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Items: 17

1.

Insulin-induced translocation of IR to the nucleus in insulin responsive cells requires a nuclear translocation sequence.

Kesten D, Horovitz-Fried M, Brutman-Barazani T, Sampson SR.

Biochim Biophys Acta Mol Cell Res. 2018 Apr;1865(4):551-559. doi: 10.1016/j.bbamcr.2018.01.004. Epub 2018 Jan 6.

2.

The mutational status of p53 can influence its recognition by human T-cells.

Shamalov K, Levy SN, Horovitz-Fried M, Cohen CJ.

Oncoimmunology. 2017 Jan 31;6(4):e1285990. doi: 10.1080/2162402X.2017.1285990. eCollection 2017.

3.

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes.

Cohen CJ, Gartner JJ, Horovitz-Fried M, Shamalov K, Trebska-McGowan K, Bliskovsky VV, Parkhurst MR, Ankri C, Prickett TD, Crystal JS, Li YF, El-Gamil M, Rosenberg SA, Robbins PF.

J Clin Invest. 2015 Oct 1;125(10):3981-91. doi: 10.1172/JCI82416. Epub 2015 Sep 21.

4.

Nanomedicine for Cancer Immunotherapy: Tracking Cancer-Specific T-Cells in Vivo with Gold Nanoparticles and CT Imaging.

Meir R, Shamalov K, Betzer O, Motiei M, Horovitz-Fried M, Yehuda R, Popovtzer A, Popovtzer R, Cohen CJ.

ACS Nano. 2015 Jun 23;9(6):6363-72. doi: 10.1021/acsnano.5b01939. Epub 2015 Jun 11.

PMID:
26039633
5.

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities.

Tal Y, Yaakobi S, Horovitz-Fried M, Safyon E, Rosental B, Porgador A, Cohen CJ.

Oncotarget. 2014 Nov 15;5(21):10949-58.

6.

Human T cells engineered to express a programmed death 1/28 costimulatory retargeting molecule display enhanced antitumor activity.

Ankri C, Shamalov K, Horovitz-Fried M, Mauer S, Cohen CJ.

J Immunol. 2013 Oct 15;191(8):4121-9. doi: 10.4049/jimmunol.1203085. Epub 2013 Sep 11.

7.

Enhanced antitumor activity mediated by human 4-1BB-engineered T cells.

Daniel-Meshulam I, Horovitz-Fried M, Cohen CJ.

Int J Cancer. 2013 Dec 15;133(12):2903-13. doi: 10.1002/ijc.28320. Epub 2013 Jul 16.

8.

Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity.

Haga-Friedman A, Horovitz-Fried M, Cohen CJ.

J Immunol. 2012 Jun 1;188(11):5538-46. doi: 10.4049/jimmunol.1103020. Epub 2012 Apr 27.

9.

Protein kinase Cδ but not PKCα is involved in insulin-induced glucose metabolism in hepatocytes.

Brutman-Barazani T, Horovitz-Fried M, Aga-Mizrachi S, Brand C, Brodie C, Rosa J, Sampson SR.

J Cell Biochem. 2012 Jun;113(6):2064-76. doi: 10.1002/jcb.24078.

PMID:
22271577
10.

Insulin stimulation of PKCδ triggers its rapid degradation via the ubiquitin-proteasome pathway.

Brand C, Horovitz-Fried M, Inbar A, Tamar-Brutman-Barazani, Brodie C, Sampson SR.

Biochim Biophys Acta. 2010 Nov;1803(11):1265-75. doi: 10.1016/j.bbamcr.2010.07.006. Epub 2010 Aug 12.

11.

Insulin increases H2O2-induced pancreatic beta cell death.

Sampson SR, Bucris E, Horovitz-Fried M, Parnas A, Kahana S, Abitbol G, Chetboun M, Rosenzweig T, Brodie C, Frankel S.

Apoptosis. 2010 Oct;15(10):1165-76. doi: 10.1007/s10495-010-0517-5.

PMID:
20544287
12.

Selected murine residues endow human TCR with enhanced tumor recognition.

Bialer G, Horovitz-Fried M, Ya'acobi S, Morgan RA, Cohen CJ.

J Immunol. 2010 Jun 1;184(11):6232-41. doi: 10.4049/jimmunol.0902047. Epub 2010 Apr 28.

13.

The regulatory domain of protein kinase C delta positively regulates insulin receptor signaling.

Jacob AI, Horovitz-Fried M, Aga-Mizrachi S, Brutman-Barazani T, Okhrimenko H, Zick Y, Brodie C, Sampson SR.

J Mol Endocrinol. 2010 Mar;44(3):155-69. doi: 10.1677/JME-09-0119. Epub 2009 Dec 1.

PMID:
19952103
14.

Insulin increases nuclear protein kinase Cdelta in L6 skeletal muscle cells.

Horovitz-Fried M, Brutman-Barazani T, Kesten D, Sampson SR.

Endocrinology. 2008 Apr;149(4):1718-27. Epub 2007 Dec 27.

PMID:
18162512
15.

Involvement of PKCalpha in insulin-induced PKCdelta expression: Importance of SP-1 and NFkappaB transcription factors.

Horovitz-Fried M, Sampson SR.

Biochem Biophys Res Commun. 2007 Jan 5;352(1):78-83. Epub 2006 Nov 3.

PMID:
17109817
16.

Activation of the nuclear transcription factor SP-1 by insulin rapidly increases the expression of protein kinase C delta in skeletal muscle.

Horovitz-Fried M, Jacob AI, Cooper DR, Sampson SR.

Cell Signal. 2007 Mar;19(3):556-62. Epub 2006 Aug 23.

PMID:
17046201
17.

Insulin rapidly upregulates protein kinase Cdelta gene expression in skeletal muscle.

Horovitz-Fried M, Cooper DR, Patel NA, Cipok M, Brand C, Bak A, Inbar A, Jacob AI, Sampson SR.

Cell Signal. 2006 Feb;18(2):183-93. Epub 2005 Aug 10.

PMID:
16095881

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