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Items: 39


Variability in chest compression rate calculations during pediatric cardiopulmonary resuscitation.

Landis WP, Morgan RW, Reeder RW, Graham K, Siems A, Diddle JW, Pollack MM, Maa T, Fernandez RP, Yates AR, Tilford B, Ahmed T, Meert KL, Schneiter C, Bishop R, Mourani PM, Naim MY, Friess S, Burns C, Manga A, Franzon D, Tabbutt S, McQuillen PS, Horvat CM, Bochkoris M, Carcillo JA, Huard L, Federman M, Sapru A, Viteri S, Hehir DA, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Wolfe HA, Sutton RM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators the National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators.

Resuscitation. 2020 Apr;149:127-133. doi: 10.1016/j.resuscitation.2020.01.040. Epub 2020 Feb 20.


Early Hyperoxemia and Outcome Among Critically Ill Children.

Ramgopal S, Dezfulian C, Hickey RW, Au AK, Venkataraman S, Clark RSB, Horvat CM.

Pediatr Crit Care Med. 2020 Feb;21(2):e129-e132. doi: 10.1097/PCC.0000000000002203.


Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit.

Ramgopal S, Dezfulian C, Hickey RW, Au AK, Venkataraman S, Clark RSB, Horvat CM.

JAMA Netw Open. 2019 Aug 2;2(8):e199812. doi: 10.1001/jamanetworkopen.2019.9812.


Development and Performance of Electronic Pediatric Risk of Mortality and Pediatric Logistic Organ Dysfunction-2 Automated Acuity Scores.

Horvat CM, Ogoe H, Kantawala S, Au AK, Fink EL, Yablonsky E, Kochanek PM, Suresh S, Clark RSB.

Pediatr Crit Care Med. 2019 Aug;20(8):e372-e379. doi: 10.1097/PCC.0000000000001998.


Opioid e-prescribing trends at discharge in a large pediatric health system.

Horvat CM, Martin B, Wu L, Fabio A, Empey PE, Hagos F, Bigelow S, Kantawala S, Au AK, Kochanek PM, Clark RSB.

J Opioid Manag. 2019 Mar/Apr;15(2):119-127. doi: 10.5055/jom.2019.0493.


Variability in Vital Sign Documentation As a Barrier to Modeling Patient State: Why Patient Records May Need More Complexity!

Horvat CM, Ogoe H.

Pediatr Crit Care Med. 2019 Jul;20(7):690-691. doi: 10.1097/PCC.0000000000001993. No abstract available.


Factors Contributing to Fentanyl Pharmacokinetic Variability Among Diagnostically Diverse Critically Ill Children.

Hagos FT, Horvat CM, Au AK, Conley YP, Li L, Poloyac SM, Kochanek PM, Clark RSB, Empey PE.

Clin Pharmacokinet. 2019 Dec;58(12):1567-1576. doi: 10.1007/s40262-019-00773-1.


Get Ready for Another HIT: Health Information Technology and Information Transparency.

Horvat CM, Bart R.

Pediatr Crit Care Med. 2019 May;20(5):492-493. doi: 10.1097/PCC.0000000000001914. No abstract available.


Why do we give "orphan" approval to biologic therapies but not to extracorporeal blood purification therapies for hyperinflammatory syndromes?

Horvat CM, Carcillo JA.

Minerva Anestesiol. 2019 May;85(5):465-467. doi: 10.23736/S0375-9393.19.13711-X. No abstract available.


C-Reactive Protein and Ferritin Are Associated With Organ Dysfunction and Mortality in Hospitalized Children.

Horvat CM, Bell J, Kantawala S, Au AK, Clark RSB, Carcillo JA.

Clin Pediatr (Phila). 2019 Jun;58(7):752-760. doi: 10.1177/0009922819837352. Epub 2019 Mar 31.


Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications.

Hagos FT, Adams SM, Poloyac SM, Kochanek PM, Horvat CM, Clark RSB, Empey PE.

Exp Neurol. 2019 Jul;317:10-21. doi: 10.1016/j.expneurol.2019.02.011. Epub 2019 Feb 21. Review.


Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision.

Kochanek PM, Jackson TC, Jha RM, Clark RSB, Okonkwo DO, Bayır H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, Puccio AM, Horvat CM, Au AK, Elmer J, Treble-Barna A, Ikonomovic MD, Shutter LA, Taylor DL, Stern AM, Graham SH, Kagan VE, Jackson EK, Wisniewski SR, Dixon CE.

J Neurotrauma. 2019 Feb 1. doi: 10.1089/neu.2018.6203. [Epub ahead of print]


Hertz So Good: Bedside Ultrasound Implementation by Pediatric Critical Care Training Programs.

Kaselitz T, Schott C, Horvat CM.

