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Items: 1 to 50 of 294

1.

Parallel Paths in PVH Control of Feeding.

Varela L, Horvath TL.

Neuron. 2019 May 8;102(3):514-516. doi: 10.1016/j.neuron.2019.04.026.

PMID:
31071283
2.

Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight.

Mancini G, Pirruccio K, Yang X, Blüher M, Rodeheffer M, Horvath TL.

Cell Rep. 2019 Apr 9;27(2):648. doi: 10.1016/j.celrep.2019.03.065. No abstract available.

3.

Prefrontal Cortical and Behavioral Adaptations to Surgical Delivery Mediated by Metabolic Principles.

Taylor-Giorlando M, Scheinost D, Ment L, Rothman D, Horvath TL.

Cereb Cortex. 2019 Mar 16. pii: bhz046. doi: 10.1093/cercor/bhz046. [Epub ahead of print]

PMID:
30877804
4.

Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight.

Mancini G, Pirruccio K, Yang X, Blüher M, Rodeheffer M, Horvath TL.

Cell Rep. 2019 Mar 12;26(11):2849-2858.e4. doi: 10.1016/j.celrep.2019.02.039. Erratum in: Cell Rep. 2019 Apr 9;27(2):648.

5.

Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity.

Stutz B, Nasrallah C, Nigro M, Curry D, Liu ZW, Gao XB, Elsworth JD, Mintz L, Horvath TL.

Mol Metab. 2019 Jun;24:120-138. doi: 10.1016/j.molmet.2019.02.005. Epub 2019 Feb 21.

6.

Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging.

Seli E, Wang T, Horvath TL.

Fertil Steril. 2019 Feb;111(2):197-204. doi: 10.1016/j.fertnstert.2018.11.048. Review.

PMID:
30691623
7.

Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism.

García-Cáceres C, Balland E, Prevot V, Luquet S, Woods SC, Koch M, Horvath TL, Yi CX, Chowen JA, Verkhratsky A, Araque A, Bechmann I, Tschöp MH.

Nat Neurosci. 2019 Jan;22(1):7-14. doi: 10.1038/s41593-018-0286-y. Epub 2018 Dec 10. Review.

PMID:
30531847
8.

Effects of myeloid sirtuin 1 deficiency on hypothalamic neurogranin in mice fed a high-fat diet.

Kim KE, Jeong EA, Shin HJ, Lee JY, Choi EB, An HS, Park KA, Jin Z, Lee DK, Horvath TL, Roh GS.

Biochem Biophys Res Commun. 2019 Jan 1;508(1):123-129. doi: 10.1016/j.bbrc.2018.11.126. Epub 2018 Nov 22.

9.

Aromatase and estrogen receptor immunoreactivity in the coronary arteries of monkeys and human subjects.

Diano S, Horvath TL, Mor G, Register T, Adams M, Harada N, Naftolin F.

Menopause. 2018 Nov;25(11):1201-1207. doi: 10.1097/GME.0000000000001219.

PMID:
30358714
10.

The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development.

Tebbenkamp ATN, Varela L, Choi J, Paredes MI, Giani AM, Song JE, Sestan-Pesa M, Franjic D, Sousa AMM, Liu ZW, Li M, Bichsel C, Koch M, Szigeti-Buck K, Liu F, Li Z, Kawasawa YI, Paspalas CD, Mineur YS, Prontera P, Merla G, Picciotto MR, Arnsten AFT, Horvath TL, Sestan N.

Cell. 2018 Nov 1;175(4):1088-1104.e23. doi: 10.1016/j.cell.2018.09.014.

11.

Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity.

Timper K, Paeger L, Sánchez-Lasheras C, Varela L, Jais A, Nolte H, Vogt MC, Hausen AC, Heilinger C, Evers N, Pospisilik JA, Penninger JM, Taylor EB, Horvath TL, Kloppenburg P, Brüning JC.

Cell Rep. 2018 Oct 9;25(2):383-397.e10. doi: 10.1016/j.celrep.2018.09.034.

12.

Neurophysiological signals as predictive translational biomarkers for Alzheimer's disease treatment: effects of donepezil on neuronal network oscillations in TgF344-AD rats.

Stoiljkovic M, Kelley C, Horvath TL, Hajós M.

Alzheimers Res Ther. 2018 Oct 10;10(1):105. doi: 10.1186/s13195-018-0433-4.

