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Items: 1 to 50 of 145

1.

A multi-species cluster of GES-5 carbapenemase producing Enterobacterales linked by a geographically disseminated plasmid.

Ellington MJ, Davies F, Jauneikaite E, Hopkins KL, Turton JF, Adams G, Pavlu J, Innes AJ, Eades C, Brannigan ET, Findlay J, White L, Bolt F, Kadhani T, Chow Y, Patel B, Mookerjee S, Otter JA, Sriskandan S, Woodford N, Holmes A.

Clin Infect Dis. 2019 Nov 20. pii: ciz1130. doi: 10.1093/cid/ciz1130. [Epub ahead of print]

PMID:
31746994
2.

Evaluation of temocillin and meropenem MICs as diagnostic markers for OXA-48-like carbapenemases.

Hopkins KL, Meunier D, Mustafa N, Pike R, Woodford N.

J Antimicrob Chemother. 2019 Dec 1;74(12):3641-3643. doi: 10.1093/jac/dkz383. No abstract available.

PMID:
31730158
3.

Extended-spectrum β-lactamase-producing Escherichia coli in human-derived and foodchain-derived samples from England, Wales, and Scotland: an epidemiological surveillance and typing study.

Day MJ, Hopkins KL, Wareham DW, Toleman MA, Elviss N, Randall L, Teale C, Cleary P, Wiuff C, Doumith M, Ellington MJ, Woodford N, Livermore DM.

Lancet Infect Dis. 2019 Dec;19(12):1325-1335. doi: 10.1016/S1473-3099(19)30273-7. Epub 2019 Oct 22.

4.

Emergence of diversity in carbapenemase-producing Escherichia coli ST131, England, January 2014 to June 2016.

Ellaby N, Doumith M, Hopkins KL, Woodford N, Ellington MJ.

Euro Surveill. 2019 Sep;24(37). doi: 10.2807/1560-7917.ES.2019.24.37.1800627.

5.

Molecular characterization of carbapenem-resistant Escherichia coli and Acinetobacter baumannii in the Lao People's Democratic Republic.

Cusack TP, Phimolsarnnousith V, Duangmala K, Phoumin P, Turton J, Hopkins KL, Woodford N, Shetty N, Stoesser N, Phan HTT, Dance DAB.

J Antimicrob Chemother. 2019 Sep 1;74(9):2810-2821. doi: 10.1093/jac/dkz234. No abstract available.

6.

An evaluation of the electronic reporting system for the enhanced surveillance of carbapenemase-producing Gram-negative bacteria in England.

Jermacane D, Coope CM, Ironmonger D, Cleary P, Muller-Pebody B, Hope R, Hopkins S, Puleston R, Freeman R, Hopkins KL, Johnson AP, Woodford N, Oliver I.

J Hosp Infect. 2019 May;102(1):17-24. doi: 10.1016/j.jhin.2019.01.005. Epub 2019 Jan 12.

PMID:
30641097
7.

A case of NDM-carbapenemase-producing hypervirulent Klebsiella pneumoniae sequence type 23 from the UK.

Roulston KJ, Bharucha T, Turton JF, Hopkins KL, Mack DJF.

JMM Case Rep. 2018 May 17;5(9):e005130. doi: 10.1099/jmmcr.0.005130. eCollection 2018 Sep.

8.

OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli.

Livermore DM, Day M, Cleary P, Hopkins KL, Toleman MA, Wareham DW, Wiuff C, Doumith M, Woodford N.

J Antimicrob Chemother. 2019 Feb 1;74(2):326-333. doi: 10.1093/jac/dky453.

PMID:
30388219
9.

Will the current National Strategic Plan enable South Africa to end AIDS, Tuberculosis and Sexually Transmitted Infections by 2022?

Hopkins KL, Doherty T, Gray GE.

South Afr J HIV Med. 2018 Oct 4;19(1):796. doi: 10.4102/sajhivmed.v19i1.796. eCollection 2018.

10.
11.
12.

