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Items: 34


A predicted Francisella tularensis DXD-motif glycosyltransferase blocks immune activation.

Nau GJ, Horzempa J, O'Dee D, Brown MJ, Russo BC, Hernandez A, Dillon ST, Cheng J, Kane LP, Sanker S, Hukriede NA.

Virulence. 2019 Dec;10(1):643-656. doi: 10.1080/21505594.2019.1631662.


Blowing epithelial cell bubbles with GumB: ShlA-family pore-forming toxins induce blebbing and rapid cellular death in corneal epithelial cells.

Brothers KM, Callaghan JD, Stella NA, Bachinsky JM, AlHigaylan M, Lehner KL, Franks JM, Lathrop KL, Collins E, Schmitt DM, Horzempa J, Shanks RMQ.

PLoS Pathog. 2019 Jun 20;15(6):e1007825. doi: 10.1371/journal.ppat.1007825. eCollection 2019 Jun.


Factors associated with the prevalence of neonatal abstinence syndrome in West Virginia.

Rogerson T, Houston A 2nd, Lyman G, Ogden J, Paschall K, Penaranda M, Rios A, Wetzel R, Horzempa J.

J Opioid Manag. 2018 Nov/Dec;14(6):445-452. doi: 10.5055/jom.2018.0477.


The Role and Mechanism of Erythrocyte Invasion by Francisella tularensis.

Schmitt DM, Barnes R, Rogerson T, Haught A, Mazzella LK, Ford M, Gilson T, Birch JW, Sjöstedt A, Reed DS, Franks JM, Stolz DB, Denvir J, Fan J, Rekulapally S, Primerano DA, Horzempa J.

Front Cell Infect Microbiol. 2017 May 9;7:173. doi: 10.3389/fcimb.2017.00173. eCollection 2017.


The potential for flower nectar to allow mosquito to mosquito transmission of Francisella tularensis.

Kenney A, Cusick A, Payne J, Gaughenbaugh A, Renshaw A, Wright J, Seeber R, Barnes R, Florjanczyk A, Horzempa J.

PLoS One. 2017 May 9;12(5):e0175157. doi: 10.1371/journal.pone.0175157. eCollection 2017.


An overview of available drugs for management of opioid abuse during pregnancy.

Laslo J, Brunner JM, Burns D, Butler E, Cunningham A, Killpack R, Pyeritz C, Rinard K, Childers J, Horzempa J.

Matern Health Neonatol Perinatol. 2017 Feb 10;3:4. doi: 10.1186/s40748-017-0044-2. eCollection 2017. Review.


The Practical Consideration of Poliovirus as an Oncolytic Virotherapy.

Denniston E, Crewdson H, Rucinsky N, Stegman A, Remenar D, Moio K, Clark B, Higginbotham A, Keffer R, Brammer S, Horzempa J.

Am J Virol. 2016;5(1):1-7. Epub 2016 Mar 3.


The Integration of Technology into Treatment Programs to Aid in the Reduction of Chronic Pain.

Eckard C, Asbury C, Bolduc B, Camerlengo C, Gotthardt J, Healy L, Waialae L, Zeigler C, Childers J, Horzempa J.

J Pain Manag Med. 2016;2(3). pii: 118. Epub 2016 Dec 31.


The orange spotted cockroach (Blaptica dubia, Serville 1839) is a permissive experimental host for Francisella tularensis.

Eklund BE, Mahdi O, Huntley JF, Collins E, Martin C, Horzempa J, Fisher NA.

Proc W Va Acad Sci. 2017;89(3):34-47. Epub 2017 Dec 4.


Alarm Odor Compounds of the Brown Marmorated Stink Bug Exhibit Antibacterial Activity.

Sagun S, Collins E, Martin C, Nolan EJ, Horzempa J.

J Pharmacogn Nat Prod. 2016 Aug;2(3). pii: 119. Epub 2016 Jul 4.


Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo.

Schmitt DM, Connolly KL, Jerse AE, Detrick MS, Horzempa J.

Int J Antimicrob Agents. 2016 Oct;48(4):367-72. doi: 10.1016/j.ijantimicag.2016.06.009. Epub 2016 Jul 19.


Temperature-Dependent Gentamicin Resistance of Francisella tularensis is Mediated by Uptake Modulation.

Loughman K, Hall J, Knowlton S, Sindeldecker D, Gilson T, Schmitt DM, Birch JW, Gajtka T, Kobe BN, Florjanczyk A, Ingram J, Bakshi CS, Horzempa J.

Front Microbiol. 2016 Jan 28;7:37. doi: 10.3389/fmicb.2016.00037. eCollection 2016.


An Evaluation of Naloxone Use for Opioid Overdoses in West Virginia: A Literature Review.

Beheshti A, Lucas L, Dunz T, Haydash M, Chiodi H, Edmiston B, Ford C, Bohn N, Stein JH, Berrett A, Sobota B, Horzempa J.

Am Med J. 2015 Jul 9;6(1):9-13.


Considerations for a Primary Care Physician Assistant in Treating Kidney Transplant Recipients.

Aston R, Durkin A, Harris K, Mace A, Moore S, Smith B, Soult E, Wright M, Yothers D, Latos DL, Horzempa J.

Qual Prim Care. 2015;23(1):39-45.


Genetic engineering of Francisella tularensis LVS for use as a novel live vaccine platform against Pseudomonas aeruginosa infections.

Robinson CM, Kobe BN, Schmitt DM, Phair B, Gilson T, Jung JY, Roberts L, Liao J, Camerlengo C, Chang B, Davis M, Figurski L, Sindeldecker D, Horzempa J.

