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Items: 1 to 50 of 1654

1.

Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a de novo DNA Methyltransferase.

Jiang Z, Lai Y, Beaver JM, Tsegay PS, Zhao ML, Horton JK, Zamora M, Rein HL, Miralles F, Shaver M, Hutcheson JD, Agoulnik I, Wilson SH, Liu Y.

Cells. 2020 Jan 16;9(1). pii: E225. doi: 10.3390/cells9010225.

2.
3.

On slow medicine: Med Life with Dr. Horton.

Horton J.

CMAJ. 2020 Jan 13;192(2):E50. doi: 10.1503/cmaj.191711. No abstract available.

PMID:
31932346
4.

An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.

Dai S, Horton JR, Wilkinson AW, Gozani O, Zhang X, Cheng X.

J Biol Chem. 2020 Jan 7. pii: jbc.RA119.012319. doi: 10.1074/jbc.RA119.012319. [Epub ahead of print]

5.

Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 Å.

Horton JR, Yang J, Zhang X, Petronzio T, Fomenkov A, Wilson GG, Roberts RJ, Cheng X.

Nucleic Acids Res. 2019 Dec 27. pii: gkz1195. doi: 10.1093/nar/gkz1195. [Epub ahead of print]

PMID:
31879785
6.

Modelling flexible protein-ligand binding in p38α MAP kinase using the QUBE force field.

Horton JT, Allen AEA, Cole DJ.

Chem Commun (Camb). 2020 Jan 18;56(6):932-935. doi: 10.1039/c9cc08574b. Epub 2019 Dec 18.

PMID:
31850454
7.

On patient-centred care at the end of life: Med Life with Dr. Horton.

Horton J.

CMAJ. 2019 Dec 16;191(50):E1393. doi: 10.1503/cmaj.191590. No abstract available.

PMID:
31844029
8.

Higher frequency of vertebrate-infecting viruses in the gut of infants born to mothers with type 1 diabetes.

Kim KW, Allen DW, Briese T, Couper JJ, Barry SC, Colman PG, Cotterill AM, Davis EA, Giles LC, Harrison LC, Harris M, Haynes A, Horton JL, Isaacs SR, Jain K, Lipkin WI, McGorm K, Morahan G, Morbey C, Pang ICN, Papenfuss AT, Penno MAS, Sinnott RO, Soldatos G, Thomson RL, Vuillermin P, Wentworth JM, Wilkins MR, Rawlinson WD, Craig ME; ENDIA STUDY GROUP.

Pediatr Diabetes. 2019 Dec 4. doi: 10.1111/pedi.12952. [Epub ahead of print]

PMID:
31800147
9.

Cohort profile: HealthWise Wales. A research register and population health data platform with linkage to National Health Service data sets in Wales.

Hurt L, Ashfield-Watt P, Townson J, Heslop L, Copeland L, Atkinson MD, Horton J, Paranjothy S.

BMJ Open. 2019 Dec 2;9(12):e031705. doi: 10.1136/bmjopen-2019-031705.

10.

Shining light on the response to repair intermediates in DNA of living cells.

Janoshazi AK, Horton JK, Zhao ML, Prasad R, Scappini EL, Tucker CJ, Wilson SH.

DNA Repair (Amst). 2020 Jan;85:102749. doi: 10.1016/j.dnarep.2019.102749. Epub 2019 Nov 12.

PMID:
31790865
11.

Publishing trends in velopharyngeal insufficiency.

Poff C, Horton J, Boerner R, Marston AP, Nguyen SA, White DR.

Int J Pediatr Otorhinolaryngol. 2020 Feb;129:109761. doi: 10.1016/j.ijporl.2019.109761. Epub 2019 Oct 31.

PMID:
31760335
12.

Intracardiac administration of ephrinA1-Fc preserves mitochondrial bioenergetics during acute ischemia/reperfusion injury.

Torres MJ, McLaughlin KL, Renegar RH, Valsaraj S, Whitehurst KS, Sharaf OM, Sharma UM, Horton JL, Sarathy B, Parks JC, Brault JJ, Fisher-Wellman KH, Neufer PD, Virag JAI.

Life Sci. 2019 Dec 15;239:117053. doi: 10.1016/j.lfs.2019.117053. Epub 2019 Nov 13.

PMID:
31733316
13.

On joy in medicine: Med Life with Dr. Horton.