Pediatr Crit Care Med. 2018 Nov;19(11):1091-1092. doi: 10.1097/PCC.0000000000001716. No abstract available.


A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance.

Huttner IG, Wang LW, Santiago CF, Horvat C, Johnson R, Cheng D, von Frieling-Salewsky M, Hillcoat K, Bemand TJ, Trivedi G, Braet F, Hesselson D, Alford K, Hayward CS, Seidman JG, Seidman CE, Feneley MP, Linke WA, Fatkin D.

Circ Genom Precis Med. 2018 Aug;11(8):e002135. doi: 10.1161/CIRCGEN.118.002135.


Response to Brodehl et al.

Minoche AE, Horvat C, Johnson R, Gayevskiy V, Morton SU, Drew AP, Woo K, Statham AL, Lundie B, Bagnall RD, Ingles J, Semsarian C, Seidman JG, Seidman CE, Dinger ME, Cowley MJ, Fatkin D.

Genet Med. 2019 May;21(5):1248-1249. doi: 10.1038/s41436-018-0292-1. Epub 2018 Sep 28. No abstract available.


The path to great pediatric septic shock outcomes.

Ames SG, Horvat CM, Zaritsky A, Carcillo JA.

Crit Care. 2018 Sep 22;22(1):224. doi: 10.1186/s13054-018-2147-1. No abstract available.


Presenting Characteristics Associated With Outcome in Children With Severe Traumatic Brain Injury: A Secondary Analysis From a Randomized, Controlled Trial of Therapeutic Hypothermia.

Rosario BL, Horvat CM, Wisniewski SR, Bell MJ, Panigrahy A, Zuccoli G, Narayanan S, Balasubramani GK, Beers SR, Adelson PD; Investigators of the Cool Kids Trial.

Pediatr Crit Care Med. 2018 Oct;19(10):957-964. doi: 10.1097/PCC.0000000000001676.


Contrast-Enhanced Ultrasonography During Extracorporeal Membrane Oxygenation.

Squires JH, Alcamo AM, Horvat C, Sharma MS.

J Ultrasound Med. 2019 Feb;38(2):545-548. doi: 10.1002/jum.14710. Epub 2018 Jul 29. No abstract available.


Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy.

Minoche AE, Horvat C, Johnson R, Gayevskiy V, Morton SU, Drew AP, Woo K, Statham AL, Lundie B, Bagnall RD, Ingles J, Semsarian C, Seidman JG, Seidman CE, Dinger ME, Cowley MJ, Fatkin D.

Genet Med. 2019 Mar;21(3):650-662. doi: 10.1038/s41436-018-0084-7. Epub 2018 Jul 2.


A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy.

Horvat C, Johnson R, Lam L, Munro J, Mazzarotto F, Roberts AM, Herman DS, Parfenov M, Haghighi A, McDonough B, DePalma SR, Keogh AM, Macdonald PS, Hayward CS, Roberts A, Barton PJR, Felkin LE, Giannoulatou E, Cook SA, Seidman JG, Seidman CE, Fatkin D.

Genet Med. 2019 Jan;21(1):133-143. doi: 10.1038/s41436-018-0036-2. Epub 2018 Jun 11.


A Computable Definition of Sepsis Facilitates Screening and Performance Improvement Tracking.

Alessi LJ, Warmus HR, Schaffner EK, Kantawala S, Carcillo J, Rosen J, Horvat CM.

Pediatr Qual Saf. 2018 Mar;3(2):e067. doi: 10.1097/pq9.0000000000000067. Epub 2018 Apr 10.


Rapid increase in atmospheric iodine levels in the North Atlantic since the mid-20th century.

Cuevas CA, Maffezzoli N, Corella JP, Spolaor A, Vallelonga P, Kjær HA, Simonsen M, Winstrup M, Vinther B, Horvat C, Fernandez RP, Kinnison D, Lamarque JF, Barbante C, Saiz-Lopez A.

Nat Commun. 2018 Apr 13;9(1):1452. doi: 10.1038/s41467-018-03756-1.


Timing Matters But Is Not Everything: Gauging the Influence of Technology on Nurse and Orderly Work.

Butler G, Horvat CM.

Pediatr Crit Care Med. 2018 Apr;19(4):381-382. doi: 10.1097/PCC.0000000000001452. No abstract available.


Presenting predictors and temporal trends of treatment-related outcomes in diabetic ketoacidosis.

Horvat CM, Ismail HM, Au AK, Garibaldi L, Siripong N, Kantawala S, Aneja RK, Hupp DS, Kochanek PM, Clark RS.

Pediatr Diabetes. 2018 Aug;19(5):985-992. doi: 10.1111/pedi.12663. Epub 2018 Apr 26.


Healthcare in the PICU May Be More Complicated Than We Thought-Who Knew?

