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Items: 7

1.

Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations.

Khiste SK, Liu Z, Roy KR, Uddin MB, Hosain SB, Gu X, Nazzal S, Hill RA, Liu YY.

Mol Cancer Ther. 2020 Feb;19(2):564-574. doi: 10.1158/1535-7163.MCT-19-0366. Epub 2019 Oct 23.

PMID:
31645443
2.

An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells.

Uddin MB, Roy KR, Hosain SB, Khiste SK, Hill RA, Jois SD, Zhao Y, Tackett AJ, Liu YY.

Biochem Pharmacol. 2019 Feb;160:134-145. doi: 10.1016/j.bcp.2018.12.014. Epub 2018 Dec 19.

3.

Incorporation of Fluorescence Ceramide-Based HPLC Assay for Rapidly and Efficiently Assessing Glucosylceramide Synthase In Vivo.

Khiste SK, Hosain SB, Dong Y, Uddin MB, Roy KR, Hill RA, Liu Z, Liu YY.

Sci Rep. 2017 Jun 7;7(1):2976. doi: 10.1038/s41598-017-03320-9.

4.

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.

Hosain SB, Khiste SK, Uddin MB, Vorubindi V, Ingram C, Zhang S, Hill RA, Gu X, Liu YY.

Oncotarget. 2016 Sep 13;7(37):60575-60592. doi: 10.18632/oncotarget.11169.

5.

Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.

Patwardhan GA, Hosain SB, Liu DX, Khiste SK, Zhao Y, Bielawski J, Jazwinski SM, Liu YY.

Biochim Biophys Acta. 2014 Nov;1841(11):1571-80. doi: 10.1016/j.bbalip.2014.08.017. Epub 2014 Sep 6.

6.

Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells.

Gupta V, Bhinge KN, Hosain SB, Xiong K, Gu X, Shi R, Ho MY, Khoo KH, Li SC, Li YT, Ambudkar SV, Jazwinski SM, Liu YY.

J Biol Chem. 2012 Oct 26;287(44):37195-205. doi: 10.1074/jbc.M112.396390. Epub 2012 Aug 30.

7.

The opposite effects of doxorubicin on bone marrow stem cells versus breast cancer stem cells depend on glucosylceramide synthase.

Bhinge KN, Gupta V, Hosain SB, Satyanarayanajois SD, Meyer SA, Blaylock B, Zhang QJ, Liu YY.

Int J Biochem Cell Biol. 2012 Nov;44(11):1770-8. doi: 10.1016/j.biocel.2012.06.010. Epub 2012 Jun 19.

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