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Items: 1 to 50 of 190

1.

The relationship between tumour glucose metabolism and host systemic inflammatory responses in patients with cancer: A systematic review.

Dolan RD, McLees NG, Irfan A, McSorley ST, Horgan PG, Colville D, McMillan DC.

J Nucl Med. 2018 Aug 30. pii: jnumed.118.216697. doi: 10.2967/jnumed.118.216697. [Epub ahead of print]

PMID:
30166353
2.

A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer.

Roseweir AK, Kong CY, Park JH, Bennett L, Powell AGMT, Quinn J, van Wyk HC, Horgan PG, McMillan DC, Edwards J, Roxburgh CS.

Int J Cancer. 2018 Jul 11. doi: 10.1002/ijc.31739. [Epub ahead of print]

PMID:
29992570
3.

ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer.

Roseweir AK, Halcrow ES, Chichilo S, Powell AG, McMillan DC, Horgan PG, Edwards J.

Br J Cancer. 2018 Jul 10. doi: 10.1038/s41416-018-0174-y. [Epub ahead of print]

PMID:
29988110
4.

The relationship between cardiopulmonary exercise test variables, the systemic inflammatory response, and complications following surgery for colorectal cancer.

McSorley ST, Roxburgh CSD, Horgan PG, McMillan DC.

Perioper Med (Lond). 2018 Jun 15;7:11. doi: 10.1186/s13741-018-0093-8. eCollection 2018.

5.

Predictive Biomarkers for Endocrine Therapy: Retrospective Study in Tamoxifen and Exemestane Adjuvant Multinational (TEAM) Trial.

Roseweir AK, Bennett L, Dickson A, Cheng K, Quintayo MA, Bayani J, McMillan DC, Horgan PG, van de Velde CJH, Seynaeve C, Hasenburg A, Kieback DG, Markopoulos C, Dirix LY, Rea DW, Mallon EA, Bartlett JMS, Edwards J.

J Natl Cancer Inst. 2018 Jun 1;110(6):616-627. doi: 10.1093/jnci/djx255.

PMID:
29917140
6.

The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores.

Dolan RD, McSorley ST, Park JH, Watt DG, Roxburgh CS, Horgan PG, McMillan DC.

Br J Cancer. 2018 Jul;119(1):40-51. doi: 10.1038/s41416-018-0095-9. Epub 2018 May 23.

PMID:
29789606
7.

Determinants of lymph node count and positivity in patients undergoing surgery for colon cancer.

Dolan RD, McSorley ST, Horgan PG, McMillan DC.

Medicine (Baltimore). 2018 Mar;97(13):e0185. doi: 10.1097/MD.0000000000010185.

8.

Factors associated with the efficacy of polyp detection during routine flexible sigmoidoscopy.

Maliampurakal AJ, McMillan DC, Anderson JH, Horgan PG, Mansouri D.

Frontline Gastroenterol. 2018 Apr;9(2):135-142. doi: 10.1136/flgastro-2017-100849. Epub 2017 Aug 26.

PMID:
29588842
9.

NF-κB pathways in the development and progression of colorectal cancer.

Patel M, Horgan PG, McMillan DC, Edwards J.

Transl Res. 2018 Jul;197:43-56. doi: 10.1016/j.trsl.2018.02.002. Epub 2018 Mar 1. Review.

PMID:
29550444
10.

The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer.

Patel M, McSorley ST, Park JH, Roxburgh CSD, Edwards J, Horgan PG, McMillan DC.

Br J Cancer. 2018 Mar 6;118(5):705-712. doi: 10.1038/bjc.2017.441. Epub 2018 Jan 16.

PMID:
29337962
11.

The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis.

Dolan RD, Lim J, McSorley ST, Horgan PG, McMillan DC.

Sci Rep. 2017 Dec 1;7(1):16717. doi: 10.1038/s41598-017-16955-5.

12.

The relationship between 18 F-FDG-PETCT-derived markers of tumour metabolism and systemic inflammation in patients with recurrent disease following surgery for colorectal cancer.

McSorley ST, Khor BY, Tsang K, Colville D, Han S, Horgan PG, McMillan DC.

Colorectal Dis. 2018 May;20(5):407-415. doi: 10.1111/codi.13973.

PMID:
29178362
13.

Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer.

