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Items: 1 to 50 of 825

1.

Role of JNK, MEK and adenylyl cyclase signalling in speed and directionality of enteric neural crest-derived cells.

Hao MM, Bergner AJ, Nguyen HTH, Dissanayake P, Burnett LE, Hopkins CD, Zeng K, Young HM, Stamp LA.

Dev Biol. 2019 Jul 12. pii: S0012-1606(19)30197-6. doi: 10.1016/j.ydbio.2019.07.007. [Epub ahead of print]

PMID:
31306639
2.

A review of the literature on family decision-making at end of life precipitating hospital admission.

Procter S, Ooi M, Hopkins C, Moore G.

Br J Nurs. 2019 Jul 11;28(13):878-884. doi: 10.12968/bjon.2019.28.13.878.

PMID:
31303037
3.

Cognitive Impairment after Kidney Transplant: a Hidden Consequence of Depression?

Moulton CD, Tharmaraja T, Dumbrill JL, Hopkins CWP.

J Am Soc Nephrol. 2019 Jul 12. pii: ASN.2019030317. doi: 10.1681/ASN.2019030317. [Epub ahead of print] No abstract available.

PMID:
31300485
4.

What is the most appropriate treatment for chronic rhinosinusitis?

Walker A, Philpott C, Hopkins C.

Postgrad Med J. 2019 Jul 10. pii: postgradmedj-2019-136519. doi: 10.1136/postgradmedj-2019-136519. [Epub ahead of print] Review.

PMID:
31292281
5.

Early weight loss in a standalone mHealth intervention predicting treatment success.

Patel ML, Hopkins CM, Bennett GG.

Obes Sci Pract. 2019 Apr 3;5(3):231-237. doi: 10.1002/osp4.329. eCollection 2019 Jun.

6.

Chronic Rhinosinusitis with Nasal Polyps.

Hopkins C.

N Engl J Med. 2019 Jul 4;381(1):55-63. doi: 10.1056/NEJMcp1800215. Review. No abstract available.

PMID:
31269366
7.

Transmission of HIV infection by severe bites.

Thomas MG, Hopkins CJ, Luey CE.

Int J STD AIDS. 2019 Jun 21:956462419844852. doi: 10.1177/0956462419844852. [Epub ahead of print] No abstract available.

PMID:
31226915
8.

Critical developments of 2018: A review of the literature from selected topics in transfusion. A committee report from the AABB's Clinical Transfusion Medicine Committee.

Cohn CS, Allen ES, Cushing MM, Dunbar NM, Friedman DF, Goel R, Heddle N, Hopkins CK, Klapper E, Perumbeti A, Ramsey G, Raval JS, Schwartz J, Shaz BH, Spinella PC, Pagano MB.

Transfusion. 2019 May 30. doi: 10.1111/trf.15348. [Epub ahead of print]

PMID:
31148175
9.

The association between selective serotonin reuptake inhibitors and glycemia: a systematic review and meta-analysis of randomized controlled trials.

Tharmaraja T, Stahl D, Hopkins CWP, Persaud SJ, Jones PM, Ismail K, Moulton CD.

Psychosom Med. 2019 May 6. doi: 10.1097/PSY.0000000000000707. [Epub ahead of print]

PMID:
31136376
10.

Exploring the association between ingestion of foods with higher potential salicylate content and symptom exacerbation in chronic rhinosinusitis. Data from the National Chronic Rhinosinusitis Epidemiology Study.

Philpott CM, Smith R, Davies-Husband CR, Erskine S, Clark A, Welch A, Hopkins C, Carrie S, Ray J, Sunkaraneni V, Kara N, Kumar N, Robertson A, Anari S, Almeyda R, Wilson A.

Rhinology. 2019 May 23. doi: 10.4193/Rhin19.027. [Epub ahead of print]

PMID:
31120456
11.

EUFOREA consensus on biologics for CRSwNP with or without asthma.

Fokkens WJ, Lund V, Bachert C, Mullol J, Bjermer L, Bousquet J, Canonica GW, Deneyer L, Desrosiers M, Diamant Z, Han J, Heffler E, Hopkins C, Jankowski R, Joos G, Knill A, Lee J, Lee SE, Mariƫn G, Pugin B, Senior B, Seys SF, Hellings PW.

