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Influence of Age on Cardiorespiratory Kinetics During Sinusoidal Walking in Humans.

Ebine N, Ahad-Abdulkarim-D A, Miyake Y, Hojo T, Abe D, Horiuchi M, Fukuoka Y.

Front Physiol. 2018 Aug 24;9:1191. doi: 10.3389/fphys.2018.01191. eCollection 2018.


Impact of Resistance Exercise under Hypoxia on Postexercise Hemodynamics in Healthy Young Males.

Horiuchi M, Ni-I-Nou A, Miyazaki M, Ando D, Koyama K.

Int J Hypertens. 2018 Jul 26;2018:1456972. doi: 10.1155/2018/1456972. eCollection 2018.


The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1.

Horiuchi M, Kuga T, Saito Y, Nagano M, Adachi J, Tomonaga T, Yamaguchi N, Nakayama Y.

J Biol Chem. 2018 Oct 5;293(40):15524-15537. doi: 10.1074/jbc.RA118.002784. Epub 2018 Aug 22.


Retrograde Transport by Clathrin-Coated Vesicles is Involved in Intracellular Transport of PrPSc in Persistently Prion-Infected Cells.

Yamasaki T, Suzuki A, Hasebe R, Horiuchi M.

Sci Rep. 2018 Aug 16;8(1):12241. doi: 10.1038/s41598-018-30775-1.


Impact of Wearing Graduated Compression Stockings on Psychological and Physiological Responses during Prolonged Sitting.

Horiuchi M, Takiguchi C, Kirihara Y, Horiuchi Y.

Int J Environ Res Public Health. 2018 Aug 10;15(8). pii: E1710. doi: 10.3390/ijerph15081710.


Attenuation of stroke damage by angiotensin II type 2 receptor stimulation via peroxisome proliferator-activated receptor-gamma activation.

Shan BS, Mogi M, Iwanami J, Bai HY, Kan-No H, Higaki A, Min LJ, Horiuchi M.

Hypertens Res. 2018 Oct;41(10):839-848. doi: 10.1038/s41440-018-0082-9. Epub 2018 Aug 8.


Deletion of interferon-regulatory factor-1 results in cognitive impairment.

Mogi M, Iwanami J, Wang XL, Tsukuda K, Kan-No H, Bai HY, Shan BS, Higaki A, Min LJ, Horiuchi M.

Hypertens Res. 2018 Oct;41(10):809-816. doi: 10.1038/s41440-018-0080-y. Epub 2018 Aug 6.


Search of Neuroprotective Polyphenols Using the "Overlay" Isolation Method.

Sakagami H, Shi H, Bandow K, Tomomura M, Tomomura A, Horiuchi M, Fujisawa T, Oizumi T.

Molecules. 2018 Jul 24;23(8). pii: E1840. doi: 10.3390/molecules23081840.


Validation of previous prognostic models for thrombosis and exploration of modified models in patients with essential thrombocythemia.

Hashimoto Y, Nakamae H, Tanaka T, Omura H, Horiuchi M, Yoshimura T, Takakuwa T, Mugitani A, Hirose A, Nakamae M, Koh H, Hino M.

Eur J Haematol. 2018 Oct;101(4):508-513. doi: 10.1111/ejh.13136. Epub 2018 Aug 31.


Impact of ambient temperature on energy cost and economical speed during level walking in healthy young males.

Horiuchi M, Handa Y, Fukuoka Y.

Biol Open. 2018 Jul 16;7(7). pii: bio035121. doi: 10.1242/bio.035121.


Energy cost and lower leg muscle activities during erect bipedal locomotion under hyperoxia.

Abe D, Fukuoka Y, Maeda T, Horiuchi M.

J Physiol Anthropol. 2018 Jun 19;37(1):18. doi: 10.1186/s40101-018-0177-7.


The Marmoset as an Animal Model of Influenza: Infection With A(H1N1)pdm09 and Highly Pathogenic A(H5N1) Viruses via the Conventional or Tracheal Spray Route.

Iwatsuki-Horimoto K, Nakajima N, Kiso M, Takahashi K, Ito M, Inoue T, Horiuchi M, Okahara N, Sasaki E, Hasegawa H, Kawaoka Y.

Front Microbiol. 2018 May 9;9:844. doi: 10.3389/fmicb.2018.00844. eCollection 2018.


[A Clinical Pathway Based on Medical and Nursing Teamwork in Drug Management Facilitates Integrated Community Care for Elderly Patients with Chronic Heart Failure].

Watanabe N, Morikawa G, Kubota K, Okazawa K, Tanaka C, Horiuchi M.

Yakugaku Zasshi. 2018;138(6):797-806. doi: 10.1248/yakushi.17-00209-4. Review. Japanese.


