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Items: 1 to 50 of 584

1.

New entry to the enantioselective formation of substituted cyclohexenes bearing an all-carbon quaternary stereogenic center.

Komine K, Urayama Y, Hosaka T, Fukuda H, Hatakeyama S, Ishihara J.

Chirality. 2020 Jan 20. doi: 10.1002/chir.23173. [Epub ahead of print]

PMID:
31957912
2.

Research Development on K-Ion Batteries.

Hosaka T, Kubota K, Hameed AS, Komaba S.

Chem Rev. 2020 Jan 15. doi: 10.1021/acs.chemrev.9b00463. [Epub ahead of print]

PMID:
31939297
3.

A putative mechanism underlying secondary metabolite overproduction by Streptomyces strains with a 23S rRNA mutation conferring erythromycin resistance.

Hoshino K, Imai Y, Mukai K, Hamauzu R, Ochi K, Hosaka T.

Appl Microbiol Biotechnol. 2020 Jan 10. doi: 10.1007/s00253-019-10288-1. [Epub ahead of print]

PMID:
31925486
4.

Circulating MicroRNA-122 and Fibrosis Stage Predict Mortality of Japanese Patients With Histopathologically Confirmed NAFLD.

Akuta N, Kawamura Y, Arase Y, Saitoh S, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Suzuki Y, Suzuki F, Ikeda K, Kumada H.

Hepatol Commun. 2019 Nov 5;4(1):66-76. doi: 10.1002/hep4.1445. eCollection 2020 Jan.

5.

Application of cytochrome P450 reactivity on the characterization of chemical compounds and its association with repeated-dose toxicity.

Watanabe M, Sasaki T, Takeshita JI, Kushida M, Shimizu Y, Oki H, Kitsunai Y, Nakayama H, Saruhashi H, Ogura R, Shizu R, Hosaka T, Yoshinari K.

Toxicol Appl Pharmacol. 2019 Dec 10;388:114854. doi: 10.1016/j.taap.2019.114854. [Epub ahead of print]

PMID:
31836524
6.

Advantage of liver stiffness measurement before and after direct-acting antiviral therapy to predict hepatocellular carcinoma and exacerbation of esophageal varices in chronic hepatitis C.

Ogasawara N, Saitoh S, Akuta N, Sezaki H, Suzuki F, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 Nov 30. doi: 10.1111/hepr.13467. [Epub ahead of print]

PMID:
31785120
7.

Poorly Differentiated Hepatocellular Carcinoma in a Low-risk Patient with an Otherwise Normal Liver.

Ogasawara N, Saitoh S, Denpou H, Kinowaki K, Akuta N, Suzuki F, Hashimoto M, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Kobayashi M, Suzuki Y, Arase Y, Ikeda K, Fujii T, Kumada H.

Intern Med. 2019 Oct 17. doi: 10.2169/internalmedicine.3577-19. [Epub ahead of print]

8.

Effects of a structured group intervention on obesity among breast cancer survivors.

Suzuki H, Seki A, Hosaka T, Matsumoto N, Tomita M, Takahashi M, Yamauchi H.

Breast Cancer. 2019 Oct 15. doi: 10.1007/s12282-019-01013-x. [Epub ahead of print]

PMID:
31617073
9.

A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators.

Needham DM, Yoshizawa S, Hosaka T, Poirier C, Choi CJ, Hehenberger E, Irwin NAT, Wilken S, Yung CM, Bachy C, Kurihara R, Nakajima Y, Kojima K, Kimura-Someya T, Leonard G, Malmstrom RR, Mende DR, Olson DK, Sudo Y, Sudek S, Richards TA, DeLong EF, Keeling PJ, Santoro AE, Shirouzu M, Iwasaki W, Worden AZ.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20574-20583. doi: 10.1073/pnas.1907517116. Epub 2019 Sep 23.

10.

Predictors of Insulin Secretion in Japanese Patients with Histopathologically-confirmed Non-alcoholic Fatty Liver Disease.

Akuta N, Kawamura Y, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Intern Med. 2019 Sep 18. doi: 10.2169/internalmedicine.3555-19. [Epub ahead of print]

11.

Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism.

