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Items: 32


Zinc deficiency induces hypertension by promoting renal Na+ reabsorption.

Williams CR, Mistry M, Cheriyan AM, Williams JM, Naraine MK, Ellis CL, Mallick R, Mistry AC, Gooch JL, Ko B, Cai H, Hoover RS.

Am J Physiol Renal Physiol. 2019 Apr 1;316(4):F646-F653. doi: 10.1152/ajprenal.00487.2018. Epub 2019 Jan 16. Erratum in: Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F218-F219.


Protein kinase Cα deletion causes hypotension and decreased vascular contractility.

Wynne BM, McCarthy CG, Szasz T, Molina PA, Chapman AB, Webb RC, Klein JD, Hoover RS.

J Hypertens. 2018 Mar;36(3):510-519. doi: 10.1097/HJH.0000000000001596.


Regulation of Lung Epithelial Sodium Channels by Cytokines and Chemokines.

Wynne BM, Zou L, Linck V, Hoover RS, Ma HP, Eaton DC.

Front Immunol. 2017 Jul 25;8:766. doi: 10.3389/fimmu.2017.00766. eCollection 2017. Review.


Aldosterone Modulates the Association between NCC and ENaC.

Wynne BM, Mistry AC, Al-Khalili O, Mallick R, Theilig F, Eaton DC, Hoover RS.

Sci Rep. 2017 Jun 23;7(1):4149. doi: 10.1038/s41598-017-03510-5.


CD8+ T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension.

Liu Y, Rafferty TM, Rhee SW, Webber JS, Song L, Ko B, Hoover RS, He B, Mu S.

Nat Commun. 2017 Jan 9;8:14037. doi: 10.1038/ncomms14037.


NADPH oxidase-2 mediates zinc deficiency-induced oxidative stress and kidney damage.

Li MS, Adesina SE, Ellis CL, Gooch JL, Hoover RS, Williams CR.

Am J Physiol Cell Physiol. 2017 Jan 1;312(1):C47-C55. doi: 10.1152/ajpcell.00208.2016. Epub 2016 Nov 2.


WNK3 Kinase Enhances the Sodium Chloride Cotransporter Expression via an ERK 1/2 Signaling Pathway.

Wang D, Zhang Y, Han J, Pan S, Xu N, Feng X, Zhuang Z, Caroti C, Zhuang J, Hoover RS, Gu D, Zeng Q, Cai H.

Nephron. 2016;133(4):287-95. doi: 10.1159/000447717. Epub 2016 Jul 29.


The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate.

Mistry AC, Wynne BM, Yu L, Tomilin V, Yue Q, Zhou Y, Al-Khalili O, Mallick R, Cai H, Alli AA, Ko B, Mattheyses A, Bao HF, Pochynyuk O, Theilig F, Eaton DC, Hoover RS.

Biochem J. 2016 Oct 1;473(19):3237-52. doi: 10.1042/BCJ20160312. Epub 2016 Jul 15.


Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension.

Norlander AE, Saleh MA, Kamat NV, Ko B, Gnecco J, Zhu L, Dale BL, Iwakura Y, Hoover RS, McDonough AA, Madhur MS.

Hypertension. 2016 Jul;68(1):167-74. doi: 10.1161/HYPERTENSIONAHA.116.07493. Epub 2016 May 2.


PTH modulation of NCC activity regulates TRPV5 Ca2+ reabsorption.

Hoover RS, Tomilin V, Hanson L, Pochynyuk O, Ko B.

Am J Physiol Renal Physiol. 2016 Jan 15;310(2):F144-51. doi: 10.1152/ajprenal.00323.2015. Epub 2015 Nov 25.


Pendrin localizes to the adrenal medulla and modulates catecholamine release.

Lazo-Fernandez Y, Aguilera G, Pham TD, Park AY, Beierwaltes WH, Sutliff RL, Verlander JW, Pacak K, Osunkoya AO, Ellis CL, Kim YH, Shipley GL, Wynne BM, Hoover RS, Sen SK, Plotsky PM, Wall SM.

Am J Physiol Endocrinol Metab. 2015 Sep 15;309(6):E534-45. doi: 10.1152/ajpendo.00035.2015. Epub 2015 Jul 14. Erratum in: Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E885.


Mechanisms of angiotensin II stimulation of NCC are time-dependent in mDCT15 cells.

Ko B, Mistry A, Hanson L, Mallick R, Hoover RS.