Allergy. 2019 May 15. doi: 10.1111/all.13875. [Epub ahead of print] Review.

PMID:
31090937
12.

Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: study protocol for the MACRO randomised controlled trial.

Philpott C, le Conte S, Beard D, Cook J, Sones W, Morris S, Clarke CS, Thomas M, Little P, Vennik J, Lund V, Blackshaw H, Schilder A, Durham S, Denaxas S, Carpenter J, Boardman J, Hopkins C; MACRO programme team.

Trials. 2019 Apr 29;20(1):246. doi: 10.1186/s13063-019-3314-7.

13.

Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics.

Aretz CD, Vadukoot AK, Hopkins CR.

J Med Chem. 2019 May 9. doi: 10.1021/acs.jmedchem.8b01891. [Epub ahead of print]

PMID:
31034224
14.

Chronic rhinosinusitis: a qualitative study of patient views and experiences of current management in primary and secondary care.

Vennik J, Eyles C, Thomas M, Hopkins C, Little P, Blackshaw H, Schilder A, Savage I, Philpott CM.

BMJ Open. 2019 Apr 23;9(4):e022644. doi: 10.1136/bmjopen-2018-022644.

15.

Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme).

Blackshaw H, Vennik J, Philpott C, Thomas M, Eyles C, Carpenter J, Clarke CS, Morris S, Schilder A, Lund V, Little P, Durham S, Denaxas S, Williamson E, Beard D, Cook J, Le Conte S, Airey K, Boardman J, Hopkins C.

Trials. 2019 Apr 23;20(1):230. doi: 10.1186/s13063-019-3318-3.

16.

Patient Advisory Board for Chronic Rhinosinusitis - A EUFOREA initiative.

Pugin B, Deneyer L, Bachert C, Alobid I, Bousquet J, De Carlo G, Fokkens WJ, Gane S, Hopkins C, Holzmeister C, Langdon C, Lourijsen ES, Lund VJ, Marien G, Mavris M, Mullol J, Pereira-Perez C, Tomazic PV, Vanderveken O, Hellings PW, Seys SF.

Rhinology. 2019 Apr 9. doi: 10.4193/Rhin19.012. [Epub ahead of print]

PMID:
30963145
17.

Analysis of the South Australian Aboriginal population using the Global AIMs Nano ancestry test.

Hopkins C, Taylor D, Hill K, Henry J.

Forensic Sci Int Genet. 2019 Jul;41:34-41. doi: 10.1016/j.fsigen.2019.03.020. Epub 2019 Mar 23.

PMID:
30952105
18.

Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases.

Sharma S, Hopkins CR.

J Med Chem. 2019 Apr 17. doi: 10.1021/acs.jmedchem.8b01954. [Epub ahead of print]

PMID:
30943030
19.

Epidemiology, management and outcomes of large and small native joint septic arthritis in adults.

McBride S, Mowbray J, Caughey W, Wong E, Luey C, Siddiqui A, Alexander Z, Playle V, Askelund T, Hopkins C, Quek N, Ross K, Orec R, Mistry D, Coomarasamy C, Holland D.

Clin Infect Dis. 2019 Apr 3. pii: ciz265. doi: 10.1093/cid/ciz265. [Epub ahead of print]

PMID:
30941403
20.

Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records.

Williamson E, Denaxas S, Morris S, Clarke CS, Thomas M, Evans H, Direk K, Gonzalez-Izquierdo A, Little P, Lund V, Blackshaw H, Schilder A, Philpott C, Hopkins C, Carpenter J; MACRO programme team.

Rhinology. 2019 Mar 30. doi: 10.4193/Rhin18.237. [Epub ahead of print]

PMID:
30928998
21.

VU0810464, a non-urea G protein-gated inwardly rectifying K+ (Kir 3/GIRK) channel activator, exhibits enhanced selectivity for neuronal Kir 3 channels and reduces stress-induced hyperthermia in mice.

