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Items: 38

1.

PARP1 trapping by PARP inhibitors drives cytotoxicity both in cancer cells and healthy bone marrow.

Hopkins TA, Ainsworth WB, Ellis PA, Donawho CK, DiGiammarino EL, Panchal SC, Abraham VC, Algire MA, Shi Y, Olson AM, Johnson EF, Wilsbacher JL, Maag D.

Mol Cancer Res. 2018 Nov 14. pii: molcanres.0138.2018. doi: 10.1158/1541-7786.MCR-18-0138. [Epub ahead of print]

PMID:
30429212
2.

Deep Eutectic Solvents for Induced Circularly Polarized Luminescence.

Wright CR, VandenElzen L, Hopkins TA.

J Phys Chem B. 2018 Sep 20;122(37):8730-8737. doi: 10.1021/acs.jpcb.8b06148. Epub 2018 Sep 5.

PMID:
30145897
3.

Barriers to the use of Veterans Affairs health care services among female veterans who served in Iraq and Afghanistan.

Newins AR, Wilson SM, Hopkins TA, Straits-Troster K, Kudler H, Calhoun PS.

Psychol Serv. 2018 Feb 8. doi: 10.1037/ser0000230. [Epub ahead of print]

PMID:
29419309
4.

In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir.

Ng TI, Tripathi R, Reisch T, Lu L, Middleton T, Hopkins TA, Pithawalla R, Irvin M, Dekhtyar T, Krishnan P, Schnell G, Beyer J, McDaniel KF, Ma J, Wang G, Jiang LJ, Or YS, Kempf D, Pilot-Matias T, Collins C.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01620-17. doi: 10.1128/AAC.01620-17. Print 2018 Jan.

5.

Erratum: "Erratum: Study of SF6 adsorption on graphite using infrared spectroscopy" [J. Chem. Phys. 145, 249901 (2016)].

Thomas P, Xia Y, Boyd DA, Hopkins TA, Hess GB.

J Chem Phys. 2017 Jun 28;146(24):249901. doi: 10.1063/1.4990047. No abstract available.

PMID:
28668058
6.

Erratum: "Study of SF6 adsorption on graphite using infrared spectroscopy" [J. Chem. Phys. 131, 124709 (2009)].

Thomas P, Xia Y, Boyd DA, Hopkins TA, Hess GB.

J Chem Phys. 2016 Dec 28;145(24):249901. doi: 10.1063/1.4973240. No abstract available.

PMID:
28049329
7.

Induction of Circularly Polarized Luminescence from Europium by Amino Acid Based Ionic Liquids.

Zercher B, Hopkins TA.

Inorg Chem. 2016 Nov 7;55(21):10899-10906. Epub 2016 Oct 24.

PMID:
27775336
8.

Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors.

Hopkins TA, Shi Y, Rodriguez LE, Solomon LR, Donawho CK, DiGiammarino EL, Panchal SC, Wilsbacher JL, Gao W, Olson AM, Stolarik DF, Osterling DJ, Johnson EF, Maag D.

Mol Cancer Res. 2015 Nov;13(11):1465-77. doi: 10.1158/1541-7786.MCR-15-0191-T. Epub 2015 Jul 27.

9.

Chiral discrimination by ionic liquids: impact of ionic solutes.

Brown CJ, Hopkins TA.

Chirality. 2015 Apr;27(4):320-5. doi: 10.1002/chir.22435. Epub 2015 Feb 26.

PMID:
25727925
10.

Clinical relevance of the proposed sexual addiction diagnostic criteria: relation to the Sexual Addiction Screening Test-Revised.

Carnes PJ, Hopkins TA, Green BA.

J Addict Med. 2014 Nov-Dec;8(6):450-61. doi: 10.1097/ADM.0000000000000080.

PMID:
25303984
11.

Equine-related treatments for mental disorders lack empirical support: a systematic review of empirical investigations.

Anestis MD, Anestis JC, Zawilinski LL, Hopkins TA, Lilienfeld SO.

J Clin Psychol. 2014 Dec;70(12):1115-32. doi: 10.1002/jclp.22113. Epub 2014 Jun 20. Review.

