Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 106


RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination.

Quicke KM, Kim KY, Horvath CM, Suthar MS.

J Interferon Cytokine Res. 2019 Nov;39(11):669-683. doi: 10.1089/jir.2019.0059. Epub 2019 Jun 25.


Transcriptional and chromatin regulation in interferon and innate antiviral gene expression.

Au-Yeung N, Horvath CM.

Cytokine Growth Factor Rev. 2018 Dec;44:11-17. doi: 10.1016/j.cytogfr.2018.10.003. Epub 2018 Oct 22. Review.


IFN-γ-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5.

Saleiro D, Blyth GT, Kosciuczuk EM, Ozark PA, Majchrzak-Kita B, Arslan AD, Fischietti M, Reddy NK, Horvath CM, Davis RJ, Fish EN, Platanias LC.

Sci Signal. 2018 Nov 20;11(557). pii: eaap9921. doi: 10.1126/scisignal.aap9921.


Sendai Virus Infection Induces Expression of Novel RNAs in Human Cells.

Mandhana R, Horvath CM.

Sci Rep. 2018 Nov 14;8(1):16815. doi: 10.1038/s41598-018-35231-8.


Histone H2A.Z Suppression of Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2.

Au-Yeung N, Horvath CM.

iScience. 2018 Aug 31;6:68-82. doi: 10.1016/j.isci.2018.07.013. Epub 2018 Jul 20.


Constitutively Active MDA5 Proteins Are Inhibited by Paramyxovirus V Proteins.

Mandhana R, Qian LK, Horvath CM.

J Interferon Cytokine Res. 2018 Aug;38(8):319-332. doi: 10.1089/jir.2018.0049.


RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.

Parisien JP, Lenoir JJ, Mandhana R, Rodriguez KR, Qian K, Bruns AM, Horvath CM.

EMBO Rep. 2018 Jun;19(6). pii: e45176. doi: 10.15252/embr.201745176. Epub 2018 Apr 16.


Prevalence and Prediction of Obstructive Sleep Apnea Prior to Bariatric Surgery-Gender-Specific Performance of Four Sleep Questionnaires.

Horvath CM, Jossen J, Kröll D, Nett PC, Baty F, Brill AK, Ott SR.

Obes Surg. 2018 Sep;28(9):2720-2726. doi: 10.1007/s11695-018-3222-z.


Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G.

Pollpeter D, Parsons M, Sobala AE, Coxhead S, Lang RD, Bruns AM, Papaioannou S, McDonnell JM, Apolonia L, Chowdhury JA, Horvath CM, Malim MH.

Nat Microbiol. 2018 Feb;3(2):220-233. doi: 10.1038/s41564-017-0063-9. Epub 2017 Nov 20.


A 58-Year-Old Man With Position-Dependent Nocturnal Dyspnea.

Schertel A, Horvath CM, Pichler Hefti J, Aubert JD, Brill AK.

Chest. 2017 Aug;152(2):e51-e55. doi: 10.1016/j.chest.2017.03.014.


Transcutaneous versus blood carbon dioxide monitoring during acute noninvasive ventilation in the emergency department - a retrospective analysis.

Horvath CM, Brutsche MH, Baty F, Rüdiger JJ.

Swiss Med Wkly. 2016 Oct 26;146:w14373. doi: 10.4414/smw.2016.14373. eCollection 2016.


Erratum to: NIV by an interdisciplinary respiratory care team in severe respiratory failure in the emergency department limited to day time hours.

Horvath CM, Brutsche MH, Schoch OD, Schillig B, Baty F, vonOw D, Rüdiger JJ.

Intern Emerg Med. 2017 Dec;12(8):1339. doi: 10.1007/s11739-016-1569-5. No abstract available.


NIV by an interdisciplinary respiratory care team in severe respiratory failure in the emergency department limited to day time hours.

Horvath CM, Brutsche MH, Schoch OD, Schillig B, Baty F, vonOw D, Rüdiger JJ.

Intern Emerg Med. 2017 Dec;12(8):1215-1223. doi: 10.1007/s11739-016-1546-z. Epub 2016 Oct 8. Erratum in: Intern Emerg Med. 2017 Dec;12 (8):1339. Brutsche, Martin Horvath [corrected to Brutsche, Martin Hugo].


The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection.

Komuro A, Homma Y, Negoro T, Barber GN, Horvath CM.