Impact of Sleeping Altitude on Symptoms of Acute Mountain Sickness on Mt. Fuji.

Horiuchi M, Uno T, Endo J, Handa Y, Hasegawa T.

High Alt Med Biol. 2018 Jun;19(2):193-200. doi: 10.1089/ham.2017.0106. Epub 2018 May 9.


Recognition of early stage thigmotaxis in Morris water maze test with convolutional neural network.

Higaki A, Mogi M, Iwanami J, Min LJ, Bai HY, Shan BS, Kan-No H, Ikeda S, Higaki J, Horiuchi M.

PLoS One. 2018 May 3;13(5):e0197003. doi: 10.1371/journal.pone.0197003. eCollection 2018.


Diurnal Variation of Melatonin Concentration in the Cerebrospinal Fluid of Unanesthetized Microminipig.

Abe M, Kawaguchi H, Miura N, Akioka K, Ushikai M, Oi S, Yukawa A, Yoshikawa T, Izumi H, Horiuchi M.

In Vivo. 2018 May-Jun;32(3):583-590.


[Long-term remission with mogamulizumab monotherapy in a patient with refractory adult T-cell leukemia-lymphoma].

Nakaya Y, Tsutsumi M, Fuseya H, Horiuchi M, Yoshimura T, Hayashi Y, Kanashima H, Nakao T, Yamane T.

Rinsho Ketsueki. 2018;59(3):326-328. doi: 10.11406/rinketsu.59.326. Japanese.


Semi-Automated Biomarker Discovery from Pharmacodynamic Effects on EEG in ADHD Rodent Models.

Yokota T, Struzik ZR, Jurica P, Horiuchi M, Hiroyama S, Li J, Takahara Y, Ogawa K, Nishitomi K, Hasegawa M, Cichocki A.

Sci Rep. 2018 Mar 26;8(1):5202. doi: 10.1038/s41598-018-23450-y.


Correlation between the 24-h urinary angiotensinogen or aldosterone level and muscle mass: Japan shimanami health promoting program study.

Mogi M, Kohara K, Tabara Y, Tsukuda K, Igase M, Horiuchi M.

Hypertens Res. 2018 May;41(5):326-333. doi: 10.1038/s41440-018-0021-9. Epub 2018 Mar 9.


Effects of Diets with Different Proportions of Protein/Carbohydrate on Retinal Manifestations in db Mice.

Arimura E, Okatani H, Araki T, Ushikai M, Nakakuma M, Abe M, Kawaguchi H, Izumi H, Horiuchi M.

In Vivo. 2018 Mar-Apr;32(2):265-272.


Protection of Differentiating Neuronal Cells from Amyloid β Peptide-induced Injury by Alkaline Extract of Leaves of Sasa senanensis Rehder.

Sakagami H, Tsuji M, Tomomura M, Masuda Y, Iwama S, Nakagawa M, Suzuki H, Tanaka K, Abe T, Tamura N, Tomomura A, Yokose S, Takeshima H, Natori T, Horiuchi M, Fujisawa T, Kiuchi Y, Oguchi K, Yasui T, Oizumi H, Oizumi T.

In Vivo. 2018 Mar-Apr;32(2):231-239.


Beneficial Effect of Mas Receptor Deficiency on Vascular Cognitive Impairment in the Presence of Angiotensin II Type 2 Receptor.

Higaki A, Mogi M, Iwanami J, Min LJ, Bai HY, Shan BS, Kukida M, Yamauchi T, Tsukuda K, Kan-No H, Ikeda S, Higaki J, Horiuchi M.

J Am Heart Assoc. 2018 Feb 3;7(3). pii: e008121. doi: 10.1161/JAHA.117.008121.


Predicting outcome of Morris water maze test in vascular dementia mouse model with deep learning.

Higaki A, Mogi M, Iwanami J, Min LJ, Bai HY, Shan BS, Kukida M, Kan-No H, Ikeda S, Higaki J, Horiuchi M.

PLoS One. 2018 Feb 7;13(2):e0191708. doi: 10.1371/journal.pone.0191708. eCollection 2018.


Combining behavior and EEG analysis for exploration of dynamic effects of ADHD treatment in animal models.

Jurica P, Struzik ZR, Li J, Horiuchi M, Hiroyama S, Takahara Y, Nishitomi K, Ogawa K, Cichocki A.

J Neurosci Methods. 2018 Mar 15;298:24-32. doi: 10.1016/j.jneumeth.2018.01.002. Epub 2018 Jan 31.


Insufficient sleep syndrome: An unrecognized but important clinical entity.

Kohyama J, Anzai Y, Ono M, Kishino A, Tamanuki K, Takada K, Inoue K, Horiuchi M, Hatai Y.