Vo BN, Abney KK, Anderson A, Marron Fernandez de Velasco E, Benneyworth MA, Daniels JS, Morrison RD, Hopkins CR, Weaver CD, Wickman K.

Br J Pharmacol. 2019 Jul;176(13):2238-2249. doi: 10.1111/bph.14671. Epub 2019 May 30.

PMID:
30924523
22.

Correction to Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models.

Abney KK, Bubser M, Du Y, Kozek KA, Bridges TM, Lindsley CW, Daniels JS, Morrison RD, Wickman K, Hopkins CR, Jones CK, Weaver CD.

ACS Chem Neurosci. 2019 May 15;10(5):2621. doi: 10.1021/acschemneuro.9b00165. Epub 2019 Mar 26. No abstract available.

PMID:
30912639
23.

Framing the failure of medical implants: Media representations of the ASR hip replacements in the UK.

Maniatopoulos G, Hopkins C, Joyce TJ, Brittain K.

Health Expect. 2019 Jun;22(3):518-527. doi: 10.1111/hex.12877. Epub 2019 Mar 19.

24.

Discovery of VU2957 (Valiglurax): An mGlu4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease.

Panarese JD, Engers DW, Wu YJ, Bronson JJ, Macor JE, Chun A, Rodriguez AL, Felts AS, Engers JL, Loch MT, Emmitte KA, Castelhano AL, Kates MJ, Nader MA, Jones CK, Blobaum AL, Conn PJ, Niswender CM, Hopkins CR, Lindsley CW.

ACS Med Chem Lett. 2018 Oct 16;10(3):255-260. doi: 10.1021/acsmedchemlett.8b00426. eCollection 2019 Mar 14.

PMID:
30891122
25.

Discovery and Characterization of 2-Nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)- N-(pyridin-4-ylmethyl)anilines as Novel Inhibitors of the Aedes aegypti Kir1 ( AeKir1) Channel.

Aretz CD, Morwitzer MJ, Sanford AG, Hogan AM, Portillo MV, Kharade SV, Kramer M, McCarthey JB, Trigueros RR, Piermarini PM, Denton JS, Hopkins CR.

ACS Infect Dis. 2019 Jun 14;5(6):917-931. doi: 10.1021/acsinfecdis.8b00368. Epub 2019 Mar 15.

PMID:
30832472
26.

Out of Sight, Out of Mind: The Limitations of the Hospital Anxiety and Depression Scale in Inflammatory Bowel Disease.

Moulton CD, Hopkins CWP, Mohamedali Z, Powell N.

Inflamm Bowel Dis. 2019 Jul 17;25(8):e100. doi: 10.1093/ibd/izz034. No abstract available.

PMID:
30824907
27.

Comparing Self-Monitoring Strategies for Weight Loss in a Smartphone App: Randomized Controlled Trial.

Patel ML, Hopkins CM, Brooks TL, Bennett GG.

JMIR Mhealth Uhealth. 2019 Feb 28;7(2):e12209. doi: 10.2196/12209.

28.

EPOS2020: development strategy and goals for the latest European Position Paper on Rhinosinusitis.

Fokkens W, Desrosiers M, Harvey R, Hopkins C, Mullol J, Philpott C, Alobid I, Anselmo-Lima WT, Bachert C, Baroody F, Bernal-Sprekelsen M, von Buchwald C, Cervin A, Cohen N, Constantinidis J, De Gabory L, Douglas R, Gevaert P, Hafner A, Hellings P, Joos G, Kalogjera L, Kern R, Knill A, Kocks J, Landis BN, Limpens J, Lebeer S, Lourenco O, Matricardi PM, Meco C, O Mahony L, Reitsma S, Ryan D, Schlosser R, Senior B, Smith T, Teeling T, Tomazic PV, Toppila-Salmi S, Wang DY, Wang D, Zhang L, Lund V.

Rhinology. 2019 Jun 1;57(3):162-168. doi: 10.4193/Rhin17.253.

PMID:
30810118
29.

Depression in inflammatory bowel disease: risk factor, prodrome or extraintestinal manifestation?

Moulton CD, Norton C, Powell N, Mohamedali Z, Hopkins CWP.