Biochem Biophys Res Commun. 2016 Nov 11;480(2):187-193. doi: 10.1016/j.bbrc.2016.10.023. Epub 2016 Oct 13.


A 43-Year-Old Man With Daytime Sleepiness and a Heart Murmur.

Horvath CM, Zbinden S, Ott SR, Brill AK.

Chest. 2016 Oct;150(4):e117-e120. doi: 10.1016/j.chest.2016.03.039.


Pan-cancer analysis of TCGA data reveals notable signaling pathways.

Neapolitan R, Horvath CM, Jiang X.

BMC Cancer. 2015 Jul 14;15:516. doi: 10.1186/s12885-015-1484-6.


Editorial overview: Antiviral strategies.

Gale M Jr, Horvath CM.

Curr Opin Virol. 2015 Jun;12:v-vii. doi: 10.1016/j.coviro.2015.05.001. Epub 2015 May 23. No abstract available.


LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling.

Bruns AM, Horvath CM.

Cytokine. 2015 Aug;74(2):198-206. doi: 10.1016/j.cyto.2015.02.010. Epub 2015 Mar 18. Review.


A serpin takes a bite out of the flu.

Horvath CM.

Cell Host Microbe. 2015 Mar 11;17(3):283-284. doi: 10.1016/j.chom.2015.02.018.


[ARDS after Incidental Aspiration of Petroleum in an Adult].

Horvath CM, Schneider T, Kluckert T, Brutsche MH.

Pneumologie. 2015 Jun;69(6):341-4. doi: 10.1055/s-0034-1391377. Epub 2015 Jan 28. German.


Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors.

Tell RW, Horvath CM.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12787-92. doi: 10.1073/pnas.1404881111. Epub 2014 Aug 19.


The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly.

Bruns AM, Leser GP, Lamb RA, Horvath CM.

Mol Cell. 2014 Sep 4;55(5):771-81. doi: 10.1016/j.molcel.2014.07.003. Epub 2014 Aug 7.


Antiviral RNA recognition and assembly by RLR family innate immune sensors.

Bruns AM, Horvath CM.

Cytokine Growth Factor Rev. 2014 Oct;25(5):507-12. doi: 10.1016/j.cytogfr.2014.07.006. Epub 2014 Jul 15. Review.


MDA5 and LGP2: accomplices and antagonists of antiviral signal transduction.

Rodriguez KR, Bruns AM, Horvath CM.

J Virol. 2014 Aug;88(15):8194-200. doi: 10.1128/JVI.00640-14. Epub 2014 May 21. Review.


High-density nucleosome occupancy map of human chromosome 9p21-22 reveals chromatin organization of the type I interferon gene cluster.

Freaney JE, Zhang Q, Yigit E, Kim R, Widom J, Wang JP, Horvath CM.

J Interferon Cytokine Res. 2014 Sep;34(9):676-85. doi: 10.1089/jir.2013.0118. Epub 2014 Mar 27.


Small RNA profiling of influenza A virus-infected cells identifies miR-449b as a regulator of histone deacetylase 1 and interferon beta.

Buggele WA, Krause KE, Horvath CM.

PLoS One. 2013 Sep 26;8(9):e76560. doi: 10.1371/journal.pone.0076560. eCollection 2013.


Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway.

Au-Yeung N, Mandhana R, Horvath CM.

JAKSTAT. 2013 Jul 1;2(3):e23931. doi: 10.4161/jkst.23931. Epub 2013 Jun 18. Review.


Extensive cooperation of immune master regulators IRF3 and NFκB in RNA Pol II recruitment and pause release in human innate antiviral transcription.

Freaney JE, Kim R, Mandhana R, Horvath CM.

Cell Rep. 2013 Sep 12;4(5):959-73. doi: 10.1016/j.celrep.2013.07.043. Epub 2013 Aug 29.


MicroRNA profiling of Sendai virus-infected A549 cells identifies miR-203 as an interferon-inducible regulator of IFIT1/ISG56.

Buggele WA, Horvath CM.

J Virol. 2013 Aug;87(16):9260-70. doi: 10.1128/JVI.01064-13. Epub 2013 Jun 19.


A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory.

Light WH, Freaney J, Sood V, Thompson A, D'Urso A, Horvath CM, Brickner JH.

PLoS Biol. 2013;11(3):e1001524. doi: 10.1371/journal.pbio.1001524. Epub 2013 Mar 26.


Detection of activated STAT proteins.

Parisien JP, Horvath CM.