PMID:
24953870
12.

Chiroptical study of chiral discrimination by amino acid based ionic liquids.

Kroupa DM, Brown CJ, Heckman LM, Hopkins TA.

J Phys Chem B. 2012 Apr 26;116(16):4952-8. doi: 10.1021/jp300357z. Epub 2012 Apr 11.

PMID:
22462559
13.

Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility.

Nieman JA, Nair SK, Heasley SE, Schultz BL, Zerth HM, Nugent RA, Chen K, Stephanski KJ, Hopkins TA, Knechtel ML, Oien NL, Wieber JL, Wathen MW.

Bioorg Med Chem Lett. 2010 May 15;20(10):3039-42. doi: 10.1016/j.bmcl.2010.03.115. Epub 2010 Apr 3.

PMID:
20403696
14.

The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase.

Tanis SP, Strohbach JW, Parker TT, Moon MW, Thaisrivongs S, Perrault WR, Hopkins TA, Knechtel ML, Oien NL, Wieber JL, Stephanski KJ, Wathen MW.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1994-2000. doi: 10.1016/j.bmcl.2010.01.094. Epub 2010 Jan 25.

PMID:
20167488
15.

Study of SF6 adsorption on graphite using infrared spectroscopy.

Thomas P, Xia Y, Boyd DA, Hopkins TA, Hess GB.

J Chem Phys. 2009 Sep 28;131(12):124709. doi: 10.1063/1.3226561.

PMID:
19791914
16.

Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition.

Schnute ME, Brideau RJ, Collier SA, Cudahy MM, Hopkins TA, Knechtel ML, Oien NL, Sackett RS, Scott A, Stephan ML, Wathen MW, Wieber JL.

Bioorg Med Chem Lett. 2008 Jul 15;18(14):3856-9. doi: 10.1016/j.bmcl.2008.06.060. Epub 2008 Jun 20.

PMID:
18595689
17.

Infrared spectroscopic study of C(2)F(6) monolayers and bilayers on graphite.

Hopkins TA, Boyd DA, Xia Y, Shifflett GM, Hess FM, Hess GB.

J Chem Phys. 2008 Apr 21;128(15):154714. doi: 10.1063/1.2903479.

PMID:
18433265
18.

Angiotensin-converting enzyme inhibition after experimental myocardial infarct: role of the kinin B1 and B2 receptors.

Duka A, Kintsurashvili E, Duka I, Ona D, Hopkins TA, Bader M, Gavras I, Gavras H.

Hypertension. 2008 May;51(5):1352-7. doi: 10.1161/HYPERTENSIONAHA.107.108506. Epub 2008 Mar 17.

PMID:
18347228
19.

Intermolecular chiral recognition processes probed by chiroptical luminescence.

Hopkins TA, Metcalf DH, Richardson FS.

Chirality. 2008 Mar;20(3-4):511-23.

PMID:
17963202
20.

7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.

Larsen SD, Zhang Z, DiPaolo BA, Manninen PR, Rohrer DC, Hageman MJ, Hopkins TA, Knechtel ML, Oien NL, Rush BD, Schwende FJ, Stefanski KJ, Wieber JL, Wilkinson KF, Zamora KM, Wathen MW, Brideau RJ.

Bioorg Med Chem Lett. 2007 Jul 15;17(14):3840-4. Epub 2007 May 10.

PMID:
17513108
21.

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.

Schnute ME, Anderson DJ, Brideau RJ, Ciske FL, Collier SA, Cudahy MM, Eggen M, Genin MJ, Hopkins TA, Judge TM, Kim EJ, Knechtel ML, Nair SK, Nieman JA, Oien NL, Scott A, Tanis SP, Vaillancourt VA, Wathen MW, Wieber JL.

Bioorg Med Chem Lett. 2007 Jun 15;17(12):3349-53. Epub 2007 Apr 5.

PMID:
17434304
22.

Adiponectin actions in the cardiovascular system.

Hopkins TA, Ouchi N, Shibata R, Walsh K.

Cardiovasc Res. 2007 Apr 1;74(1):11-8. Epub 2006 Oct 20. Review.

23.

Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury.

Dyck JR, Hopkins TA, Bonnet S, Michelakis ED, Young ME, Watanabe M, Kawase Y, Jishage K, Lopaschuk GD.

Circulation. 2006 Oct 17;114(16):1721-8. Epub 2006 Oct 9.

PMID:
17030679
24.

4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.

Schnute ME, Cudahy MM, Brideau RJ, Homa FL, Hopkins TA, Knechtel ML, Oien NL, Pitts TW, Poorman RA, Wathen MW, Wieber JL.

J Med Chem. 2005 Sep 8;48(18):5794-804.

PMID:
16134946
25.

Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice.

Hopkins TA, Sugden MC, Holness MJ, Kozak R, Dyck JR, Lopaschuk GD.

Am J Physiol Heart Circ Physiol. 2003 Jul;285(1):H270-6. Epub 2003 Mar 27.

26.

AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart.

Hopkins TA, Dyck JR, Lopaschuk GD.

Biochem Soc Trans. 2003 Feb;31(Pt 1):207-12. Review.

PMID:
12546686
28.

Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart.

Onay-Besikci A, Campbell FM, Hopkins TA, Dyck JR, Lopaschuk GD.

Am J Physiol Heart Circ Physiol. 2003 Jan;284(1):H283-9. Epub 2002 Sep 5. Erratum in: Am J Physiol Heart Circ Physiol. 2003 Sep;285(3):H1362. Onay Besikci Arzu [corrected to Onay-Besikci Arzu].

29.

Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses.

Brideau RJ, Knechtel ML, Huang A, Vaillancourt VA, Vera EE, Oien NL, Hopkins TA, Wieber JL, Wilkinson KF, Rush BD, Schwende FJ, Wathen MW.

Antiviral Res. 2002 Apr;54(1):19-28.

PMID:
11888654
30.

Broad-spectrum antiherpes activities of 4-hydroxyquinoline carboxamides, a novel class of herpesvirus polymerase inhibitors.

Oien NL, Brideau RJ, Hopkins TA, Wieber JL, Knechtel ML, Shelly JA, Anstadt RA, Wells PA, Poorman RA, Huang A, Vaillancourt VA, Clayton TL, Tucker JA, Wathen MW.

Antimicrob Agents Chemother. 2002 Mar;46(3):724-30.

31.

Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.

Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Moudgil R, Hopkins TA, Lopaschuk GD, Puttagunta L, Waite R, Archer SL.

Circulation. 2002 Jan 15;105(2):244-50.

PMID:
11790708
32.
33.

Spectroscopy of UO(2)Cl(4)(2)(-) in basic aluminum chloride-1-ethyl-3-methylimidazolium chloride.

Hopkins TA, Berg JM, Costa DA, Smith WH, Dewey HJ.

Inorg Chem. 2001 Apr 9;40(8):1820-5.

PMID:
11312737
34.

Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism.

Dyck JR, Berthiaume LG, Thomas PD, Kantor PF, Barr AJ, Barr R, Singh D, Hopkins TA, Voilley N, Prentki M, Lopaschuk GD.

Biochem J. 2000 Sep 1;350 Pt 2:599-608.

35.

Peroxisomes of the firefly lantern.

Hanna CH, Hopkins TA, Buck J.

J Ultrastruct Res. 1976 Nov;57(2):150-62. No abstract available.

PMID:
994283
36.

Chemi- and bioluminescence of firefly luciferin.

White EH, Rapaport E, Hopkins TA, Seliger HH.

J Am Chem Soc. 1969 Apr 9;91(8):2178-80. No abstract available.

PMID:
5784183
37.

The spectroscopic properties of firefly luciferin and related compounds. An approach to product emission.

Morton RA, Hopkins TA, Seliger HH.

Biochemistry. 1969 Apr;8(4):1598-607. No abstract available.

PMID:
5805299
38.

The chemiluminescence of firefly luciferin. A model for the bioluminescent reaction and identification of the product excited state.

Hopkins TA, Seliger HH, White EH, Cass MH.

J Am Chem Soc. 1967 Dec 20;89(26):7148-50. No abstract available.

PMID:
6064360

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