Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 228

1.

Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes.

Spanier JA, Tse HM, Horwitz MS, Fife BT.

Front Endocrinol (Lausanne). 2019 May 16;10:315. doi: 10.3389/fendo.2019.00315. eCollection 2019. No abstract available.

2.

Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.

Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL.

Cell. 2019 Apr 4;177(2):492-493. doi: 10.1016/j.cell.2019.03.037. No abstract available.

PMID:
30951673
3.

Virus envelope tissue factor promotes infection in mice.

Sutherland MR, Simon AY, Shanina I, Horwitz MS, Ruf W, Pryzdial ELG.

J Thromb Haemost. 2019 Mar;17(3):482-491. doi: 10.1111/jth.14389. Epub 2019 Feb 20.

PMID:
30659719
4.

Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.

Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL.

Cell. 2019 Jan 24;176(3):610-624.e18. doi: 10.1016/j.cell.2018.11.035. Epub 2019 Jan 3. Erratum in: Cell. 2019 Apr 4;177(2):492-493.

PMID:
30612739
5.

Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations.

Hart MR, Anderson DJ, Porter CC, Neff T, Levin M, Horwitz MS.

PLoS Genet. 2018 Sep 14;14(9):e1007642. doi: 10.1371/journal.pgen.1007642. eCollection 2018 Sep.

6.

Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice.

Lee JTC, Shanina I, Chu YN, Horwitz MS, Johnson JD.

Sci Rep. 2018 Mar 15;8(1):4588. doi: 10.1038/s41598-018-23026-w.

7.

Acute lymphoblastic leukemia in a child with Leri-Weill syndrome and complete SHOX gene deletion: A Case Report.

Volejnikova J, Zapletalova J, Jarosova M, Urbankova H, Petr V, Klaskova E, Horwitz MS, Hajduch M, Mihal V.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Mar;162(1):65-70. doi: 10.5507/bp.2018.002. Epub 2018 Feb 21.

8.

Generation of a Dual-Target, Safe, Inexpensive Microbicide that Protects Against HIV-1 and HSV-2 Disease.

Farr Zuend C, Nomellini JF, Smit J, Horwitz MS.

Sci Rep. 2018 Feb 12;8(1):2786. doi: 10.1038/s41598-018-21134-1.

9.

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.

Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH.

Sci Rep. 2018 Jan 8;8(1):33. doi: 10.1038/s41598-017-18495-4.

10.

Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset.

Morse ZJ, Horwitz MS.

Front Endocrinol (Lausanne). 2017 Sep 26;8:249. doi: 10.3389/fendo.2017.00249. eCollection 2017. Review.

11.

Fresh Ideas, Foundational Experiments (FIFE): Immunology and Diabetes 2016 FIFE Symposium.

Mouat IC, Morse ZJ, Jean-Baptiste VSE, Allanach JR, Horwitz MS.

Front Endocrinol (Lausanne). 2017 Sep 19;8:238. doi: 10.3389/fendo.2017.00238. eCollection 2017.

12.

Landscape review of current HIV 'kick and kill' cure research - some kicking, not enough killing.

Thorlund K, Horwitz MS, Fife BT, Lester R, Cameron DW.

BMC Infect Dis. 2017 Aug 29;17(1):595. doi: 10.1186/s12879-017-2683-3. Review.

13.

Type 1 Diabetes and Type 1 Interferonopathies: Localization of a Type 1 Common Thread of Virus Infection in the Pancreas.

Jean-Baptiste VSE, Xia CQ, Clare-Salzler MJ, Horwitz MS.

EBioMedicine. 2017 Aug;22:10-17. doi: 10.1016/j.ebiom.2017.06.014. Epub 2017 Jun 21. Review.

14.

GATA2 deficiency and related myeloid neoplasms.

Wlodarski MW, Collin M, Horwitz MS.

Semin Hematol. 2017 Apr;54(2):81-86. doi: 10.1053/j.seminhematol.2017.05.002. Epub 2017 May 10.

15.

Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.

Guarino C, Hamon Y, Croix C, Lamort AS, Dallet-Choisy S, Marchand-Adam S, Lesner A, Baranek T, Viaud-Massuard MC, Lauritzen C, Pedersen J, Heuzé-Vourc'h N, Si-Tahar M, Fıratlı E, Jenne DE, Gauthier F, Horwitz MS, Borregaard N, Korkmaz B.