Abe T, Shizu R, Sasaki T, Shimizu Y, Hosaka T, Kodama S, Matsuzawa A, Yoshinari K.

J Pharmacol Exp Ther. 2019 Dec;371(3):590-601. doi: 10.1124/jpet.119.258632. Epub 2019 Sep 18.

PMID:
31533970
12.

[Cardiac Strangulation Induced by Epicardial Pacemaker Leads Causing Heart Failure;Report of a Case].

Hosaka T, Ozawa T, Katayama Y, Shiono N, Isobe S, Kameda T, Nunoi Y, Okuma S, Hara M, Masuhara H, Fujii T, Watanabe Y.

Kyobu Geka. 2019 Sep;72(9):712-715. Japanese.

PMID:
31506415
13.

Steroid pulse therapy of radiological disease activity without clinical relapse in CLIPPERS.

Hosaka T, Nakamagoe K, Tozaka N, Aizawa S, Tamaoka A.

Neurol Sci. 2019 Sep 3. doi: 10.1007/s10072-019-04064-2. [Epub ahead of print] No abstract available.

PMID:
31482246
14.

GDF-15, a mitochondrial disease biomarker, is associated with the severity of multiple sclerosis.

Nohara S, Ishii A, Yamamoto F, Yanagiha K, Moriyama T, Tozaka N, Miyake Z, Yatsuga S, Koga Y, Hosaka T, Terada M, Yamaguchi T, Aizawa S, Mamada N, Tsuji H, Tomidokoro Y, Nakamagoe K, Ishii K, Watanabe M, Tamaoka A.

J Neurol Sci. 2019 Oct 15;405:116429. doi: 10.1016/j.jns.2019.116429. Epub 2019 Aug 22.

PMID:
31476622
15.

Long-term outcome of hepatocellular carcinoma occurrence, esophageal varices exacerbation, and mortality in hepatitis C virus-related liver cirrhosis after interferon-based therapy.

Ogasawara N, Saitoh S, Akuta N, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Kobayashi M, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 Dec;49(12):1441-1450. doi: 10.1111/hepr.13418. Epub 2019 Oct 9.

PMID:
31373093
16.

Real-world effects of long-term rifaximin treatment for Japanese patients with hepatic encephalopathy.

Suzuki H, Sezaki H, Suzuki F, Kasuya K, Sano T, Fujiyama S, Kawamura Y, Hosaka T, Akuta N, Saitoh S, Kobayashi M, Arase Y, Ikeda K, Suzuki Y, Kumada H.

Hepatol Res. 2019 Dec;49(12):1406-1413. doi: 10.1111/hepr.13415. Epub 2019 Aug 9.

PMID:
31347756
17.

Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro.

Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K.

Drug Metab Pharmacokinet. 2019 Aug;34(4):272-279. doi: 10.1016/j.dmpk.2019.04.005. Epub 2019 Apr 19.

PMID:
31280915
18.

Abnormal glucose tolerance in a patient with pheochromocytoma and ACTH-independent subclinical Cushing's syndrome involving the same adrenal gland.

Morita N, Hosaka T, Yamazaki Y, Takahashi K, Sasano H, Ishida H.

J Int Med Res. 2019 Jul;47(7):3360-3370. doi: 10.1177/0300060519855179. Epub 2019 Jul 1. No abstract available.

19.

Extracellular RNAs as Biomarkers of Sporadic Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases.

Hosaka T, Yamashita T, Tamaoka A, Kwak S.

Int J Mol Sci. 2019 Jun 27;20(13). pii: E3148. doi: 10.3390/ijms20133148. Review.

20.
21.

Role of NS5A-L31/Y93 Double Wild-type in Failure of Glecaprevir/Pibrentasvir Double Therapy in Two Patients with a History of Direct-acting Antiviral Agent Failure: An Ultra-deep Sequencing Analysis.

Sano T, Akuta N, Suzuki F, Kasuya K, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Saitoh S, Kobayashi M, Suzuki Y, Kobayashi M, Arase Y, Ikeda K, Kumada H.

Intern Med. 2019 Sep 15;58(18):2657-2662. doi: 10.2169/internalmedicine.2604-18. Epub 2019 Jun 7.

22.