13.

Insulin regulates POMC neuronal plasticity to control glucose metabolism.

Dodd GT, Michael NJ, Lee-Young RS, Mangiafico SP, Pryor JT, Munder AC, Simonds SE, Brüning JC, Zhang ZY, Cowley MA, Andrikopoulos S, Horvath TL, Spanswick D, Tiganis T.

Elife. 2018 Sep 19;7. pii: e38704. doi: 10.7554/eLife.38704.

14.

Metabolic regulation and glucose sensitivity of cortical radial glial cells.

Rash BG, Micali N, Huttner AJ, Morozov YM, Horvath TL, Rakic P.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10142-10147. doi: 10.1073/pnas.1808066115. Epub 2018 Sep 17.

15.

Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress.

Alpár A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, Pifl C, Zachar G, Perugini J, Severi I, Leitgeb P, Bakker J, Miklosi AG, Tretiakov E, Keimpema E, Arque G, Tasan RO, Sperk G, Malenczyk K, Máté Z, Erdélyi F, Szabó G, Lubec G, Palkovits M, Giordano A, Hökfelt TG, Romanov RA, Horvath TL, Harkany T.

EMBO J. 2018 Nov 2;37(21). pii: e100087. doi: 10.15252/embj.2018100087. Epub 2018 Sep 12.

16.

Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity.

Ravussin A, Youm YH, Sander J, Ryu S, Nguyen K, Varela L, Shulman GI, Sidorov S, Horvath TL, Schultze JL, Dixit VD.

Cell Rep. 2018 Jul 31;24(5):1085-1092.e6. doi: 10.1016/j.celrep.2018.06.112.

17.

Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer's Disease Pathology.

Stoiljkovic M, Kelley C, Stutz B, Horvath TL, Hajós M.

Cereb Cortex. 2019 Jun 1;29(6):2716-2727. doi: 10.1093/cercor/bhy140.

PMID:
29920597
18.

Viral Vectors for Studying Brain Mechanisms that Control Energy Homeostasis.

Mancini G, Horvath TL.

Cell Metab. 2018 Jun 5;27(6):1168-1175. doi: 10.1016/j.cmet.2018.05.015. Review.

19.

Comparative Analysis of Zearalenone Effects on Thyroid Receptor Alpha (TRα) and Beta (TRβ) Expression in Rat Primary Cerebellar Cell Cultures.

Kiss DS, Ioja E, Toth I, Barany Z, Jocsak G, Bartha T, Horvath TL, Zsarnovszky A.

Int J Mol Sci. 2018 May 11;19(5). pii: E1440. doi: 10.3390/ijms19051440.

20.

Patient-Derived iPSC-Hypothamic Neurons: The Ultimate Protocol.

Miletta MC, Horvath TL.

Cell Stem Cell. 2018 May 3;22(5):615-616. doi: 10.1016/j.stem.2018.04.019.

21.

Myeloid sirtuin1 deficiency aggravates hippocampal inflammation in mice fed high-fat diets.

Kim KE, Jeong EA, Lee JY, Yi CO, Park KA, Jin Z, Lee JE, Horvath TL, Roh GS.

Biochem Biophys Res Commun. 2018 May 23;499(4):1025-1031. doi: 10.1016/j.bbrc.2018.04.044. Epub 2018 Apr 10.

PMID:
29634925
22.

Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesis.

Singh AK, Aryal B, Chaube B, Rotllan N, Varela L, Horvath TL, Suárez Y, Fernández-Hernando C.

Mol Metab. 2018 May;11:59-69. doi: 10.1016/j.molmet.2018.03.011. Epub 2018 Mar 29.

23.

From white to beige: a new hypothalamic pathway.

Miletta MC, Horvath TL.

EMBO Rep. 2018 Apr;19(4). pii: e45928. doi: 10.15252/embr.201845928. Epub 2018 Mar 26. No abstract available.

24.

Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.

Aryal B, Singh AK, Zhang X, Varela L, Rotllan N, Goedeke L, Chaube B, Camporez JP, Vatner DF, Horvath TL, Shulman GI, Suárez Y, Fernández-Hernando C.

JCI Insight. 2018 Mar 22;3(6). pii: 97918. doi: 10.1172/jci.insight.97918.

25.

Neuronal Cilia: Another Player in the Melanocortin System.

Varela L, Horvath TL.