Gut. 2019 Feb 26. pii: gutjnl-2019-318444. doi: 10.1136/gutjnl-2019-318444. [Epub ahead of print] No abstract available.

PMID:
30808645
30.

Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators.

Sharma S, Kozek KA, Abney KK, Kumar S, Gautam N, Alnouti Y, David Weaver C, Hopkins CR.

Bioorg Med Chem Lett. 2019 Mar 15;29(6):791-796. doi: 10.1016/j.bmcl.2019.01.027. Epub 2019 Jan 23.

PMID:
30718161
31.

A mixed-methods study of coping and depression in adolescent girls with polycystic ovary syndrome.

Hopkins CS, Kimble LP, Hodges HF, Koci AF, Mills BB.

J Am Assoc Nurse Pract. 2019 Mar;31(3):189-197. doi: 10.1097/JXX.0000000000000125.

PMID:
30681649
32.

Cost-effectiveness of Coblation compared with cold steel tonsillectomies in the UK.

Guest JF, Rana K, Hopkins C.

J Laryngol Otol. 2018 Dec;132(12):1119-1127. doi: 10.1017/S0022215118002220.

PMID:
30674367
33.

National prospective observational study of inpatient management of adults with epistaxis - a National Trainee Research Collaborative delivered investigation.

INTEGRATE (UK National ENT research trainee network) on its behalf: , Mehta N, Stevens K, Smith ME, Williams RJ, Ellis M, Hardman JC, Hopkins C.

Rhinology. 2019 Jun 1;57(3):180-189. doi: 10.4193/Rhin18.239.

PMID:
30610832
34.

Management strategies for chronic rhinosinusitis: a qualitative study of GP and ENT specialist views of current practice in the UK.

Vennik J, Eyles C, Thomas M, Hopkins C, Little P, Blackshaw H, Schilder A, Boardman J, Philpott CM.

BMJ Open. 2018 Dec 19;8(12):e022643. doi: 10.1136/bmjopen-2018-022643.

35.

Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903.

Sharma SH, Pablo JL, Montesinos MS, Greka A, Hopkins CR.

Bioorg Med Chem Lett. 2019 Jan 15;29(2):155-159. doi: 10.1016/j.bmcl.2018.12.007. Epub 2018 Dec 4.

PMID:
30538066
36.

The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu4 PAM development candidate.

Panarese JD, Engers DW, Wu YJ, Guernon JM, Chun A, Gregro AR, Bender AM, Capstick RA, Wieting JM, Bronson JJ, Macor JE, Westphal R, Soars M, Engers JE, Felts AS, Rodriguez AL, Emmitte KA, Jones CK, Blobaum AL, Conn PJ, Niswender CM, Hopkins CR, Lindsley CW.

Bioorg Med Chem Lett. 2019 Jan 15;29(2):342-346. doi: 10.1016/j.bmcl.2018.10.050. Epub 2018 Nov 1.

PMID:
30503632
37.

Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models.

Abney KK, Bubser M, Du Y, Kozek KA, Bridges TM, Linsdley CW, Daniels JS, Morrison RD, Wickman K, Hopkins CR, Jones CK, Weaver CD.

ACS Chem Neurosci. 2019 Mar 20;10(3):1294-1299. doi: 10.1021/acschemneuro.8b00370. Epub 2018 Dec 11. Erratum in: ACS Chem Neurosci. 2019 May 15;10(5):2621.

PMID:
30474955
38.

Pharmacological Inhibition of Inward Rectifier Potassium Channels Induces Lethality in Larval Aedes aegypti.

Rusconi Trigueros R, Hopkins CR, Denton JS, Piermarini PM.

Insects. 2018 Nov 15;9(4). pii: E163. doi: 10.3390/insects9040163.

39.

Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets.

Santos PT, O'Brien CE, Chen MW, Hopkins CD, Adams S, Kulikowicz E, Singh R, Koehler RC, Martin LJ, Lee JK.

J Am Heart Assoc. 2018 Oct 16;7(20):e009415. doi: 10.1161/JAHA.118.009415.

40.

Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu4).