Horton J.

CMAJ. 2019 Nov 11;191(45):E1259. doi: 10.1503/cmaj.191400. No abstract available.

PMID:
31712366
14.

Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne.

Wu X, Liu S, Sagum C, Chen J, Singh R, Chaturvedi A, Horton JR, Kashyap TR, Fushman D, Cheng X, Bedford MT, Wang B.

Genes Dev. 2019 Dec 1;33(23-24):1702-1717. doi: 10.1101/gad.332395.119. Epub 2019 Nov 7.

PMID:
31699778
15.

Canine and Equine Therapy for Mental Health: A Review of Clinical Effectiveness [Internet].

Young C, Horton J.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 Aug 30.

16.
17.

On mindfulness practice: Med Life with Dr. Horton.

Horton J.

CMAJ. 2019 Oct 15;191(41):E1146. doi: 10.1503/cmaj.191277. No abstract available.

PMID:
31615828
18.

The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site.

Horton JR, Woodcock CB, Opot SB, Reich NO, Zhang X, Cheng X.

Nat Commun. 2019 Oct 10;10(1):4600. doi: 10.1038/s41467-019-12498-7.

19.

The future of force fields in computer-aided drug design.

Cole DJ, Horton JT, Nelson L, Kurdekar V.

Future Med Chem. 2019 Sep;11(18):2359-2363. doi: 10.4155/fmc-2019-0196. Epub 2019 Sep 23. No abstract available.

20.

Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes.

Zoeller EL, Pedro B, Konen J, Dwivedi B, Rupji M, Sundararaman N, Wang L, Horton JR, Zhong C, Barwick BG, Cheng X, Martinez ED, Torres MP, Kowalski J, Marcus AI, Vertino PM.

J Cell Sci. 2019 Oct 9;132(19). pii: jcs231514. doi: 10.1242/jcs.231514.

PMID:
31515279
21.

On mentorship: Med Life with Dr. Horton.

Horton J.

CMAJ. 2019 Sep 9;191(36):E1016. doi: 10.1503/cmaj.191119. No abstract available.

PMID:
31501190
22.

Water-Soluble Sulfonate Schiff-Base Ligands as Fluorescent Detectors for Metal Ions in Drinking Water and Biological Systems.

Reimann MJ, Salmon DR, Horton JT, Gier EC, Jefferies LR.

ACS Omega. 2019 Feb 8;4(2):2874-2882. doi: 10.1021/acsomega.8b02750. eCollection 2019 Feb 28.

23.

Automatic Planning of Whole Breast Radiation Therapy Using Machine Learning Models.

Sheng Y, Li T, Yoo S, Yin FF, Blitzblau R, Horton JK, Ge Y, Wu QJ.

Front Oncol. 2019 Aug 7;9:750. doi: 10.3389/fonc.2019.00750. eCollection 2019.

24.

Histone H3 Lysine 56 Acetylation Enhances AP Endonuclease 1-Mediated Repair of AP Sites in Nucleosome Core Particles.

Rodriguez Y, Horton JK, Wilson SH.

Biochemistry. 2019 Sep 3;58(35):3646-3655. doi: 10.1021/acs.biochem.9b00433. Epub 2019 Aug 16.

PMID:
31407575
25.

On burnout and physician well-being: Med Life with Dr. Horton.

Horton J.

CMAJ. 2019 Aug 12;191(32):E906. doi: 10.1503/cmaj.190852. No abstract available.

PMID:
31405844
26.

Preliminary Analysis From the Craniofacial Collaboration United Kingdom Developmental Outcomes in Children With Sagittal Synostosis.

Care H, Kennedy-Williams P, Cunliffe A, Denly S, Horton J, Kearney A, Knapp M, O'Leary G, Piggott K, Pinckston M, Rooney N, Thomas S, Dalton L.

J Craniofac Surg. 2019 Sep;30(6):1740-1744. doi: 10.1097/SCS.0000000000005575.

PMID:
31403506
27.

Structural basis for the target specificity of actin histidine methyltransferase SETD3.

Dai S, Horton JR, Woodcock CB, Wilkinson AW, Zhang X, Gozani O, Cheng X.

Nat Commun. 2019 Aug 6;10(1):3541. doi: 10.1038/s41467-019-11554-6.

28.

Carotid-cochlear dehiscence: a dangerous mimicker of inner ear pathologies.