Park JH, Ishizuka M, McSorley ST, Kubota K, Roxburgh CSD, Nagata H, Takagi K, Iwasaki Y, Aoki T, Horgan PG, McMillan DC.

Am J Surg. 2018 Sep;216(3):458-464. doi: 10.1016/j.amjsurg.2017.08.044. Epub 2017 Sep 20.

PMID:
28967380
14.

Attitudes of surgeons to the use of postoperative markers of the systemic inflammatory response following elective surgery.

Dolan RD, McSorley ST, McMillan DC, Horgan PG.

Ann Med Surg (Lond). 2017 Jul 20;21:14-19. doi: 10.1016/j.amsu.2017.07.046. eCollection 2017 Sep.

15.

Clinicopathological Determinants of an Elevated Systemic Inflammatory Response Following Elective Potentially Curative Resection for Colorectal Cancer.

Watt DG, Ramanathan ML, McSorley ST, Walley K, Park JH, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Sep;24(9):2588-2594. doi: 10.1245/s10434-017-5987-z. Epub 2017 Jul 10.

16.

The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta-analysis.

Dolan RD, McSorley ST, Horgan PG, Laird B, McMillan DC.

Crit Rev Oncol Hematol. 2017 Aug;116:134-146. doi: 10.1016/j.critrevonc.2017.06.002. Epub 2017 Jun 9. Review.

PMID:
28693795
17.

The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer.

McSorley ST, Black DH, Horgan PG, McMillan DC.

Clin Nutr. 2018 Aug;37(4):1279-1285. doi: 10.1016/j.clnu.2017.05.017. Epub 2017 May 19.

PMID:
28566220
18.

Colorectal cancer subtypes: Translation to routine clinical pathology.

Roseweir AK, McMillan DC, Horgan PG, Edwards J.

Cancer Treat Rev. 2017 Jun;57:1-7. doi: 10.1016/j.ctrv.2017.04.006. Epub 2017 May 4. Review.

PMID:
28505475
19.

Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer.

Park JH, van Wyk H, Roxburgh CSD, Horgan PG, Edwards J, McMillan DC.

Br J Cancer. 2017 May 23;116(11):1444-1450. doi: 10.1038/bjc.2017.108. Epub 2017 Apr 20.

20.

The relationship between members of the canonical NF-κB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer.

Bennett L, Mallon EA, Horgan PG, Paul A, McMillan DC, Edwards J.

Oncotarget. 2017 May 16;8(20):33002-33013. doi: 10.18632/oncotarget.16031.

21.

The Impact of Preoperative Dexamethasone on the Magnitude of the Postoperative Systemic Inflammatory Response and Complications Following Surgery for Colorectal Cancer.

McSorley ST, Roxburgh CSD, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Aug;24(8):2104-2112. doi: 10.1245/s10434-017-5817-3. Epub 2017 Mar 1.

22.

In reply to 'Hynes et al. Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population-based study'.

Park JH, Roxburgh CSD, Edwards J, Horgan PG, McMillan DC.

Histopathology. 2017 Aug;71(2):326-327. doi: 10.1111/his.13195. Epub 2017 Apr 12. No abstract available.

PMID:
28226191
23.

Examination of a CRP first approach for the detection of postoperative complications in patients undergoing surgery for colorectal cancer: A pragmatic study.

McSorley ST, Khor BY, MacKay GJ, Horgan PG, McMillan DC.

Medicine (Baltimore). 2017 Feb;96(7):e6133. doi: 10.1097/MD.0000000000006133.

24.

In reply to: "Meyer CP et al., The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures".

Park JH, Horgan PG, McMillan DC.

Am J Surg. 2018 Jul;216(1):174-175. doi: 10.1016/j.amjsurg.2016.12.023. Epub 2017 Jan 2. No abstract available.

PMID:
28082008
25.

High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer.

Bennett L, Quinn J, McCall P, Mallon EA, Horgan PG, McMillan DC, Paul A, Edwards J.

Int J Cancer. 2017 Apr 1;140(7):1633-1644. doi: 10.1002/ijc.30578. Epub 2017 Jan 6.

26.

The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: A cross-sectional study.

Khor BY, McSorley ST, Horgan PG, McMillan DC.

Int J Surg. 2017 Jan;37:79-84. doi: 10.1016/j.ijsu.2016.12.010. Epub 2016 Dec 9.