Pediatr Int. 2018 Apr;60(4):372-375. doi: 10.1111/ped.13519. Epub 2018 Feb 28.


Roles of angiotensin II type 2 receptor in mice with fetal growth restriction.

Yamauchi T, Mogi M, Kan-No H, Shan BS, Higaki A, Min LJ, Higaki T, Iwanami J, Ishii EI, Horiuchi M.

Hypertens Res. 2018 Mar;41(3):157-164. doi: 10.1038/s41440-017-0004-2. Epub 2018 Jan 15.


Barometric pressure change and heart rate response during sleeping at ~ 3000 m altitude.

Horiuchi M, Endo J, Handa Y, Nose H.

Int J Biometeorol. 2018 May;62(5):909-912. doi: 10.1007/s00484-017-1487-x. Epub 2017 Dec 27.


Effects of Dietary and Lighting Conditions on Diurnal Locomotor Activity and Body Temperature in Microminipigs.

Takeishi K, Kawaguchi H, Akioka K, Noguchi M, Arimura E, Abe M, Ushikai M, Okita S, Tanimoto A, Horiuchi M.

In Vivo. 2018 Jan-Feb;32(1):55-62.


Potential predictors of susceptibility to occupational stress in Japanese novice nurses - a pilot study.

Okita S, Daitoku S, Abe M, Arimura E, Setoyama H, Koriyama C, Ushikai M, Kawaguchi H, Horiuchi M.

Environ Health Prev Med. 2017 Apr 4;22(1):20. doi: 10.1186/s12199-017-0641-8.


Muscle oxygenation profiles between active and inactive muscles with nitrate supplementation under hypoxic exercise.

Horiuchi M, Endo J, Dobashi S, Handa Y, Kiuchi M, Koyama K.

Physiol Rep. 2017 Nov;5(20). pii: e13475. doi: 10.14814/phy2.13475.


Flow Cytometric Detection of PrPSc in Neurons and Glial Cells from Prion-Infected Mouse Brains.

Yamasaki T, Suzuki A, Hasebe R, Horiuchi M.

J Virol. 2017 Dec 14;92(1). pii: e01457-17. doi: 10.1128/JVI.01457-17. Print 2018 Jan 1.


Branched-chain amino acid supplementation restores reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats.

Horiuchi M, Takeda T, Takanashi H, Ozaki-Masuzawa Y, Taguchi Y, Toyoshima Y, Otani L, Kato H, Sone-Yonezawa M, Hakuno F, Takahashi SI, Takenaka A.

Nutr Metab (Lond). 2017 Sep 15;14:59. doi: 10.1186/s12986-017-0215-1. eCollection 2017.


Therapeutic effect of autologous compact bone-derived mesenchymal stem cell transplantation on prion disease.

Shan Z, Hirai Y, Nakayama M, Hayashi R, Yamasaki T, Hasebe R, Song CH, Horiuchi M.

J Gen Virol. 2017 Sep 6. doi: 10.1099/jgv.0.000907. [Epub ahead of print]


Peripheral T-cell lymphoma, not otherwise specified accompanied by central nervous system involvement with features of lymphomatosis cerebri.

Fuseya H, Nakao T, Hashimura M, Horiuchi M, Hayashi Y, Hagihara K, Kanashima H, Okuno T, Fukushima H, Inoue T, Manabe T, Yamane T.

Rinsho Ketsueki. 2017;58(7):760-765. doi: 10.11406/rinketsu.58.760. Japanese.


Impact of Carbohydrate-Electrolyte Beverage Ingestion on Heart Rate Response While Climbing Mountain Fuji at ~3000 m.

Horiuchi M, Endo J, Kondo K, Uno T, Morikawa M, Nose H.

Biomed Res Int. 2017;2017:3919826. doi: 10.1155/2017/3919826. Epub 2017 Jul 10.


Deficiency of angiotensin-converting enzyme 2 causes deterioration of cognitive function.

Wang XL, Iwanami J, Min LJ, Tsukuda K, Nakaoka H, Bai HY, Shan BS, Kan-No H, Kukida M, Chisaka T, Yamauchi T, Higaki A, Mogi M, Horiuchi M.

NPJ Aging Mech Dis. 2016 Oct 20;2:16024. doi: 10.1038/npjamd.2016.24. eCollection 2016.


Management Effectiveness of a Secondary Coniferous Forest for Landscape Appreciation and Psychological Restoration.

Takayama N, Fujiwara A, Saito H, Horiuchi M.

Int J Environ Res Public Health. 2017 Jul 18;14(7). pii: E800. doi: 10.3390/ijerph14070800.


