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Items: 8


Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice.

Cai H, Scott E, Kholghi A, Andreadi C, Rufini A, Karmokar A, Britton RG, Horner-Glister E, Greaves P, Jawad D, James M, Howells L, Ognibene T, Malfatti M, Goldring C, Kitteringham N, Walsh J, Viskaduraki M, West K, Miller A, Hemingway D, Steward WP, Gescher AJ, Brown K.

Sci Transl Med. 2015 Jul 29;7(298):298ra117. doi: 10.1126/scitranslmed.aaa7619.


Search for novel circulating cancer chemopreventive biomarkers of dietary rice bran intervention in Apc(Min) mice model of colorectal carcinogenesis, using proteomic and metabolic profiling strategies.

Norris L, Malkar A, Horner-Glister E, Hakimi A, Ng LL, Gescher AJ, Creaser C, Sale S, Jones DJ.

Mol Nutr Food Res. 2015 Sep;59(9):1827-36. doi: 10.1002/mnfr.201400818. Epub 2015 Jun 30.


Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence.

Patel KR, Andreadi C, Britton RG, Horner-Glister E, Karmokar A, Sale S, Brown VA, Brenner DE, Singh R, Steward WP, Gescher AJ, Brown K.

Sci Transl Med. 2013 Oct 2;5(205):205ra133. doi: 10.1126/scitranslmed.3005870.


Synthesis and biological evaluation of novel flavonols as potential anti-prostate cancer agents.

Britton RG, Horner-Glister E, Pomenya OA, Smith EE, Denton R, Jenkins PR, Steward WP, Brown K, Gescher A, Sale S.

Eur J Med Chem. 2012 Aug;54:952-8. doi: 10.1016/j.ejmech.2012.06.031. Epub 2012 Jun 22.


Tissue distribution and metabolism of the putative cancer chemopreventive agent 3',4',5'-trimethoxyflavonol (TMFol) in mice.

Saad SE, Jones DJ, Norris LM, Horner-Glister E, Patel KR, Britton RG, Steward WP, Gescher AJ, Brown K, Sale S.

Biomed Chromatogr. 2012 Dec;26(12):1559-66. doi: 10.1002/bmc.2732. Epub 2012 Mar 27.


Differing transcriptional responses to pulsed or continuous estradiol exposure in human umbilical vein endothelial cells.

Li J, Wang H, Johnson SM, Horner-Glister E, Thompson J, White IN, Al-Azzawi F.

J Steroid Biochem Mol Biol. 2008 Jul;111(1-2):41-9. doi: 10.1016/j.jsbmb.2007.12.015. Epub 2008 Apr 22.


Tamoxifen forms DNA adducts in human colon after administration of a single [14C]-labeled therapeutic dose.

Brown K, Tompkins EM, Boocock DJ, Martin EA, Farmer PB, Turteltaub KW, Ubick E, Hemingway D, Horner-Glister E, White IN.

Cancer Res. 2007 Jul 15;67(14):6995-7002.


Influence of oestradiol and tamoxifen on oestrogen receptors-alpha and -beta protein degradation and non-genomic signalling pathways in uterine and breast carcinoma cells.

Horner-Glister E, Maleki-Dizaji M, Guerin CJ, Johnson SM, Styles J, White IN.

J Mol Endocrinol. 2005 Dec;35(3):421-32.


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