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Knowledge About Oral PrEP Among Transgender Women in New York City.

Rael CT, Martinez M, Giguere R, Bockting W, MacCrate C, Mellman W, Valente P, Greene GJ, Sherman SG, Footer KHA, D'Aquila R, Carballo-Diéguez A, Hope TJ.

AIDS Behav. 2019 Jul 6. doi: 10.1007/s10461-019-02584-8. [Epub ahead of print]


Co- but not Sequential Infection of DCs Boosts Their HIV-Specific CTL-Stimulatory Capacity.

Schönfeld M, Knackmuss U, Chandorkar P, Hörtnagl P, Hope TJ, Moris A, Bellmann-Weiler R, Lass-Flörl C, Posch W, Wilflingseder D.

Front Immunol. 2019 May 24;10:1123. doi: 10.3389/fimmu.2019.01123. eCollection 2019.


Cervical and systemic concentrations of long acting hormonal contraceptive (LARC) progestins depend on delivery method: Implications for the study of HIV transmission.

Buckner LR, Drobnis EZ, Augustine MS, Rogers LK, Akers J, Mott PD, Hope TJ, Quayle AJ, Schust DJ.

PLoS One. 2019 May 16;14(5):e0214152. doi: 10.1371/journal.pone.0214152. eCollection 2019.


Increased mucosal neutrophil survival is associated with altered microbiota in HIV infection.

Hensley-McBain T, Wu MC, Manuzak JA, Cheu RK, Gustin A, Driscoll CB, Zevin AS, Miller CJ, Coronado E, Smith E, Chang J, Gale M Jr, Somsouk M, Burgener AD, Hunt PW, Hope TJ, Collier AC, Klatt NR.

PLoS Pathog. 2019 Apr 11;15(4):e1007672. doi: 10.1371/journal.ppat.1007672. eCollection 2019 Apr.


Defining characteristics of genital health in South African adolescent girls and young women at high risk for HIV infection.

Dabee S, Barnabas SL, Lennard KS, Jaumdally SZ, Gamieldien H, Balle C, Happel AU, Murugan BD, Williamson AL, Mkhize N, Dietrich J, Lewis DA, Chiodi F, Hope TJ, Shattock R, Gray G, Bekker LG, Jaspan HB, Passmore JS.

PLoS One. 2019 Apr 4;14(4):e0213975. doi: 10.1371/journal.pone.0213975. eCollection 2019.


Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models.

Pollara J, Jones DI, Huffman T, Edwards RW, Dennis M, Li SH, Jha S, Goodman D, Kumar A, LaBranche CC, Montefiori DC, Fouda GG, Hope TJ, Tomaras GD, Staats HF, Ferrari G, Permar SR.

J Virol. 2019 May 1;93(10). pii: e02119-18. doi: 10.1128/JVI.02119-18. Print 2019 May 15.


Effects of three long-acting reversible contraceptive methods on HIV target cells in the human uterine cervix and peripheral blood.

Li L, Zhou J, Wang W, Huang L, Tu J, Baiamonte L, Stark M, Mills M, Hope TJ, Drobnis EZ, Quayle AJ, Schust DJ.

Reprod Biol Endocrinol. 2019 Feb 22;17(1):26. doi: 10.1186/s12958-019-0469-8.


Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1.

Tay MZ, Kunz EL, Deal A, Zhang L, Seaton KE, Rountree W, Eudailey JA, Heptinstall J, McRaven MD, Matias E, McGuire E, Yates NL, Perez LG, Montefiori DC, Overman RG, Hope TJ, Shen X, Kalilani L, Fouda GG, Tomaras GD, Permar SR.

J Virol. 2019 Mar 21;93(7). pii: e02084-18. doi: 10.1128/JVI.02084-18. Print 2019 Apr 1.


Qualitative Consumer Research on Acceptance of Long-Acting Pre-Exposure Prophylaxis Products Among Men Having Sex with Men and Medical Practitioners in the United States.