Methods Mol Biol. 2013;967:135-45. doi: 10.1007/978-1-62703-242-1_9.


Amino acid requirements for MDA5 and LGP2 recognition by paramyxovirus V proteins: a single arginine distinguishes MDA5 from RIG-I.

Rodriguez KR, Horvath CM.

J Virol. 2013 Mar;87(5):2974-8. doi: 10.1128/JVI.02843-12. Epub 2012 Dec 26.


ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2).

Bruns AM, Pollpeter D, Hadizadeh N, Myong S, Marko JF, Horvath CM.

J Biol Chem. 2013 Jan 11;288(2):938-46. doi: 10.1074/jbc.M112.424416. Epub 2012 Nov 26.


Influenza A virus infection of human respiratory cells induces primary microRNA expression.

Buggele WA, Johnson KE, Horvath CM.

J Biol Chem. 2012 Sep 7;287(37):31027-40. doi: 10.1074/jbc.M112.387670. Epub 2012 Jul 20.


Activation of RIG-I-like receptor signal transduction.

Bruns AM, Horvath CM.

Crit Rev Biochem Mol Biol. 2012 Mar-Apr;47(2):194-206. doi: 10.3109/10409238.2011.630974. Epub 2011 Nov 8. Review.


Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein.

Pollpeter D, Komuro A, Barber GN, Horvath CM.

PLoS One. 2011 Apr 14;6(4):e18842. doi: 10.1371/journal.pone.0018842.


Regulating immune response using polyvalent nucleic acid-gold nanoparticle conjugates.

Massich MD, Giljohann DA, Seferos DS, Ludlow LE, Horvath CM, Mirkin CA.

Mol Pharm. 2009 Nov-Dec;6(6):1934-40. doi: 10.1021/mp900172m.


Paramyxovirus disruption of interferon signal transduction: STATus report.

Ramachandran A, Horvath CM.

J Interferon Cytokine Res. 2009 Sep;29(9):531-7. doi: 10.1089/jir.2009.0070. Review.


A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2.

Parisien JP, Bamming D, Komuro A, Ramachandran A, Rodriguez JJ, Barber G, Wojahn RD, Horvath CM.

J Virol. 2009 Jul;83(14):7252-60. doi: 10.1128/JVI.00153-09. Epub 2009 Apr 29.


A point mutation, E95D, in the mumps virus V protein disengages STAT3 targeting from STAT1 targeting.

Puri M, Lemon K, Duprex WP, Rima BK, Horvath CM.

J Virol. 2009 Jul;83(13):6347-56. doi: 10.1128/JVI.00596-09. Epub 2009 Apr 22.


Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2.

Bamming D, Horvath CM.

J Biol Chem. 2009 Apr 10;284(15):9700-12. doi: 10.1074/jbc.M807365200. Epub 2009 Feb 11.


Negative regulation of cytoplasmic RNA-mediated antiviral signaling.

Komuro A, Bamming D, Horvath CM.

Cytokine. 2008 Sep;43(3):350-8. doi: 10.1016/j.cyto.2008.07.011. Epub 2008 Aug 13. Review.


The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.

Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT.

EMBO Rep. 2008 Sep;9(9):930-6. doi: 10.1038/embor.2008.136. Epub 2008 Jul 18.


STAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibition.

Ramachandran A, Parisien JP, Horvath CM.

J Virol. 2008 Sep;82(17):8330-8. doi: 10.1128/JVI.00831-08. Epub 2008 Jun 25.


Henipavirus V protein association with Polo-like kinase reveals functional overlap with STAT1 binding and interferon evasion.

Ludlow LE, Lo MK, Rodriguez JJ, Rota PA, Horvath CM.

J Virol. 2008 Jul;82(13):6259-71. doi: 10.1128/JVI.00409-08. Epub 2008 Apr 16.


Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1.

Lu LL, Puri M, Horvath CM, Sen GC.

J Biol Chem. 2008 May 23;283(21):14269-76. doi: 10.1074/jbc.M710089200. Epub 2008 Mar 24.


Enabled interferon signaling evasion in an immune-competent transgenic mouse model of parainfluenza virus 5 infection.

Kraus TA, Garza L, Horvath CM.

Virology. 2008 Feb 5;371(1):196-205. Epub 2007 Oct 26.


RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2.

Komuro A, Horvath CM.

J Virol. 2006 Dec;80(24):12332-42. Epub 2006 Oct 4.

Supplemental Content

Loading ...
Support Center