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Gefitinib and Methotrexate to Treat Ectopic Pregnancies with a Pre-Treatment Serum hCG 1000-10,000 IU/L: Phase II Open Label, Single Arm Multi-Centre Trial.

Skubisz MM, Tong S, Doust A, Mollison J, Johns TG, Neil P, Robinson M, Bhattacharya S, Wallace E, Krzys N, Colin Duncan W, Horne AW.

EBioMedicine. 2018 Jun 22. pii: S2352-3964(18)30224-X. doi: 10.1016/j.ebiom.2018.06.017. [Epub ahead of print]


An evidence-based approach to assessing surgical versus clinical diagnosis of symptomatic endometriosis.

Taylor HS, Adamson GD, Diamond MP, Goldstein SR, Horne AW, Missmer SA, Snabes MC, Surrey E, Taylor RN.

Int J Gynaecol Obstet. 2018 Aug;142(2):131-142. doi: 10.1002/ijgo.12521. Epub 2018 May 28. Review.


A pilot randomised double blind controlled trial of the efficacy of purified fatty acids for the treatment of women with endometriosis-associated pain (PurFECT): study protocol.

Abokhrais IM, Saunders PTK, Denison FC, Doust A, Williams L, Horne AW.

Pilot Feasibility Stud. 2018 Apr 25;4:83. doi: 10.1186/s40814-018-0274-8. eCollection 2018.


Caesarean scar pregnancy in the UK: a national cohort study.

Harb HM, Knight M, Bottomley C, Overton C, Tobias A, Gallos ID, Shehmar M, Farquharson R, Horne A, Latthe P, Edi-Osagie E, MacLean M, Marston E, Zamora J, Dawood F, Small R, Ross J, Bourne T, Coomarasamy A, Jurkovic D.

BJOG. 2018 Apr 26. doi: 10.1111/1471-0528.15255. [Epub ahead of print]


Predictors of activity limitation in people with gout: a prospective study.

Stewart S, Rome K, Eason A, House ME, Horne A, Doyle AJ, Knight J, Taylor WJ, Dalbeth N.

Clin Rheumatol. 2018 Aug;37(8):2213-2219. doi: 10.1007/s10067-018-4110-6. Epub 2018 Apr 21.


45% of UK gynaecologists think chronic pelvic pain is managed badly.

Leow HW, Szubert W, Horne AW.

Eur J Obstet Gynecol Reprod Biol. 2018 May;224:200-202. doi: 10.1016/j.ejogrb.2018.03.014. Epub 2018 Mar 10. No abstract available.


Pathophysiology of endometriosis-associated pain: A review of pelvic and central nervous system mechanisms.

Coxon L, Horne AW, Vincent K.

Best Pract Res Clin Obstet Gynaecol. 2018 Feb 15. pii: S1521-6934(18)30032-4. doi: 10.1016/j.bpobgyn.2018.01.014. [Epub ahead of print] Review.


Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment.

Ahmad SF, Brown JK, Campbell LL, Koscielniak M, Oliver C, Wheelhouse N, Entrican G, McFee S, Wills GS, McClure MO, Horner PJ, Gaikoumelou S, Lee KF, Critchley HOD, Duncan WC, Horne AW.

EBioMedicine. 2018 Mar;29:159-165. doi: 10.1016/j.ebiom.2018.02.020. Epub 2018 Feb 23.


Visual Function Metrics in Early and Intermediate Dry Age-related Macular Degeneration for Use as Clinical Trial Endpoints.

Cocce KJ, Stinnett SS, Luhmann UFO, Vajzovic L, Horne A, Schuman SG, Toth CA, Cousins SW, Lad EM.

Am J Ophthalmol. 2018 May;189:127-138. doi: 10.1016/j.ajo.2018.02.012. Epub 2018 Mar 15.


Bone Loss After Romosozumab/Denosumab: Effects of Bisphosphonates.

Horne AM, Mihov B, Reid IR.

Calcif Tissue Int. 2018 Jul;103(1):55-61. doi: 10.1007/s00223-018-0404-6. Epub 2018 Feb 14.


Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy.

Hastie R, Lim E, Sluka P, Campbell L, Horne AW, Ellett L, Hannan NJ, Brownfoot F, Kaitu'u-Lino TJ, Tong S.

EBioMedicine. 2018 Mar;29:166-176. doi: 10.1016/j.ebiom.2018.01.041. Epub 2018 Feb 2.


Longitudinal Examination of Aggression and Study Skills From Middle to High School: Implications for Dropout Prevention.

Orpinas P, Raczynski K, Hsieh HL, Nahapetyan L, Horne AM.

J Sch Health. 2018 Mar;88(3):246-252. doi: 10.1111/josh.12602.


