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Items: 1 to 50 of 78

1.

Platelet Acetyl-CoA Carboxylase Phosphorylation: A Risk Stratification Marker That Reveals Platelet-Lipid Interplay in Coronary Artery Disease Patients.

Kautbally S, Lepropre S, Onselaer MB, Le Rigoleur A, Ginion A, De Meester de Ravenstein C, Ambroise J, Boudjeltia KZ, Octave M, Wéra O, Hego A, Pincemail J, Cheramy-Bien JP, Huby T, Giera M, Gerber B, Pouleur AC, Guigas B, Vanoverschelde JL, Kefer J, Bertrand L, Oury C, Horman S, Beauloye C.

JACC Basic Transl Sci. 2019 Sep 11;4(5):596-610. doi: 10.1016/j.jacbts.2019.04.005. eCollection 2019 Sep.

2.

Clinical Protocol to Prevent Thrombogenic Effect of Liver-Derived Mesenchymal Cells for Cell-Based Therapies.

Coppin L, Najimi M, Bodart J, Rouchon MS, van der Smissen P, Eeckhoudt S, Dahlqvist G, Castanares-Zapatero D, Komuta M, Brouns SL, Baaten CC, Heemskerk JWM, Horman S, Belmonte N, Sokal E, Stéphenne X.

Cells. 2019 Aug 7;8(8). pii: E846. doi: 10.3390/cells8080846.

3.

GABABR-Mediated Paraneoplastic Limbic Encephalitis Due To Thymic Small Cell Carcinoma.

Bordin-Wosk T, Patel SP, Horman SF.

J Gen Intern Med. 2019 Aug;34(8):1658-1661. doi: 10.1007/s11606-019-05040-4. Epub 2019 May 6.

PMID:
31062226
4.

Role of AMP-activated protein kinase in sepsis-induced cardiovascular dysfunction.

Angé M, Castanares-Zapatero D, Bertrand L, Horman S, Beauloye C.

Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H934-H935. doi: 10.1152/ajpheart.00015.2019. No abstract available.

PMID:
30946604
5.

AMP-Activated Protein Kinase and O-GlcNAcylation, Two Partners Tightly Connected to Regulate Key Cellular Processes.

Gélinas R, Dontaine J, Horman S, Beauloye C, Bultot L, Bertrand L.

Front Endocrinol (Lausanne). 2018 Sep 13;9:519. doi: 10.3389/fendo.2018.00519. eCollection 2018. Review.

6.

Co-regulatory networks of human serum proteins link genetics to disease.

Emilsson V, Ilkov M, Lamb JR, Finkel N, Gudmundsson EF, Pitts R, Hoover H, Gudmundsdottir V, Horman SR, Aspelund T, Shu L, Trifonov V, Sigurdsson S, Manolescu A, Zhu J, Olafsson Ö, Jakobsdottir J, Lesley SA, To J, Zhang J, Harris TB, Launer LJ, Zhang B, Eiriksdottir G, Yang X, Orth AP, Jennings LL, Gudnason V.

Science. 2018 Aug 24;361(6404):769-773. doi: 10.1126/science.aaq1327. Epub 2018 Aug 2.

7.

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.

Lepropre S, Kautbally S, Octave M, Ginion A, Onselaer MB, Steinberg GR, Kemp BE, Hego A, Wéra O, Brouns S, Swieringa F, Giera M, Darley-Usmar VM, Ambroise J, Guigas B, Heemskerk J, Bertrand L, Oury C, Beauloye C, Horman S.

Blood. 2018 Sep 13;132(11):1180-1192. doi: 10.1182/blood-2018-02-831503. Epub 2018 Jul 17.

8.

The Regulation of Insulin-Stimulated Cardiac Glucose Transport via Protein Acetylation.

Renguet E, Bultot L, Beauloye C, Horman S, Bertrand L.

Front Cardiovasc Med. 2018 Jun 12;5:70. doi: 10.3389/fcvm.2018.00070. eCollection 2018. Review. Erratum in: Front Cardiovasc Med. 2018 Jul 12;5:103.