Evaluation of the NG-Test CARBA 5 multiplex immunochromatographic assay for the detection of KPC, OXA-48-like, NDM, VIM and IMP carbapenemases.

Hopkins KL, Meunier D, Naas T, Volland H, Woodford N.

J Antimicrob Chemother. 2018 Dec 1;73(12):3523-3526. doi: 10.1093/jac/dky342. No abstract available.

PMID:
30189008
13.

Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones.

Roer L, Overballe-Petersen S, Hansen F, Schønning K, Wang M, Røder BL, Hansen DS, Justesen US, Andersen LP, Fulgsang-Damgaard D, Hopkins KL, Woodford N, Falgenhauer L, Chakraborty T, Samuelsen Ø, Sjöström K, Johannesen TB, Ng K, Nielsen J, Ethelberg S, Stegger M, Hammerum AM, Hasman H.

mSphere. 2018 Jul 18;3(4). pii: e00337-18. doi: 10.1128/mSphere.00337-18.

14.

Author Correction: Rapid susceptibility profiling of carbapenem-resistant Klebsiella pneumoniae.

Mulroney KT, Hall JM, Huang X, Turnbull E, Bzdyl NM, Chakera A, Naseer U, Corea EM, Ellington MJ, Hopkins KL, Wester AL, Ekelund O, Woodford N, Inglis TJJ.

Sci Rep. 2018 Apr 24;8(1):6697. doi: 10.1038/s41598-018-25216-y.

15.

Characterization of Carbapenemase-Producing Enterobacteriaceae from Patients in Amman, Jordan.

Aqel AA, Findlay J, Al-Maayteh M, Al-Kaabneh A, Hopkins KL, Alzoubi H, Masalha I, Turton J, Woodford N, Ellington MJ.

Microb Drug Resist. 2018 Oct;24(8):1121-1127. doi: 10.1089/mdr.2017.0238. Epub 2018 Mar 8.

PMID:
29653473
16.

Prediction of Phenotypic Antimicrobial Resistance Profiles From Whole Genome Sequences of Non-typhoidal Salmonella enterica.

Neuert S, Nair S, Day MR, Doumith M, Ashton PM, Mellor KC, Jenkins C, Hopkins KL, Woodford N, de Pinna E, Godbole G, Dallman TJ.

Front Microbiol. 2018 Mar 27;9:592. doi: 10.3389/fmicb.2018.00592. eCollection 2018.

17.

High prevalence of 16S rRNA methyltransferases among carbapenemase-producing Enterobacteriaceae in the UK and Ireland.

Taylor E, Sriskandan S, Woodford N, Hopkins KL.

Int J Antimicrob Agents. 2018 Aug;52(2):278-282. doi: 10.1016/j.ijantimicag.2018.03.016. Epub 2018 Mar 27.

18.

Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection.

Fraser-Pitt DJ, Mercer DK, Smith D, Kowalczuk A, Robertson J, Lovie E, Perenyi P, Cole M, Doumith M, Hill RLR, Hopkins KL, Woodford N, O'Neil DA.

Infect Immun. 2018 May 22;86(6). pii: e00947-17. doi: 10.1128/IAI.00947-17. Print 2018 Jun.

19.

Pseudomonas aeruginosa sequence type 357 with VEB extended-spectrum β-lactamases in the UK: relatedness and resistance.

Greenwood B, Meunier D, Hopkins KL, Pike R, Ivanov Z, Turton JF, Hill R, Woodford N, Livermore DM.

Int J Antimicrob Agents. 2018 Aug;52(2):301-302. doi: 10.1016/j.ijantimicag.2018.03.013. Epub 2018 Mar 23. No abstract available.

PMID:
29580931
20.

Activity of ceftazidime/avibactam against problem Enterobacteriaceae and Pseudomonas aeruginosa in the UK, 2015-16.

Livermore DM, Meunier D, Hopkins KL, Doumith M, Hill R, Pike R, Staves P, Woodford N.