PMID:
27940290
27.

The Pretreatment Systemic Inflammatory Response is an Important Determinant of Poor Pathologic Response for Patients Undergoing Neoadjuvant Therapy for Rectal Cancer.

Dreyer SB, Powell AG, McSorley ST, Waterston A, Going JJ, Edwards J, McMillan DC, Horgan PG.

Ann Surg Oncol. 2017 May;24(5):1295-1303. doi: 10.1245/s10434-016-5684-3. Epub 2016 Nov 21.

28.

A Postoperative Systemic Inflammation Score Predicts Short- and Long-Term Outcomes in Patients Undergoing Surgery for Colorectal Cancer.

Watt DG, McSorley ST, Park JH, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Apr;24(4):1100-1109. doi: 10.1245/s10434-016-5659-4. Epub 2016 Nov 7.

PMID:
27822634
29.

Comment on "The Important Role for Intravenous Iron in Perioperative Patient Blood Management in Major Abdominal Surgery: A Randomized Controlled Trial".

McSorley ST, Mansouri D, Horgan PG, McMillan DC.

Ann Surg. 2018 Mar;267(3):e49. doi: 10.1097/SLA.0000000000002053. No abstract available.

PMID:
27759622
30.

Signal Transduction and Activator of Transcription-3 (STAT3) in Patients with Colorectal Cancer: Associations with the Phenotypic Features of the Tumor and Host.

Park JH, van Wyk H, McMillan DC, Quinn J, Clark J, Roxburgh CS, Horgan PG, Edwards J.

Clin Cancer Res. 2017 Apr 1;23(7):1698-1709. doi: 10.1158/1078-0432.CCR-16-1416. Epub 2016 Sep 27.

31.

Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer.

Roseweir AK, Powell AG, Bennett L, Van Wyk HC, Park J, McMillan DC, Horgan PG, Edwards J.

Oncotarget. 2016 Oct 25;7(43):70601-70612. doi: 10.18632/oncotarget.12134.

32.

The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer.

van Wyk HC, Park JH, Edwards J, Horgan PG, McMillan DC, Going JJ.

Br J Cancer. 2016 Jul 12;115(2):156-63. doi: 10.1038/bjc.2016.173. Epub 2016 Jun 14.

33.

Comparison of the prognostic value of measures of the tumor inflammatory cell infiltrate and tumor-associated stroma in patients with primary operable colorectal cancer.

Park JH, McMillan DC, Edwards J, Horgan PG, Roxburgh CS.

Oncoimmunology. 2016 Mar 21;5(3):e1098801. eCollection 2016 Mar.

34.

Postoperative Systemic Inflammatory Response, Complication Severity, and Survival Following Surgery for Colorectal Cancer.

McSorley ST, Watt DG, Horgan PG, McMillan DC.

Ann Surg Oncol. 2016 Sep;23(9):2832-40. doi: 10.1245/s10434-016-5204-5. Epub 2016 Mar 25.

35.

The impact of preoperative corticosteroids on the systemic inflammatory response and postoperative complications following surgery for gastrointestinal cancer: A systematic review and meta-analysis.

McSorley ST, Horgan PG, McMillan DC.

Crit Rev Oncol Hematol. 2016 May;101:139-50. doi: 10.1016/j.critrevonc.2016.03.011. Epub 2016 Mar 10. Review.

PMID:
26997303
36.

Long-Term Follow-Up of Patients Undergoing Resection of TNM Stage I Colorectal Cancer: An Analysis of Tumour and Host Determinants of Outcome.

Mansouri D, Powell AG, Park JH, McMillan DC, Horgan PG.

World J Surg. 2016 Jun;40(6):1485-91. doi: 10.1007/s00268-016-3443-z.

PMID:
26920405
37.

Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment.

Park JH, Powell AG, Roxburgh CS, Horgan PG, McMillan DC, Edwards J.

Br J Cancer. 2016 Mar 1;114(5):562-70. doi: 10.1038/bjc.2016.17. Epub 2016 Feb 9.

38.

A comparison of tumour and host prognostic factors in screen-detected vs nonscreen-detected colorectal cancer: a contemporaneous study.

Mansouri D, McMillan DC, McIlveen E, Crighton EM, Morrison DS, Horgan PG.