9.

Studying the Role of AMPK in Cardiac Hypertrophy and Protein Synthesis.

Mailleux F, Beauloye C, Balligand JL, Horman S, Bertrand L.

Methods Mol Biol. 2018;1732:321-342. doi: 10.1007/978-1-4939-7598-3_21.

PMID:
29480485
10.

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation.

Gélinas R, Mailleux F, Dontaine J, Bultot L, Demeulder B, Ginion A, Daskalopoulos EP, Esfahani H, Dubois-Deruy E, Lauzier B, Gauthier C, Olson AK, Bouchard B, Des Rosiers C, Viollet B, Sakamoto K, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S, Bertrand L.

Nat Commun. 2018 Jan 25;9(1):374. doi: 10.1038/s41467-017-02795-4.

11.

Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets.

Horman SR, To J, Lamb J, Zoll JH, Leonetti N, Tu B, Moran R, Newlin R, Walker JR, Orth AP.

Oncotarget. 2017 Oct 20;8(59):99913-99930. doi: 10.18632/oncotarget.21915. eCollection 2017 Nov 21.

12.

Cardiac myocyte β3-adrenergic receptors prevent myocardial fibrosis by modulating oxidant stress-dependent paracrine signaling.

Hermida N, Michel L, Esfahani H, Dubois-Deruy E, Hammond J, Bouzin C, Markl A, Colin H, Steenbergen AV, De Meester C, Beauloye C, Horman S, Yin X, Mayr M, Balligand JL.

Eur Heart J. 2018 Mar 7;39(10):888-898. doi: 10.1093/eurheartj/ehx366.

PMID:
29106524
13.

Chronic Intermittent Hypoxia Impairs Insulin Sensitivity but Improves Whole-Body Glucose Tolerance by Activating Skeletal Muscle AMPK.

Thomas A, Belaidi E, Moulin S, Horman S, van der Zon GC, Viollet B, Levy P, Bertrand L, Pepin JL, Godin-Ribuot D, Guigas B.

Diabetes. 2017 Dec;66(12):2942-2951. doi: 10.2337/db17-0186. Epub 2017 Sep 7.

14.

Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake.

Renguet E, Ginion A, Gélinas R, Bultot L, Auquier J, Robillard Frayne I, Daneault C, Vanoverschelde JL, Des Rosiers C, Hue L, Horman S, Beauloye C, Bertrand L.

Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H432-H445. doi: 10.1152/ajpheart.00738.2016. Epub 2017 Jun 23.

15.

Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart.

Van Steenbergen A, Balteau M, Ginion A, Ferté L, Battault S, Ravenstein CM, Balligand JL, Daskalopoulos EP, Gilon P, Despa F, Despa S, Vanoverschelde JL, Horman S, Koepsell H, Berry G, Hue L, Bertrand L, Beauloye C.

Sci Rep. 2017 Jan 27;7:41166. doi: 10.1038/srep41166.

16.

Impact of Hyperglycemia and Low Oxygen Tension on Adipose-Derived Stem Cells Compared with Dermal Fibroblasts and Keratinocytes: Importance for Wound Healing in Type 2 Diabetes.

Lafosse A, Dufeys C, Beauloye C, Horman S, Dufrane D.

PLoS One. 2016 Dec 19;11(12):e0168058. doi: 10.1371/journal.pone.0168058. eCollection 2016.

17.

AMPK in Cardiovascular Diseases.

Daskalopoulos EP, Dufeys C, Beauloye C, Bertrand L, Horman S.

Exp Suppl. 2016;107:179-201. Review.

PMID:
27812981
18.

Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK.

Angin Y, Beauloye C, Horman S, Bertrand L.

Exp Suppl. 2016;107:23-43. Review.

PMID:
27812975
19.

Fifteen days of 3,200 m simulated hypoxia marginally regulates markers for protein synthesis and degradation in human skeletal muscle.

D'Hulst G, Ferri A, Naslain D, Bertrand L, Horman S, Francaux M, Bishop DJ, Deldicque L.