Trends Mol Med. 2018 Apr;24(4):333-334. doi: 10.1016/j.molmed.2018.02.004. Epub 2018 Feb 28.

PMID:
29501261
26.

Type I interferons instigate fetal demise after Zika virus infection.

Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A.

Sci Immunol. 2018 Jan 5;3(19). pii: eaao1680. doi: 10.1126/sciimmunol.aao1680.

27.

Molecular and cellular reorganization of neural circuits in the human lineage.

Sousa AMM, Zhu Y, Raghanti MA, Kitchen RR, Onorati M, Tebbenkamp ATN, Stutz B, Meyer KA, Li M, Kawasawa YI, Liu F, Perez RG, Mele M, Carvalho T, Skarica M, Gulden FO, Pletikos M, Shibata A, Stephenson AR, Edler MK, Ely JJ, Elsworth JD, Horvath TL, Hof PR, Hyde TM, Kleinman JE, Weinberger DR, Reimers M, Lifton RP, Mane SM, Noonan JP, State MW, Lein ES, Knowles JA, Marques-Bonet T, Sherwood CC, Gerstein MB, Sestan N.

Science. 2017 Nov 24;358(6366):1027-1032. doi: 10.1126/science.aan3456.

28.

Ghrelin is Related to Personality Differences in Reward Sensitivity and Impulsivity.

Ralevski E, Shanabrough M, Newcomb J, Gandelman E, Hayden R, Horvath TL, Petrakis I.

Alcohol Alcohol. 2018 Jan 1;53(1):52-56. doi: 10.1093/alcalc/agx082.

PMID:
29136100
29.

Cannabis in fat: high hopes to treat obesity.

Hawkins MN, Horvath TL.

J Clin Invest. 2017 Nov 1;127(11):3918-3920. doi: 10.1172/JCI97042. Epub 2017 Oct 16.

30.

Thyroid hormone- and estrogen receptor interactions with natural ligands and endocrine disruptors in the cerebellum.

Zsarnovszky A, Kiss D, Jocsak G, Nemeth G, Toth I, Horvath TL.

Front Neuroendocrinol. 2018 Jan;48:23-36. doi: 10.1016/j.yfrne.2017.10.001. Epub 2017 Oct 5. Review.

PMID:
28987779
31.

Comparative Medicine: An Inclusive Crossover Discipline.

Macy J, Horvath TL.

Yale J Biol Med. 2017 Sep 25;90(3):493-498. eCollection 2017 Sep. Review.

32.

Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons.

Suyama S, Ralevski A, Liu ZW, Dietrich MO, Yada T, Simonds SE, Cowley MA, Gao XB, Diano S, Horvath TL.

Elife. 2017 Aug 1;6. pii: e25755. doi: 10.7554/eLife.25755.

33.

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschöp MH, Heinig M, Trajkovski M, Haucke V, Poy MN.

Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19.

34.

Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.

Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A, Claret M.

Cell Metab. 2017 Jun 6;25(6):1390-1399.e6. doi: 10.1016/j.cmet.2017.05.010.

35.

Mitochondria Bioenergetic and Cognitive Functions: The Cannabinoid Link.

Mancini G, Horvath TL.

Trends Cell Biol. 2017 Jun;27(6):391-392. doi: 10.1016/j.tcb.2017.04.003. Epub 2017 May 6. Review.

PMID:
28487182
36.

Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol.

Ralevski E, Horvath TL, Shanabrough M, Hayden R, Newcomb J, Petrakis I.

Alcohol Alcohol. 2017 Jul 1;52(4):431-438. doi: 10.1093/alcalc/agx022.

PMID:
28481974
37.

Fetal Growth Restriction Caused by Sexual Transmission of Zika Virus in Mice.

Uraki R, Jurado KA, Hwang J, Szigeti-Buck K, Horvath TL, Iwasaki A, Fikrig E.

J Infect Dis. 2017 Jun 1;215(11):1720-1724. doi: 10.1093/infdis/jix204.

38.

Hypothalamic Agrp Neurons Drive Stereotypic Behaviors beyond Feeding.

Dietrich MO, Zimmer MR, Bober J, Horvath TL.

Cell. 2017 Apr 20;169(3):559. doi: 10.1016/j.cell.2017.04.006. No abstract available.

39.

Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus.

Morozov YM, Koch M, Rakic P, Horvath TL.

