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Items: 1 to 50 of 78

1.

The Timed Pathway to Homeostasis.

Torow N, Hornef MW.

Immunity. 2019 May 21;50(5):1127-1129. doi: 10.1016/j.immuni.2019.04.012.

PMID:
31117008
2.

Pathways of host cell exit by intracellular pathogens.

Flieger A, Frischknecht F, Häcker G, Hornef MW, Pradel G.

Microb Cell. 2018 Oct 18;5(12):525-544. doi: 10.15698/mic2018.12.659. Review.

3.

The olfactory epithelium as a port of entry in neonatal neurolisteriosis.

Pägelow D, Chhatbar C, Beineke A, Liu X, Nerlich A, van Vorst K, Rohde M, Kalinke U, Förster R, Halle S, Valentin-Weigand P, Hornef MW, Fulde M.

Nat Commun. 2018 Oct 15;9(1):4269. doi: 10.1038/s41467-018-06668-2.

4.

Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW.

Nature. 2018 Nov;563(7731):E25. doi: 10.1038/s41586-018-0507-2.

PMID:
30158704
5.

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW.

Nature. 2018 Aug;560(7719):489-493. doi: 10.1038/s41586-018-0395-5. Epub 2018 Aug 8. Erratum in: Nature. 2018 Nov;563(7731):E25.

PMID:
30089902
6.

Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia.

Robak OH, Heimesaat MM, Kruglov AA, Prepens S, Ninnemann J, Gutbier B, Reppe K, Hochrein H, Suter M, Kirschning CJ, Marathe V, Buer J, Hornef MW, Schnare M, Schneider P, Witzenrath M, Bereswill S, Steinhoff U, Suttorp N, Sander LE, Chaput C, Opitz B.

J Clin Invest. 2018 Aug 1;128(8):3535-3545. doi: 10.1172/JCI97065. Epub 2018 Jul 16.

7.

The neonatal window of opportunity-early priming for life.

Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J, Ghazal P, Hackam DJ, Marsland BJ, McCoy KD, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser JN, Wesemann DR, Hornef MW.

J Allergy Clin Immunol. 2018 Apr;141(4):1212-1214. doi: 10.1016/j.jaci.2017.11.019. Epub 2017 Dec 14. No abstract available.

8.

Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells.

Selvakumar TA, Bhushal S, Kalinke U, Wirth D, Hauser H, Köster M, Hornef MW.

Front Immunol. 2017 Oct 16;8:1302. doi: 10.3389/fimmu.2017.01302. eCollection 2017.

9.

Dextran sodium sulfate (DSS) induces necrotizing enterocolitis-like lesions in neonatal mice.

Ginzel M, Feng X, Kuebler JF, Klemann C, Yu Y, von Wasielewski R, Park JK, Hornef MW, Vieten G, Ure BM, Kaussen T, Gosemann JH, Mayer S, Suttkus A, Lacher M.

PLoS One. 2017 Aug 17;12(8):e0182732. doi: 10.1371/journal.pone.0182732. eCollection 2017.

10.

Cell Polarization and Epigenetic Status Shape the Heterogeneous Response to Type III Interferons in Intestinal Epithelial Cells.

Bhushal S, Wolfsmüller M, Selvakumar TA, Kemper L, Wirth D, Hornef MW, Hauser H, Köster M.

Front Immunol. 2017 Jun 12;8:671. doi: 10.3389/fimmu.2017.00671. eCollection 2017.

11.

CD4 T Cell Dependent Colitis Exacerbation Following Re-Exposure of Mycobacterium avium ssp. paratuberculosis.

Suwandi A, Bargen I, Pils MC, Krey M, Zur Lage S, Singh AK, Basler T, Falk CS, Seidler U, Hornef MW, Goethe R, Weiss S.

Front Cell Infect Microbiol. 2017 Mar 16;7:75. doi: 10.3389/fcimb.2017.00075. eCollection 2017.

12.

Gut Colonization by Methanogenic Archaea Is Associated with Organic Dairy Consumption in Children.

van de Pol JA, van Best N, Mbakwa CA, Thijs C, Savelkoul PH, Arts IC, Hornef MW, Mommers M, Penders J.

Front Microbiol. 2017 Mar 10;8:355. doi: 10.3389/fmicb.2017.00355. eCollection 2017.

13.

The Neonatal Window of Opportunity: Setting the Stage for Life-Long Host-Microbial Interaction and Immune Homeostasis.

Torow N, Hornef MW.

J Immunol. 2017 Jan 15;198(2):557-563. doi: 10.4049/jimmunol.1601253. Review.

14.

Corrigendum: The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.

