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Items: 35


Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation.

Willecke F, Rupprecht B, Gissler MC, Pfeiffer K, Anto-Michel N, Stachon P, Wolf D, Hilgendorf I, Hoppe N, Bode C, Zirlik A.

J Vasc Res. 2019 Aug 22:1-12. doi: 10.1159/000501615. [Epub ahead of print]


Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome.

Merz J, Albrecht P, von Garlen S, Ahmed I, Dimanski D, Wolf D, Hilgendorf I, Härdtner C, Grotius K, Willecke F, Heidt T, Bugger H, Hoppe N, Kintscher U, von Zur Mühlen C, Idzko M, Bode C, Zirlik A, Stachon P.

Basic Res Cardiol. 2018 Oct 18;113(6):45. doi: 10.1007/s00395-018-0702-1.


The anti-inflammatory effect of exogenous lactoferrin on breeding-induced endometritis when administered post-breeding in susceptible mares.

Fedorka CE, Scoggin KE, Boakari YL, Hoppe NE, Squires EL, Ball BA, Troedsson MHT.

Theriogenology. 2018 Jul 1;114:63-69. doi: 10.1016/j.theriogenology.2018.03.017. Epub 2018 Mar 22.


Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.

Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh HQ, Kobiyama K, Hamers AAJ, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod AB, Ghosh AK, Anto Michel N, Hoppe N, Hilgendorf I, Zirlik A, Hedrick CC, Ley K, Wolf D.

Circ Res. 2018 Jun 8;122(12):1675-1688. doi: 10.1161/CIRCRESAHA.117.312513. Epub 2018 Mar 15.


Inflammatory Pathways Regulated by Tumor Necrosis Receptor-Associated Factor 1 Protect From Metabolic Consequences in Diet-Induced Obesity.

Anto Michel N, Colberg C, Buscher K, Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K, Marchini T, Willecke F, Stachon P, Hilgendorf I, Heidt T, von Zur Muhlen C, von Elverfeldt D, Pfeifer D, Schüle R, Kintscher U, Brachs S, Ley K, Bode C, Zirlik A, Wolf D.

Circ Res. 2018 Mar 2;122(5):693-700. doi: 10.1161/CIRCRESAHA.117.312055. Epub 2018 Jan 22.


Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans.

Koentges C, Pepin ME, Müsse C, Pfeil K, Alvarez SVV, Hoppe N, Hoffmann MM, Odening KE, Sossalla S, Zirlik A, Hein L, Bode C, Wende AR, Bugger H.

Basic Res Cardiol. 2017 Dec 29;113(1):8. doi: 10.1007/s00395-017-0666-6. Print 2018 Jan 8.


Gene editing & stem cells.

Harrison PT, Hoppe N, Martin U.

J Cyst Fibros. 2018 Jan;17(1):10-16. doi: 10.1016/j.jcf.2017.11.018. Epub 2017 Dec 9. Review. No abstract available.


Silicon Integrated Dual-Mode Interferometer with Differential Outputs.

Hoppe N, Scheck P, Sweidan R, Diersing P, Rathgeber L, Vogel W, Riegger B, Southan A, Berroth M.

Biosensors (Basel). 2017 Sep 14;7(3). pii: E37. doi: 10.3390/bios7030037.


P2X7 Deficiency Blocks Lesional Inflammasome Activity and Ameliorates Atherosclerosis in Mice.

Stachon P, Heidenreich A, Merz J, Hilgendorf I, Wolf D, Willecke F, von Garlen S, Albrecht P, Härdtner C, Ehrat N, Hoppe N, Reinöhl J, von Zur Mühlen C, Bode C, Idzko M, Zirlik A.

Circulation. 2017 Jun 20;135(25):2524-2533. doi: 10.1161/CIRCULATIONAHA.117.027400. Epub 2017 Apr 4.


Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).

Wolf D, Bukosza N, Engel D, Poggi M, Jehle F, Anto Michel N, Chen YC, Colberg C, Hoppe N, Dufner B, Boon L, Blankenbach H, Hilgendorf I, von Zur Muhlen C, Reinöhl J, Sommer B, Marchini T, Febbraio MA, Weber C, Bode C, Peter K, Lutgens E, Zirlik A.

Thromb Haemost. 2017 Jan 26;117(2):325-338. doi: 10.1160/TH16-07-0553. Epub 2016 Nov 17.


Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice.

Stachon P, Geis S, Peikert A, Heidenreich A, Michel NA, Ünal F, Hoppe N, Dufner B, Schulte L, Marchini T, Cicko S, Ayata K, Zech A, Wolf D, Hilgendorf I, Willecke F, Reinöhl J, von Zur Mühlen C, Bode C, Idzko M, Zirlik A.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1577-86. doi: 10.1161/ATVBAHA.115.307397. Epub 2016 Jun 23.