Potassium Metal as Reliable Reference Electrodes of Nonaqueous Potassium Cells.

Hosaka T, Muratsubaki S, Kubota K, Onuma H, Komaba S.

J Phys Chem Lett. 2019 Jun 20;10(12):3296-3300. doi: 10.1021/acs.jpclett.9b00711. Epub 2019 Jun 4.

PMID:
31042388
23.
24.

Initial- and re-treatment effectiveness of glecaprevir and pibrentasvir for Japanese patients with chronic hepatitis C virus-genotype 1/2/3 infections.

Sezaki H, Suzuki F, Hosaka T, Fujiyama S, Kawamura Y, Akuta N, Kobayashi M, Suzuki Y, Saitoh S, Arase Y, Ikeda K, Kobayashi M, Kumada H.

J Gastroenterol. 2019 Oct;54(10):916-927. doi: 10.1007/s00535-019-01575-9. Epub 2019 Mar 22.

PMID:
30903385
25.
26.

The Lack of Hepatocyte Steatosis in Adult-onset Type II Citrullinemia Patients as Assessed by 7-year Interval Paired Biopsies.

Suzuki H, Kawamura Y, Kinowaki K, Akuta N, Kasuya K, Fujiyama S, Sezaki H, Hosaka T, Saitoh S, Kobayashi M, Kobayashi M, Arase Y, Ikeda K, Suzuki F, Suzuki Y, Kumada H.

Intern Med. 2019 Jul 1;58(13):1891-1895. doi: 10.2169/internalmedicine.2374-18. Epub 2019 Feb 25.

27.

Serum lactate levels are associated with serum alanine aminotransferase and total bilirubin levels in patients with type 2 diabetes mellitus: A cross-sectional study.

Ishitobi M, Hosaka T, Morita N, Kondo K, Murashima T, Kitahara A, Takahashi K, Sumitani Y, Tanaka T, Yokoyama T, Kondo T, Ishida H.

Diabetes Res Clin Pract. 2019 Mar;149:1-8. doi: 10.1016/j.diabres.2019.01.028. Epub 2019 Jan 31.

28.

Impact of hepatitis B core-related antigen on the incidence of hepatocellular carcinoma in patients treated with nucleos(t)ide analogues.

Hosaka T, Suzuki F, Kobayashi M, Fujiyama S, Kawamura Y, Sezaki H, Akuta N, Suzuki Y, Saitoh S, Arase Y, Ikeda K, Kobayashi M, Kumada H.

Aliment Pharmacol Ther. 2019 Feb;49(4):457-471. doi: 10.1111/apt.15108. Epub 2019 Jan 20. Erratum in: Aliment Pharmacol Ther. 2019 Jul;50(2):234-235.

PMID:
30663078
29.

High preoperative plasma vasohibin-1 concentration predicts better prognosis in patients with non-small cell lung carcinoma.

Watanabe T, Hosaka T, Ohmori-Matsuda K, Suzuki Y, Suzuki H, Yabuki H, Matsuda Y, Noda M, Sakurada A, Okada Y, Sato Y.

Health Sci Rep. 2018 May 17;1(6):e40. doi: 10.1002/hsr2.40. eCollection 2018 Jun.

30.

Impact of sodium glucose cotransporter 2 inhibitor on histological features and glucose metabolism of non-alcoholic fatty liver disease complicated by diabetes mellitus.

Akuta N, Kawamura Y, Watanabe C, Nishimura A, Okubo M, Mori Y, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 May;49(5):531-539. doi: 10.1111/hepr.13304. Epub 2019 Feb 6.

PMID:
30577089
31.

Primary liver carcinoma with sarcomatous changes: Analysis of 10 cases.

Ohya K, Saitoh S, Fujiyama S, Kawamura Y, Sezaki H, Hosaka T, Akuta N, Kobayashi M, Kobayashi M, Suzuki F, Suzuki Y, Arase Y, Ikeda K, Kinowaki K, Fujii T, Kondo F, Kumada H.

Hepatol Res. 2019 Jun;49(6):711-717. doi: 10.1111/hepr.13295. Epub 2019 Jan 8.

PMID:
30537443
32.

