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Back from the dead: TIL apoptosis in cancer immune evasion.

Horton BL, Gajewski TF.

Br J Cancer. 2018 Feb 6;118(3):309-311. doi: 10.1038/bjc.2017.483. Epub 2018 Jan 23. No abstract available.


Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity.

Horton BL, Williams JB, Cabanov A, Spranger S, Gajewski TF.

Cancer Immunol Res. 2018 Jan;6(1):14-24. doi: 10.1158/2326-6066.CIR-17-0249. Epub 2017 Nov 2.


The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment.

Williams JB, Horton BL, Zheng Y, Duan Y, Powell JD, Gajewski TF.

J Exp Med. 2017 Feb;214(2):381-400. doi: 10.1084/jem.20160485. Epub 2017 Jan 23.

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