Am J Physiol Renal Physiol. 2015 Apr 1;308(7):F720-7. doi: 10.1152/ajprenal.00465.2014. Epub 2015 Jan 28.


Compensatory renal hypertrophy following uninephrectomy is calcineurin-independent.

Williams CR, Wynne BM, Walker M, Hoover RS, Gooch JL.

J Cell Mol Med. 2014 Dec;18(12):2361-6. doi: 10.1111/jcmm.12438. Epub 2014 Oct 7.


A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter (NCC) and the with-no-lysine kinase (WNK) cascade in mouse distal convoluted tubule cells.

Richards J, Ko B, All S, Cheng KY, Hoover RS, Gumz ML.

J Biol Chem. 2014 Apr 25;289(17):11791-806. doi: 10.1074/jbc.M113.531095. Epub 2014 Mar 7.


Aldosterone acutely stimulates NCC activity via a SPAK-mediated pathway.

Ko B, Mistry AC, Hanson L, Mallick R, Wynne BM, Thai TL, Bailey JL, Klein JD, Hoover RS.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F645-52. doi: 10.1152/ajprenal.00053.2013. Epub 2013 Jun 5.


Insulin increases the functional activity of the renal NaCl cotransporter.

Chávez-Canales M, Arroyo JP, Ko B, Vázquez N, Bautista R, Castañeda-Bueno M, Bobadilla NA, Hoover RS, Gamba G.

J Hypertens. 2013 Feb;31(2):303-11. doi: 10.1097/HJH.0b013e32835bbb83.


A new model of the distal convoluted tubule.

Ko B, Mistry AC, Hanson L, Mallick R, Cooke LL, Hack BK, Cunningham P, Hoover RS.

Am J Physiol Renal Physiol. 2012 Sep;303(5):F700-10. doi: 10.1152/ajprenal.00139.2012. Epub 2012 Jun 20.


Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.

Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O.

J Am Soc Nephrol. 2011 Sep;22(9):1707-19. doi: 10.1681/ASN.2011020132. Epub 2011 Aug 18.


RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter.

Ko B, Kamsteeg EJ, Cooke LL, Moddes LN, Deen PM, Hoover RS.

Am J Physiol Renal Physiol. 2010 Aug;299(2):F300-9. doi: 10.1152/ajprenal.00441.2009. Epub 2010 Apr 14.


A physician becomes an attorney with a little advice: a case study.

Hoover RS.

Ann Health Law. 2010;19(1 Spec No):43-6. No abstract available.


Molecular physiology of the thiazide-sensitive sodium-chloride cotransporter.

Ko B, Hoover RS.

Curr Opin Nephrol Hypertens. 2009 Sep;18(5):421-7. doi: 10.1097/MNH.0b013e32832f2fcb. Review.


Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway.

Ko B, Joshi LM, Cooke LL, Vazquez N, Musch MW, Hebert SC, Gamba G, Hoover RS.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20120-5. Epub 2007 Dec 5.


cAMP-dependent activation of the renal-specific Na+-K+-2Cl- cotransporter is mediated by regulation of cotransporter trafficking.

Meade P, Hoover RS, Plata C, Vázquez N, Bobadilla NA, Gamba G, Hebert SC.

Am J Physiol Renal Physiol. 2003 Jun;284(6):F1145-54. Epub 2003 Feb 25.


N-Glycosylation at two sites critically alters thiazide binding and activity of the rat thiazide-sensitive Na(+):Cl(-) cotransporter.

Hoover RS, Poch E, Monroy A, Vázquez N, Nishio T, Gamba G, Hebert SC.

J Am Soc Nephrol. 2003 Feb;14(2):271-82.


Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.

Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):680-4. Epub 2003 Jan 6.


The electroneutral cation-chloride cotransporters.

Mount DB, Delpire E, Gamba G, Hall AE, Poch E, Hoover RS, Hebert SC.

J Exp Biol. 1998 Jul;201(Pt 14):2091-102. Review.


The molecular physiology of electroneutral cation-chloride cotransport.

Mount DB, Hoover RS, Hebert SC.

J Membr Biol. 1997 Aug 1;158(3):177-86. Review.


Feet of clay? Doctors are people, too.

Hoover RS.

IMJ Ill Med J. 1980 Apr;157(4):244-5. No abstract available.


Youth and chemical dependence.

Hoover RS.

IMJ Ill Med J. 1979 Jul;156(1):50-1. No abstract available.




J Iowa Med Soc. 1964 Mar;54:126-30. No abstract available.


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