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Response to Olaparib in a PALB2 Germline Mutated Prostate Cancer and Genetic Events Associated with Resistance.

Horak P, Weischenfeldt J, von Amsberg G, Beyer B, Schutte A, Uhrig S, Gieldon L, Klink B, Feuerbach L, Hubschmann D, Kreutzfeldt S, Heining C, Maier S, Hutter B, Penzel R, Schlesner M, Eils R, Sauter G, Stenzinger A, Brors B, Schröck E, Glimm H, Fröhling S, Schlomm T.

Cold Spring Harb Mol Case Stud. 2019 Mar 4. pii: mcs.a003657. doi: 10.1101/mcs.a003657. [Epub ahead of print]


Molecular evidence for distinct modes of nutrient acquisition between visceral and neurotropic schistosomes of birds.

Leontovyč R, Young ND, Korhonen PK, Hall RS, Bulantová J, Jeřábková V, Kašný M, Gasser RB, Horák P.

Sci Rep. 2019 Feb 4;9(1):1347. doi: 10.1038/s41598-018-37669-2.


Real world use of secukinumab for treatment of axial spondyloarthritis and psoriatic arthritis: nationwide results from the ATTRA registry.

Mann HF, Závada J, Šenolt L, Bubová K, Nekvindová L, Křístková Z, Horák P, Vencovský J, Pavelka K; and the ATTRA Registry.

Clin Exp Rheumatol. 2019 Jan 4. [Epub ahead of print] No abstract available.


Synthetic lethal combinations of low-toxicity drugs for breast cancer identified in silico by genetic screens in yeast.

Marhold M, Tomasich E, Schwarz M, Udovica S, Heinzel A, Mayer P, Horak P, Perco P, Krainer M.

Oncotarget. 2018 Nov 20;9(91):36379-36391. doi: 10.18632/oncotarget.26372. eCollection 2018 Nov 20.


Uropygial gland size: a marker of phenotypic quality that shows no senescence in a long-lived seabird.

Urvik J, Rattiste K, Hõrak P, Meitern R, Sepp T.

Biogerontology. 2019 Apr;20(2):141-148. doi: 10.1007/s10522-018-9782-4. Epub 2018 Nov 10.


Demographic and evolutionary trends in ovarian function and aging.

Laisk T, Tšuiko O, Jatsenko T, Hõrak P, Otala M, Lahdenperä M, Lummaa V, Tuuri T, Salumets A, Tapanainen JS.

Hum Reprod Update. 2019 Jan 1;25(1):34-50. doi: 10.1093/humupd/dmy031.


Cercarial dermatitis: a systematic follow-up study of human cases with implications for diagnostics.

Macháček T, Turjanicová L, Bulantová J, Hrdý J, Horák P, Mikeš L.

Parasitol Res. 2018 Dec;117(12):3881-3895. doi: 10.1007/s00436-018-6095-0. Epub 2018 Oct 9.


Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.

Réda J, Vachtenheim J, Vlčková K, Horák P, Vachtenheim J Jr, Ondrušová L.

Int J Mol Sci. 2018 Sep 10;19(9). pii: E2682. doi: 10.3390/ijms19092682.


Impact of trematode infections on periphyton grazing rates of freshwater snails.

Vivas Muñoz JC, Hilt S, Horák P, Knopf K.

Parasitol Res. 2018 Nov;117(11):3547-3555. doi: 10.1007/s00436-018-6052-y. Epub 2018 Sep 1.


Frequency-banded nonlinear Schrödinger equation with inclusion of Raman nonlinearity.

Begleris I, Horak P.

Opt Express. 2018 Aug 20;26(17):21527-21536. doi: 10.1364/OE.26.021527.


Prospective Use of High-Refractive Index Materials for Single Molecule Detection in Flow Cytometry.

Welsh JA, Kepley J, Rosner A, Horak P, Berzofsky JA, Jones JC.

Sensors (Basel). 2018 Aug 1;18(8). pii: E2461. doi: 10.3390/s18082461.


Age-specific patterns of maternal investment in common gull egg yolk.

Urvik J, Rattiste K, Giraudeau M, Okuliarová M, Hõrak P, Sepp T.

Biol Lett. 2018 Jul;14(7). pii: 20180346. doi: 10.1098/rsbl.2018.0346.


Potamopyrgus antipodarum as a potential defender against swimmer's itch in European recreational water bodies-experimental study.

Marszewska A, Cichy A, Bulantová J, Horák P, Żbikowska E.

PeerJ. 2018 Jun 25;6:e5045. doi: 10.7717/peerj.5045. eCollection 2018.


NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer.

Heining C, Horak P, Uhrig S, Codo PL, Klink B, Hutter B, Fröhlich M, Bonekamp D, Richter D, Steiger K, Penzel R, Endris V, Ehrenberg KR, Frank S, Kleinheinz K, Toprak UH, Schlesner M, Mandal R, Schulz L, Lambertz H, Fetscher S, Bitzer M, Malek NP, Horger M, Giese NA, Strobel O, Hackert T, Springfeld C, Feuerbach L, Bergmann F, Schröck E, von Kalle C, Weichert W, Scholl C, Ball CR, Stenzinger A, Brors B, Fröhling S, Glimm H.

Cancer Discov. 2018 Sep;8(9):1087-1095. doi: 10.1158/2159-8290.CD-18-0036. Epub 2018 May 25.


Enabling Stroke Rehabilitation in Home and Community Settings: A Wearable Sensor-Based Approach for Upper-Limb Motor Training.

Lee SI, Adans-Dester CP, Grimaldi M, Dowling AV, Horak PC, Black-Schaffer RM, Bonato P, Gwin JT.

IEEE J Transl Eng Health Med. 2018 May 2;6:2100411. doi: 10.1109/JTEHM.2018.2829208. eCollection 2018.


Nonlinear dynamic of picosecond pulse propagation in atmospheric air-filled hollow core fibers.

Mousavi SA, Mulvad HCH, Wheeler NV, Horak P, Hayes J, Chen Y, Bradley TD, Alam SU, Sandoghchi SR, Fokoua EN, Richardson DJ, Poletti F.

Opt Express. 2018 Apr 2;26(7):8866-8882. doi: 10.1364/OE.26.008866.


[Life threatening manifestations of lupus and antiphospholipid syndrome in internal medicine].

Horák P, Skácelová M, Vymětal J, Schubertová M.

Vnitr Lek. 2018 Spring;64(2):136-145. Czech.


Radiation Resistance of the U(Al, Si)₃ Alloy: Ion-Induced Disordering.

Meshi L, Yaniv G, Horak P, Vacik J, Mykytenko N, Rafailov G, Dahan I, Fuks D, Kiv A.

Materials (Basel). 2018 Feb 2;11(2). pii: E228. doi: 10.3390/ma11020228.


Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells.

Vlčková K, Vachtenheim J, Réda J, Horák P, Ondrušová L.

J Cell Mol Med. 2018 Apr;22(4):2240-2251. doi: 10.1111/jcmm.13506. Epub 2018 Jan 25.


Design and rationale of the Cardiovascular Health and Text Messaging (CHAT) Study and the CHAT-Diabetes Mellitus (CHAT-DM) Study: two randomised controlled trials of text messaging to improve secondary prevention for coronary heart disease and diabetes.

Huo X, Spatz ES, Ding Q, Horak P, Zheng X, Masters C, Zhang H, Irwin ML, Yan X, Guan W, Li J, Li X, Spertus JA, Masoudi FA, Krumholz HM, Jiang L.

BMJ Open. 2017 Dec 21;7(12):e018302. doi: 10.1136/bmjopen-2017-018302. Erratum in: BMJ Open. 2018 Jan 21;8(1):e018302corr1.


Extracellular trap-like fiber release may not be a prominent defence response in snails: evidence from three species of freshwater gastropod molluscs.

Skála V, Walker AJ, Horák P.

Dev Comp Immunol. 2018 Feb;79:137-141. doi: 10.1016/j.dci.2017.10.011. Epub 2017 Oct 22.


Humoral response of mice infected with Toxocara canis following different infection schemes.

Novák J, Panská L, Macháček T, Kolářová L, Horák P.

Acta Parasitol. 2017 Dec 20;62(4):823-835. doi: 10.1515/ap-2017-0099.


Genomics of Immunotherapy-Associated Hyperprogressors-Letter.

Forschner A, Niessner H, Möller Y, Horak P, Fröhlich M, Warsow G, Stenzinger A, Fröhling S, Glimm H, Klumpp B, Garbe C, Sinnberg T.

Clin Cancer Res. 2017 Oct 15;23(20):6374-6375. doi: 10.1158/1078-0432.CCR-17-1480. No abstract available.


Serum protein pattern associated with organ damage and lupus nephritis in systemic lupus erythematosus revealed by PEA immunoassay.

Petrackova A, Smrzova A, Gajdos P, Schubertova M, Schneiderova P, Kromer P, Snasel V, Skacelova M, Mrazek F, Zadrazil J, Horak P, Kriegova E.