GaPP2, a multicentre randomised controlled trial of the efficacy of gabapentin for the management of chronic pelvic pain in women: study protocol.

Vincent K, Baranowski A, Bhattacharya S, Birch J, Cheong Y, Cregg R, Daniels J, Hewitt CA, Macfarlane GJ, Middleton L, Szubert W, Tracey I, Williams ACC, Horne AW.

BMJ Open. 2018 Jan 31;8(1):e014924. doi: 10.1136/bmjopen-2016-014924.


The impact of diuretic use and ABCG2 genotype on the predictive performance of a published allopurinol dosing tool.

Wright DFB, Dalbeth N, Phipps-Green AJ, Merriman TR, Barclay ML, Drake J, Tan P, Horne A, Stamp LK.

Br J Clin Pharmacol. 2018 May;84(5):937-943. doi: 10.1111/bcp.13516. Epub 2018 Feb 20.


Association of Low Luminance Questionnaire With Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration.

Thompson AC, Luhmann UFO, Stinnett SS, Vajzovic L, Horne A, Toth CA, Cousins SW, Lad EM.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):289-297. doi: 10.1167/iovs.17-22528.


The effect of kidney function on the urate lowering effect and safety of increasing allopurinol above doses based on creatinine clearance: a post hoc analysis of a randomized controlled trial.

Stamp LK, Chapman PT, Barclay M, Horne A, Frampton C, Tan P, Drake J, Dalbeth N.

Arthritis Res Ther. 2017 Dec 21;19(1):283. doi: 10.1186/s13075-017-1491-x.


Informing women with endometriosis about ovarian cancer risk.

Kvaskoff M, Horne AW, Missmer SA.

Lancet. 2017 Dec 2;390(10111):2433-2434. doi: 10.1016/S0140-6736(17)33049-0. Epub 2017 Dec 1. No abstract available.


Parenting a Child with Juvenile Idiopathic Arthritis, Orofacial Pain, and Dysfunction: A Qualitative Study.

Leksell E, Hallberg U, Horne A, Ernberg M, Hedenberg-Magnusson B.

J Oral Facial Pain Headache. 2017 Fall;31(4):353–361. doi: 10.11607/ofph.1689. Epub 2017 Oct 10.


Lack of Evidence that Soluble Urate Directly Influences Bone Remodelling: A Laboratory and Clinical Study.

Dalbeth N, Pool B, Chhana A, Lin JM, Tay ML, Tan P, Callon KE, Naot D, Horne A, Drake J, Gamble GD, Reid IR, Grey A, Stamp LK, Cornish J.

Calcif Tissue Int. 2018 Jan;102(1):73-84. doi: 10.1007/s00223-017-0328-6. Epub 2017 Oct 10.


Impact of endometriosis on risk of further gynaecological surgery and cancer: a national cohort study.

Saraswat L, Ayansina D, Cooper KG, Bhattacharya S, Horne AW, Bhattacharya S.

BJOG. 2018 Jan;125(1):64-72. doi: 10.1111/1471-0528.14793. Epub 2017 Sep 27.


Influence of genetic variants on renal uric acid handling in response to frusemide: an acute intervention study.

Dalbeth N, Allan J, Gamble GD, Phipps-Green A, Flynn TJ, Mihov B, Horne A, Doughty R, Stamp LK, Merriman TR.

RMD Open. 2017 Apr 11;3(1):e000424. doi: 10.1136/rmdopen-2016-000424. eCollection 2017.


Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study.

Bergsten E, Horne A, Aricó M, Astigarraga I, Egeler RM, Filipovich AH, Ishii E, Janka G, Ladisch S, Lehmberg K, McClain KL, Minkov M, Montgomery S, Nanduri V, Rosso D, Henter JI.

Blood. 2017 Dec 21;130(25):2728-2738. doi: 10.1182/blood-2017-06-788349. Epub 2017 Sep 21.


Is gabapentin effective for women with unexplained chronic pelvic pain?

Horne AW, Vincent K, Cregg R, Daniels J.

BMJ. 2017 Sep 21;358:j3520. doi: 10.1136/bmj.j3520. No abstract available.


The role of TGF-β in the pathophysiology of peritoneal endometriosis.

Young VJ, Ahmad SF, Duncan WC, Horne AW.

Hum Reprod Update. 2017 Sep 1;23(5):548-559. doi: 10.1093/humupd/dmx016. Review.


Duration of antiresorptive activity of zoledronate in postmenopausal women with osteopenia: a randomized, controlled multidose trial.

Grey A, Bolland MJ, Horne A, Mihov B, Gamble G, Reid IR.