J Antimicrob Chemother. 2018 Mar 1;73(3):648-657. doi: 10.1093/jac/dkx438.

PMID:
29228202
21.

Comparison of phenotypic and WGS-derived antimicrobial resistance profiles of Salmonella enterica serovars Typhi and Paratyphi.

Day MR, Doumith M, Do Nascimento V, Nair S, Ashton PM, Jenkins C, Dallman TJ, Stevens FJ, Freedman J, Hopkins KL, Woodford N, De Pinna EM, Godbole G.

J Antimicrob Chemother. 2018 Feb 1;73(2):365-372. doi: 10.1093/jac/dkx379.

PMID:
29216342
22.

Virulence genes in isolates of Klebsiella pneumoniae from the UK during 2016, including among carbapenemase gene-positive hypervirulent K1-ST23 and 'non-hypervirulent' types ST147, ST15 and ST383.

Turton JF, Payne Z, Coward A, Hopkins KL, Turton JA, Doumith M, Woodford N.

J Med Microbiol. 2018 Jan;67(1):118-128. doi: 10.1099/jmm.0.000653. Epub 2017 Dec 5.

PMID:
29205138
23.

Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014.

Samuelsen Ø, Overballe-Petersen S, Bjørnholt JV, Brisse S, Doumith M, Woodford N, Hopkins KL, Aasnæs B, Haldorsen B, Sundsfjord A; Norwegian Study Group on CPE.

PLoS One. 2017 Nov 15;12(11):e0187832. doi: 10.1371/journal.pone.0187832. eCollection 2017.

24.

Sharing of carbapenemase-encoding plasmids between Enterobacteriaceae in UK sewage uncovered by MinION sequencing.

Ludden C, Reuter S, Judge K, Gouliouris T, Blane B, Coll F, Naydenova P, Hunt M, Tracey A, Hopkins KL, Brown NM, Woodford N, Parkhill J, Peacock SJ.

Microb Genom. 2017 Jul 4;3(7):e000114. doi: 10.1099/mgen.0.000114. eCollection 2017 Jul.

25.

Emergence and clonal spread of colistin resistance due to multiple mutational mechanisms in carbapenemase-producing Klebsiella pneumoniae in London.

Otter JA, Doumith M, Davies F, Mookerjee S, Dyakova E, Gilchrist M, Brannigan ET, Bamford K, Galletly T, Donaldson H, Aanensen DM, Ellington MJ, Hill R, Turton JF, Hopkins KL, Woodford N, Holmes A.

Sci Rep. 2017 Oct 5;7(1):12711. doi: 10.1038/s41598-017-12637-4.

26.

Comparison of phenotypic and WGS-derived antimicrobial resistance profiles of enteroaggregative Escherichia coli isolated from cases of diarrhoeal disease in England, 2015-16.

Do Nascimento V, Day MR, Doumith M, Hopkins KL, Woodford N, Godbole G, Jenkins C.

J Antimicrob Chemother. 2017 Dec 1;72(12):3288-3297. doi: 10.1093/jac/dkx301.

PMID:
28961934
27.

Covert dissemination of carbapenemase-producing Klebsiella pneumoniae (KPC) in a successfully controlled outbreak: long- and short-read whole-genome sequencing demonstrate multiple genetic modes of transmission.

Martin J, Phan HTT, Findlay J, Stoesser N, Pankhurst L, Navickaite I, De Maio N, Eyre DW, Toogood G, Orsi NM, Kirby A, Young N, Turton JF, Hill RLR, Hopkins KL, Woodford N, Peto TEA, Walker AS, Crook DW, Wilcox MH.

J Antimicrob Chemother. 2017 Nov 1;72(11):3025-3034. doi: 10.1093/jac/dkx264.

28.

Multicentre evaluation of the BYG Carba v2.0 test, a simplified electrochemical assay for the rapid laboratory detection of carbapenemase-producing Enterobacteriaceae.

Bogaerts P, Oueslati S, Meunier D, Nonhoff C, Yunus S, Massart M, Denis O, Woodford N, Hopkins KL, Naas T, Dortet L, Huang TD, Glupczynski Y.

