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Items: 23


A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study of a Replication-Defective Herpes Simplex Virus 2 Vaccine, HSV529, in Adults With or Without HSV Infection.

Dropulic LK, Oestreich MC, Pietz HL, Laing KJ, Hunsberger S, Lumbard K, Garabedian D, Turk SP, Chen A, Hornung RL, Seshadri C, Smith MT, Hosken NA, Phogat S, Chang LJ, Koelle DM, Wang K, Cohen JI.

J Infect Dis. 2019 May 6. pii: jiz225. doi: 10.1093/infdis/jiz225. [Epub ahead of print]


Safety and immunogenicity of a pentavalent meningococcal conjugate vaccine containing serogroups A, C, Y, W, and X in healthy adults: a phase 1, single-centre, double-blind, randomised, controlled study.

Chen WH, Neuzil KM, Boyce CR, Pasetti MF, Reymann MK, Martellet L, Hosken N, LaForce FM, Dhere RM, Pisal SS, Chaudhari A, Kulkarni PS, Borrow R, Findlow H, Brown V, McDonough ML, Dally L, Alderson MR.

Lancet Infect Dis. 2018 Oct;18(10):1088-1096. doi: 10.1016/S1473-3099(18)30400-6. Epub 2018 Aug 14.


A multi-laboratory study of diverse RSV neutralization assays indicates feasibility for harmonization with an international standard.

Hosken N, Plikaytis B, Trujillo C, Mahmood K, Higgins D; Participating Laboratories Working Group.

Vaccine. 2017 May 25;35(23):3082-3088. doi: 10.1016/j.vaccine.2017.04.053. Epub 2017 May 2.


Stability of live attenuated rotavirus vaccine with selected preservatives and primary containers.

Lal M, Jarrahian C, Zhu C, Hosken NA, McClurkan CL, Koelle DM, Saxon E, Roehrig A, Zehrung D, Chen D.

Vaccine. 2016 May 11;34(22):2483-9. doi: 10.1016/j.vaccine.2016.03.093. Epub 2016 Apr 13.


Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system.

White JA, Blum JS, Hosken NA, Marshak JO, Duncan L, Zhu C, Norton EB, Clements JD, Koelle DM, Chen D, Weldon WC, Oberste MS, Lal M.

Hum Vaccin Immunother. 2014;10(12):3611-21. doi: 10.4161/hv.32253.


A role for IL-27 in limiting T regulatory cell populations.

Wojno ED, Hosken N, Stumhofer JS, O'Hara AC, Mauldin E, Fang Q, Turka LA, Levin SD, Hunter CA.

J Immunol. 2011 Jul 1;187(1):266-73. doi: 10.4049/jimmunol.1004182. Epub 2011 May 27.


A role for IL-27p28 as an antagonist of gp130-mediated signaling.

Stumhofer JS, Tait ED, Quinn WJ 3rd, Hosken N, Spudy B, Goenka R, Fielding CA, O'Hara AC, Chen Y, Jones ML, Saris CJ, Rose-John S, Cua DJ, Jones SA, Elloso MM, Grötzinger J, Cancro MP, Levin SD, Hunter CA.

Nat Immunol. 2010 Dec;11(12):1119-26. doi: 10.1038/ni.1957. Epub 2010 Nov 7.


Diversity of the CD8+ T-cell response to herpes simplex virus type 2 proteins among persons with genital herpes.

Hosken N, McGowan P, Meier A, Koelle DM, Sleath P, Wagener F, Elliott M, Grabstein K, Posavad C, Corey L.

J Virol. 2006 Jun;80(11):5509-15.


Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects.

Sylwester AW, Mitchell BL, Edgar JB, Taormina C, Pelte C, Ruchti F, Sleath PR, Grabstein KH, Hosken NA, Kern F, Nelson JA, Picker LJ.

J Exp Med. 2005 Sep 5;202(5):673-85.


Development of a therapeutic vaccine for HSV-2.

Hosken NA.

Vaccine. 2005 Mar 18;23(17-18):2395-8.


Immunodominance among herpes simplex virus-specific CD8 T cells expressing a tissue-specific homing receptor.

Koelle DM, Liu Z, McClurkan CL, Cevallos RC, Vieira J, Hosken NA, Meseda CA, Snow DC, Wald A, Corey L.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12899-904. Epub 2003 Oct 17.


T cell immunity to herpes simplex viruses in seronegative subjects: silent infection or acquired immunity?

Posavad CM, Wald A, Hosken N, Huang ML, Koelle DM, Ashley RL, Corey L.

J Immunol. 2003 Apr 15;170(8):4380-8.


Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3).

Grimaldi JC, Yu NX, Grunig G, Seymour BW, Cottrez F, Robinson DS, Hosken N, Ferlin WG, Wu X, Soto H, O'Garra A, Howard MC, Coffman RL.

J Leukoc Biol. 1999 Jun;65(6):846-53.


Reversibility of T helper 1 and 2 populations is lost after long-term stimulation.

Murphy E, Shibuya K, Hosken N, Openshaw P, Maino V, Davis K, Murphy K, O'Garra A.

J Exp Med. 1996 Mar 1;183(3):901-13.


The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.

Hosken NA, Shibuya K, Heath AW, Murphy KM, O'Garra A.

J Exp Med. 1995 Nov 1;182(5):1579-84.


Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations.

Openshaw P, Murphy EE, Hosken NA, Maino V, Davis K, Murphy K, O'Garra A.

J Exp Med. 1995 Nov 1;182(5):1357-67.


The role of macrophage- and dendritic cell-derived IL12 in Th1 phenotype development.

O'Garra A, Hosken N, Macatonia S, Wenner CA, Murphy K.

Res Immunol. 1995 Sep-Oct;146(7-8):466-72. Review. No abstract available.


Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

Macatonia SE, Hosken NA, Litton M, Vieira P, Hsieh CS, Culpepper JA, Wysocka M, Trinchieri G, Murphy KM, O'Garra A.

J Immunol. 1995 May 15;154(10):5071-9.


Defective presentation of endogenous antigen by a cell line expressing class I molecules.

Hosken NA, Bevan MJ.

Science. 1990 Apr 20;248(4953):367-70.


A conserved tripeptide sorts proteins to peroxisomes.

Gould SJ, Keller GA, Hosken N, Wilkinson J, Subramani S.

J Cell Biol. 1989 May;108(5):1657-64.


Class I-restricted presentation occurs without internalization or processing of exogenous antigenic peptides.

Hosken NA, Bevan MJ, Carbone FR.

J Immunol. 1989 Feb 15;142(4):1079-83.


Class I MHC-restricted cytotoxic responses to soluble protein antigen.

Carbone FR, Hosken NA, Moore MW, Bevan MJ.

Cold Spring Harb Symp Quant Biol. 1989;54 Pt 1:551-5. Review. No abstract available.


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