Privacy Laws and Biobanking in Germany.

Hoppe N.

J Law Med Ethics. 2016 Mar;44(1):35-44. doi: 10.1177/1073110516644188.


Acute exposure to air pollution particulate matter aggravates experimental myocardial infarction in mice by potentiating cytokine secretion from lung macrophages.

Marchini T, Wolf D, Michel NA, Mauler M, Dufner B, Hoppe N, Beckert J, Jäckel M, Magnani N, Duerschmied D, Tasat D, Alvarez S, Reinöhl J, von Zur Muhlen C, Idzko M, Bode C, Hilgendorf I, Evelson P, Zirlik A.

Basic Res Cardiol. 2016 Jul;111(4):44. doi: 10.1007/s00395-016-0562-5. Epub 2016 May 30.


Consent for Biobanking: The Legal Frameworks of Countries in the BioSHaRE-EU Project.

Kaye J, Briceño Moraia L, Curren L, Bell J, Mitchell C, Soini S, Hoppe N, Øien M, Rial-Sebbag E.

Biopreserv Biobank. 2016 Jun;14(3):195-200. doi: 10.1089/bio.2015.0123. Epub 2016 May 4.


Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.

Lindau A, Härdtner C, Hergeth SP, Blanz KD, Dufner B, Hoppe N, Anto-Michel N, Kornemann J, Zou J, Gerhardt LM, Heidt T, Willecke F, Geis S, Stachon P, Wolf D, Libby P, Swirski FK, Robbins CS, McPheat W, Hawley S, Braddock M, Gilsbach R, Hein L, von zur Mühlen C, Bode C, Zirlik A, Hilgendorf I.

Basic Res Cardiol. 2016 Mar;111(2):20. doi: 10.1007/s00395-016-0535-8. Epub 2016 Feb 18.


Direct-to-consumer genetic testing for predicting sports performance and talent identification: Consensus statement.

Webborn N, Williams A, McNamee M, Bouchard C, Pitsiladis Y, Ahmetov I, Ashley E, Byrne N, Camporesi S, Collins M, Dijkstra P, Eynon N, Fuku N, Garton FC, Hoppe N, Holm S, Kaye J, Klissouras V, Lucia A, Maase K, Moran C, North KN, Pigozzi F, Wang G.

Br J Sports Med. 2015 Dec;49(23):1486-91. doi: 10.1136/bjsports-2015-095343.


Effects of temperature and photoperiod on the development of overwintering immature Culicoides chiopterus and C. dewulfi.

Lühken R, Steinke S, Hoppe N, Kiel E.

Vet Parasitol. 2015 Nov 30;214(1-2):195-9. doi: 10.1016/j.vetpar.2015.10.001. Epub 2015 Oct 9.


Don't Forget the Orphans.

Grewal J, Hoppe N.

Eur J Health Law. 2015 Apr;22(2):107-11. No abstract available.


P2Y6 deficiency limits vascular inflammation and atherosclerosis in mice.

Stachon P, Peikert A, Michel NA, Hergeth S, Marchini T, Wolf D, Dufner B, Hoppe N, Ayata CK, Grimm M, Cicko S, Schulte L, Reinöhl J, von zur Muhlen C, Bode C, Idzko M, Zirlik A.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2237-45. doi: 10.1161/ATVBAHA.114.303585. Epub 2014 Aug 7.


Outcome stagnation of liver transplantation for primary sclerosing cholangitis in the Model for End-Stage Liver Disease era.

Klose J, Klose MA, Metz C, Lehner F, Manns MP, Klempnauer J, Hoppe N, Schrem H, Kaltenborn A.

Langenbecks Arch Surg. 2014 Dec;399(8):1021-9. doi: 10.1007/s00423-014-1214-6. Epub 2014 Jun 4.


Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice.

Wolf D, Jehle F, Michel NA, Bukosza EN, Rivera J, Chen YC, Hoppe N, Dufner B, Rodriguez AO, Colberg C, Nieto L, Rupprecht B, Wiedemann A, Schulte L, Peikert A, Bassler N, Lozhkin A, Hergeth SP, Stachon P, Hilgendorf I, Willecke F, von Zur Mühlen C, von Elverfeldt D, Binder CJ, Aichele P, Varo N, Febbraio MA, Libby P, Bode C, Peter K, Zirlik A.

Circulation. 2014 Jun 10;129(23):2414-25. doi: 10.1161/CIRCULATIONAHA.113.008055. Epub 2014 Mar 24.


Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice.

Willecke F, Tiwari S, Rupprecht B, Wolf D, Hergeth S, Hoppe N, Dufner B, Schulte L, Anto Michel N, Bukosza N, Marchini T, Jäckel M, Stachon P, Hilgendorf I, Zeschky K, Schleicher R, Langer HF, von Zur Muhlen C, Bode C, Peter K, Zirlik A.