Sci Rep. 2017 Aug 30;7(1):9937. doi: 10.1038/s41598-017-09820-y.

29.

First outbreak of colonization by linezolid- and glycopeptide-resistant Enterococcus faecium harbouring the cfr gene in a UK nephrology unit.

Inkster T, Coia J, Meunier D, Doumith M, Martin K, Pike R, Imrie L, Kane H, Hay M, Wiuff C, Wilson J, Deighan C, Hopkins KL, Woodford N, Hill R.

J Hosp Infect. 2017 Dec;97(4):397-402. doi: 10.1016/j.jhin.2017.07.003. Epub 2017 Jul 8.

PMID:
28698020
30.

Performance characteristics of magnetic resonance imaging without contrast agents or sedation in pediatric appendicitis.

Didier RA, Hopkins KL, Coakley FV, Krishnaswami S, Spiro DM, Foster BR.

Pediatr Radiol. 2017 Sep;47(10):1312-1320. doi: 10.1007/s00247-017-3897-7. Epub 2017 Jun 19.

PMID:
28631157
31.

FRI-2 carbapenemase-producing Enterobacter cloacae complex in the UK.

Meunier D, Findlay J, Doumith M, Godoy D, Perry C, Pike R, Gronthoud F, Shryane T, Poirel L, Welfare W, Woodford N, Hopkins KL.

J Antimicrob Chemother. 2017 Sep 1;72(9):2478-2482. doi: 10.1093/jac/dkx173.

PMID:
28605515
32.

Comparison of phenotypic and WGS-derived antimicrobial resistance profiles of Shigella sonnei isolated from cases of diarrhoeal disease in England and Wales, 2015.

Sadouki Z, Day MR, Doumith M, Chattaway MA, Dallman TJ, Hopkins KL, Elson R, Woodford N, Godbole G, Jenkins C.

J Antimicrob Chemother. 2017 Sep 1;72(9):2496-2502. doi: 10.1093/jac/dkx170.

PMID:
28591819
33.

Activity of ceftolozane/tazobactam against surveillance and 'problem' Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles.

Livermore DM, Mushtaq S, Meunier D, Hopkins KL, Hill R, Adkin R, Chaudhry A, Pike R, Staves P, Woodford N; BSAC Resistance Surveillance Standing Committee.

J Antimicrob Chemother. 2017 Aug 1;72(8):2278-2289. doi: 10.1093/jac/dkx136.

34.

Rapid susceptibility profiling of carbapenem-resistant Klebsiella pneumoniae.

Mulroney KT, Hall JM, Huang X, Turnbull E, Bzdyl NM, Chakera A, Naseer U, Corea EM, Ellington MJ, Hopkins KL, Wester AL, Ekelund O, Woodford N, Inglis TJJ.

Sci Rep. 2017 May 15;7(1):1903. doi: 10.1038/s41598-017-02009-3. Erratum in: Sci Rep. 2018 Apr 24;8(1):6697.

35.

Major role of pKpQIL-like plasmids in the early dissemination of KPC-type carbapenemases in the UK.

Doumith M, Findlay J, Hirani H, Hopkins KL, Livermore DM, Dodgson A, Woodford N.

J Antimicrob Chemother. 2017 Aug 1;72(8):2241-2248. doi: 10.1093/jac/dkx141.

PMID:
28498924
36.

The relative importance of large problems far away versus small problems closer to home: insights into limiting the spread of antimicrobial resistance in England.

Donker T, Henderson KL, Hopkins KL, Dodgson AR, Thomas S, Crook DW, Peto TEA, Johnson AP, Woodford N, Walker AS, Robotham JV.

BMC Med. 2017 Apr 27;15(1):86. doi: 10.1186/s12916-017-0844-2.

37.

IMI-2 carbapenemase in a clinical Klebsiella variicola isolated in the UK.