Koochakzadeh S, Dornhoffer JR, Horton JD, Meyer TA.

BMJ Case Rep. 2019 Jul 17;12(7). pii: e229773. doi: 10.1136/bcr-2019-229773.

PMID:
31320373
29.

Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis.

Horton J, Sterrenburg M, Lane S, Maheshwari A, Li TC, Cheong Y.

Hum Reprod Update. 2019 Sep 11;25(5):592-632. doi: 10.1093/humupd/dmz012.

PMID:
31318420
30.

SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1.

Crewe C, Zhu Y, Paschoal VA, Joffin N, Ghaben AL, Gordillo R, Oh DY, Liang G, Horton JD, Scherer PE.

JCI Insight. 2019 Jul 16;5. pii: 129397. doi: 10.1172/jci.insight.129397.

31.

Predictors of Bowel Resection During Nonelective Ladd Procedure for Pediatric Malrotation.

Do WS, Marenco CW, Horton JD, Escobar MA Jr.

J Surg Res. 2019 Nov;243:419-426. doi: 10.1016/j.jss.2019.05.052. Epub 2019 Jul 3.

PMID:
31279268
32.

Structural basis of specific DNA binding by the transcription factor ZBTB24.

Ren R, Hardikar S, Horton JR, Lu Y, Zeng Y, Singh AK, Lin K, Coletta LD, Shen J, Lin Kong CS, Hashimoto H, Zhang X, Chen T, Cheng X.

Nucleic Acids Res. 2019 Sep 19;47(16):8388-8398. doi: 10.1093/nar/gkz557.

33.

Eukaryotic Base Excision Repair: New Approaches Shine Light on Mechanism.

Beard WA, Horton JK, Prasad R, Wilson SH.

Annu Rev Biochem. 2019 Jun 20;88:137-162. doi: 10.1146/annurev-biochem-013118-111315.

PMID:
31220977
34.

Early Changes in Cement-Bone Fixation Using a Novel Rat Knee Replacement Model.

Mann KA, Miller MA, Amendola RL, Cyndari KI, Horton JA, Damron TA, Oest ME.

J Orthop Res. 2019 Oct;37(10):2163-2171. doi: 10.1002/jor.24390. Epub 2019 Jul 8.

PMID:
31206747
35.

Transcatheter embolization of systemic-to-pulmonary artery fistulas in a dog using embolization coils and silk suture.

Winter RL, Horton JA, Newhard DK, Holland M.

J Vet Cardiol. 2019 Jun;23:104-111. doi: 10.1016/j.jvc.2019.02.003. Epub 2019 Mar 23.

PMID:
31174720
36.

Variable osteogenic performance of MC3T3-E1 subclones impacts their utility as models of osteoblast biology.

Hwang PW, Horton JA.

Sci Rep. 2019 Jun 5;9(1):8299. doi: 10.1038/s41598-019-44575-8.

37.

Youth Growing Up in Families Experiencing Parental Substance Use Disorders and Homelessness: A High-Risk Population.

Ijadi-Maghsoodi R, Quan M, Horton J, Ryan GW, Kataoka S, Lester P, Milburn NG, Gelberg L.

J Child Adolesc Psychopharmacol. 2019 Dec;29(10):773-782. doi: 10.1089/cap.2019.0011. Epub 2019 May 16.

PMID:
31094577
38.

Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.

Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X.

Nucleic Acids Res. 2019 Sep 19;47(16):8375-8387. doi: 10.1093/nar/gkz381.

39.

Evaluation of the Effect of Morphine and Imiquimodon Expression of TLR2 and TLR4 from Lesion RNA Extracted from BALB/c Mice Infected with Leishmania major.

Ebrahimisadr P, Ghaffarifar F, Horton J, Dalimi A, Sharifi Z.

Avicenna J Med Biotechnol. 2019 Apr-Jun;11(2):202-205.

40.

Air Bubbles Introduced From Peripheral Intravenous Lines Into the Cerebral Venous System.

Horton JC.

J Neuroophthalmol. 2019 Sep;39(3):437. doi: 10.1097/WNO.0000000000000784. No abstract available.

PMID:
31022062
41.

Realist evaluation of cancer rehabilitation services in South Wales (REEACaRS): a mixed methods study protocol.