Calder BJ, Schieffer RJ, Bryndza Tfaily E, D'Aquila R, Greene GJ, Carballo-Diéguez A, Giguere R, Kiser PF, Hope TJ.

AIDS Res Hum Retroviruses. 2018 Oct;34(10):849-856. doi: 10.1089/AID.2018.0214.


Inflammation weakens HIV prevention.

Hope TJ.

Nat Med. 2018 Apr 10;24(4):384-385. doi: 10.1038/nm.4534. No abstract available.


HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.

Wills S, Hwang KK, Liu P, Dennison SM, Tay MZ, Shen X, Pollara J, Lucas JT, Parks R, Rerks-Ngarm S, Pitisuttithum P, Nitayapan S, Kaewkungwal J, Thomas R, Kim JH, Michael NL, Robb ML, McRaven M, Montefiori DC, Hope TJ, Liao HX, Moody MA, Ferrari G, Haynes BF, Alam SM, Bonsignori M, Tomaras GD.

J Virol. 2018 Mar 14;92(7). pii: e01552-17. doi: 10.1128/JVI.01552-17. Print 2018 Apr 1.


Converging epidemics of sexually transmitted infections and bacterial vaginosis in southern African female adolescents at risk of HIV.

Barnabas SL, Dabee S, Passmore JS, Jaspan HB, Lewis DA, Jaumdally SZ, Gamieldien H, Masson L, Muller E, Maseko VD, Mkhize N, Mbulawa Z, Williamson AL, Gray CM, Hope TJ, Chiodi F, Dietrich J, Gray G, Bekker LG; Women’s Initiative in Sexual Health (WISH) study team.

Int J STD AIDS. 2018 May;29(6):531-539. doi: 10.1177/0956462417740487. Epub 2017 Dec 4.


Distinguishing signal from autofluorescence in cryogenic correlated light and electron microscopy of mammalian cells.

Carter SD, Mageswaran SK, Farino ZJ, Mamede JI, Oikonomou CM, Hope TJ, Freyberg Z, Jensen GJ.

J Struct Biol. 2018 Jan;201(1):15-25. doi: 10.1016/j.jsb.2017.10.009. Epub 2017 Oct 25.


Early cytoplasmic uncoating is associated with infectivity of HIV-1.

Mamede JI, Cianci GC, Anderson MR, Hope TJ.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7169-E7178. doi: 10.1073/pnas.1706245114. Epub 2017 Aug 7.


Long-term direct visualization of passively transferred fluorophore-conjugated antibodies.

Schneider JR, Carias AM, Bastian AR, Cianci GC, Kiser PF, Veazey RS, Hope TJ.

J Immunol Methods. 2017 Nov;450:66-72. doi: 10.1016/j.jim.2017.07.009. Epub 2017 Aug 2.


HIV-1 selectively targets gut-homing CCR6+CD4+ T cells via mTOR-dependent mechanisms.

Planas D, Zhang Y, Monteiro P, Goulet JP, Gosselin A, Grandvaux N, Hope TJ, Fassati A, Routy JP, Ancuta P.

JCI Insight. 2017 Aug 3;2(15). pii: 93230. doi: 10.1172/jci.insight.93230. eCollection 2017 Aug 3.


HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights.

Shacklett BL, Derdeyn CA, Folayan MO, Landovitz RJ, Anthony C, Behrens AJ, Hope TJ, Landais E, Leal L, Marrazzo JM, Morris L, Mugo N, Ngure K, Noseda V, Ranasinghe S, Tully DC, Voronin Y, Warren M, Wibmer CK, Xie IY, Scarlatti G, Thyagarajan B.

AIDS Res Hum Retroviruses. 2017 Aug;33(8):749-759. doi: 10.1089/AID.2017.0125. Epub 2017 Jul 26.


Upcoming Implementation of NIH Funding Caps Invites Researcher Feedback.

Hope TJ.

AIDS Res Hum Retroviruses. 2017 Jun;33(6):iii. doi: 10.1089/aid.2017.29004.tjh. No abstract available.


Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.

Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, Druz A, Feng Y, Joyce MG, Louder MK, O'Dell S, Oliver C, Pancera M, Connors M, Hope TJ, Kepler TB, Wyatt RT, Ward AB, Georgiev IS, Kwong PD, Mascola JR, Binley JM.

Immunity. 2017 May 16;46(5):777-791.e10. doi: 10.1016/j.immuni.2017.04.011.


Colposcopic imaging using visible-light optical coherence tomography.

Duan L, McRaven MD, Liu W, Shu X, Hu J, Sun C, Veazey RS, Hope TJ, Zhang HF.

J Biomed Opt. 2017 May 1;22(5):56003. doi: 10.1117/1.JBO.22.5.056003.


A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle.

Xiao S, Coppeta JR, Rogers HB, Isenberg BC, Zhu J, Olalekan SA, McKinnon KE, Dokic D, Rashedi AS, Haisenleder DJ, Malpani SS, Arnold-Murray CA, Chen K, Jiang M, Bai L, Nguyen CT, Zhang J, Laronda MM, Hope TJ, Maniar KP, Pavone ME, Avram MJ, Sefton EC, Getsios S, Burdette JE, Kim JJ, Borenstein JT, Woodruff TK.

Nat Commun. 2017 Mar 28;8:14584. doi: 10.1038/ncomms14584.


Can a Traditional Chinese Medicine Contribute to a Cure for HIV?

Hope TJ.

AIDS Res Hum Retroviruses. 2017 Feb;33(2):89. doi: 10.1089/aid.2017.29001.hop. No abstract available.


Associations of the vaginal microbiota with HIV infection, bacterial vaginosis, and demographic factors.

Chehoud C, Stieh DJ, Bailey AG, Laughlin AL, Allen SA, McCotter KL, Sherrill-Mix SA, Hope TJ, Bushman FD.

AIDS. 2017 Apr 24;31(7):895-904. doi: 10.1097/QAD.0000000000001421.


Preferences for Long-Acting Pre-exposure Prophylaxis (PrEP), Daily Oral PrEP, or Condoms for HIV Prevention Among U.S. Men Who Have Sex with Men.

Greene GJ, Swann G, Fought AJ, Carballo-Diéguez A, Hope TJ, Kiser PF, Mustanski B, D'Aquila RT.

AIDS Behav. 2017 May;21(5):1336-1349. doi: 10.1007/s10461-016-1565-9.


Increases in Endogenous or Exogenous Progestins Promote Virus-Target Cell Interactions within the Non-human Primate Female Reproductive Tract.

Carias AM, Allen SA, Fought AJ, Kotnik Halavaty K, Anderson MR, Jimenez ML, McRaven MD, Gioia CJ, Henning TR, Kersh EN, Smith JM, Pereira LE, Butler K, McNicholl SJ, Hendry RM, Kiser PF, Veazey RS, Hope TJ.

PLoS Pathog. 2016 Sep 22;12(9):e1005885. doi: 10.1371/journal.ppat.1005885. eCollection 2016 Sep.


Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.

Tay MZ, Liu P, Williams LD, McRaven MD, Sawant S, Gurley TC, Xu TT, Dennison SM, Liao HX, Chenine AL, Alam SM, Moody MA, Hope TJ, Haynes BF, Tomaras GD.

PLoS Pathog. 2016 Aug 31;12(8):e1005817. doi: 10.1371/journal.ppat.1005817. eCollection 2016 Aug.


KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection.

Dharan A, Talley S, Tripathi A, Mamede JI, Majetschak M, Hope TJ, Campbell EM.

PLoS Pathog. 2016 Jun 21;12(6):e1005700. doi: 10.1371/journal.ppat.1005700. eCollection 2016 Jun.


Changes in HIV-1 Capsid Stability Induced by Common Cytotoxic-T-Lymphocyte-Driven Viral Sequence Mutations.

Schommers P, Martrus G, Matschl U, Sirignano M, Lütgehetmann M, Richert L, Hope TJ, Fätkenheuer G, Altfeld M.