Hopkins KL, Findlay J, Doumith M, Mather B, Meunier D, D'Arcy S, Pike R, Mustafa N, Howe R, Wootton M, Woodford N.

J Antimicrob Chemother. 2017 Jul 1;72(7):2129-2131. doi: 10.1093/jac/dkx103. No abstract available.

PMID:
28379381
38.

Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings.

Feasey NA, Hadfield J, Keddy KH, Dallman TJ, Jacobs J, Deng X, Wigley P, Barquist L, Langridge GC, Feltwell T, Harris SR, Mather AE, Fookes M, Aslett M, Msefula C, Kariuki S, Maclennan CA, Onsare RS, Weill FX, Le Hello S, Smith AM, McClelland M, Desai P, Parry CM, Cheesbrough J, French N, Campos J, Chabalgoity JA, Betancor L, Hopkins KL, Nair S, Humphrey TJ, Lunguya O, Cogan TA, Tapia MD, Sow SO, Tennant SM, Bornstein K, Levine MM, Lacharme-Lora L, Everett DB, Kingsley RA, Parkhill J, Heyderman RS, Dougan G, Gordon MA, Thomson NR.

Nat Genet. 2017 Mar 30;49(4):651. doi: 10.1038/ng0417-651c. No abstract available.

PMID:
28358127
39.

OXA-48-like carbapenemases in the UK: an analysis of isolates and cases from 2007 to 2014.

Findlay J, Hopkins KL, Loy R, Doumith M, Meunier D, Hill R, Pike R, Mustafa N, Livermore DM, Woodford N.

J Antimicrob Chemother. 2017 May 1;72(5):1340-1349. doi: 10.1093/jac/dkx012.

PMID:
28199647
40.

Serratia marcescens producing SME carbapenemases: an emerging resistance problem in the UK?

Hopkins KL, Findlay J, Meunier D, Cummins M, Curtis S, Kustos I, Mustafa N, Perry C, Pike R, Woodford N.

J Antimicrob Chemother. 2017 May 1;72(5):1535-1537. doi: 10.1093/jac/dkw567. No abstract available.

PMID:
28108680
41.

Characterization of carbapenemase-producing Enterobacteriaceae in the West Midlands region of England: 2007-14.

Findlay J, Hopkins KL, Alvarez-Buylla A, Meunier D, Mustafa N, Hill R, Pike R, McCrae LX, Hawkey PM, Woodford N.

J Antimicrob Chemother. 2017 Apr 1;72(4):1054-1062. doi: 10.1093/jac/dkw560.

PMID:
28073969
42.

The role of whole genome sequencing in antimicrobial susceptibility testing of bacteria: report from the EUCAST Subcommittee.

Ellington MJ, Ekelund O, Aarestrup FM, Canton R, Doumith M, Giske C, Grundman H, Hasman H, Holden MTG, Hopkins KL, Iredell J, Kahlmeter G, Köser CU, MacGowan A, Mevius D, Mulvey M, Naas T, Peto T, Rolain JM, Samuelsen Ø, Woodford N.

Clin Microbiol Infect. 2017 Jan;23(1):2-22. doi: 10.1016/j.cmi.2016.11.012. Epub 2016 Nov 23. Review.

43.

Evaluation of meat, fruit and vegetables from retail stores in five United Kingdom regions as sources of extended-spectrum beta-lactamase (ESBL)-producing and carbapenem-resistant Escherichia coli.

Randall LP, Lodge MP, Elviss NC, Lemma FL, Hopkins KL, Teale CJ, Woodford N.

Int J Food Microbiol. 2017 Jan 16;241:283-290. doi: 10.1016/j.ijfoodmicro.2016.10.036. Epub 2016 Oct 29.

PMID:
27821357
44.

The differential importance of mutations within AmpD in cephalosporin resistance of Enterobacter aerogenes and Enterobacter cloacae.

Babouee Flury B, Ellington MJ, Hopkins KL, Turton JF, Doumith M, Woodford N.