Lagkouvardos I, Pukall R, Abt B, Foesel BU, Meier-Kolthoff JP, Kumar N, Bresciani A, Martínez I, Just S, Ziegler C, Brugiroux S, Garzetti D, Wenning M, Bui TP, Wang J, Hugenholtz F, Plugge CM, Peterson DA, Hornef MW, Baines JF, Smidt H, Walter J, Kristiansen K, Nielsen HB, Haller D, Overmann J, Stecher B, Clavel T.

Nat Microbiol. 2016 Oct 17;1(11):16219. doi: 10.1038/nmicrobiol.2016.219. No abstract available.

PMID:
27748770
15.

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.

Lagkouvardos I, Pukall R, Abt B, Foesel BU, Meier-Kolthoff JP, Kumar N, Bresciani A, Martínez I, Just S, Ziegler C, Brugiroux S, Garzetti D, Wenning M, Bui TP, Wang J, Hugenholtz F, Plugge CM, Peterson DA, Hornef MW, Baines JF, Smidt H, Walter J, Kristiansen K, Nielsen HB, Haller D, Overmann J, Stecher B, Clavel T.

Nat Microbiol. 2016 Aug 8;1(10):16131. doi: 10.1038/nmicrobiol.2016.131. Erratum in: Nat Microbiol. 2016 Oct 17;1(11):16219.

PMID:
27670113
16.

Neonatal mucosal immunology.

Torow N, Marsland BJ, Hornef MW, Gollwitzer ES.

Mucosal Immunol. 2017 Jan;10(1):5-17. doi: 10.1038/mi.2016.81. Epub 2016 Sep 21. Review.

PMID:
27649929
17.

Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine.

Nikiforou M, Jacobs EM, Kemp MW, Hornef MW, Payne MS, Saito M, Newnham JP, Janssen LE, Jobe AH, Kallapur SG, Kramer BW, Wolfs TG.

Sci Rep. 2016 Jul 14;6:29806. doi: 10.1038/srep29806.

18.

Age-Dependent Susceptibility to Enteropathogenic Escherichia coli (EPEC) Infection in Mice.

Dupont A, Sommer F, Zhang K, Repnik U, Basic M, Bleich A, Kühnel M, Bäckhed F, Litvak Y, Fulde M, Rosenshine I, Hornef MW.

PLoS Pathog. 2016 May 9;12(5):e1005616. doi: 10.1371/journal.ppat.1005616. eCollection 2016 May.

19.

The viral dsRNA analogue poly (I:C) induces necrotizing enterocolitis in neonatal mice.

Ginzel M, Yu Y, Klemann C, Feng X, von Wasielewski R, Park JK, Hornef MW, Torow N, Vieten G, Ure BM, Kuebler JF, Lacher M.

Pediatr Res. 2016 Apr;79(4):596-602. doi: 10.1038/pr.2015.261. Epub 2015 Dec 17.

PMID:
26679153
20.

On the origin of species: Factors shaping the establishment of infant's gut microbiota.

van Best N, Hornef MW, Savelkoul PH, Penders J.

Birth Defects Res C Embryo Today. 2015 Dec;105(4):240-51. doi: 10.1002/bdrc.21113. Epub 2015 Nov 26. Review.

PMID:
26607554
21.

Real friends: Faecalibacterium prausnitzii supports mucosal immune homeostasis.

Hornef MW, Pabst O.

Gut. 2016 Mar;65(3):365-7. doi: 10.1136/gutjnl-2015-310027. Epub 2015 Nov 3. No abstract available.

PMID:
26531718
22.

Transcriptional profiling of intestinal CD4(+) T cells in the neonatal and adult mice.

Torow N, Dittrich-Breiholz O, Hornef MW.

Genom Data. 2015 Jul 15;5:371-4. doi: 10.1016/j.gdata.2015.07.009. eCollection 2015 Sep.

23.

The intestinal epithelium as guardian of gut barrier integrity.

Zhang K, Hornef MW, Dupont A.

Cell Microbiol. 2015 Nov;17(11):1561-9. doi: 10.1111/cmi.12501. Epub 2015 Sep 15. Review.

PMID:
26294173
24.

Active suppression of intestinal CD4(+)TCRαβ(+) T-lymphocyte maturation during the postnatal period.

Torow N, Yu K, Hassani K, Freitag J, Schulz O, Basic M, Brennecke A, Sparwasser T, Wagner N, Bleich A, Lochner M, Weiss S, Förster R, Pabst O, Hornef MW.

Nat Commun. 2015 Jul 21;6:7725. doi: 10.1038/ncomms8725.

25.

Antimicrobial peptides and the enteric mucus layer act in concert to protect the intestinal mucosa.