Hypoxia (Auckl). 2016 Mar 3;4:1-14. eCollection 2016.

20.

O-GlcNAcylation, enemy or ally during cardiac hypertrophy development?

Mailleux F, Gélinas R, Beauloye C, Horman S, Bertrand L.

Biochim Biophys Acta. 2016 Dec;1862(12):2232-2243. doi: 10.1016/j.bbadis.2016.08.012. Epub 2016 Aug 17. Review.

21.

STK39 and WNK1 Are Potential Hypertension Susceptibility Genes in the BELHYPGEN Cohort.

Persu A, Evenepoel L, Jin Y, Mendola A, Ngueta G, Yang WY, Gruson D, Horman S, Staessen JA, Vikkula M; BELHYPGEN Consortium.

Medicine (Baltimore). 2016 Apr;95(15):e2968. doi: 10.1097/MD.0000000000002968.

22.

Involvement of mTOR and Regulation by AMPK in Early Iodine Deficiency-Induced Thyroid Microvascular Activation.

Craps J, Joris V, De Jongh B, Sonveaux P, Horman S, Lengelé B, Bertrand L, Many MC, Colin IM, Gérard AC.

Endocrinology. 2016 Jun;157(6):2545-59. doi: 10.1210/en.2015-1911. Epub 2016 Apr 1.

PMID:
27035650
23.

AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.

Daskalopoulos EP, Dufeys C, Bertrand L, Beauloye C, Horman S.

J Mol Cell Cardiol. 2016 Feb;91:188-200. doi: 10.1016/j.yjmcc.2016.01.001. Epub 2016 Jan 7. Review.

PMID:
26772531
24.

Hypothermic continuous machine perfusion enables preservation of energy charge and functional recovery of heart grafts in an ex vivo model of donation following circulatory death.

Van Caenegem O, Beauloye C, Bertrand L, Horman S, Lepropre S, Sparavier G, Vercruysse J, Bethuyne N, Poncelet AJ, Gianello P, Demuylder P, Legrand E, Beaurin G, Bontemps F, Jacquet LM, Vanoverschelde JL.

Eur J Cardiothorac Surg. 2016 May;49(5):1348-53. doi: 10.1093/ejcts/ezv409. Epub 2015 Nov 24.

PMID:
26604296
25.

Even is better than odd: one fat may conceal another.

Beauloye C, Horman S, Bertrand L.

Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1112-4. doi: 10.1152/ajpheart.00620.2015. Epub 2015 Aug 21. No abstract available.

26.

AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.

Sung MM, Zordoky BN, Bujak AL, Lally JS, Fung D, Young ME, Horman S, Miller EJ, Light PE, Kemp BE, Steinberg GR, Dyck JR.

Cardiovasc Res. 2015 Jul 15;107(2):235-45. doi: 10.1093/cvr/cvv166. Epub 2015 May 28.

27.

Challenges and opportunities toward enabling phenotypic screening of complex and 3D cell models.

Horman SR, Hogan C, Delos Reyes K, Lo F, Antczak C.

Future Med Chem. 2015;7(4):513-25. doi: 10.4155/fmc.14.163. Review.

PMID:
25875876
28.

Hypothermic continuous machine perfusion improves metabolic preservation and functional recovery in heart grafts.

Van Caenegem O, Beauloye C, Vercruysse J, Horman S, Bertrand L, Bethuyne N, Poncelet AJ, Gianello P, Demuylder P, Legrand E, Beaurin G, Bontemps F, Jacquet LM, Vanoverschelde JL.

Transpl Int. 2015 Feb;28(2):224-31. doi: 10.1111/tri.12468. Epub 2014 Oct 24.

29.

AMPK activation by glucagon-like peptide-1 prevents NADPH oxidase activation induced by hyperglycemia in adult cardiomyocytes.

Balteau M, Van Steenbergen A, Timmermans AD, Dessy C, Behets-Wydemans G, Tajeddine N, Castanares-Zapatero D, Gilon P, Vanoverschelde JL, Horman S, Hue L, Bertrand L, Beauloye C.

Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1120-33. doi: 10.1152/ajpheart.00210.2014. Epub 2014 Aug 15.

30.

Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1.

Noppe G, Dufeys C, Buchlin P, Marquet N, Castanares-Zapatero D, Balteau M, Hermida N, Bouzin C, Esfahani H, Viollet B, Bertrand L, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S.

J Mol Cell Cardiol. 2014 Sep;74:32-43. doi: 10.1016/j.yjmcc.2014.04.018. Epub 2014 May 5.

PMID:
24805196
31.

A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake.

Timmermans AD, Balteau M, Gélinas R, Renguet E, Ginion A, de Meester C, Sakamoto K, Balligand JL, Bontemps F, Vanoverschelde JL, Horman S, Beauloye C, Bertrand L.

Am J Physiol Heart Circ Physiol. 2014 Jun 15;306(12):H1619-30. doi: 10.1152/ajpheart.00965.2013. Epub 2014 Apr 18.

32.

The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets.

Onselaer MB, Oury C, Hunter RW, Eeckhoudt S, Barile N, Lecut C, Morel N, Viollet B, Jacquet LM, Bertrand L, Sakamoto K, Vanoverschelde JL, Beauloye C, Horman S.

J Thromb Haemost. 2014 Jun;12(6):973-86. doi: 10.1111/jth.12568.

33.

Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.

Velu CS, Chaubey A, Phelan JD, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcucci G, Bhat B, Gebelein B, Grimes HL.

J Clin Invest. 2014 Jan;124(1):222-36. doi: 10.1172/JCI66005. Epub 2013 Dec 16.

34.

Redundant control of migration and adhesion by ERM proteins in vascular smooth muscle cells.

Baeyens N, Latrache I, Yerna X, Noppe G, Horman S, Morel N.

Biochem Biophys Res Commun. 2013 Nov 22;441(3):579-85. doi: 10.1016/j.bbrc.2013.10.118. Epub 2013 Oct 30.

PMID:
24184478
35.

Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.

de Meester C, Timmermans AD, Balteau M, Ginion A, Roelants V, Noppe G, Porporato PE, Sonveaux P, Viollet B, Sakamoto K, Feron O, Horman S, Vanoverschelde JL, Beauloye C, Bertrand L.

Cardiovasc Res. 2014 Jan 1;101(1):20-9. doi: 10.1093/cvr/cvt227. Epub 2013 Oct 8.

PMID:
24104879
36.

Connection between cardiac vascular permeability, myocardial edema, and inflammation during sepsis: role of the α1AMP-activated protein kinase isoform.

Castanares-Zapatero D, Bouleti C, Sommereyns C, Gerber B, Lecut C, Mathivet T, Horckmans M, Communi D, Foretz M, Vanoverschelde JL, Germain S, Bertrand L, Laterre PF, Oury C, Viollet B, Horman S, Beauloye C.

Crit Care Med. 2013 Dec;41(12):e411-22. doi: 10.1097/CCM.0b013e31829866dc.

PMID:
23963133
37.

An HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics.

Horman SR, To J, Orth AP.

J Biomol Screen. 2013 Dec;18(10):1298-308. doi: 10.1177/1087057113499405. Epub 2013 Aug 5.

PMID:
23918920
38.

Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets.

Horman SR, Janas MM, Litterst C, Wang B, MacRae IJ, Sever MJ, Morrissey DV, Graves P, Luo B, Umesalma S, Qi HH, Miraglia LJ, Novina CD, Orth AP.

Mol Cell. 2013 May 9;50(3):356-67. doi: 10.1016/j.molcel.2013.03.015. Epub 2013 Apr 18.

39.

HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome.

Hermida N, Markl A, Hamelet J, Van Assche T, Vanderper A, Herijgers P, van Bilsen M, Hilfiker-Kleiner D, Noppe G, Beauloye C, Horman S, Balligand JL.