Bollinger SR, Engers DW, Panarese JD, West M, Engers JL, Loch MT, Rodriguez AL, Blobaum AL, Jones CK, Thompson Gray A, Conn PJ, Lindsley CW, Niswender CM, Hopkins CR.

J Med Chem. 2019 Jan 10;62(1):342-358. doi: 10.1021/acs.jmedchem.8b00994. Epub 2018 Oct 10.

PMID:
30247901
41.

Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue.

Zhao Y, Uduman M, Siu JHY, Tull TJ, Sanderson JD, Wu YB, Zhou JQ, Petrov N, Ellis R, Todd K, Chavele KM, Guesdon W, Vossenkamper A, Jassem W, D'Cruz DP, Fear DJ, John S, Scheel-Toellner D, Hopkins C, Moreno E, Woodman NL, Ciccarelli F, Heck S, Kleinstein SH, Bemark M, Spencer J.

Nat Commun. 2018 Sep 21;9(1):3857. doi: 10.1038/s41467-018-06089-1.

42.

Outcome Measures in Chronic Rhinosinusitis.

Ting F, Hopkins C.

Curr Otorhinolaryngol Rep. 2018;6(3):271-275. doi: 10.1007/s40136-018-0215-3. Epub 2018 Aug 16. Review.

43.

Weight-Related Terms Differentially Affect Self-Efficacy and Perception of Obesity.

Hopkins CM, Bennett GG.

Obesity (Silver Spring). 2018 Sep;26(9):1405-1411. doi: 10.1002/oby.22255.

PMID:
30226011
44.

Topical and systemic antifungal therapy for chronic rhinosinusitis.

Head K, Sharp S, Chong LY, Hopkins C, Philpott C.

Cochrane Database Syst Rev. 2018 Sep 10;9:CD012453. doi: 10.1002/14651858.CD012453.pub2. Review.

PMID:
30199594
45.

Inward rectifier potassium (Kir) channels in the soybean aphid Aphis glycines: Functional characterization, pharmacology, and toxicology.

Piermarini PM, Inocente EA, Acosta N, Hopkins CR, Denton JS, Michel AP.

J Insect Physiol. 2018 Oct;110:57-65. doi: 10.1016/j.jinsphys.2018.09.001. Epub 2018 Sep 6.

PMID:
30196125
46.

Nerve root block versus surgery (NERVES) for the treatment of radicular pain secondary to a prolapsed intervertebral disc herniation: study protocol for a multi-centre randomised controlled trial.

Wilby MJ, Hopkins C, Bedson E, Howlin S, Burnside G, Conroy EJ, Hughes DA, Sharma M, Marson A, Clark SR, Williamson P.

Trials. 2018 Sep 5;19(1):475. doi: 10.1186/s13063-018-2677-5.

47.

Physical Activity and Future Physical Function: Data From the Osteoarthritis Initiative.

Hopkins C.

J Aging Phys Act. 2019 Jun 1;27(3):367-370. doi: 10.1123/japa.2018-0136. Epub 2018 Nov 19.

PMID:
30160572
48.

Rhinosinusitis symptoms, smoking and COPD: Prevalence and associations.

Caminha GP, Pizzichini E, Lubianca Neto JF, Hopkins C, Moreira JDS, Pizzichini MMM.

Clin Otolaryngol. 2018 Dec;43(6):1560-1565. doi: 10.1111/coa.13215. Epub 2018 Sep 19.

PMID:
30152142
49.

Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels.

Kozek KA, Du Y, Sharma S, Prael FJ 3rd, Spitznagel BD, Kharade SV, Denton JS, Hopkins CR, Weaver CD.

ACS Chem Neurosci. 2019 Jan 16;10(1):358-370. doi: 10.1021/acschemneuro.8b00287. Epub 2018 Sep 13.

PMID:
30136838
50.

Missed opportunities for earlier diagnosis of human immunodeficiency virus infection among adults presenting to Auckland District Health Board hospital services.

Hopkins C, Reid M, Gilmour J, Werder S, Briggs S.

Intern Med J. 2019 Apr;49(4):495-501. doi: 10.1111/imj.14073.

PMID:
30091194

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