Mol Metab. 2017 Jan 27;6(4):374-381. doi: 10.1016/j.molmet.2017.01.004. eCollection 2017 Apr.

40.

Microglial Proliferation in Obesity: When, Where, Why, and What Does It Mean?

Chowen JA, Horvath TL, Argente J.

Diabetes. 2017 Apr;66(4):804-805. doi: 10.2337/dbi16-0073. No abstract available.

41.

Endothelial HIF-1α Enables Hypothalamic Glucose Uptake to Drive POMC Neurons.

Varela L, Suyama S, Huang Y, Shanabrough M, Tschöp MH, Gao XB, Giordano FJ, Horvath TL.

Diabetes. 2017 Jun;66(6):1511-1520. doi: 10.2337/db16-1106. Epub 2017 Mar 14.

42.

(S)Pot on Mitochondria: Cannabinoids Disrupt Cellular Respiration to Limit Neuronal Activity.

Harkany T, Horvath TL.

Cell Metab. 2017 Jan 10;25(1):8-10. doi: 10.1016/j.cmet.2016.12.020.

43.

Bisphenol A influences oestrogen- and thyroid hormone-regulated thyroid hormone receptor expression in rat cerebellar cell culture.

Somogyi V, Horváth TL, Tóth I, Bartha T, Frenyó LV, Kiss DS, Jócsák G, Kerti A, Naftolin F, Zsarnovszky A.

Acta Vet Hung. 2016 Dec;64(4):497-513.

PMID:
27993100
44.

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.

Romanov RA, Zeisel A, Bakker J, Girach F, Hellysaz A, Tomer R, Alpár A, Mulder J, Clotman F, Keimpema E, Hsueh B, Crow AK, Martens H, Schwindling C, Calvigioni D, Bains JS, Máté Z, Szabó G, Yanagawa Y, Zhang MD, Rendeiro A, Farlik M, Uhlén M, Wulff P, Bock C, Broberger C, Deisseroth K, Hökfelt T, Linnarsson S, Horvath TL, Harkany T.

Nat Neurosci. 2017 Feb;20(2):176-188. doi: 10.1038/nn.4462. Epub 2016 Dec 19.

PMID:
27991900
45.

Feeding Behavior: Hypocretin/Orexin Neurons Act between Food Seeking and Eating.

Gao XB, Horvath TL.

Curr Biol. 2016 Sep 26;26(18):R845-R847. doi: 10.1016/j.cub.2016.07.069.

46.

HSV-2 enhances ZIKV infection of the placenta and induces apoptosis in first-trimester trophoblast cells.

Aldo P, You Y, Szigeti K, Horvath TL, Lindenbach B, Mor G.

Am J Reprod Immunol. 2016 Nov;76(5):348-357. doi: 10.1111/aji.12578. Epub 2016 Sep 10.

PMID:
27613665
47.

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.

Onorati M, Li Z, Liu F, Sousa AMM, Nakagawa N, Li M, Dell'Anno MT, Gulden FO, Pochareddy S, Tebbenkamp ATN, Han W, Pletikos M, Gao T, Zhu Y, Bichsel C, Varela L, Szigeti-Buck K, Lisgo S, Zhang Y, Testen A, Gao XB, Mlakar J, Popovic M, Flamand M, Strittmatter SM, Kaczmarek LK, Anton ES, Horvath TL, Lindenbach BD, Sestan N.

Cell Rep. 2016 Sep 6;16(10):2576-2592. doi: 10.1016/j.celrep.2016.08.038. Epub 2016 Aug 24.

48.

Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.

Yockey LJ, Varela L, Rakib T, Khoury-Hanold W, Fink SL, Stutz B, Szigeti-Buck K, Van den Pol A, Lindenbach BD, Horvath TL, Iwasaki A.

Cell. 2016 Aug 25;166(5):1247-1256.e4. doi: 10.1016/j.cell.2016.08.004.

49.

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.

García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH.

Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028.

50.

Caloric restriction of db/db mice reverts hepatic steatosis and body weight with divergent hepatic metabolism.

Kim KE, Jung Y, Min S, Nam M, Heo RW, Jeon BT, Song DH, Yi CO, Jeong EA, Kim H, Kim J, Jeong SY, Kwak W, Ryu do H, Horvath TL, Roh GS, Hwang GS.

Sci Rep. 2016 Jul 21;6:30111. doi: 10.1038/srep30111.

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