Thromb Haemost. 2014 Aug;112(2):379-89. doi: 10.1160/TH13-08-0653. Epub 2014 Mar 20.


From omics and etics to policy and ethics: regulating evolution.

Hoppe N.

Front Genet. 2013 Sep 19;4:172. doi: 10.3389/fgene.2013.00172. eCollection 2013. No abstract available.


Organ transplantation in Germany: regulating scandals and scandalous regulation.

Metz C, Hoppe N.

Eur J Health Law. 2013 Apr;20(2):113-6. No abstract available.


[Current medicolegal and ethical issues in pathology].

Robienski J, Hoppe N.

Pathologe. 2013 Feb;34(1):9-15. doi: 10.1007/s00292-012-1703-8. Review. German.


Research priorities. ELSI 2.0 for genomics and society.

Kaye J, Meslin EM, Knoppers BM, Juengst ET, Deschênes M, Cambon-Thomsen A, Chalmers D, De Vries J, Edwards K, Hoppe N, Kent A, Adebamowo C, Marshall P, Kato K.

Science. 2012 May 11;336(6082):673-4. doi: 10.1126/science.1218015. No abstract available.


CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies.

Wolf D, Jehle F, Ortiz Rodriguez A, Dufner B, Hoppe N, Colberg C, Lozhkin A, Bassler N, Rupprecht B, Wiedemann A, Hilgendorf I, Stachon P, Willecke F, Febbraio M, von zur Muhlen C, Binder CJ, Bode C, Zirlik A, Peter K.

PLoS One. 2012;7(3):e33026. doi: 10.1371/journal.pone.0033026. Epub 2012 Mar 8. Erratum in: PLoS One. 2012;7(5): doi/10.1371/annotation/84102aae-770a-41ae-9c15-4736ed129c17. von zur Muhlen, Constantin [added]..


Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.

Wolf D, Hohmann JD, Wiedemann A, Bledzka K, Blankenbach H, Marchini T, Gutte K, Zeschky K, Bassler N, Hoppe N, Rodriguez AO, Herr N, Hilgendorf I, Stachon P, Willecke F, Duerschmied D, von zur Muhlen C, Soloviev DA, Zhang L, Bode C, Plow EF, Libby P, Peter K, Zirlik A.

Circ Res. 2011 Nov 11;109(11):1269-79. doi: 10.1161/CIRCRESAHA.111.247684. Epub 2011 Oct 13.


The oral spleen tyrosine kinase inhibitor fostamatinib attenuates inflammation and atherogenesis in low-density lipoprotein receptor-deficient mice.

Hilgendorf I, Eisele S, Remer I, Schmitz J, Zeschky K, Colberg C, Stachon P, Wolf D, Willecke F, Buchner M, Zirlik K, Ortiz-Rodriguez A, Lozhkin A, Hoppe N, von zur Muhlen C, zur Hausen A, Bode C, Zirlik A.

Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):1991-9. doi: 10.1161/ATVBAHA.111.230847. Epub 2011 Jun 23.


An ethical framework for expanded access to cell-based therapies.

Hoppe N, Denoon A.

Regen Med. 2011 May;6(3):273-5. doi: 10.2217/rme.11.12. No abstract available.


Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice.

Willecke F, Zeschky K, Ortiz Rodriguez A, Colberg C, Auwärter V, Kneisel S, Hutter M, Lozhkin A, Hoppe N, Wolf D, von zur Mühlen C, Moser M, Hilgendorf I, Bode C, Zirlik A.

PLoS One. 2011 Apr 26;6(4):e19405. doi: 10.1371/journal.pone.0019405.


On the Europeanization of health law.

Hoppe N.

Eur J Health Law. 2010 Sep;17(4):323-8. No abstract available.


TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.

Missiou A, Rudolf P, Stachon P, Wolf D, Varo N, Aichele P, Colberg C, Hoppe N, Ernst S, Münkel C, Walter C, Sommer B, Hilgendorf I, Nakano H, Bode C, Zirlik A.

Circ Res. 2010 Sep 17;107(6):757-66. doi: 10.1161/CIRCRESAHA.110.219295. Epub 2010 Jul 22.


Optimization of buffer rod geometry for ultrasonic sensors with reference path.

Hoppe N, Püttmer A, Hauptmann P.

IEEE Trans Ultrason Ferroelectr Freq Control. 2003 Feb;50(2):170-8.


Some improvements in the synthesis of DNA of biological interest.

Köster H, Hoppe N, Kohli V, Kröpelin M, Kaut H, Kulikowski K.

Nucleic Acids Symp Ser. 1980;(7):39-60.


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