Int J Antimicrob Agents. 2016 Nov;48(5):555-558. doi: 10.1016/j.ijantimicag.2016.07.021. Epub 2016 Sep 12.

PMID:
27665520
45.

Carbapenemase-producing Enterobacteriaceae in the UK: a national study (EuSCAPE-UK) on prevalence, incidence, laboratory detection methods and infection control measures.

Trepanier P, Mallard K, Meunier D, Pike R, Brown D, Ashby JP, Donaldson H, Awad-El-Kariem FM, Balakrishnan I, Cubbon M, Chadwick PR, Doughton M, Doughton R, Hardiman F, Harvey G, Horner C, Lee J, Lewis J, Loughrey A, Manuel R, Parsons H, Perry JD, Vanstone G, White G, Shetty N, Coia J, Wiuff C, Hopkins KL, Woodford N.

J Antimicrob Chemother. 2017 Feb;72(2):596-603. doi: 10.1093/jac/dkw414. Epub 2016 Sep 29.

PMID:
27687074
46.

Antimicrobial resistance in Shiga toxin-producing Escherichia coli serogroups O157 and O26 isolated from human cases of diarrhoeal disease in England, 2015.

Day M, Doumith M, Jenkins C, Dallman TJ, Hopkins KL, Elson R, Godbole G, Woodford N.

J Antimicrob Chemother. 2017 Jan;72(1):145-152. Epub 2016 Sep 27.

PMID:
27678285
47.

Identifying lineage effects when controlling for population structure improves power in bacterial association studies.

Earle SG, Wu CH, Charlesworth J, Stoesser N, Gordon NC, Walker TM, Spencer CCA, Iqbal Z, Clifton DA, Hopkins KL, Woodford N, Smith EG, Ismail N, Llewelyn MJ, Peto TE, Crook DW, McVean G, Walker AS, Wilson DJ.

Nat Microbiol. 2016 Apr 4;1:16041. doi: 10.1038/nmicrobiol.2016.41.

48.

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings.

Feasey NA, Hadfield J, Keddy KH, Dallman TJ, Jacobs J, Deng X, Wigley P, Barquist L, Langridge GC, Feltwell T, Harris SR, Mather AE, Fookes M, Aslett M, Msefula C, Kariuki S, Maclennan CA, Onsare RS, Weill FX, Le Hello S, Smith AM, McClelland M, Desai P, Parry CM, Cheesbrough J, French N, Campos J, Chabalgoity JA, Betancor L, Hopkins KL, Nair S, Humphrey TJ, Lunguya O, Cogan TA, Tapia MD, Sow SO, Tennant SM, Bornstein K, Levine MM, Lacharme-Lora L, Everett DB, Kingsley RA, Parkhill J, Heyderman RS, Dougan G, Gordon MA, Thomson NR.

Nat Genet. 2016 Oct;48(10):1211-1217. doi: 10.1038/ng.3644. Epub 2016 Aug 22. Erratum in: Nat Genet. 2017 Mar 30;49(4):651.

49.

First detection of a carbapenemase-producing Enterobacteriaceae in Iceland.

Helgason KO, Jelle AE, Gudlaugsson O, Edvardsson V, Findlay J, Hopkins KL, Woodford N, Samuelsen Ø, Hardarson HS.

J Glob Antimicrob Resist. 2016 Sep;6:73-74. doi: 10.1016/j.jgar.2016.04.002. Epub 2016 May 2. No abstract available.

PMID:
27530843
50.

Enhanced surveillance of carbapenemase-producing Gram-negative bacteria to support national and international prevention and control efforts.

Freeman R, Ironmonger D, Puleston R, Hopkins KL, Welfare W, Hope R, Staves P, Shemko M, Hopkins S, Cleary P, Patel B, Muller-Pebody B, Li X, Alvarez-Buylla A, Hawkey PM, Johnson AP, Woodford N, Oliver I.

Clin Microbiol Infect. 2016 Oct;22(10):896-897. doi: 10.1016/j.cmi.2016.07.020. Epub 2016 Jul 27. No abstract available.

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