Biochem Pharmacol. 2017 May 1;131:52-67. doi: 10.1016/j.bcp.2017.02.009. Epub 2017 Feb 11.

PMID:
28193451
16.

GATA factor mutations in hematologic disease.

Crispino JD, Horwitz MS.

Blood. 2017 Apr 13;129(15):2103-2110. doi: 10.1182/blood-2016-09-687889. Epub 2017 Feb 8. Review.

17.

Genome sequencing in a case of Niemann-Pick type C.

Dougherty M, Lazar J, Klein JC, Diaz K, Gobillot T, Grunblatt E, Hasle N, Lawrence D, Maurano M, Nelson M, Olson G, Srivatsan S, Shendure J, Keene CD, Bird T, Horwitz MS, Marshall DA.

Cold Spring Harb Mol Case Stud. 2016 Nov;2(6):a001222.

18.

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J.

Science. 2016 Jul 29;353(6298):aaf7907. doi: 10.1126/science.aaf7907. Epub 2016 May 26.

19.

miR, miR in the Cell, Does the Virus Control Them All?

Richardson SJ, Horwitz MS.

Diabetes. 2016 Apr;65(4):823-5. doi: 10.2337/dbi15-0039. No abstract available.

20.

Erratum: Heritable GATA2 mutations associated with familial AML-MDS: a case report and review of literature.

Gao J, Gentzler RD, Timms AE, Horwitz MS, Frankfurt O, Altman JK, Peterson LC.

J Hematol Oncol. 2015 Dec 29;8:131. doi: 10.1186/s13045-015-0228-z. No abstract available.

21.

Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy.

Wang D, Shanina I, Toyofuku WM, Horwitz MS, Scott MD.

PLoS One. 2015 Dec 16;10(12):e0145179. doi: 10.1371/journal.pone.0145179. eCollection 2015.

22.

The Role of Latently Infected B Cells in CNS Autoimmunity.

Márquez AC, Horwitz MS.

Front Immunol. 2015 Oct 28;6:544. doi: 10.3389/fimmu.2015.00544. eCollection 2015. Review.

23.

Latent virus infection upregulates CD40 expression facilitating enhanced autoimmunity in a model of multiple sclerosis.

Casiraghi C, Márquez AC, Shanina I, Horwitz MS.

Sci Rep. 2015 Sep 10;5:13995. doi: 10.1038/srep13995.

24.

Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells.

Nayak RC, Trump LR, Aronow BJ, Myers K, Mehta P, Kalfa T, Wellendorf AM, Valencia CA, Paddison PJ, Horwitz MS, Grimes HL, Lutzko C, Cancelas JA.

J Clin Invest. 2015 Aug 3;125(8):3103-16. doi: 10.1172/JCI80924. Epub 2015 Jul 20.

25.

Mechanisms and clinical applications of chromosomal instability in lymphoid malignancy.

Krem MM, Press OW, Horwitz MS, Tidwell T.

Br J Haematol. 2015 Oct;171(1):13-28. doi: 10.1111/bjh.13507. Epub 2015 May 26. Review.

PMID:
26018193
26.

Characterisation of a compound in-cis GATA2 germline mutation in a pedigree presenting with myelodysplastic syndrome/acute myeloid leukemia with concurrent thrombocytopenia.

Hahn CN, Brautigan PJ, Chong CE, Janssan A, Venugopal P, Lee Y, Tims AE, Horwitz MS, Klingler-Hoffmann M, Scott HS.

Leukemia. 2015 Aug;29(8):1795-7. doi: 10.1038/leu.2015.40. Epub 2015 Feb 13. No abstract available.

PMID:
25676417
27.

Reduced expression of the MDA5 Gene IFIH1 prevents autoimmune diabetes.

Lincez PJ, Shanina I, Horwitz MS.

Diabetes. 2015 Jun;64(6):2184-93. doi: 10.2337/db14-1223. Epub 2015 Jan 15.

28.

Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy.

Zhang MY, Churpek JE, Keel SB, Walsh T, Lee MK, Loeb KR, Gulsuner S, Pritchard CC, Sanchez-Bonilla M, Delrow JJ, Basom RS, Forouhar M, Gyurkocza B, Schwartz BS, Neistadt B, Marquez R, Mariani CJ, Coats SA, Hofmann I, Lindsley RC, Williams DA, Abkowitz JL, Horwitz MS, King MC, Godley LA, Shimamura A.