Csontos JK, Fitzsimmons D, Jones M, Wilkinson WM, Horton J, Love-Gould L, Tee A, Watts T.

BMJ Open. 2019 Apr 23;9(4):e025953. doi: 10.1136/bmjopen-2018-025953.

42.

Lessons Learned From Hurricane Maria in Puerto Rico: Practical Measures to Mitigate the Impact of a Catastrophic Natural Disaster on Radiation Oncology Patients.

Gay HA, Santiago R, Gil B, Remedios C, Montes PJ, López-Araujo J, Chévere CM, Imbert WS, White J, Arthur DW, Horton JK, Jagsi R, Rabinovich R, Beriwal S, Viswanathan A, Erickson BA, Rengan R, Palma D, Loo BW Jr, Kavanaugh JA, Bradley J, Yom SS, Harari PM, Lee Burnett O 3rd.

Pract Radiat Oncol. 2019 Sep - Oct;9(5):305-321. doi: 10.1016/j.prro.2019.03.007. Epub 2019 Apr 15.

43.

N-heterocyclic carbene-functionalized magic-number gold nanoclusters.

Narouz MR, Osten KM, Unsworth PJ, Man RWY, Salorinne K, Takano S, Tomihara R, Kaappa S, Malola S, Dinh CT, Padmos JD, Ayoo K, Garrett PJ, Nambo M, Horton JH, Sargent EH, Häkkinen H, Tsukuda T, Crudden CM.

Nat Chem. 2019 May;11(5):419-425. doi: 10.1038/s41557-019-0246-5. Epub 2019 Apr 15.

PMID:
30988416
44.

Immune Evasion by Head and Neck Cancer: Foundations for Combination Therapy.

Horton JD, Knochelmann HM, Day TA, Paulos CM, Neskey DM.

Trends Cancer. 2019 Apr;5(4):208-232. doi: 10.1016/j.trecan.2019.02.007. Epub 2019 Mar 20. Review.

PMID:
30961829
45.

Papilledema from gain-of-function mutations in the STAT3 gene.

Suh YW, Horton JC.

Ophthalmic Genet. 2019 Apr;40(2):165-169. doi: 10.1080/13816810.2019.1592202. Epub 2019 Apr 3.

PMID:
30942636
46.

Use of Multifactorial Treatments to Address the Challenge of Translating Experimental Myocardial Infarct Reduction Strategies.

Horton JL, Virag J.

Int J Mol Sci. 2019 Mar 22;20(6). pii: E1449. doi: 10.3390/ijms20061449. Review.

47.

Response to "Confounding factors for opioid prescription after common pediatric surgeries".

Horton JD, White DR, Cina RA.

J Pediatr Surg. 2019 Jul;54(7):1514. doi: 10.1016/j.jpedsurg.2019.02.024. Epub 2019 Feb 28. No abstract available.

PMID:
30879745
48.

Specialty-specific reduction in opioid prescribing after common pediatric surgical operations.

Horton JD, Munawar S, Feuvrier A, Corrigan C, Lockett M, White D, Cina RA.

J Pediatr Surg. 2019 Oct;54(10):1984-1987. doi: 10.1016/j.jpedsurg.2019.02.008. Epub 2019 Feb 28.

PMID:
30879744
49.

Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study.

Wook Kim K, Allen DW, Briese T, Couper JJ, Barry SC, Colman PG, Cotterill AM, Davis EA, Giles LC, Harrison LC, Harris M, Haynes A, Horton JL, Isaacs SR, Jain K, Lipkin WI, Morahan G, Morbey C, Pang ICN, Papenfuss AT, Penno MAS, Sinnott RO, Soldatos G, Thomson RL, Vuillermin PJ, Wentworth JM, Wilkins MR, Rawlinson WD, Craig ME; ENDIA Study Group.

Open Forum Infect Dis. 2019 Jan 16;6(2):ofz025. doi: 10.1093/ofid/ofz025. eCollection 2019 Feb.

50.

Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure.

Milite C, Feoli A, Horton JR, Rescigno D, Cipriano A, Pisapia V, Viviano M, Pepe G, Amendola G, Novellino E, Cosconati S, Cheng X, Castellano S, Sbardella G.

J Med Chem. 2019 Mar 14;62(5):2666-2689. doi: 10.1021/acs.jmedchem.8b02008. Epub 2019 Feb 26.

PMID:
30753076

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