Effectiveness of Particle Radiotherapy in Various Stages of Hepatocellular Carcinoma: A Pilot Study.

Sorin Y, Ikeda K, Kawamura Y, Fujiyama S, Kobayashi M, Hosaka T, Sezaki H, Akuta N, Saitoh S, Suzuki F, Suzuki Y, Arase Y, Kumada H.

Liver Cancer. 2018 Oct;7(4):323-334. doi: 10.1159/000487311. Epub 2018 Mar 14.

33.

ADAR2-dependent A-to-I RNA editing in the extracellular linear and circular RNAs.

Hosaka T, Yamashita T, Teramoto S, Hirose N, Tamaoka A, Kwak S.

Neurosci Res. 2019 Oct;147:48-57. doi: 10.1016/j.neures.2018.11.005. Epub 2018 Nov 16.

PMID:
30448461
34.

Hepatocellular carcinoma is the most common liver-related complication in patients with histopathologically-confirmed NAFLD in Japan.

Akuta N, Kawamura Y, Arase Y, Saitoh S, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Suzuki Y, Suzuki F, Ikeda K, Kumada H.

BMC Gastroenterol. 2018 Nov 6;18(1):165. doi: 10.1186/s12876-018-0900-1.

35.

Complex Association of Virus- and Host-Related Factors with Hepatocellular Carcinoma Rate following Hepatitis C Virus Clearance.

Akuta N, Suzuki F, Sezaki H, Kobayashi M, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H.

J Clin Microbiol. 2019 Jan 2;57(1). pii: e01463-18. doi: 10.1128/JCM.01463-18. Print 2019 Jan.

36.

Polyanionic Compounds for Potassium-Ion Batteries.

Hosaka T, Shimamura T, Kubota K, Komaba S.

Chem Rec. 2018 Oct 30. doi: 10.1002/tcr.201800143. [Epub ahead of print] Review.

PMID:
30378257
37.

Factors Associated With Rates of HBsAg Seroclearance in Adults With Chronic HBV Infection: A Systematic Review and Meta-analysis.

Yeo YH, Ho HJ, Yang HI, Tseng TC, Hosaka T, Trinh HN, Kwak MS, Park YM, Fung JYY, Buti M, Rodríguez M, Treeprasertsuk S, Preda CM, Ungtrakul T, Charatcharoenwitthaya P, Li X, Li J, Zhang J, Le MH, Wei B, Zou B, Le A, Jeong D, Chien N, Kam L, Lee CC, Riveiro-Barciela M, Istratescu D, Sriprayoon T, Chong Y, Tanwandee T, Kobayashi M, Suzuki F, Yuen MF, Lee HS, Kao JH, Lok AS, Wu CY, Nguyen MH.

Gastroenterology. 2019 Feb;156(3):635-646.e9. doi: 10.1053/j.gastro.2018.10.027. Epub 2018 Oct 17.

PMID:
30342034
38.

The self-disproportionation of enantiomers (SDE) of α-amino acid derivatives: facets of steric and electronic properties.

Hosaka T, Imai T, Wzorek A, Marcinkowska M, Kolbus A, Kitagawa O, Soloshonok VA, Klika KD.

Amino Acids. 2019 Feb;51(2):283-294. doi: 10.1007/s00726-018-2664-x. Epub 2018 Oct 11.

PMID:
30311082
39.

Isolation and structure determination of a new cytotoxic peptide, curacozole, from Streptomyces curacoi based on genome mining.

Kaweewan I, Komaki H, Hemmi H, Hoshino K, Hosaka T, Isokawa G, Oyoshi T, Kodani S.

J Antibiot (Tokyo). 2019 Jan;72(1):1-7. doi: 10.1038/s41429-018-0105-4. Epub 2018 Oct 11.

PMID:
30310179
40.

No-touch ablation in hepatocellular carcinoma has the potential to prevent intrasubsegmental recurrence to the same degree as surgical resection.

Kawamura Y, Ikeda K, Shindoh J, Kobayashi Y, Kasuya K, Fujiyama S, Hosaka T, Kobayashi M, Saitoh S, Sezaki H, Akuta N, Suzuki F, Suzuki Y, Arase Y, Hashimoto M, Kumada H.