Dupont A, Heinbockel L, Brandenburg K, Hornef MW.

Gut Microbes. 2014;5(6):761-5. doi: 10.4161/19490976.2014.972238.

26.

Ontogeny of intestinal epithelial innate immune responses.

Hornef MW, Fulde M.

Front Immunol. 2014 Oct 9;5:474. doi: 10.3389/fimmu.2014.00474. eCollection 2014. Review.

27.

Age-dependent enterocyte invasion and microcolony formation by Salmonella.

Zhang K, Dupont A, Torow N, Gohde F, Leschner S, Lienenklaus S, Weiss S, Brinkmann MM, Kühnel M, Hensel M, Fulde M, Hornef MW.

PLoS Pathog. 2014 Sep 11;10(9):e1004385. doi: 10.1371/journal.ppat.1004385. eCollection 2014 Sep. Erratum in: PLoS Pathog. 2014 Sep;10(9):e1004476. Gohde, Fredrik [corrected to Gohde, Frederik].

28.

TRIF signaling drives homeostatic intestinal epithelial antimicrobial peptide expression.

Stockinger S, Duerr CU, Fulde M, Dolowschiak T, Pott J, Yang I, Eibach D, Bäckhed F, Akira S, Suerbaum S, Brugman M, Hornef MW.

J Immunol. 2014 Oct 15;193(8):4223-34. doi: 10.4049/jimmunol.1302708. Epub 2014 Sep 10.

29.

Experimental colitis is exacerbated by concomitant infection with Mycobacterium avium ssp. paratuberculosis.

Suwandi A, Bargen I, Roy B, Pils MC, Krey M, Zur Lage S, Basler T, Rohde M, Falk CS, Hornef MW, Goethe R, Weiss S.

Inflamm Bowel Dis. 2014 Nov;20(11):1962-71. doi: 10.1097/MIB.0000000000000157.

PMID:
25144571
30.

Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis.

Atreya R, Bülte M, Gerlach GF, Goethe R, Hornef MW, Köhler H, Meens J, Möbius P, Roeb E, Weiss S; ZooMAP Consortium.

Int J Med Microbiol. 2014 Oct;304(7):858-67. doi: 10.1016/j.ijmm.2014.07.006. Epub 2014 Jul 25. Review.

PMID:
25128370
31.

Dedicated immunosensing of the mouse intestinal epithelium facilitated by a pair of genetically coupled lectin-like receptors.

Leibelt S, Friede ME, Rohe C, Gütle D, Rutkowski E, Weigert A, Kveberg L, Vaage JT, Hornef MW, Steinle A.

Mucosal Immunol. 2015 Mar;8(2):232-42. doi: 10.1038/mi.2014.60. Epub 2014 Jul 2.

PMID:
24985083
32.

Maturation of the enteric mucosal innate immune system during the postnatal period.

Fulde M, Hornef MW.

Immunol Rev. 2014 Jul;260(1):21-34. doi: 10.1111/imr.12190. Review.

PMID:
24942679
33.

Intestinal mucus affinity and biological activity of an orally administered antibacterial and anti-inflammatory peptide.

Dupont A, Kaconis Y, Yang I, Albers T, Woltemate S, Heinbockel L, Andersson M, Suerbaum S, Brandenburg K, Hornef MW.

Gut. 2015 Feb;64(2):222-32. doi: 10.1136/gutjnl-2014-307150. Epub 2014 May 7.

PMID:
24811998
34.

Outer ear canal infection with Rhabditis sp. nematodes in a human.

Teschner M, Würfel W, Sedlacek L, Suerbaum S, Tappe D, Hornef MW.

J Clin Microbiol. 2014 May;52(5):1793-5. doi: 10.1128/JCM.00115-14. Epub 2014 Mar 5.

35.

Interleukin-13-mediated paneth cell degranulation and antimicrobial peptide release.

Stockinger S, Albers T, Duerr CU, Ménard S, Pütsep K, Andersson M, Hornef MW.

J Innate Immun. 2014;6(4):530-41. doi: 10.1159/000357644. Epub 2014 Feb 19.

36.

Norovirus triggered microbiota-driven mucosal inflammation in interleukin 10-deficient mice.

Basic M, Keubler LM, Buettner M, Achard M, Breves G, Schröder B, Smoczek A, Jörns A, Wedekind D, Zschemisch NH, Günther C, Neumann D, Lienenklaus S, Weiss S, Hornef MW, Mähler M, Bleich A.

Inflamm Bowel Dis. 2014 Mar;20(3):431-43. doi: 10.1097/01.MIB.0000441346.86827.ed.

PMID:
24487272
37.

IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock.

Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, Weber M, Kalinke U, Hofer MJ, Hatesuer B, Schughart K, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Weber F, Hornef MW, Autenrieth IB, Bohn E.

J Immunol. 2013 Oct 1;191(7):3913-21. doi: 10.4049/jimmunol.1203305. Epub 2013 Sep 6.

38.

Generation of mouse small intestinal epithelial cell lines that allow the analysis of specific innate immune functions.

Schwerk J, Köster M, Hauser H, Rohde M, Fulde M, Hornef MW, May T.

PLoS One. 2013 Aug 5;8(8):e72700. doi: 10.1371/journal.pone.0072700. Print 2013.

39.

MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury.

Chassin C, Hempel C, Stockinger S, Dupont A, Kübler JF, Wedemeyer J, Vandewalle A, Hornef MW.

EMBO Mol Med. 2012 Dec;4(12):1308-19. doi: 10.1002/emmm.201201298. Epub 2012 Nov 9.

40.

Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility.

Pott J, Stockinger S, Torow N, Smoczek A, Lindner C, McInerney G, Bäckhed F, Baumann U, Pabst O, Bleich A, Hornef MW.

PLoS Pathog. 2012;8(5):e1002670. doi: 10.1371/journal.ppat.1002670. Epub 2012 May 3.

41.

The mammalian intestinal epithelium as integral player in the establishment and maintenance of host-microbial homeostasis.

Duerr CU, Hornef MW.

Semin Immunol. 2012 Feb;24(1):25-35. doi: 10.1016/j.smim.2011.11.002. Epub 2011 Dec 3. Review.

PMID:
22138188
42.

Between vigilance and tolerance: the immune function of the intestinal epithelium.

Chassin C, Hornef MW.

Cell Mol Life Sci. 2011 Nov;68(22):3619-21. doi: 10.1007/s00018-011-0820-5. Epub 2011 Oct 4. No abstract available.

PMID:
21968918
43.

Establishment of intestinal homeostasis during the neonatal period.

Stockinger S, Hornef MW, Chassin C.

Cell Mol Life Sci. 2011 Nov;68(22):3699-712. doi: 10.1007/s00018-011-0831-2. Epub 2011 Sep 28. Review.

PMID:
21952827
44.

IFN-lambda determines the intestinal epithelial antiviral host defense.

Pott J, Mahlakõiv T, Mordstein M, Duerr CU, Michiels T, Stockinger S, Staeheli P, Hornef MW.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7944-9. doi: 10.1073/pnas.1100552108. Epub 2011 Apr 25.

45.

Potentiation of epithelial innate host responses by intercellular communication.

Dolowschiak T, Chassin C, Ben Mkaddem S, Fuchs TM, Weiss S, Vandewalle A, Hornef MW.

PLoS Pathog. 2010 Nov 18;6(11):e1001194. doi: 10.1371/journal.ppat.1001194.

46.

Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes.

Duerr CU, Salzman NH, Dupont A, Szabo A, Normark BH, Normark S, Locksley RM, Mellroth P, Hornef MW.

Mucosal Immunol. 2011 May;4(3):325-34. doi: 10.1038/mi.2010.71. Epub 2010 Oct 27.

PMID:
20980996
47.

miR-146a mediates protective innate immune tolerance in the neonate intestine.

Chassin C, Kocur M, Pott J, Duerr CU, Gütle D, Lotz M, Hornef MW.

Cell Host Microbe. 2010 Oct 21;8(4):358-68. doi: 10.1016/j.chom.2010.09.005.

48.

Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children.

Decker E, Engelmann G, Findeisen A, Gerner P, Laass M, Ney D, Posovszky C, Hoy L, Hornef MW.

Pediatrics. 2010 Jun;125(6):e1433-40. doi: 10.1542/peds.2009-2260. Epub 2010 May 17.

PMID:
20478942
49.

O-antigen delays lipopolysaccharide recognition and impairs antibacterial host defense in murine intestinal epithelial cells.

Duerr CU, Zenk SF, Chassin C, Pott J, Gütle D, Hensel M, Hornef MW.

PLoS Pathog. 2009 Sep;5(9):e1000567. doi: 10.1371/journal.ppat.1000567. Epub 2009 Sep 4.

50.

Internalization-dependent recognition of Mycobacterium avium ssp. paratuberculosis by intestinal epithelial cells.

Pott J, Basler T, Duerr CU, Rohde M, Goethe R, Hornef MW.

Cell Microbiol. 2009 Dec;11(12):1802-15. doi: 10.1111/j.1462-5822.2009.01372.x. Epub 2009 Aug 13.

PMID:
19681906

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