Clin Proteomics. 2017 Oct 3;14:32. doi: 10.1186/s12014-017-9167-8. eCollection 2017.


TUSC3: functional duality of a cancer gene.

Vašíčková K, Horak P, Vaňhara P.

Cell Mol Life Sci. 2018 Mar;75(5):849-857. doi: 10.1007/s00018-017-2660-4. Epub 2017 Sep 19. Review.


[Personalized oncology].

Heining C, Horak P, Gröschel S, Glimm H, Fröhling S.

Radiologe. 2017 Oct;57(10):804-811. doi: 10.1007/s00117-017-0297-9. Review. German.


Fiber cavities with integrated mode matching optics.

Gulati GK, Takahashi H, Podoliak N, Horak P, Keller M.

Sci Rep. 2017 Jul 17;7(1):5556. doi: 10.1038/s41598-017-05729-8.


Precision oncology based on omics data: The NCT Heidelberg experience.

Horak P, Klink B, Heining C, Gröschel S, Hutter B, Fröhlich M, Uhrig S, Hübschmann D, Schlesner M, Eils R, Richter D, Pfütze K, Geörg C, Meißburger B, Wolf S, Schulz A, Penzel R, Herpel E, Kirchner M, Lier A, Endris V, Singer S, Schirmacher P, Weichert W, Stenzinger A, Schlenk RF, Schröck E, Brors B, von Kalle C, Glimm H, Fröhling S.

Int J Cancer. 2017 Sep 1;141(5):877-886. doi: 10.1002/ijc.30828. Epub 2017 Jun 21.


Higher levels of matrix metalloproteinase-3 in patients with RA reflect disease activity and structural damage.

Skacelova M, Hermanova Z, Horak P, Ahmed K, Langova K.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Sep;161(3):296-302. doi: 10.5507/bp.2017.015. Epub 2017 Apr 26.


Changes in surface glycosylation and glycocalyx shedding in Trichobilharzia regenti (Schistosomatidae) during the transformation of cercaria to schistosomulum.

Řimnáčová J, Mikeš L, Turjanicová L, Bulantová J, Horák P.

PLoS One. 2017 Mar 15;12(3):e0173217. doi: 10.1371/journal.pone.0173217. eCollection 2017.


Commentary: transgenerational effects of parental death-a life history perspective.

Hõrak P.

Int J Epidemiol. 2017 Feb 1;46(1):230-232. doi: 10.1093/ije/dyw368. No abstract available.


Inter-modal four-wave mixing study in a two-mode fiber.

Friis SM, Begleris I, Jung Y, Rottwitt K, Petropoulos P, Richardson DJ, Horak P, Parmigiani F.

Opt Express. 2016 Dec 26;24(26):30338-30349. doi: 10.1364/OE.24.030338.


Simple and noninvasive method for assessment of digestive efficiency: Validation of fecal steatocrit in greenfinch coccidiosis model.

Meitern R, Lind MA, Karu U, Hõrak P.

Ecol Evol. 2016 Nov 17;6(24):8756-8763. doi: 10.1002/ece3.2575. eCollection 2016 Dec.


Interictal epileptiform discharges impair word recall in multiple brain areas.

Horak PC, Meisenhelter S, Song Y, Testorf ME, Kahana MJ, Viles WD, Bujarski KA, Connolly AC, Robbins AA, Sperling MR, Sharan AD, Worrell GA, Miller LR, Gross RE, Davis KA, Roberts DW, Lega B, Sheth SA, Zaghloul KA, Stein JM, Das SR, Rizzuto DS, Jobst BC.

Epilepsia. 2017 Mar;58(3):373-380. doi: 10.1111/epi.13633. Epub 2016 Dec 9.


Integrating next-generation sequencing into clinical oncology: strategies, promises and pitfalls.

Horak P, Fröhling S, Glimm H.

ESMO Open. 2016 Nov 18;1(5):e000094. eCollection 2016. Review.


Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification.

Gröschel S, Bommer M, Hutter B, Budczies J, Bonekamp D, Heining C, Horak P, Fröhlich M, Uhrig S, Hübschmann D, Geörg C, Richter D, Pfarr N, Pfütze K, Wolf S, Schirmacher P, Jäger D, von Kalle C, Brors B, Glimm H, Weichert W, Stenzinger A, Fröhling S.

Cold Spring Harb Mol Case Stud. 2016 Nov;2(6):a001180.


Nitric oxide and cytokine production by glial cells exposed in vitro to neuropathogenic schistosome Trichobilharzia regenti.

Macháček T, Panská L, Dvořáková H, Horák P.

