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Items: 9


Assessment of Functional Phosphatidylinositol 3-Kinase Pathway Activity in Cancer Tissue Using Forkhead Box-O Target Gene Expression in a Knowledge-Based Computational Model.

van Ooijen H, Hornsveld M, Dam-de Veen C, Velter R, Dou M, Verhaegh W, Burgering B, van de Stolpe A.

Am J Pathol. 2018 Sep;188(9):1956-1972. doi: 10.1016/j.ajpath.2018.05.020. Epub 2018 Jul 6.


FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression.

Hornsveld M, Smits LMM, Meerlo M, van Amersfoort M, Groot Koerkamp MJA, van Leenen D, Kloet DEA, Holstege FCP, Derksen PWB, Burgering BMT, Dansen TB.

Cancer Res. 2018 May 1;78(9):2356-2369. doi: 10.1158/0008-5472.CAN-17-2511. Epub 2018 Feb 12.


Re-evaluating the role of FOXOs in cancer.

Hornsveld M, Dansen TB, Derksen PW, Burgering BMT.

Semin Cancer Biol. 2018 Jun;50:90-100. doi: 10.1016/j.semcancer.2017.11.017. Epub 2017 Nov 21. Review.


Interplay between metabolic identities in the intestinal crypt supports stem cell function.

Rodríguez-Colman MJ, Schewe M, Meerlo M, Stigter E, Gerrits J, Pras-Raves M, Sacchetti A, Hornsveld M, Oost KC, Snippert HJ, Verhoeven-Duif N, Fodde R, Burgering BM.

Nature. 2017 Mar 16;543(7645):424-427. doi: 10.1038/nature21673. Epub 2017 Mar 8.


The Hallmarks of Cancer from a Redox Perspective.

Hornsveld M, Dansen TB.

Antioxid Redox Signal. 2016 Aug 20;25(6):300-25. doi: 10.1089/ars.2015.6580. Epub 2016 Aug 2. Review.


Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer.

Hornsveld M, Tenhagen M, van de Ven RA, Smits AM, van Triest MH, van Amersfoort M, Kloet DE, Dansen TB, Burgering BM, Derksen PW.

Cell Death Differ. 2016 Sep 1;23(9):1483-92. doi: 10.1038/cdd.2016.33. Epub 2016 Apr 1.


FOXOs support the metabolic requirements of normal and tumor cells by promoting IDH1 expression.

Charitou P, Rodriguez-Colman M, Gerrits J, van Triest M, Groot Koerkamp M, Hornsveld M, Holstege F, Verhoeven-Duif NM, Burgering BM.

EMBO Rep. 2015 Apr;16(4):456-66. doi: 10.15252/embr.201439096. Epub 2015 Feb 3.


Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells.

Moutinho-Pereira S, Stuurman N, Afonso O, Hornsveld M, Aguiar P, Goshima G, Vale RD, Maiato H.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19808-13. doi: 10.1073/pnas.1320013110. Epub 2013 Nov 19.


Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice.

Derksen PW, Braumuller TM, van der Burg E, Hornsveld M, Mesman E, Wesseling J, Krimpenfort P, Jonkers J.

Dis Model Mech. 2011 May;4(3):347-58. doi: 10.1242/dmm.006395. Epub 2011 Jan 31.

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