CMAJ. 2017 Sep 11;189(36):E1130-E1136. doi: 10.1503/cmaj.161207.


Comparison of Orthodontic Medicaid Funding in the United States 2006 to 2015.

Minick G, Tilliss T, Shellhart WC, Newman SM, Carey CM, Horne A, Whitt S, Oesterle LJ.

Front Public Health. 2017 Aug 22;5:221. doi: 10.3389/fpubh.2017.00221. eCollection 2017.


Allopurinol dose escalation to achieve serum urate below 6 mg/dL: an open-label extension study.

Stamp LK, Chapman PT, Barclay M, Horne A, Frampton C, Tan P, Drake J, Dalbeth N.

Ann Rheum Dis. 2017 Dec;76(12):2065-2070. doi: 10.1136/annrheumdis-2017-211873. Epub 2017 Aug 22.


Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome.

Minoia F, Bovis F, Davì S, Insalaco A, Lehmberg K, Shenoi S, Weitzman S, Espada G, Gao YJ, Anton J, Kitoh T, Kasapcopur O, Sanner H, Merino R, Astigarraga I, Alessio M, Jeng M, Chasnyk V, Nichols KE, Huasong Z, Li C, Micalizzi C, Ruperto N, Martini A, Cron RQ, Ravelli A, Horne A; Pediatric Rheumatology International Trials Organization, the Childhood Arthritis and Rheumatology Research Alliance, the Pediatric Rheumatology Collaborative Study Group, and the Histiocyte Society.

J Pediatr. 2017 Oct;189:72-78.e3. doi: 10.1016/j.jpeds.2017.06.005. Epub 2017 Aug 12.


Do the Hard Things First: A Randomized Controlled Trial Testing the Effects of Exemplar Selection on Generalization Following Therapy for Grammatical Morphology.

Van Horne AJO, Fey M, Curran M.

J Speech Lang Hear Res. 2017 Sep 18;60(9):2569-2588. doi: 10.1044/2017_JSLHR-L-17-0001.


Effect of monthly high-dose vitamin D on bone density in community-dwelling older adults substudy of a randomized controlled trial.

Reid IR, Horne AM, Mihov B, Gamble GD, Al-Abuwsi F, Singh M, Taylor L, Fenwick S, Camargo CA, Stewart AW, Scragg R.

J Intern Med. 2017 Nov;282(5):452-460. doi: 10.1111/joim.12651. Epub 2017 Jul 26.


Dietary calcium intake and rate of bone loss in men.

Bristow SM, Gamble GD, Horne AM, Reid IR.

Br J Nutr. 2017 May;117(10):1432-1438. doi: 10.1017/S0007114517001301. Epub 2017 Jun 13.


Informing Environmental Water Management Decisions: Using Conditional Probability Networks to Address the Information Needs of Planning and Implementation Cycles.

Horne AC, Szemis JM, Webb JA, Kaur S, Stewardson MJ, Bond N, Nathan R.

Environ Manage. 2018 Mar;61(3):347-357. doi: 10.1007/s00267-017-0874-8. Epub 2017 Jun 5.


Comparison of Frequency of Referral to Cardiothoracic Surgery for Aortic Valve Disease in Blacks, Hispanics, and Whites.

Cruz Rodriguez B, Acharya P, Salazar-Fields C, Horne A Jr.

Am J Cardiol. 2017 Aug 1;120(3):450-455. doi: 10.1016/j.amjcard.2017.04.048. Epub 2017 May 11.


Top ten endometriosis research priorities in the UK and Ireland.

Horne AW, Saunders PTK, Abokhrais IM, Hogg L; Endometriosis Priority Setting Partnership Steering Group (appendix).

Lancet. 2017 Jun 3;389(10085):2191-2192. doi: 10.1016/S0140-6736(17)31344-2. Epub 2017 May 18. No abstract available.


Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release.

Giakoumelou S, Wheelhouse N, Brown J, Wade J, Simitsidellis I, Gibson D, Saunders PTK, Horner P, Entrican G, Howie SEM, Horne AW.

Sci Rep. 2017 May 17;7(1):2001. doi: 10.1038/s41598-017-02223-z.


Bone Loss After Denosumab: Only Partial Protection with Zoledronate.

Reid IR, Horne AM, Mihov B, Gamble GD.

Calcif Tissue Int. 2017 Oct;101(4):371-374. doi: 10.1007/s00223-017-0288-x. Epub 2017 May 13.


A randomised controlled trial of the efficacy and safety of allopurinol dose escalation to achieve target serum urate in people with gout.

Stamp LK, Chapman PT, Barclay ML, Horne A, Frampton C, Tan P, Drake J, Dalbeth N.

