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Items: 1 to 50 of 278

1.

Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer's Disease Pathology.

Stoiljkovic M, Kelley C, Stutz B, Horvath TL, Hajós M.

Cereb Cortex. 2018 Jun 16. doi: 10.1093/cercor/bhy140. [Epub ahead of print]

PMID:
29920597
2.

Viral Vectors for Studying Brain Mechanisms that Control Energy Homeostasis.

Mancini G, Horvath TL.

Cell Metab. 2018 Jun 5;27(6):1168-1175. doi: 10.1016/j.cmet.2018.05.015. Review.

PMID:
29874565
3.

Comparative Analysis of Zearalenone Effects on Thyroid Receptor Alpha (TRα) and Beta (TRβ) Expression in Rat Primary Cerebellar Cell Cultures.

Kiss DS, Ioja E, Toth I, Barany Z, Jocsak G, Bartha T, Horvath TL, Zsarnovszky A.

Int J Mol Sci. 2018 May 11;19(5). pii: E1440. doi: 10.3390/ijms19051440.

4.

Patient-Derived iPSC-Hypothamic Neurons: The Ultimate Protocol.

Miletta MC, Horvath TL.

Cell Stem Cell. 2018 May 3;22(5):615-616. doi: 10.1016/j.stem.2018.04.019.

PMID:
29727675
5.

Myeloid sirtuin1 deficiency aggravates hippocampal inflammation in mice fed high-fat diets.

Kim KE, Jeong EA, Lee JY, Yi CO, Park KA, Jin Z, Lee JE, Horvath TL, Roh GS.

Biochem Biophys Res Commun. 2018 May 23;499(4):1025-1031. doi: 10.1016/j.bbrc.2018.04.044. Epub 2018 Apr 10.

PMID:
29634925
6.

Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesis.

Singh AK, Aryal B, Chaube B, Rotllan N, Varela L, Horvath TL, Suárez Y, Fernández-Hernando C.

Mol Metab. 2018 May;11:59-69. doi: 10.1016/j.molmet.2018.03.011. Epub 2018 Mar 29.

7.

From white to beige: a new hypothalamic pathway.

Miletta MC, Horvath TL.

EMBO Rep. 2018 Apr;19(4). pii: e45928. doi: 10.15252/embr.201845928. Epub 2018 Mar 26. No abstract available.

PMID:
29581171
8.

Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.

Aryal B, Singh AK, Zhang X, Varela L, Rotllan N, Goedeke L, Chaube B, Camporez JP, Vatner DF, Horvath TL, Shulman GI, Suárez Y, Fernández-Hernando C.

JCI Insight. 2018 Mar 22;3(6). pii: 97918. doi: 10.1172/jci.insight.97918. [Epub ahead of print]

9.

Neuronal Cilia: Another Player in the Melanocortin System.

Varela L, Horvath TL.

Trends Mol Med. 2018 Apr;24(4):333-334. doi: 10.1016/j.molmed.2018.02.004. Epub 2018 Feb 28.

PMID:
29501261
10.

Type I interferons instigate fetal demise after Zika virus infection.

Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A.

Sci Immunol. 2018 Jan 5;3(19). pii: eaao1680. doi: 10.1126/sciimmunol.aao1680.

PMID:
29305462
11.

Molecular and cellular reorganization of neural circuits in the human lineage.

Sousa AMM, Zhu Y, Raghanti MA, Kitchen RR, Onorati M, Tebbenkamp ATN, Stutz B, Meyer KA, Li M, Kawasawa YI, Liu F, Perez RG, Mele M, Carvalho T, Skarica M, Gulden FO, Pletikos M, Shibata A, Stephenson AR, Edler MK, Ely JJ, Elsworth JD, Horvath TL, Hof PR, Hyde TM, Kleinman JE, Weinberger DR, Reimers M, Lifton RP, Mane SM, Noonan JP, State MW, Lein ES, Knowles JA, Marques-Bonet T, Sherwood CC, Gerstein MB, Sestan N.

Science. 2017 Nov 24;358(6366):1027-1032. doi: 10.1126/science.aan3456.

12.

Ghrelin is Related to Personality Differences in Reward Sensitivity and Impulsivity.

Ralevski E, Shanabrough M, Newcomb J, Gandelman E, Hayden R, Horvath TL, Petrakis I.