J Virol. 2016 Jul 27;90(16):7579-7586. doi: 10.1128/JVI.00867-16. Print 2016 Aug 15.


Transcriptional Profiling of Human Endocervical Tissues Reveals Distinct Gene Expression in the Follicular and Luteal Phases of the Menstrual Cycle.

Yildiz-Arslan S, Coon JS, Hope TJ, Kim JJ.

Biol Reprod. 2016 Jun;94(6):138. doi: 10.1095/biolreprod.116.140327. Epub 2016 May 11.


Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission.

Cheeseman HM, Carias AM, Evans AB, Olejniczak NJ, Ziprin P, King DF, Hope TJ, Shattock RJ.

PLoS One. 2016 May 10;11(5):e0154656. doi: 10.1371/journal.pone.0154656. eCollection 2016.


Glycogen Levels in Undiluted Genital Fluid and Their Relationship to Vaginal pH, Estrogen, and Progesterone.

Mirmonsef P, Hotton AL, Gilbert D, Gioia CJ, Maric D, Hope TJ, Landay AL, Spear GT.

PLoS One. 2016 Apr 19;11(4):e0153553. doi: 10.1371/journal.pone.0153553. eCollection 2016.


Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques.

Stieh DJ, Matias E, Xu H, Fought AJ, Blanchard JL, Marx PA, Veazey RS, Hope TJ.

Cell Host Microbe. 2016 Apr 13;19(4):529-40. doi: 10.1016/j.chom.2016.03.005.


Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16.

Gunn B, Schneider J, Shansab M, Bastian AR, Fahrbach K, Smith A 4th, Mahan A, Karim M, Licht A, Zvonar I, Tedesco J, Anderson M, Chapel A, Suscovich T, Malaspina D, Streeck H, Walker BD, Kim A, Lauer G, Altfeld M, Pillai S, Szleifer I, Kelleher NL, Kiser PF, Hope TJ, Alter G.

Mucosal Immunol. 2016 Nov;9(6):1549-1558. doi: 10.1038/mi.2016.8. Epub 2016 Mar 9.


Prevention of SHIV transmission by topical IFN-β treatment.

Veazey RS, Pilch-Cooper HA, Hope TJ, Alter G, Carias AM, Sips M, Wang X, Rodriguez B, Sieg SF, Reich A, Wilkinson P, Cameron MJ, Lederman MM.

Mucosal Immunol. 2016 Nov;9(6):1528-1536. doi: 10.1038/mi.2015.146. Epub 2016 Feb 3.


TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction.

Imam S, Talley S, Nelson RS, Dharan A, O'Connor C, Hope TJ, Campbell EM.

J Virol. 2016 Jan 13;90(7):3400-10. doi: 10.1128/JVI.03033-15.


Detection and Tracking of Dual-Labeled HIV Particles Using Wide-Field Live Cell Imaging to Follow Viral Core Integrity.

Mamede JI, Hope TJ.

Methods Mol Biol. 2016;1354:49-59. doi: 10.1007/978-1-4939-3046-3_4.


VIROLOGY. Visualizing trans-infection.

Hope TJ.

Science. 2015 Oct 30;350(6260):511-2. doi: 10.1126/science.aad5409. No abstract available.


A Shot in the Arm for HIV Prevention? Recent Successes and Critical Thresholds.

Hope TJ, Marrazzo JM.

AIDS Res Hum Retroviruses. 2015 Nov;31(11):1055-9. doi: 10.1089/AID.2015.0310. Review.


HIV-1 capsid: the multifaceted key player in HIV-1 infection.

Campbell EM, Hope TJ.

Nat Rev Microbiol. 2015 Aug;13(8):471-83. doi: 10.1038/nrmicro3503. Review.


Randomized Cross-Sectional Study to Compare HIV-1 Specific Antibody and Cytokine Concentrations in Female Genital Secretions Obtained by Menstrual Cup and Cervicovaginal Lavage.

