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Chronic pelvic pain in women: an embedded qualitative study to evaluate the perceived benefits of the meridian balance method electro-acupuncture treatment, health consultation and National Health Service standard care.

Chong OT, Critchley HO, Horne AW, Fallon M, Haraldsdottir E.

Br J Pain. 2019 Nov;13(4):244-255. doi: 10.1177/2049463718814870. Epub 2018 Nov 21.


Intrusive imagery associated with pain.

Graham CJ, Brown SL, Vincent K, Horne AW.

BMJ. 2019 Sep 10;366:l5459. doi: 10.1136/bmj.l5459. No abstract available.


Proposal for a new ICD-11 coding classification system for endometriosis.

Whitaker LHR, Byrne D, Hummelshoj L, Missmer SA, Saraswat L, Saridogan E, Tomassetti C, Horne AW.

Eur J Obstet Gynecol Reprod Biol. 2019 Oct;241:134-135. doi: 10.1016/j.ejogrb.2019.08.015. Epub 2019 Aug 26. No abstract available.


Endometriosis and Risk of Adverse Pregnancy Outcomes.

Farland LV, Prescott J, Sasamoto N, Tobias DK, Gaskins AJ, Stuart JJ, Carusi DA, Chavarro JE, Horne AW, Rich-Edwards JW, Missmer SA.

Obstet Gynecol. 2019 Sep;134(3):527-536. doi: 10.1097/AOG.0000000000003410.


Surgical removal of superficial peritoneal endometriosis for managing women with chronic pelvic pain: time for a rethink?

Horne AW, Daniels J, Hummelshoj L, Cox E, Cooper KG.

BJOG. 2019 Nov;126(12):1414-1416. doi: 10.1111/1471-0528.15894. Epub 2019 Aug 16. No abstract available.


Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis.

Forster R, Sarginson A, Velichkova A, Hogg C, Dorning A, Horne AW, Saunders PTK, Greaves E.

FASEB J. 2019 Oct;33(10):11210-11222. doi: 10.1096/fj.201900797R. Epub 2019 Jul 10.


The use of brain functional magnetic resonance imaging to determine the mechanism of action of gabapentin in managing chronic pelvic pain in women: a pilot study.

Seretny M, Murray SR, Whitaker L, Murnane J, Whalley H, Pernet C, Horne AW.

BMJ Open. 2019 Jun 27;9(6):e026152. doi: 10.1136/bmjopen-2018-026152.


Disparity in endometriosis diagnoses between racial/ethnic groups.

Farland LV, Horne AW.

BJOG. 2019 Aug;126(9):1115-1116. doi: 10.1111/1471-0528.15805. Epub 2019 May 21. No abstract available.


A multi-centre, double-blind, placebo-controlled, randomised trial of combination methotrexate and gefitinib versus methotrexate alone to treat tubal ectopic pregnancies (GEM3): trial protocol.

May J, Duncan C, Mol B, Bhattacharya S, Daniels J, Middleton L, Hewitt C, Coomarasamy A, Jurkovic D, Bourne T, Bottomley C, Peace-Gadsby A, Doust A, Tong S, Horne AW.

Trials. 2018 Nov 20;19(1):643. doi: 10.1186/s13063-018-3008-6.


The impact of meridian balance method electro-acupuncture treatment on chronic pelvic pain in women: a three-armed randomised controlled feasibility study using a mixed-methods approach.

Chong OT, Critchley HO, Williams LJ, Haraldsdottir E, Horne AW, Fallon M.

Br J Pain. 2018 Nov;12(4):238-249. doi: 10.1177/2049463718776044. Epub 2018 May 14.


Gefitinib and Methotrexate to Treat Ectopic Pregnancies with a Pre-Treatment Serum hCG 1000-10,000 IU/L: Phase II Open Label, Single Arm Multi-Centre Trial.

Skubisz MM, Tong S, Doust A, Mollison J, Johns TG, Neil P, Robinson M, Bhattacharya S, Wallace E, Krzys N, Colin Duncan W, Horne AW.

EBioMedicine. 2018 Jul;33:276-281. doi: 10.1016/j.ebiom.2018.06.017. Epub 2018 Jun 22.


An evidence-based approach to assessing surgical versus clinical diagnosis of symptomatic endometriosis.

Taylor HS, Adamson GD, Diamond MP, Goldstein SR, Horne AW, Missmer SA, Snabes MC, Surrey E, Taylor RN.