Alcohol Alcohol. 2018 Jan 1;53(1):52-56. doi: 10.1093/alcalc/agx082.

PMID:
29136100
13.

Cannabis in fat: high hopes to treat obesity.

Hawkins MN, Horvath TL.

J Clin Invest. 2017 Nov 1;127(11):3918-3920. doi: 10.1172/JCI97042. Epub 2017 Oct 16.

14.

Thyroid hormone- and estrogen receptor interactions with natural ligands and endocrine disruptors in the cerebellum.

Zsarnovszky A, Kiss D, Jocsak G, Nemeth G, Toth I, Horvath TL.

Front Neuroendocrinol. 2018 Jan;48:23-36. doi: 10.1016/j.yfrne.2017.10.001. Epub 2017 Oct 5. Review.

PMID:
28987779
15.

Comparative Medicine: An Inclusive Crossover Discipline.

Macy J, Horvath TL.

Yale J Biol Med. 2017 Sep 25;90(3):493-498. eCollection 2017 Sep. Review.

16.

Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons.

Suyama S, Ralevski A, Liu ZW, Dietrich MO, Yada T, Simonds SE, Cowley MA, Gao XB, Diano S, Horvath TL.

Elife. 2017 Aug 1;6. pii: e25755. doi: 10.7554/eLife.25755.

17.

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschöp MH, Heinig M, Trajkovski M, Haucke V, Poy MN.

Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19.

18.

Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.

Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A, Claret M.

Cell Metab. 2017 Jun 6;25(6):1390-1399.e6. doi: 10.1016/j.cmet.2017.05.010.

19.

Mitochondria Bioenergetic and Cognitive Functions: The Cannabinoid Link.

Mancini G, Horvath TL.

Trends Cell Biol. 2017 Jun;27(6):391-392. doi: 10.1016/j.tcb.2017.04.003. Epub 2017 May 6. Review.

PMID:
28487182
20.

Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol.

Ralevski E, Horvath TL, Shanabrough M, Hayden R, Newcomb J, Petrakis I.

Alcohol Alcohol. 2017 Jul 1;52(4):431-438. doi: 10.1093/alcalc/agx022.

PMID:
28481974
21.

Fetal Growth Restriction Caused by Sexual Transmission of Zika Virus in Mice.

Uraki R, Jurado KA, Hwang J, Szigeti-Buck K, Horvath TL, Iwasaki A, Fikrig E.

J Infect Dis. 2017 Jun 1;215(11):1720-1724. doi: 10.1093/infdis/jix204.

22.

Hypothalamic Agrp Neurons Drive Stereotypic Behaviors beyond Feeding.

Dietrich MO, Zimmer MR, Bober J, Horvath TL.

Cell. 2017 Apr 20;169(3):559. doi: 10.1016/j.cell.2017.04.006. No abstract available.

23.

Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus.

Morozov YM, Koch M, Rakic P, Horvath TL.

Mol Metab. 2017 Jan 27;6(4):374-381. doi: 10.1016/j.molmet.2017.01.004. eCollection 2017 Apr.

24.

Microglial Proliferation in Obesity: When, Where, Why, and What Does It Mean?

Chowen JA, Horvath TL, Argente J.

Diabetes. 2017 Apr;66(4):804-805. doi: 10.2337/dbi16-0073. No abstract available.

25.

Endothelial HIF-1α Enables Hypothalamic Glucose Uptake to Drive POMC Neurons.

Varela L, Suyama S, Huang Y, Shanabrough M, Tschöp MH, Gao XB, Giordano FJ, Horvath TL.

Diabetes. 2017 Jun;66(6):1511-1520. doi: 10.2337/db16-1106. Epub 2017 Mar 14.

26.

(S)Pot on Mitochondria: Cannabinoids Disrupt Cellular Respiration to Limit Neuronal Activity.

Harkany T, Horvath TL.

Cell Metab. 2017 Jan 10;25(1):8-10. doi: 10.1016/j.cmet.2016.12.020.

27.

Bisphenol A influences oestrogen- and thyroid hormone-regulated thyroid hormone receptor expression in rat cerebellar cell culture.