Nat Genet. 2015 Feb;47(2):180-5. doi: 10.1038/ng.3177. Epub 2015 Jan 12.

29.

Genome sequencing of idiopathic pulmonary fibrosis in conjunction with a medical school human anatomy course.

Kumar A, Dougherty M, Findlay GM, Geisheker M, Klein J, Lazar J, Machkovech H, Resnick J, Resnick R, Salter AI, Talebi-Liasi F, Arakawa C, Baudin J, Bogaard A, Salesky R, Zhou Q, Smith K, Clark JI, Shendure J, Horwitz MS.

PLoS One. 2014 Sep 5;9(9):e106744. doi: 10.1371/journal.pone.0106744. eCollection 2014.

30.

Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects.

Connelly JP, Kwon EM, Gao Y, Trivedi NS, Elkahloun AG, Horwitz MS, Cheng L, Liu PP.

Blood. 2014 Sep 18;124(12):1926-30.

31.

Is type 1 diabetes "going viral"?

Richardson SJ, Horwitz MS.

Diabetes. 2014 Jul;63(7):2203-5. doi: 10.2337/db14-0510. No abstract available.

32.

Heritable GATA2 mutations associated with familial AML-MDS: a case report and review of literature.

Gao J, Gentzler RD, Timms AE, Horwitz MS, Frankfurt O, Altman JK, Peterson LC.

J Hematol Oncol. 2014 Apr 22;7:36. doi: 10.1186/1756-8722-7-36. Review. Erratum in: J Hematol Oncol. 2015;8:131.

33.

GATA2 deficiency: flesh and blood.

Horwitz MS.

Blood. 2014 Feb 6;123(6):799-800. doi: 10.1182/blood-2013-12-539858. No abstract available.

34.

Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms.

Tidwell T, Wechsler J, Nayak RC, Trump L, Salipante SJ, Cheng JC, Donadieu J, Glaubach T, Corey SJ, Grimes HL, Lutzko C, Cancelas JA, Horwitz MS.

Blood. 2014 Jan 23;123(4):562-9. doi: 10.1182/blood-2013-07-513242. Epub 2013 Nov 1.

35.

Clonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis.

Salk JJ, Bansal A, Lai LA, Crispin DA, Ussakli CH, Horwitz MS, Bronner MP, Brentnall TA, Loeb LA, Rabinovitch PS, Risques RA.

Inflamm Bowel Dis. 2013 Nov;19(12):2593-602. doi: 10.1097/MIB.0b013e3182a87640.

36.

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.

Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C, Wechsler J, Yang J, Hayes J, Klein RJ, Zhang J, Wei L, Wu G, Rusch M, Nagahawatte P, Ma J, Chen SC, Song G, Cheng J, Meyers P, Bhojwani D, Jhanwar S, Maslak P, Fleisher M, Littman J, Offit L, Rau-Murthy R, Fleischut MH, Corines M, Murali R, Gao X, Manschreck C, Kitzing T, Murty VV, Raimondi S, Kuiper RP, Simons A, Schiffman JD, Onel K, Plon SE, Wheeler D, Ritter D, Ziegler DS, Tucker K, Sutton R, Chenevix-Trench G, Li J, Huntsman DG, Hansford S, Senz J, Walsh T, Lee M, Hahn CN, Roberts K, King MC, Lo SM, Levine RL, Viale A, Socci ND, Nathanson KL, Scott HS, Daly M, Lipkin SM, Lowe SW, Downing JR, Altshuler D, Sandlund JT, Horwitz MS, Mullighan CG, Offit K.

Nat Genet. 2013 Oct;45(10):1226-1231. doi: 10.1038/ng.2754. Epub 2013 Sep 8.

37.

Development of an HIV-1 Microbicide Based on Caulobacter crescentus: Blocking Infection by High-Density Display of Virus Entry Inhibitors.

Farr C, Nomellini JF, Ailon E, Shanina I, Sangsari S, Cavacini LA, Smit J, Horwitz MS.

PLoS One. 2013 Jun 19;8(6):e65965. doi: 10.1371/journal.pone.0065965. Print 2013.

38.

Mitotic errors, aneuploidy and micronuclei in Hodgkin lymphoma pathogenesis.

Krem MM, Horwitz MS.

Commun Integr Biol. 2013 May 1;6(3):e23544. doi: 10.4161/cib.23544. Epub 2013 May 13.