Int J Gynaecol Obstet. 2018 Aug;142(2):131-142. doi: 10.1002/ijgo.12521. Epub 2018 May 28. Review.


A pilot randomised double blind controlled trial of the efficacy of purified fatty acids for the treatment of women with endometriosis-associated pain (PurFECT): study protocol.

Abokhrais IM, Saunders PTK, Denison FC, Doust A, Williams L, Horne AW.

Pilot Feasibility Stud. 2018 Apr 25;4:83. doi: 10.1186/s40814-018-0274-8. eCollection 2018.


45% of UK gynaecologists think chronic pelvic pain is managed badly.

Leow HW, Szubert W, Horne AW.

Eur J Obstet Gynecol Reprod Biol. 2018 May;224:200-202. doi: 10.1016/j.ejogrb.2018.03.014. Epub 2018 Mar 10. No abstract available.


Pathophysiology of endometriosis-associated pain: A review of pelvic and central nervous system mechanisms.

Coxon L, Horne AW, Vincent K.

Best Pract Res Clin Obstet Gynaecol. 2018 Aug;51:53-67. doi: 10.1016/j.bpobgyn.2018.01.014. Epub 2018 Feb 15. Review.


Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment.

Ahmad SF, Brown JK, Campbell LL, Koscielniak M, Oliver C, Wheelhouse N, Entrican G, McFee S, Wills GS, McClure MO, Horner PJ, Gaikoumelou S, Lee KF, Critchley HOD, Duncan WC, Horne AW.

EBioMedicine. 2018 Mar;29:159-165. doi: 10.1016/j.ebiom.2018.02.020. Epub 2018 Feb 23.


Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy.

Hastie R, Lim E, Sluka P, Campbell L, Horne AW, Ellett L, Hannan NJ, Brownfoot F, Kaitu'u-Lino TJ, Tong S.

EBioMedicine. 2018 Mar;29:166-176. doi: 10.1016/j.ebiom.2018.01.041. Epub 2018 Feb 2.


GaPP2, a multicentre randomised controlled trial of the efficacy of gabapentin for the management of chronic pelvic pain in women: study protocol.

Vincent K, Baranowski A, Bhattacharya S, Birch J, Cheong Y, Cregg R, Daniels J, Hewitt CA, Macfarlane GJ, Middleton L, Szubert W, Tracey I, Williams ACC, Horne AW.

BMJ Open. 2018 Jan 31;8(1):e014924. doi: 10.1136/bmjopen-2016-014924.


Informing women with endometriosis about ovarian cancer risk.

Kvaskoff M, Horne AW, Missmer SA.

Lancet. 2017 Dec 2;390(10111):2433-2434. doi: 10.1016/S0140-6736(17)33049-0. Epub 2017 Dec 1. No abstract available.


Impact of endometriosis on risk of further gynaecological surgery and cancer: a national cohort study.

Saraswat L, Ayansina D, Cooper KG, Bhattacharya S, Horne AW, Bhattacharya S.

BJOG. 2018 Jan;125(1):64-72. doi: 10.1111/1471-0528.14793. Epub 2017 Sep 27.


Is gabapentin effective for women with unexplained chronic pelvic pain?

Horne AW, Vincent K, Cregg R, Daniels J.

BMJ. 2017 Sep 21;358:j3520. doi: 10.1136/bmj.j3520. No abstract available.


The role of TGF-β in the pathophysiology of peritoneal endometriosis.

Young VJ, Ahmad SF, Duncan WC, Horne AW.

Hum Reprod Update. 2017 Sep 1;23(5):548-559. doi: 10.1093/humupd/dmx016. Review.


Top ten endometriosis research priorities in the UK and Ireland.

Horne AW, Saunders PTK, Abokhrais IM, Hogg L; Endometriosis Priority Setting Partnership Steering Group (appendix).

Lancet. 2017 Jun 3;389(10085):2191-2192. doi: 10.1016/S0140-6736(17)31344-2. Epub 2017 May 18. No abstract available.


Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release.

Giakoumelou S, Wheelhouse N, Brown J, Wade J, Simitsidellis I, Gibson D, Saunders PTK, Horner P, Entrican G, Howie SEM, Horne AW.

Sci Rep. 2017 May 17;7(1):2001. doi: 10.1038/s41598-017-02223-z.


EP2 receptor antagonism reduces peripheral and central hyperalgesia in a preclinical mouse model of endometriosis.

Greaves E, Horne AW, Jerina H, Mikolajczak M, Hilferty L, Mitchell R, Fleetwood-Walker SM, Saunders PT.