Parasit Vectors. 2016 Nov 14;9(1):579.


All-fiber fourth and fifth harmonic generation from a single source.

Khudus MI, Lee T, De Lucia F, Corbari C, Sazio P, Horak P, Brambilla G.

Opt Express. 2016 Sep 19;24(19):21777-93. doi: 10.1364/OE.24.021777.


Variation in the Markers of Nutritional and Oxidative State in a Long-Lived Seabird: Associations with Age and Longevity.

Urvik J, Meitern R, Rattiste K, Saks L, Hõrak P, Sepp T.

Physiol Biochem Zool. 2016 Sep-Oct;89(5):417-40. doi: 10.1086/688180. Epub 2016 Aug 15.


Historical analysis of the type species of the genus Trichobilharzia Skrjabin et Zakharov, 1920 (Platyhelminthes: Schistosomatidae).

Aldhoun J, Kment P, Horák P.

Zootaxa. 2016 Feb 29;4084(4):593-5. doi: 10.11646/zootaxa.4084.4.10.


[Double incision laparoscopic surgery].

Horák P, Janeček Z, Červinková M, Marvan J, Průchová V, Fanta J.

Rozhl Chir. Spring 2016;95(5):196-9. Czech.


Including sheath effects in the interpretation of planar retarding potential analyzer's low-energy ion data.

Fisher LE, Lynch KA, Fernandes PA, Bekkeng TA, Moen J, Zettergren M, Miceli RJ, Powell S, Lessard MR, Horak P.

Rev Sci Instrum. 2016 Apr;87(4):043504. doi: 10.1063/1.4944416.


Effect of Fascioloides magna (Digenea) on fecundity, shell height, and survival rate of Pseudosuccinea columella (Lymnaeidae).

Pankrác J, Novobilský A, Rondelaud D, Leontovyč R, Syrovátka V, Rajský D, Horák P, Kašný M.

Parasitol Res. 2016 Aug;115(8):3119-25. doi: 10.1007/s00436-016-5068-4. Epub 2016 Apr 21.


Corrigendum: Tunable continuous wave emission via phase-matched second harmonic generation in a ZnSe microcylindrical resonator.

Vukovic N, Healy N, Sparks JR, Badding JV, Horak P, Peacock AC.

Sci Rep. 2016 Mar 17;6:22825. doi: 10.1038/srep22825. No abstract available.


Pretransplantation Supportive and Palliative Care Consultation for High-Risk Hematopoietic Cell Transplantation Patients.

Loggers ET, LeBlanc TW, El-Jawahri A, Fihn J, Bumpus M, David J, Horak P, Lee SJ.

Biol Blood Marrow Transplant. 2016 Jul;22(7):1299-1305. doi: 10.1016/j.bbmt.2016.03.006. Epub 2016 Mar 11.


A nanoporous gold membrane for sensing applications.

Oo SZ, Silva G, Carpignano F, Noual A, Pechstedt K, Mateos L, Grant-Jacob JA, Brocklesby B, Horak P, Charlton M, Boden SA, Melvin T.

Sens Biosensing Res. 2016 Mar;7:133-140.


Trichobilharzia regenti (Schistosomatidae): 3D imaging techniques in characterization of larval migration through the CNS of vertebrates.

Bulantová J, Macháček T, Panská L, Krejčí F, Karch J, Jährling N, Saghafi S, Dodt HU, Horák P.

Micron. 2016 Apr;83:62-71. doi: 10.1016/j.micron.2016.01.009. Epub 2016 Feb 3.


Phase matched parametric amplification via four-wave mixing in optical microfibers.

Abdul Khudus MI, De Lucia F, Corbari C, Lee T, Horak P, Sazio P, Brambilla G.

Opt Lett. 2016 Feb 15;41(4):761-4. doi: 10.1364/OL.41.000761.


Emergency situations in rheumatology with a focus on systemic autoimmune diseases.

Vymetal J, Skacelova M, Smrzova A, Klicova A, Schubertova M, Horak P, Zadrazil J.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016 Mar;160(1):20-9. doi: 10.5507/bp.2016.002. Epub 2016 Feb 10. Review.


Comparative Transcriptomic Exploration Reveals Unique Molecular Adaptations of Neuropathogenic Trichobilharzia to Invade and Parasitize Its Avian Definitive Host.

Leontovyč R, Young ND, Korhonen PK, Hall RS, Tan P, Mikeš L, Kašný M, Horák P, Gasser RB.

PLoS Negl Trop Dis. 2016 Feb 10;10(2):e0004406. doi: 10.1371/journal.pntd.0004406. eCollection 2016 Feb.

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