Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 115

1.

A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration.

Lagarrigue F, Vikas Anekal P, Lee HS, Bachir AI, Ablack JN, Horwitz AF, Ginsberg MH.

Nat Commun. 2015 Sep 30;6:8492. doi: 10.1038/ncomms9492.

2.

High glucose-mediated oxidative stress impairs cell migration.

Lamers ML, Almeida ME, Vicente-Manzanares M, Horwitz AF, Santos MF.

PLoS One. 2011;6(8):e22865. doi: 10.1371/journal.pone.0022865. Epub 2011 Aug 3.

3.

Stochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells.

Cirit M, Krajcovic M, Choi CK, Welf ES, Horwitz AF, Haugh JM.

PLoS Comput Biol. 2010 Feb 26;6(2):e1000688. doi: 10.1371/journal.pcbi.1000688.

4.

Tensin1 requires protein phosphatase-1alpha in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion.

Hall EH, Daugherty AE, Choi CK, Horwitz AF, Brautigan DL.

J Biol Chem. 2009 Dec 11;284(50):34713-22. doi: 10.1074/jbc.M109.059592. Epub 2009 Oct 13.

5.

Boron polylactide nanoparticles exhibiting fluorescence and phosphorescence in aqueous medium.

Pfister A, Zhang G, Zareno J, Horwitz AF, Fraser CL.

ACS Nano. 2008 Jun;2(6):1252-8. doi: 10.1021/nn7003525.

6.

Segregation and activation of myosin IIB creates a rear in migrating cells.

Vicente-Manzanares M, Koach MA, Whitmore L, Lamers ML, Horwitz AF.

J Cell Biol. 2008 Nov 3;183(3):543-54. doi: 10.1083/jcb.200806030. Epub 2008 Oct 27.

7.

CaMK-II promotes focal adhesion turnover and cell motility by inducing tyrosine dephosphorylation of FAK and paxillin.

Easley CA 4th, Brown CM, Horwitz AF, Tombes RM.

Cell Motil Cytoskeleton. 2008 Aug;65(8):662-74. doi: 10.1002/cm.20294.

8.

ADAM2 promotes migration of neuroblasts in the rostral migratory stream to the olfactory bulb.

Murase S, Cho C, White JM, Horwitz AF.

Eur J Neurosci. 2008 Apr;27(7):1585-95. doi: 10.1111/j.1460-9568.2008.06119.x.

9.

Mapping the number of molecules and brightness in the laser scanning microscope.

Digman MA, Dalal R, Horwitz AF, Gratton E.

Biophys J. 2008 Mar 15;94(6):2320-32. Epub 2007 Dec 20.

10.

Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase.

Owen KA, Pixley FJ, Thomas KS, Vicente-Manzanares M, Ray BJ, Horwitz AF, Parsons JT, Beggs HE, Stanley ER, Bouton AH.

J Cell Biol. 2007 Dec 17;179(6):1275-87. Epub 2007 Dec 10.

11.

Identification of phosphorylation sites in betaPIX and PAK1.

Mayhew MW, Jeffery ED, Sherman NE, Nelson K, Polefrone JM, Pratt SJ, Shabanowitz J, Parsons JT, Fox JW, Hunt DF, Horwitz AF.

J Cell Sci. 2007 Nov 15;120(Pt 22):3911-8. No abstract available.

12.

Determination of particle number and brightness using a laser scanning confocal microscope operating in the analog mode.

Dalal RB, Digman MA, Horwitz AF, Vetri V, Gratton E.

Microsc Res Tech. 2008 Jan;71(1):69-81.

13.

Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells.

Vicente-Manzanares M, Zareno J, Whitmore L, Choi CK, Horwitz AF.

J Cell Biol. 2007 Feb 26;176(5):573-80. Epub 2007 Feb 20. Erratum in: J Cell Biol. 2007 Mar 26;176(7):1073.

14.

alpha5 integrin signaling regulates the formation of spines and synapses in hippocampal neurons.

Webb DJ, Zhang H, Majumdar D, Horwitz AF.