Archary D, Liebenberg LJ, Werner L, Tulsi S, Majola N, Naicker N, Dlamini S, Hope TJ, Samsunder N, Abdool Karim SS, Morris L, Passmore JA, Garrett NJ.

PLoS One. 2015 Jul 6;10(7):e0131906. doi: 10.1371/journal.pone.0131906. eCollection 2015.


Impact of Nucleoporin-Mediated Chromatin Localization and Nuclear Architecture on HIV Integration Site Selection.

Wong RW, Mamede JI, Hope TJ.

J Virol. 2015 Oct;89(19):9702-5. doi: 10.1128/JVI.01669-15. Epub 2015 Jul 1. Review.


Fluorescent image analysis of HIV-1 and HIV-2 uncoating kinetics in the presence of old world monkey TRIM5α.

Takeda E, Kono K, Hulme AE, Hope TJ, Nakayama EE, Shioda T.

PLoS One. 2015 Mar 24;10(3):e0121199. doi: 10.1371/journal.pone.0121199. eCollection 2015.


Visualization of HIV-1 interactions with penile and foreskin epithelia: clues for female-to-male HIV transmission.

Dinh MH, Anderson MR, McRaven MD, Cianci GC, McCoombe SG, Kelley ZL, Gioia CJ, Fought AJ, Rademaker AW, Veazey RS, Hope TJ.

PLoS Pathog. 2015 Mar 6;11(3):e1004729. doi: 10.1371/journal.ppat.1004729. eCollection 2015 Mar.


Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells.

Hulme AE, Kelley Z, Foley D, Hope TJ.

J Virol. 2015 May;89(10):5350-61. doi: 10.1128/JVI.00476-15. Epub 2015 Mar 4.


Characterization of the Influence of Semen-Derived Enhancer of Virus Infection on the Interaction of HIV-1 with Female Reproductive Tract Tissues.

Allen SA, Carias AM, Anderson MR, Okocha EA, Benning L, McRaven MD, Kelley ZL, Lurain J, Veazey RS, Hope TJ.

J Virol. 2015 May;89(10):5569-80. doi: 10.1128/JVI.00309-15. Epub 2015 Mar 4.


Imaging endocervical mucus anatomy and dynamics in macaque female reproductive track using optical coherence tomography.

Chen S, Yi J, Dong B, Sun C, Kiser PF, Hope TJ, Zhang HF.

Quant Imaging Med Surg. 2015 Feb;5(1):40-5. doi: 10.3978/j.issn.2223-4292.2014.11.03.


Activation of microtubule dynamics increases neuronal growth via the nerve growth factor (NGF)- and Gαs-mediated signaling pathways.

Sarma T, Koutsouris A, Yu JZ, Krbanjevic A, Hope TJ, Rasenick MM.

J Biol Chem. 2015 Apr 17;290(16):10045-56. doi: 10.1074/jbc.M114.630632. Epub 2015 Feb 17.


Identification of a sustained neurogenic zone at the dorsal surface of the adult mouse hippocampus and its regulation by the chemokine SDF-1.

Belmadani A, Ren D, Bhattacharyya BJ, Rothwangl KB, Hope TJ, Perlman H, Miller RJ.

Hippocampus. 2015 Nov;25(11):1224-41. doi: 10.1002/hipo.22428. Epub 2015 Mar 27.


Novel three dimensional human endocervix cultures respond to 28-day hormone treatment.

Arslan SY, Yu Y, Burdette JE, Pavone ME, Hope TJ, Woodruff TK, Kim JJ.

Endocrinology. 2015 Apr;156(4):1602-9. doi: 10.1210/en.2014-1840. Epub 2015 Jan 30.


Progesterone-based intrauterine device use is associated with a thinner apical layer of the human ectocervical epithelium and a lower ZO-1 mRNA expression.

Tjernlund A, Carias AM, Andersson S, Gustafsson-Sanchez S, Röhl M, Petersson P, Introini A, Hope TJ, Broliden K.

Biol Reprod. 2015 Mar;92(3):68. doi: 10.1095/biolreprod.114.122887. Epub 2015 Jan 14.

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