Measuring the Energy of Ventilation and Circulation during Human Walking using Induced Hypoxia.

Horiuchi M, Fukuoka Y, Handa Y, Abe D, Pontzer H.

Sci Rep. 2017 Jul 10;7(1):4938. doi: 10.1038/s41598-017-05068-8.


Protein tyrosine phosphatase σ regulates autoimmune encephalomyelitis development.

Ohtake Y, Kong W, Hussain R, Horiuchi M, Tremblay ML, Ganea D, Li S.

Brain Behav Immun. 2017 Oct;65:111-124. doi: 10.1016/j.bbi.2017.05.018. Epub 2017 May 27.


Differing intrinsic biological properties between forebrain and spinal oligodendroglial lineage cells.

Horiuchi M, Suzuki-Horiuchi Y, Akiyama T, Itoh A, Pleasure D, Carstens E, Itoh T.

J Neurochem. 2017 Aug;142(3):378-391. doi: 10.1111/jnc.14074. Epub 2017 Jun 9.


Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS.

Leonhardt J, Villela DC, Teichmann A, Münter LM, Mayer MC, Mardahl M, Kirsch S, Namsolleck P, Lucht K, Benz V, Alenina N, Daniell N, Horiuchi M, Iwai M, Multhaup G, Schülein R, Bader M, Santos RA, Unger T, Steckelings UM.

Hypertension. 2017 Jun;69(6):1128-1135. doi: 10.1161/HYPERTENSIONAHA.116.08814. Epub 2017 May 1.


Quantitative Potassium Measurements with Laser-Induced Breakdown Spectroscopy Using Low-Energy Lasers: Application to In Situ K-Ar Geochronology for Planetary Exploration.

Cho Y, Horiuchi M, Shibasaki K, Kameda S, Sugita S.

Appl Spectrosc. 2017 Aug;71(8):1969-1981. doi: 10.1177/0003702817701941. Epub 2017 Apr 27.


Listeria monocytogenes serotype 4b strains replicate in monocytes/macrophages more than the other serotypes.

Hasebe R, Nakao R, Ohnuma A, Yamasaki T, Sawa H, Takai S, Horiuchi M.

J Vet Med Sci. 2017 Jun 10;79(6):962-969. doi: 10.1292/jvms.16-0575. Epub 2017 Apr 17.


Effects of Short-Term Acclimatization at the Summit of Mt. Fuji (3776 m) on Sleep Efficacy, Cardiovascular Responses, and Ventilatory Responses.

Horiuchi M, Oda S, Uno T, Endo J, Handa Y, Fukuoka Y.

High Alt Med Biol. 2017 Jun;18(2):171-178. doi: 10.1089/ham.2016.0162. Epub 2017 Apr 4.


Muscle activities during walking and running at energetically optimal transition speed under normobaric hypoxia on gradient slopes.

Abe D, Fukuoka Y, Horiuchi M.

PLoS One. 2017 Mar 16;12(3):e0173816. doi: 10.1371/journal.pone.0173816. eCollection 2017.


Arm-Cranking Exercise Training Reduces Plasminogen Activator Inhibitor 1 in People With Spinal Cord Injury.

Horiuchi M, Okita K.

Arch Phys Med Rehabil. 2017 Nov;98(11):2174-2180. doi: 10.1016/j.apmr.2017.02.007. Epub 2017 Mar 10.



Horiuchi M, Subudhi AW.

Exp Physiol. 2017 Mar 1;102(3):384. doi: 10.1113/EP086243. No abstract available.


Administration of bovine casein-derived peptide prevents cognitive decline in Alzheimer disease model mice.

Min LJ, Kobayashi Y, Mogi M, Tsukuda K, Yamada A, Yamauchi K, Abe F, Iwanami J, Xiao JZ, Horiuchi M.

PLoS One. 2017 Feb 3;12(2):e0171515. doi: 10.1371/journal.pone.0171515. eCollection 2017.


Enhancement of Adipocyte Browning by Angiotensin II Type 1 Receptor Blockade.

Tsukuda K, Mogi M, Iwanami J, Kanno H, Nakaoka H, Wang XL, Bai HY, Shan BS, Kukida M, Higaki A, Yamauchi T, Min LJ, Horiuchi M.

PLoS One. 2016 Dec 19;11(12):e0167704. doi: 10.1371/journal.pone.0167704. eCollection 2016.


Birth of Cloned Microminipigs Derived from Somatic Cell Nuclear Transfer Embryos That Have Been Transiently Treated with Valproic Acid.

Miyoshi K, Kawaguchi H, Maeda K, Sato M, Akioka K, Noguchi M, Horiuchi M, Tanimoto A.

Cell Reprogram. 2016 Nov;18(6):390-400.


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