J Biol Chem. 2007 Mar 9;282(10):6929-35. Epub 2007 Jan 9.

15.

Identification of protein networks associated with the PAK1-betaPIX-GIT1-paxillin signaling complex by mass spectrometry.

Mayhew MW, Webb DJ, Kovalenko M, Whitmore L, Fox JW, Horwitz AF.

J Proteome Res. 2006 Sep;5(9):2417-23.

PMID:
16944954
16.

Mechanism of polarized protrusion formation on neuronal precursors migrating in the developing chicken cerebellum.

Sakakibara A, Horwitz AF.

J Cell Sci. 2006 Sep 1;119(Pt 17):3583-92. Epub 2006 Aug 15.

17.

From imaging to understanding: Frontiers in Live Cell Imaging, Bethesda, MD, April 19-21, 2006.

Wang YL, Hahn KM, Murphy RF, Horwitz AF.

J Cell Biol. 2006 Aug 14;174(4):481-4. Erratum in: J Cell Biol. 2006 Sep 11;174(6):903.

18.

Identification of phosphorylation sites in GIT1.

Webb DJ, Mayhew MW, Kovalenko M, Schroeder MJ, Jeffery ED, Whitmore L, Shabanowitz J, Hunt DF, Horwitz AF.

J Cell Sci. 2006 Jul 15;119(Pt 14):2847-50. No abstract available.

19.

Phosphorylation of serine 709 in GIT1 regulates protrusive activity in cells.

Webb DJ, Kovalenko M, Whitmore L, Horwitz AF.

Biochem Biophys Res Commun. 2006 Aug 11;346(4):1284-8. Epub 2006 Jun 14.

PMID:
16797488
20.

In vivo dynamics of Rac-membrane interactions.

Moissoglu K, Slepchenko BM, Meller N, Horwitz AF, Schwartz MA.

Mol Biol Cell. 2006 Jun;17(6):2770-9. Epub 2006 Apr 5.

21.

Methods for the detection of paxillin post-translational modifications and interacting proteins by mass spectrometry.

Schroeder MJ, Webb DJ, Shabanowitz J, Horwitz AF, Hunt DF.

J Proteome Res. 2005 Sep-Oct;4(5):1832-41.

PMID:
16212439
22.

Migration of perilesional microglia after focal brain injury and modulation by CC chemokine receptor 5: an in situ time-lapse confocal imaging study.

Carbonell WS, Murase S, Horwitz AF, Mandell JW.

J Neurosci. 2005 Jul 27;25(30):7040-7. Erratum in: J Neurosci. 2005 Aug 10;25(32):table of contents.

23.

A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC.

Zhang H, Webb DJ, Asmussen H, Niu S, Horwitz AF.

J Neurosci. 2005 Mar 30;25(13):3379-88.

24.
25.

Cell migration: an overview.

Webb DJ, Zhang H, Horwitz AF.

Methods Mol Biol. 2005;294:3-11. Review.

PMID:
15576900
26.

Spatial mapping of integrin interactions and dynamics during cell migration by image correlation microscopy.

Wiseman PW, Brown CM, Webb DJ, Hebert B, Johnson NL, Squier JA, Ellisman MH, Horwitz AF.

J Cell Sci. 2004 Nov 1;117(Pt 23):5521-34. Epub 2004 Oct 12.

27.

Directions in cell migration along the rostral migratory stream: the pathway for migration in the brain.

Murase S, Horwitz AF.

Curr Top Dev Biol. 2004;61:135-52. Review. No abstract available.

PMID:
15350400
28.

Talin: an emerging focal point of adhesion dynamics.

Nayal A, Webb DJ, Horwitz AF.

Curr Opin Cell Biol. 2004 Feb;16(1):94-8. Review.

PMID:
15037311
29.

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly.

Webb DJ, Donais K, Whitmore LA, Thomas SM, Turner CE, Parsons JT, Horwitz AF.

Nat Cell Biol. 2004 Feb;6(2):154-61. Epub 2004 Jan 25.