Colorectal Dis. 2016 Oct;18(10):967-975. doi: 10.1111/codi.13295.

PMID:
26859503
39.

Comparison of Methods to Identify Lymphatic and Blood Vessel Invasion and their Prognostic Value in Patients with Primary Operable Colorectal Cancer.

Van Wyk HC, Foulis AK, Roxburgh CS, Orange C, Horgan PG, McMillan DC.

Anticancer Res. 2015 Dec;35(12):6457-63.

PMID:
26637856
40.

The Neutrophil-Platelet Score (NPS) Predicts Survival in Primary Operable Colorectal Cancer and a Variety of Common Cancers.

Watt DG, Proctor MJ, Park JH, Horgan PG, McMillan DC.

PLoS One. 2015 Nov 6;10(11):e0142159. doi: 10.1371/journal.pone.0142159. eCollection 2015.

41.

A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer.

Watt DG, Roxburgh CS, White M, Chan JZ, Horgan PG, McMillan DC.

Mediators Inflamm. 2015;2015:842070. doi: 10.1155/2015/842070. Epub 2015 Oct 4.

42.

Enhanced Recovery After Surgery: Which Components, If Any, Impact on The Systemic Inflammatory Response Following Colorectal Surgery?: A Systematic Review.

Watt DG, McSorley ST, Horgan PG, McMillan DC.

Medicine (Baltimore). 2015 Sep;94(36):e1286. doi: 10.1097/MD.0000000000001286.

43.

The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: A systematic review and meta-analysis.

McSorley ST, Horgan PG, McMillan DC.

Crit Rev Oncol Hematol. 2016 Jan;97:168-77. doi: 10.1016/j.critrevonc.2015.08.013. Epub 2015 Aug 14. Review.

PMID:
26330375
44.

RE: nab-Paclitaxel Plus Gemcitabine for Metastatic Pancreatic Cancer: Long-Term Survival From a Phase III Trial.

Palani Velu LK, Steele CW, Dickson EJ, Carter CR, McKay CJ, Horgan PG, McMillan DC, Jamieson NB.

J Natl Cancer Inst. 2015 Aug 6;107(9). pii: djv204. doi: 10.1093/jnci/djv204. Print 2015 Sep. No abstract available.

45.

Temporal trends in mode, site and stage of presentation with the introduction of colorectal cancer screening: a decade of experience from the West of Scotland.

Mansouri D, McMillan DC, Crearie C, Morrison DS, Crighton EM, Horgan PG.

Br J Cancer. 2015 Jul 28;113(3):556-61. doi: 10.1038/bjc.2015.230. Epub 2015 Jul 9.

46.

The role of dietary polyphenols in the moderation of the inflammatory response in early stage colorectal cancer.

Little CH, Combet E, McMillan DC, Horgan PG, Roxburgh CS.

Crit Rev Food Sci Nutr. 2017 Jul 24;57(11):2310-2320. doi: 10.1080/10408398.2014.997866. Review.

PMID:
26066365
47.

Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer.

McSorley ST, Ramanathan ML, Horgan PG, McMillan DC.

Int J Colorectal Dis. 2015 Jul;30(7):913-7. doi: 10.1007/s00384-015-2229-3. Epub 2015 Apr 29.

PMID:
25922147
48.

Comment on "prognostic performance of inflammation-based prognostic indices in patients with resectable colorectal liver metastases".

Watt DG, Horgan PG, McMillan DC.

Med Oncol. 2015 May;32(5):167. doi: 10.1007/s12032-015-0617-8. Epub 2015 Apr 23. No abstract available.

PMID:
25904501
49.

Neutrophil count is the most important prognostic component of the differential white cell count in patients undergoing elective surgery for colorectal cancer.

Watt DG, Martin JC, Park JH, Horgan PG, McMillan DC.

Am J Surg. 2015 Jul;210(1):24-30. doi: 10.1016/j.amjsurg.2014.12.031. Epub 2015 Mar 12.

PMID:
25842358
50.

Systemic inflammation predicts all-cause mortality: a glasgow inflammation outcome study.

Proctor MJ, McMillan DC, Horgan PG, Fletcher CD, Talwar D, Morrison DS.

PLoS One. 2015 Mar 2;10(3):e0116206. doi: 10.1371/journal.pone.0116206. eCollection 2015.

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