Ann Rheum Dis. 2017 Sep;76(9):1522-1528. doi: 10.1136/annrheumdis-2016-210872. Epub 2017 Mar 17.


EP2 receptor antagonism reduces peripheral and central hyperalgesia in a preclinical mouse model of endometriosis.

Greaves E, Horne AW, Jerina H, Mikolajczak M, Hilferty L, Mitchell R, Fleetwood-Walker SM, Saunders PT.

Sci Rep. 2017 Mar 10;7:44169. doi: 10.1038/srep44169.


Relevant human tissue resources and laboratory models for use in endometriosis research.

Greaves E, Critchley HOD, Horne AW, Saunders PTK.

Acta Obstet Gynecol Scand. 2017 Jun;96(6):644-658. doi: 10.1111/aogs.13119. Epub 2017 Apr 5. Review.


Effect of single-dose dexamethasone on acute phase response following zoledronic acid: a randomized controlled trial.

Billington EO, Horne A, Gamble GD, Maslowski K, House M, Reid IR.

Osteoporos Int. 2017 Jun;28(6):1867-1874. doi: 10.1007/s00198-017-3960-0. Epub 2017 Feb 23.


Randomised trial assessing the impact of framing of fracture risk and osteoporosis treatment benefits in patients undergoing bone densitometry.

Kalluru R, Petrie KJ, Grey A, Nisa Z, Horne AM, Gamble GD, Bolland MJ.

BMJ Open. 2017 Feb 10;7(2):e013703. doi: 10.1136/bmjopen-2016-013703.


Reducing Antibiotic Exposure in Suspected Neonatal Sepsis.

Grant CH, Arnott A, Brook T, Horne A, Hurst W, Kelly S, Lang C, Payne M, Pert H, Sparrow S, Dokubo PA, Bee N, Gibbs R, Becher JC.

Clin Pediatr (Phila). 2018 Jan;57(1):76-81. doi: 10.1177/0009922816689673. Epub 2017 Feb 3.


How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?

Horne A, Wickström R, Jordan MB, Yeh EA, Naqvi A, Henter JI, Janka G.

Curr Treat Options Neurol. 2017 Jan;19(1):3. doi: 10.1007/s11940-017-0439-4. Review.


Predictors of Mortality in People with Recent-onset Gout: A Prospective Observational Study.

Vincent ZL, Gamble G, House M, Knight J, Horne A, Taylor WJ, Dalbeth N.

J Rheumatol. 2017 Mar;44(3):368-373. doi: 10.3899/jrheum.160596. Epub 2016 Dec 15.


The Relationship Between Grammatical Development and Disfluencies in Preschool Children Who Stutter and Those Who Recover.

Hollister J, Van Horne AO, Zebrowski P.

Am J Speech Lang Pathol. 2017 Feb 1;26(1):44-56. doi: 10.1044/2016_AJSLP-15-0022.


Illness Perceptions and Mortality in Patients With Gout: A Prospective Observational Study.

Serlachius A, Gamble G, House M, Vincent ZL, Knight J, Horne A, Taylor WJ, Petrie KJ, Dalbeth N.

Arthritis Care Res (Hoboken). 2017 Sep;69(9):1444-1448. doi: 10.1002/acr.23147. Epub 2017 Aug 13.


Relationship of bone erosion with the urate and soft tissue components of the tophus in gout: a dual energy computed tomography study.

Sapsford M, Gamble GD, Aati O, Knight J, Horne A, Doyle AJ, Dalbeth N.

Rheumatology (Oxford). 2017 Jan;56(1):129-133. doi: 10.1093/rheumatology/kew383. Epub 2016 Nov 1.


Cigarette smoking alters sialylation in the Fallopian tube of women, with implications for the pathogenesis of ectopic pregnancy.

Nio-Kobayashi J, Abidin HB, Brown JK, Iwanaga T, Horne AW, Duncan WC.

Mol Reprod Dev. 2016 Dec;83(12):1083-1091. doi: 10.1002/mrd.22747. Epub 2016 Oct 20.


Teaching Clinical Ophthalmology: Medical Student Feedback on Team Case-Based Versus Lecture Format.

Horne A, Rosdahl J.

J Surg Educ. 2017 Mar - Apr;74(2):329-332. doi: 10.1016/j.jsurg.2016.08.009. Epub 2016 Sep 16.


Urate crystal deposition and bone erosion in gout: 'inside-out' or 'outside-in'? A dual-energy computed tomography study.

Towiwat P, Doyle AJ, Gamble GD, Tan P, Aati O, Horne A, Stamp LK, Dalbeth N.

Arthritis Res Ther. 2016 Sep 15;18(1):208. doi: 10.1186/s13075-016-1105-z.

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