39.

Support for the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia from exome sequencing in multiplex families.

Timms AE, Dorschner MO, Wechsler J, Choi KY, Kirkwood R, Girirajan S, Baker C, Eichler EE, Korvatska O, Roche KW, Horwitz MS, Tsuang DW.

JAMA Psychiatry. 2013 Jun;70(6):582-90. doi: 10.1001/jamapsychiatry.2013.1195.

PMID:
23553203
40.

ELANE mutations in cyclic and severe congenital neutropenia: genetics and pathophysiology.

Horwitz MS, Corey SJ, Grimes HL, Tidwell T.

Hematol Oncol Clin North Am. 2013 Feb;27(1):19-41, vii. doi: 10.1016/j.hoc.2012.10.004. Epub 2012 Nov 7. Review.

41.

Use of somatic mutations to quantify random contributions to mouse development.

Zhou W, Tan Y, Anderson DJ, Crist EM, Ruohola-Baker H, Salipante SJ, Horwitz MS.

BMC Genomics. 2013 Jan 18;14:39. doi: 10.1186/1471-2164-14-39.

42.

Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice.

Durand CA, Richer MJ, Brenker K, Graves M, Shanina I, Choi K, Horwitz MS, Puri KD, Gold MR.

Autoimmunity. 2013 Feb;46(1):62-73. doi: 10.3109/08916934.2012.732130.

PMID:
23039284
43.

The kelch protein KLHDC8B guards against mitotic errors, centrosomal amplification, and chromosomal instability.

Krem MM, Luo P, Ing BI, Horwitz MS.

J Biol Chem. 2012 Nov 9;287(46):39083-93. doi: 10.1074/jbc.M112.390088. Epub 2012 Sep 17.

44.

Gammaherpesvirus latency accentuates EAE pathogenesis: relevance to Epstein-Barr virus and multiple sclerosis.

Casiraghi C, Shanina I, Cho S, Freeman ML, Blackman MA, Horwitz MS.

PLoS Pathog. 2012;8(5):e1002715. doi: 10.1371/journal.ppat.1002715. Epub 2012 May 17.

45.

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition.

Zhou W, Choi M, Margineantu D, Margaretha L, Hesson J, Cavanaugh C, Blau CA, Horwitz MS, Hockenbery D, Ware C, Ruohola-Baker H.

EMBO J. 2012 May 2;31(9):2103-16. doi: 10.1038/emboj.2012.71. Epub 2012 Mar 23.

46.

Immunomodulation of antigen presenting cells promotes natural regulatory T cells that prevent autoimmune diabetes in NOD mice.

Richer MJ, Lavallée DJ, Shanina I, Horwitz MS.

PLoS One. 2012;7(2):e31153. doi: 10.1371/journal.pone.0031153. Epub 2012 Feb 15.

47.

PSGL-1 regulates the migration and proliferation of CD8(+) T cells under homeostatic conditions.

Veerman KM, Carlow DA, Shanina I, Priatel JJ, Horwitz MS, Ziltener HJ.

J Immunol. 2012 Feb 15;188(4):1638-46. doi: 10.4049/jimmunol.1103026. Epub 2012 Jan 16.

48.

Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature.

Kazenwadel J, Secker GA, Liu YJ, Rosenfeld JA, Wildin RS, Cuellar-Rodriguez J, Hsu AP, Dyack S, Fernandez CV, Chong CE, Babic M, Bardy PG, Shimamura A, Zhang MY, Walsh T, Holland SM, Hickstein DD, Horwitz MS, Hahn CN, Scott HS, Harvey NL.

Blood. 2012 Feb 2;119(5):1283-91. doi: 10.1182/blood-2011-08-374363. Epub 2011 Dec 6.

49.

Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct.

Zhou W, Dosey TL, Biechele T, Moon RT, Horwitz MS, Ruohola-Baker H.

PLoS One. 2011;6(11):e27460. doi: 10.1371/journal.pone.0027460. Epub 2011 Nov 23.

50.

Decoding cell lineage from acquired mutations using arbitrary deep sequencing.

Carlson CA, Kas A, Kirkwood R, Hays LE, Preston BD, Salipante SJ, Horwitz MS.

Nat Methods. 2011 Nov 27;9(1):78-80. doi: 10.1038/nmeth.1781.

Supplemental Content

Loading ...
Support Center