Sci Rep. 2017 Mar 10;7:44169. doi: 10.1038/srep44169.


Relevant human tissue resources and laboratory models for use in endometriosis research.

Greaves E, Critchley HOD, Horne AW, Saunders PTK.

Acta Obstet Gynecol Scand. 2017 Jun;96(6):644-658. doi: 10.1111/aogs.13119. Epub 2017 Apr 5. Review.


Cigarette smoking alters sialylation in the Fallopian tube of women, with implications for the pathogenesis of ectopic pregnancy.

Nio-Kobayashi J, Abidin HB, Brown JK, Iwanaga T, Horne AW, Duncan WC.

Mol Reprod Dev. 2016 Dec;83(12):1083-1091. doi: 10.1002/mrd.22747. Epub 2016 Oct 20.


ID2 mediates the transforming growth factor-β1-induced Warburg-like effect seen in the peritoneum of women with endometriosis.

Young VJ, Ahmad SF, Brown JK, Duncan WC, Horne AW.

Mol Hum Reprod. 2016 Sep;22(9):648-54. doi: 10.1093/molehr/gaw045. Epub 2016 Jul 6.


Research Priorities for Endometriosis.

Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice LC, Horne AW, Hull ML, Hummelshoj L, Missmer SA, Montgomery GW, Stratton P, Taylor RN, Rombauts L, Saunders PT, Vincent K, Zondervan KT; WES/WERF Consortium for Research Priorities in Endometriosis.

Reprod Sci. 2017 Feb;24(2):202-226. doi: 10.1177/1933719116654991. Epub 2016 Sep 27.


Pharmaceutical treatments to prevent recurrence of endometriosis following surgery: a model-based economic evaluation.

Sanghera S, Barton P, Bhattacharya S, Horne AW, Roberts TE; PRE-EMPT research group.

BMJ Open. 2016 Apr 15;6(4):e010580. doi: 10.1136/bmjopen-2015-010580.


Gabapentin for the Management of Chronic Pelvic Pain in Women (GaPP1): A Pilot Randomised Controlled Trial.

Lewis SC, Bhattacharya S, Wu O, Vincent K, Jack SA, Critchley HO, Porter MA, Cranley D, Wilson JA, Horne AW.

PLoS One. 2016 Apr 12;11(4):e0153037. doi: 10.1371/journal.pone.0153037. eCollection 2016.


An Exploratory Study into Objective and Reported Characteristics of Neuropathic Pain in Women with Chronic Pelvic Pain.

Whitaker LH, Reid J, Choa A, McFee S, Seretny M, Wilson J, Elton RA, Vincent K, Horne AW.

PLoS One. 2016 Apr 5;11(4):e0151950. doi: 10.1371/journal.pone.0151950. eCollection 2016.


Gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor are expressed at tubal ectopic pregnancy implantation sites.

Peng B, Klausen C, Campbell L, Leung PC, Horne AW, Bedaiwy MA.

Fertil Steril. 2016 Jun;105(6):1620-1627.e3. doi: 10.1016/j.fertnstert.2016.02.003. Epub 2016 Feb 23.


Pregnancy outcomes in women with endometriosis: a national record linkage study.

Saraswat L, Ayansina DT, Cooper KG, Bhattacharya S, Miligkos D, Horne AW, Bhattacharya S.

BJOG. 2017 Feb;124(3):444-452. doi: 10.1111/1471-0528.13920. Epub 2016 Feb 16.


Peritoneal VEGF-A expression is regulated by TGF-β1 through an ID1 pathway in women with endometriosis.

Young VJ, Ahmad SF, Brown JK, Duncan WC, Horne AW.

Sci Rep. 2015 Nov 18;5:16859. doi: 10.1038/srep16859.


The BMEA study: the impact of meridian balanced method electroacupuncture on women with chronic pelvic pain-a three-arm randomised controlled pilot study using a mixed-methods approach.

Chong OT, Critchley HO, Horne AW, Elton R, Haraldsdottir E, Fallon M.

BMJ Open. 2015 Nov 17;5(11):e008621. doi: 10.1136/bmjopen-2015-008621.


Selective modulation of the prostaglandin F2α pathway markedly impacts on endometriosis progression in a xenograft mouse model.

Ahmad SF, Akoum A, Horne AW.

Mol Hum Reprod. 2015 Dec;21(12):905-16. doi: 10.1093/molehr/gav056. Epub 2015 Oct 15.


The role of infection in miscarriage.