PMID:
14743221
30.

Illuminating adhesion complexes in migrating cells: moving toward a bright future.

Webb DJ, Brown CM, Horwitz AF.

Curr Opin Cell Biol. 2003 Oct;15(5):614-20. Review.

PMID:
14519397
31.

New dimensions in cell migration.

Webb DJ, Horwitz AF.

Nat Cell Biol. 2003 Aug;5(8):690-2. No abstract available.

PMID:
12894172
32.

Synapse formation is regulated by the signaling adaptor GIT1.

Zhang H, Webb DJ, Asmussen H, Horwitz AF.

J Cell Biol. 2003 Apr 14;161(1):131-42.

33.

Fluorescence imaging of mobility shifts: an expression cloning method for identification of cell signaling targets.

Mandell JW, Manabe R, Horwitz AF, Baumgart JP.

Lab Invest. 2002 Dec;82(12):1631-6.

PMID:
12480913
34.

Cell migration in slice cultures.

Webb DJ, Asmussen H, Murase S, Horwitz AF.

Methods Cell Biol. 2002;69:341-58. No abstract available.

PMID:
12071004
36.

Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again.

Webb DJ, Parsons JT, Horwitz AF.

Nat Cell Biol. 2002 Apr;4(4):E97-100. Review.

PMID:
11944043
37.

The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL).

West KA, Zhang H, Brown MC, Nikolopoulos SN, Riedy MC, Horwitz AF, Turner CE.

J Cell Biol. 2001 Jul 9;154(1):161-76.

38.
39.

The role of transient ERK2 signals in fibronectin- and insulin-mediated DNA synthesis.

Asthagiri AR, Reinhart CA, Horwitz AF, Lauffenburger DA.

J Cell Sci. 2000 Dec;113 Pt 24:4499-510.

40.
41.

A rapid and sensitive quantitative kinase activity assay using a convenient 96-well format.

Asthagiri AR, Horwitz AF, Lauffenburger DA.

Anal Biochem. 1999 May 1;269(2):342-7.

PMID:
10222008
42.

Kinetic model for integrin-mediated adhesion release during cell migration.

Palecek SP, Horwitz AF, Lauffenburger DA.

Ann Biomed Eng. 1999 Mar-Apr;27(2):219-35.

PMID:
10199699
43.

Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal.

Sastry SK, Lakonishok M, Wu S, Truong TQ, Huttenlocher A, Turner CE, Horwitz AF.

J Cell Biol. 1999 Mar 22;144(6):1295-309.

44.
45.

Immunopurification of a sarcomeric junctional protein complex containing GAPDH.

McDonald KA, Muschler J, Horwitz AF.

Exp Cell Res. 1998 Sep 15;243(2):305-18.

PMID:
9743590
46.

Integrin and cadherin synergy regulates contact inhibition of migration and motile activity.

Huttenlocher A, Lakonishok M, Kinder M, Wu S, Truong T, Knudsen KA, Horwitz AF.

J Cell Biol. 1998 Apr 20;141(2):515-26.

47.

Physical and biochemical regulation of integrin release during rear detachment of migrating cells.

Palecek SP, Huttenlocher A, Horwitz AF, Lauffenburger DA.

J Cell Sci. 1998 Apr;111 ( Pt 7):929-40.

48.

Regulation of cell migration by the calcium-dependent protease calpain.

Huttenlocher A, Palecek SP, Lu Q, Zhang W, Mellgren RL, Lauffenburger DA, Ginsberg MH, Horwitz AF.

J Biol Chem. 1997 Dec 26;272(52):32719-22.

49.

Integrins and health.

Horwitz AF.

Sci Am. 1997 May;276(5):68-75. No abstract available.

PMID:
9109263
50.

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness.

Palecek SP, Loftus JC, Ginsberg MH, Lauffenburger DA, Horwitz AF.

Nature. 1997 Feb 6;385(6616):537-40. Erratum in: Nature 1997 Jul 10;388(6638):210.

PMID:
9020360

Supplemental Content

Loading ...
Support Center