Bioengineered. 2015;6(2):82-8. doi: 10.1080/21655979.2015.1011033.


Adequate Vitamin D3 Supplementation During Pregnancy: Decreasing the Prevalence of Asthma and Food Allergies.

Finkel J, Cira C, Mazzella L, Bartyzel J, Ramanna A, Strimel K, Waturuocha A, Musser N, Burress J, Brammer S, Wetzel R, Horzempa J.

Matern Pediatr Nutr. 2015;2(1). pii: 105. Epub 2015 Dec 28.


The use of resazurin as a novel antimicrobial agent against Francisella tularensis.

Schmitt DM, O'Dee DM, Cowan BN, Birch JW, Mazzella LK, Nau GJ, Horzempa J.

Front Cell Infect Microbiol. 2013 Dec 6;3:93. doi: 10.3389/fcimb.2013.00093. eCollection 2013.


Neonatal macrophages express elevated levels of interleukin-27 that oppose immune responses.

Kraft JD, Horzempa J, Davis C, Jung JY, Peña MM, Robinson CM.

Immunology. 2013 Aug;139(4):484-93. doi: 10.1111/imm.12095.


Role of NK cells in host defense against pulmonary type A Francisella tularensis infection.

Schmitt DM, O'Dee DM, Brown MJ, Horzempa J, Russo BC, Morel PA, Nau GJ.

Microbes Infect. 2013 Mar;15(3):201-11. doi: 10.1016/j.micinf.2012.11.008. Epub 2012 Dec 1.


A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy.

Schmitt DM, O'Dee DM, Horzempa J, Carlson PE Jr, Russo BC, Bales JM, Brown MJ, Nau GJ.

PLoS One. 2012;7(2):e31172. doi: 10.1371/journal.pone.0031172. Epub 2012 Feb 15.


A Francisella tularensis locus required for spermine responsiveness is necessary for virulence.

Russo BC, Horzempa J, O'Dee DM, Schmitt DM, Brown MJ, Carlson PE Jr, Xavier RJ, Nau GJ.

Infect Immun. 2011 Sep;79(9):3665-76. doi: 10.1128/IAI.00135-11. Epub 2011 Jun 13.


Invasion of erythrocytes by Francisella tularensis.

Horzempa J, O'Dee DM, Stolz DB, Franks JM, Clay D, Nau GJ.

J Infect Dis. 2011 Jul 1;204(1):51-9. doi: 10.1093/infdis/jir221.


New vector tools with a hygromycin resistance marker for use with opportunistic pathogens.

Kalivoda EJ, Horzempa J, Stella NA, Sadaf A, Kowalski RP, Nau GJ, Shanks RM.

Mol Biotechnol. 2011 May;48(1):7-14. doi: 10.1007/s12033-010-9342-x.


Glycosylation of pilin and nonpilin protein constructs by Pseudomonas aeruginosa 1244.

Qutyan M, Henkel M, Horzempa J, Quinn M, Castric P.

J Bacteriol. 2010 Nov;192(22):5972-81. doi: 10.1128/JB.00007-10. Epub 2010 Sep 10.


Francisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo.

Horzempa J, O'Dee DM, Shanks RM, Nau GJ.

Infect Immun. 2010 Jun;78(6):2607-19. doi: 10.1128/IAI.00134-10. Epub 2010 Apr 12.


Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis.

Horzempa J, Shanks RM, Brown MJ, Russo BC, O'Dee DM, Nau GJ.

J Microbiol Methods. 2010 Jan;80(1):106-8. doi: 10.1016/j.mimet.2009.10.013. Epub 2009 Oct 29.


Global transcriptional response to spermine, a component of the intramacrophage environment, reveals regulation of Francisella gene expression through insertion sequence elements.

Carlson PE Jr, Horzempa J, O'Dee DM, Robinson CM, Neophytou P, Labrinidis A, Nau GJ.

J Bacteriol. 2009 Nov;191(22):6855-64. doi: 10.1128/JB.00995-09. Epub 2009 Sep 11.


Global transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis.

Horzempa J, Carlson PE Jr, O'Dee DM, Shanks RM, Nau GJ.

BMC Microbiol. 2008 Oct 8;8:172. doi: 10.1186/1471-2180-8-172.


Immunization with a Pseudomonas aeruginosa 1244 pilin provides O-antigen-specific protection.

Horzempa J, Held TK, Cross AS, Furst D, Qutyan M, Neely AN, Castric P.

Clin Vaccine Immunol. 2008 Apr;15(4):590-7. doi: 10.1128/CVI.00476-07. Epub 2008 Feb 13.


Characterization and application of a glucose-repressible promoter in Francisella tularensis.

Horzempa J, Tarwacki DM, Carlson PE Jr, Robinson CM, Nau GJ.

Appl Environ Microbiol. 2008 Apr;74(7):2161-70. doi: 10.1128/AEM.02360-07. Epub 2008 Feb 1.


Pseudomonas aeruginosa 1244 pilin glycosylation: glycan substrate recognition.

Horzempa J, Dean CR, Goldberg JB, Castric P.

J Bacteriol. 2006 Jun;188(12):4244-52.


Influence of pilin glycosylation on Pseudomonas aeruginosa 1244 pilus function.

Smedley JG 3rd, Jewell E, Roguskie J, Horzempa J, Syboldt A, Stolz DB, Castric P.

Infect Immun. 2005 Dec;73(12):7922-31.


Glycosylation substrate specificity of Pseudomonas aeruginosa 1244 pilin.

Horzempa J, Comer JE, Davis SA, Castric P.

J Biol Chem. 2006 Jan 13;281(2):1128-36. Epub 2005 Nov 11.

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