita K, Hosoe K, Hidaka T.

Zentralbl Bakteriol. 1992 Jul;277(2):204-9.

PMID:
1520979
46.

Chemotherapeutic efficacy of a newly synthesized benzoxazinorifamycin, KRM-1648, against Mycobacterium avium complex infection induced in mice.

Tomioka H, Saito H, Sato K, Yamane T, Yamashita K, Hosoe K, Fujii K, Hidaka T.

Antimicrob Agents Chemother. 1992 Feb;36(2):387-93.

47.

In vitro antimycobacterial activities of newly synthesized benzoxazinorifamycins.

Saito H, Tomioka H, Sato K, Emori M, Yamane T, Yamashita K, Hosoe K, Hidaka T.

Antimicrob Agents Chemother. 1991 Mar;35(3):542-7.

48.

Preparation of new 7-hydroxyguanine derivatives and their biological activities.

Kitahara M, Shinjyo K, Fukae M, Hosoe K, Shiraishi T, Ishii K, Watanabe K, Kawaharada H.

J Antibiot (Tokyo). 1990 Apr;43(4):352-6.

50.

Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.

Hidaka T, Hosoe K, Yamashita T, Watanabe K, Hiramatsu Y, Fujimura H.

J Pharm Pharmacol. 1986 Oct;38(10):748-53.

PMID:
2878995

Supplemental Content

Support Center