Cardiovasc Res. 2013 Jul 1;99(1):44-54. doi: 10.1093/cvr/cvt070. Epub 2013 Mar 29.

PMID:
23542580
40.

Differential regulation of eEF2 and p70S6K by AMPKalpha2 in heart.

Demeulder B, Zarrinpashneh E, Ginion A, Viollet B, Hue L, Rider MH, Vanoverschelde JL, Beauloye C, Horman S, Bertrand L.

Biochim Biophys Acta. 2013 Jun;1832(6):780-90. doi: 10.1016/j.bbadis.2013.02.015. Epub 2013 Mar 4.

41.

Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.

Khandanpour C, Phelan JD, Vassen L, Schütte J, Chen R, Horman SR, Gaudreau MC, Krongold J, Zhu J, Paul WE, Dührsen U, Göttgens B, Grimes HL, Möröy T.

Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011.

42.

AMP-activated protein kinase in the control of cardiac metabolism and remodeling.

Horman S, Beauloye C, Vanoverschelde JL, Bertrand L.

Curr Heart Fail Rep. 2012 Sep;9(3):164-73. doi: 10.1007/s11897-012-0102-z. Review.

PMID:
22767403
43.

NADPH oxidase activation by hyperglycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1.

Balteau M, Tajeddine N, de Meester C, Ginion A, Des Rosiers C, Brady NR, Sommereyns C, Horman S, Vanoverschelde JL, Gailly P, Hue L, Bertrand L, Beauloye C.

Cardiovasc Res. 2011 Nov 1;92(2):237-46. doi: 10.1093/cvr/cvr230. Epub 2011 Aug 22.

PMID:
21859816
44.

Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.

Ginion A, Auquier J, Benton CR, Mouton C, Vanoverschelde JL, Hue L, Horman S, Beauloye C, Bertrand L.

Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H469-77. doi: 10.1152/ajpheart.00986.2010. Epub 2011 May 20.

45.

AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure.

Beauloye C, Bertrand L, Horman S, Hue L.

Cardiovasc Res. 2011 May 1;90(2):224-33. doi: 10.1093/cvr/cvr034. Epub 2011 Feb 1. Review.

PMID:
21285292
46.

Identification and functional implication of a Rho kinase-dependent moesin-EBP50 interaction in noradrenaline-stimulated artery.

Baeyens N, Horman S, Vertommen D, Rider M, Morel N.

Am J Physiol Cell Physiol. 2010 Dec;299(6):C1530-40. doi: 10.1152/ajpcell.00175.2010. Epub 2010 Oct 6.

47.

AMPK inhibition in health and disease.

Viollet B, Horman S, Leclerc J, Lantier L, Foretz M, Billaud M, Giri S, Andreelli F.

Crit Rev Biochem Mol Biol. 2010 Aug;45(4):276-95. doi: 10.3109/10409238.2010.488215. Review.

48.

AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells.

Miranda L, Carpentier S, Platek A, Hussain N, Gueuning MA, Vertommen D, Ozkan Y, Sid B, Hue L, Courtoy PJ, Rider MH, Horman S.

Biochem Biophys Res Commun. 2010 Jun 4;396(3):656-61. doi: 10.1016/j.bbrc.2010.04.151. Epub 2010 May 8.

PMID:
20438708
49.

Gfi1 integrates progenitor versus granulocytic transcriptional programming.

Horman SR, Velu CS, Chaubey A, Bourdeau T, Zhu J, Paul WE, Gebelein B, Grimes HL.

Blood. 2009 May 28;113(22):5466-75. doi: 10.1182/blood-2008-09-179747. Epub 2009 Apr 3.

50.

AMPK: Lessons from transgenic and knockout animals.

Viollet B, Athea Y, Mounier R, Guigas B, Zarrinpashneh E, Horman S, Lantier L, Hebrard S, Devin-Leclerc J, Beauloye C, Foretz M, Andreelli F, Ventura-Clapier R, Bertrand L.

Front Biosci (Landmark Ed). 2009 Jan 1;14:19-44. Review.

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