Hepatol Res. 2019 Feb;49(2):164-176. doi: 10.1111/hepr.13254. Epub 2018 Nov 6.

PMID:
30277295
41.

Long-term outcome of entecavir treatment of nucleos(t)ide analogue-naïve chronic hepatitis B patients in Japan.

Suzuki F, Hosaka T, Suzuki Y, Sezaki H, Akuta N, Fujiyama S, Kawamura Y, Kobayashi M, Saitoh S, Arase Y, Ikeda K, Kobayashi M, Mineta R, Suzuki Y, Kumada H.

J Gastroenterol. 2019 Feb;54(2):182-193. doi: 10.1007/s00535-018-1502-y. Epub 2018 Aug 22.

PMID:
30136216
42.

Efficacy and safety of elbasvir plus grazoprevir combination therapy in Japanese patients infected with hepatitis C virus genotype 1b.

Takeuchi Y, Akuta N, Sezaki H, Suzuki F, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H.

Hepatol Res. 2019 Mar;49(3):256-263. doi: 10.1111/hepr.13242. Epub 2018 Sep 23.

PMID:
30125438
43.

Favorable efficacy of glecaprevir plus pibrentasvir as salvage therapy for HCV failures to prior direct-acting antivirals regimens.

Akuta N, Sezaki H, Suzuki F, Fujiyama S, Kawamura Y, Hosaka T, Kobayashi M, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H.

J Med Virol. 2019 Jan;91(1):102-106. doi: 10.1002/jmv.25278. Epub 2018 Sep 3.

PMID:
30091810
44.

Highly concentrated electrolyte solutions for 4 V class potassium-ion batteries.

Hosaka T, Kubota K, Kojima H, Komaba S.

Chem Commun (Camb). 2018 Jul 24;54(60):8387-8390. doi: 10.1039/c8cc04433c.

PMID:
29998275
45.

Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.

Yoshimaru S, Shizu R, Tsuruta S, Amaike Y, Kano M, Hosaka T, Sasaki T, Yoshinari K.

J Toxicol Sci. 2018;43(7):443-450. doi: 10.2131/jts.43.443.

46.

Circulating microRNA-122 levels are important predictor of hepatitis B virus surface antigen seroclearance.

Akuta N, Suzuki F, Kobayashi M, Hosaka T, Fujiyama S, Kawamura Y, Sezaki H, Kobayashi M, Saitoh S, Suzuki Y, Arase Y, Ikeda K, Kumada H.

J Med Virol. 2018 Oct;90(10):1586-1592. doi: 10.1002/jmv.25238. Epub 2018 Jul 10.

PMID:
29896794
47.

Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes.

Abe T, Amaike Y, Shizu R, Takahashi M, Kano M, Hosaka T, Sasaki T, Kodama S, Matsuzawa A, Yoshinari K.

Toxicol Sci. 2018 Oct 1;165(2):408-419. doi: 10.1093/toxsci/kfy149.

PMID:
29893953
48.

Combined Drug Resistance Mutations Substantially Enhance Enzyme Production in Paenibacillus agaridevorans.

Funane K, Tanaka Y, Hosaka T, Murakami K, Miyazaki T, Shiwa Y, Gibu S, Inaoka T, Kasahara K, Fujita N, Yoshikawa H, Hiraga Y, Ochi K.

J Bacteriol. 2018 Aug 10;200(17). pii: e00188-18. doi: 10.1128/JB.00188-18. Print 2018 Sep 1.

49.

Characterization of CYP2C Induction in Cryopreserved Human Hepatocytes and Its Application in the Prediction of the Clinical Consequences of the Induction.

Nagai M, Hosaka T, Satsukawa M, Yoshinari K.

J Pharm Sci. 2018 Sep;107(9):2479-2488. doi: 10.1016/j.xphs.2018.05.008. Epub 2018 May 23.

PMID:
29802934
50.

Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK.

Morita N, Hosaka T, Kitahara A, Murashima T, Onuma H, Sumitani Y, Takahashi K, Tanaka T, Kondo T, Ishida H.

J Diabetes Res. 2018 Mar 11;2018:9256482. doi: 10.1155/2018/9256482. eCollection 2018.

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