Horvat CM, Clark RSB.

Pediatr Crit Care Med. 2017 Dec;18(12):1188-1189. doi: 10.1097/PCC.0000000000001356. No abstract available.


Big Data Not Yet Big Enough to Determine the Influence of Intracranial Pressure Monitoring on Outcome in Children With Severe Traumatic Brain Injury.

Horvat CM, Kochanek PM.

JAMA Pediatr. 2017 Oct 1;171(10):942-943. doi: 10.1001/jamapediatrics.2017.2390. No abstract available.


Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children.

Clark RSB, Empey PE, Bayır H, Rosario BL, Poloyac SM, Kochanek PM, Nolin TD, Au AK, Horvat CM, Wisniewski SR, Bell MJ.

PLoS One. 2017 Jul 7;12(7):e0180280. doi: 10.1371/journal.pone.0180280. eCollection 2017.


The frequency and extent of sub-ice phytoplankton blooms in the Arctic Ocean.

Horvat C, Jones DR, Iams S, Schroeder D, Flocco D, Feltham D.

Sci Adv. 2017 Mar 29;3(3):e1601191. doi: 10.1126/sciadv.1601191. eCollection 2017 Mar.


ABCB1 genotype is associated with fentanyl requirements in critically ill children.

Horvat CM, Au AK, Conley YP, Kochanek PM, Li L, Poloyac SM, Empey PE, Clark RSB.

Pediatr Res. 2017 Jul;82(1):29-35. doi: 10.1038/pr.2017.103. Epub 2017 May 31.


Management of the Pediatric Neurocritical Care Patient.

Horvat CM, Mtaweh H, Bell MJ.

Semin Neurol. 2016 Dec;36(6):492-501. Epub 2016 Dec 1. Review.


The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size.

Christensen AH, Chatelain FC, Huttner IG, Olesen MS, Soka M, Feliciangeli S, Horvat C, Santiago CF, Vandenberg JI, Schmitt N, Olesen SP, Lesage F, Fatkin D.

J Mol Cell Cardiol. 2016 Aug;97:24-35. doi: 10.1016/j.yjmcc.2016.04.006. Epub 2016 Apr 19.


Bringing attention into higher focus within the traumatic brain injury research agenda.

Horvat CM, Bell MJ.

Transl Pediatr. 2015 Oct;4(4):320-2. doi: 10.3978/j.issn.2224-4336.2015.10.05. No abstract available.


Searching for the Brain's Canary in the Coal Mine.

Horvat CM, Fink EL.

Crit Care Med. 2015 Oct;43(10):2265-6. doi: 10.1097/CCM.0000000000001267. No abstract available.


Liquid fluorocarbon lavage to clear thrombus from the distal airways after severe pulmonary hemorrhage requiring extracorporeal life support (ECLS).

Horvat CM, Carcillo JA, Dezfulian C.

Respir Med Case Rep. 2015 Mar 11;15:7-8. doi: 10.1016/j.rmcr.2015.02.010. eCollection 2015.


Evaluation of Electronic Medical Record Vital Sign Data Versus a Commercially Available Acuity Score in Predicting Need for Critical Intervention at a Tertiary Children's Hospital.

da Silva YS, Hamilton MF, Horvat C, Fink EL, Palmer F, Nowalk AJ, Winger DG, Clark RS.

Pediatr Crit Care Med. 2015 Sep;16(7):644-51. doi: 10.1097/PCC.0000000000000444.


Thiamin Deficiency as a Cause of Persistent Hyperlactatemia in a Parenteral Nutrition-Dependent Patient.

Da Silva YS, Horvat CM, Dezfulian C.

JPEN J Parenter Enteral Nutr. 2015 Jul;39(5):604-6. doi: 10.1177/0148607114545128. Epub 2014 Aug 5.


Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A.

Prosser GA, Copp JN, Mowday AM, Guise CP, Syddall SP, Williams EM, Horvat CN, Swe PM, Ashoorzadeh A, Denny WA, Smaill JB, Patterson AV, Ackerley DF.

Biochem Pharmacol. 2013 Apr 15;85(8):1091-103. doi: 10.1016/j.bcp.2013.01.029. Epub 2013 Feb 8.


A Comparative Study of Embedded and Anesthetized Zebrafish in vivo on Myocardiac Calcium Oscillation and Heart Muscle Contraction.

Muntean BS, Horvat CM, Behler JH, Aboualaiwi WA, Nauli AM, Williams FE, Nauli SM.

Front Pharmacol. 2010 Dec 6;1:139. doi: 10.3389/fphar.2010.00139. eCollection 2010.


A persistent pesticide residue and the unusual catalytic proficiency of a dehalogenating enzyme.

Horvat CM, Wolfenden RV.

Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16199-202. Epub 2005 Oct 31.

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