Somogyi V, Horváth TL, Tóth I, Bartha T, Frenyó LV, Kiss DS, Jócsák G, Kerti A, Naftolin F, Zsarnovszky A.

Acta Vet Hung. 2016 Dec;64(4):497-513.

PMID:
27993100
28.

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.

Romanov RA, Zeisel A, Bakker J, Girach F, Hellysaz A, Tomer R, Alpár A, Mulder J, Clotman F, Keimpema E, Hsueh B, Crow AK, Martens H, Schwindling C, Calvigioni D, Bains JS, Máté Z, Szabó G, Yanagawa Y, Zhang MD, Rendeiro A, Farlik M, Uhlén M, Wulff P, Bock C, Broberger C, Deisseroth K, Hökfelt T, Linnarsson S, Horvath TL, Harkany T.

Nat Neurosci. 2017 Feb;20(2):176-188. doi: 10.1038/nn.4462. Epub 2016 Dec 19.

PMID:
27991900
29.

Feeding Behavior: Hypocretin/Orexin Neurons Act between Food Seeking and Eating.

Gao XB, Horvath TL.

Curr Biol. 2016 Sep 26;26(18):R845-R847. doi: 10.1016/j.cub.2016.07.069.

30.

HSV-2 enhances ZIKV infection of the placenta and induces apoptosis in first-trimester trophoblast cells.

Aldo P, You Y, Szigeti K, Horvath TL, Lindenbach B, Mor G.

Am J Reprod Immunol. 2016 Nov;76(5):348-357. doi: 10.1111/aji.12578. Epub 2016 Sep 10.

PMID:
27613665
31.

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.

Onorati M, Li Z, Liu F, Sousa AMM, Nakagawa N, Li M, Dell'Anno MT, Gulden FO, Pochareddy S, Tebbenkamp ATN, Han W, Pletikos M, Gao T, Zhu Y, Bichsel C, Varela L, Szigeti-Buck K, Lisgo S, Zhang Y, Testen A, Gao XB, Mlakar J, Popovic M, Flamand M, Strittmatter SM, Kaczmarek LK, Anton ES, Horvath TL, Lindenbach BD, Sestan N.

Cell Rep. 2016 Sep 6;16(10):2576-2592. doi: 10.1016/j.celrep.2016.08.038. Epub 2016 Aug 24.

32.

Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.

Yockey LJ, Varela L, Rakib T, Khoury-Hanold W, Fink SL, Stutz B, Szigeti-Buck K, Van den Pol A, Lindenbach BD, Horvath TL, Iwasaki A.

Cell. 2016 Aug 25;166(5):1247-1256.e4. doi: 10.1016/j.cell.2016.08.004.

33.

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.

García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH.

Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028.

34.

Caloric restriction of db/db mice reverts hepatic steatosis and body weight with divergent hepatic metabolism.

Kim KE, Jung Y, Min S, Nam M, Heo RW, Jeon BT, Song DH, Yi CO, Jeong EA, Kim H, Kim J, Jeong SY, Kwak W, Ryu do H, Horvath TL, Roh GS, Hwang GS.

Sci Rep. 2016 Jul 21;6:30111. doi: 10.1038/srep30111.

35.

Hypothalamic TLR2 triggers sickness behavior via a microglia-neuronal axis.

Jin S, Kim JG, Park JW, Koch M, Horvath TL, Lee BJ.

Sci Rep. 2016 Jul 12;6:29424. doi: 10.1038/srep29424.

36.

Comparison of Individual and Combined Effects of Four Endocrine Disruptors on Estrogen Receptor Beta Transcription in Cerebellar Cell Culture: The Modulatory Role of Estradiol and Triiodo-Thyronine.

Jocsak G, Kiss DS, Toth I, Goszleth G, Bartha T, Frenyo LV, Horvath TL, Zsarnovszky A.

Int J Environ Res Public Health. 2016 Jun 22;13(6). pii: E619. doi: 10.3390/ijerph13060619.

37.

Viral Spread to Enteric Neurons Links Genital HSV-1 Infection to Toxic Megacolon and Lethality.

Khoury-Hanold W, Yordy B, Kong P, Kong Y, Ge W, Szigeti-Buck K, Ralevski A, Horvath TL, Iwasaki A.

Cell Host Microbe. 2016 Jun 8;19(6):788-99. doi: 10.1016/j.chom.2016.05.008.