Giakoumelou S, Wheelhouse N, Cuschieri K, Entrican G, Howie SE, Horne AW.

Hum Reprod Update. 2016 Jan-Feb;22(1):116-33. doi: 10.1093/humupd/dmv041. Epub 2015 Sep 19. Review.


The Expression and Cellular Localization of Galectin-1 and Galectin-3 in the Fallopian Tube Are Altered in Women with Tubal Ectopic Pregnancy.

Nio-Kobayashi J, Abidin HB, Brown JK, Iwanaga T, Horne AW, Duncan WC.

Cells Tissues Organs. 2015;200(6):424-34. doi: 10.1159/000439166. Epub 2015 Sep 12.


Estradiol is a critical mediator of macrophage-nerve cross talk in peritoneal endometriosis.

Greaves E, Temp J, Esnal-Zufiurre A, Mechsner S, Horne AW, Saunders PT.

Am J Pathol. 2015 Aug;185(8):2286-97. doi: 10.1016/j.ajpath.2015.04.012. Epub 2015 Jun 12.


Molecular diagnostics and therapeutics for ectopic pregnancy.

Tong S, Skubisz MM, Horne AW.

Mol Hum Reprod. 2015 Feb;21(2):126-35. doi: 10.1093/molehr/gau084. Epub 2014 Sep 17.


The peritoneum is both a source and target of TGF-β in women with endometriosis.

Young VJ, Brown JK, Saunders PT, Duncan WC, Horne AW.

PLoS One. 2014 Sep 10;9(9):e106773. doi: 10.1371/journal.pone.0106773. eCollection 2014.


Estrogen receptor (ER) agonists differentially regulate neuroangiogenesis in peritoneal endometriosis via the repellent factor SLIT3.

Greaves E, Collins F, Esnal-Zufiaurre A, Giakoumelou S, Horne AW, Saunders PT.

Endocrinology. 2014 Oct;155(10):4015-26. doi: 10.1210/en.2014-1086. Epub 2014 Jul 22.


Elevated peritoneal expression and estrogen regulation of nociceptive ion channels in endometriosis.

Greaves E, Grieve K, Horne AW, Saunders PT.

J Clin Endocrinol Metab. 2014 Sep;99(9):E1738-43. doi: 10.1210/jc.2014-2282. Epub 2014 Jul 16.


A novel mouse model of endometriosis mimics human phenotype and reveals insights into the inflammatory contribution of shed endometrium.

Greaves E, Cousins FL, Murray A, Esnal-Zufiaurre A, Fassbender A, Horne AW, Saunders PT.

Am J Pathol. 2014 Jul;184(7):1930-9. doi: 10.1016/j.ajpath.2014.03.011. Epub 2014 Jun 5.


Combination gefitinib and methotrexate treatment for non-tubal ectopic pregnancies: a case series.

Horne AW, Skubisz MM, Tong S, Duncan WC, Neil P, Wallace EM, Johns TG.

Hum Reprod. 2014 Jul;29(7):1375-9. Epub 2014 May 7.


Transforming growth factor-β induced Warburg-like metabolic reprogramming may underpin the development of peritoneal endometriosis.

Young VJ, Brown JK, Maybin J, Saunders PT, Duncan WC, Horne AW.

J Clin Endocrinol Metab. 2014 Sep;99(9):3450-9. doi: 10.1210/jc.2014-1026. Epub 2014 May 5.


Quantitative serial MRI of the treated fibroid uterus.

Munro KI, Thrippleton MJ, Williams AR, McKillop G, Walker J, Horne AW, Newby DE, Anderson RA, Semple SI, Marshall I, Lewis SC, Millar RP, Bastin ME, Critchley HO.

PLoS One. 2014 Mar 7;9(3):e89809. doi: 10.1371/journal.pone.0089809. eCollection 2014.


The association between smoking and ectopic pregnancy: why nicotine is BAD for your fallopian tube.

Horne AW, Brown JK, Nio-Kobayashi J, Abidin HB, Adin ZE, Boswell L, Burgess S, Lee KF, Duncan WC.

PLoS One. 2014 Feb 20;9(2):e89400. doi: 10.1371/journal.pone.0089400. eCollection 2014.


Women's satisfaction and symptoms following NovaSure endometrial ablation: a postal questionnaire survey in Lothian, Scotland.

Unger HW, Megaly E, Dick A, Horne AW, Milne S, West C.

J Obstet Gynaecol. 2014 May;34(4):350-1. doi: 10.3109/01443615.2013.876395. Epub 2014 Jan 31.


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