38.

Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation.

Hermes G, Nagy D, Waterson M, Zsarnovszky A, Varela L, Hajos M, Horvath TL.

Mol Metab. 2016 Apr 9;5(6):415-421. doi: 10.1016/j.molmet.2016.04.002. eCollection 2016 Jun.

39.

The role of astrocytes in the hypothalamic response and adaptation to metabolic signals.

Chowen JA, Argente-Arizón P, Freire-Regatillo A, Frago LM, Horvath TL, Argente J.

Prog Neurobiol. 2016 Sep;144:68-87. doi: 10.1016/j.pneurobio.2016.03.001. Epub 2016 Mar 18. Review.

PMID:
27000556
40.

Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.

Zhang Y, Zhang XF, Fleming MR, Amiri A, El-Hassar L, Surguchev AA, Hyland C, Jenkins DP, Desai R, Brown MR, Gazula VR, Waters MF, Large CH, Horvath TL, Navaratnam D, Vaccarino FM, Forscher P, Kaczmarek LK.

Cell. 2016 Apr 7;165(2):434-448. doi: 10.1016/j.cell.2016.02.009. Epub 2016 Mar 17.

41.

Mitochondrial Uncoupling Protein 2 (UCP2) Regulates Retinal Ganglion Cell Number and Survival.

Barnstable CJ, Reddy R, Li H, Horvath TL.

J Mol Neurosci. 2016 Apr;58(4):461-9. doi: 10.1007/s12031-016-0728-5. Epub 2016 Feb 5.

42.

Mitochondria controlled by UCP2 determine hypoxia-induced synaptic remodeling in the cortex and hippocampus.

Varela L, Schwartz ML, Horvath TL.

Neurobiol Dis. 2016 Jun;90:68-74. doi: 10.1016/j.nbd.2016.01.004. Epub 2016 Jan 9.

PMID:
26777666
43.

Metabolism and Mental Illness.

Sestan-Pesa M, Horvath TL.

Trends Mol Med. 2016 Feb;22(2):174-183. doi: 10.1016/j.molmed.2015.12.003. Epub 2016 Jan 14. Review.

PMID:
26776095
44.

Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution.

Youm YH, Horvath TL, Mangelsdorf DJ, Kliewer SA, Dixit VD.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1026-31. doi: 10.1073/pnas.1514511113. Epub 2016 Jan 11.

45.

Synaptic lipids in cortical function and psychiatric disorders.

Stutz B, Horvath TL.

EMBO Mol Med. 2016 Jan 1;8(1):3-5. doi: 10.15252/emmm.201505749. No abstract available.

46.

Calcineurin Aγ is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis.

Cottrell JR, Li B, Kyung JW, Ashford CJ, Mann JJ, Horvath TL, Ryan TA, Kim SH, Gerber DJ.

J Biol Chem. 2016 Jan 22;291(4):1948-56. doi: 10.1074/jbc.M115.705319. Epub 2015 Dec 1.

47.

Neuronal Regulation of Energy Homeostasis: Beyond the Hypothalamus and Feeding.

Waterson MJ, Horvath TL.

Cell Metab. 2015 Dec 1;22(6):962-70. doi: 10.1016/j.cmet.2015.09.026. Epub 2015 Oct 22. Review.

48.

Reducing Adiposity in a Critical Developmental Window Has Lasting Benefits in Mice.

Lerea JS, Ring LE, Hassouna R, Chong AC, Szigeti-Buck K, Horvath TL, Zeltser LM.

Endocrinology. 2016 Feb;157(2):666-78. doi: 10.1210/en.2015-1753. Epub 2015 Nov 20.

49.

Mitochondrial ROS signaling in organismal homeostasis.

Shadel GS, Horvath TL.

Cell. 2015 Oct 22;163(3):560-9. doi: 10.1016/j.cell.2015.10.001. Epub 2015 Oct 22. Review.

50.

AgRP Neurons Regulate Bone Mass.

Kim JG, Sun BH, Dietrich MO, Koch M, Yao GQ, Diano S, Insogna K, Horvath TL.

Cell Rep. 2015 Oct 6;13(1):8-14. doi: 10.1016/j.celrep.2015.08.070. Epub 2015 Sep 24.

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